TopFIND 4.0

Q8R4H7: N-acetylglutamate synthase, mitochondrial

General Information

Protein names
- N-acetylglutamate synthase, mitochondrial
- 2.3.1.1 {ECO:0000269|PubMed:12049647}
- Amino-acid acetyltransferase
- N-acetylglutamate synthase long form
- N-acetylglutamate synthase short form
- N-acetylglutamate synthase conserved domain form
Gene names Nags
Organism Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID Q8R4H7

4

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MATAWVATAL RSAAAARRLR SPGGPGGSRR LSGSARRRGA KSASPGRRLS TARAHAEDAE 
        70         80         90        100        110        120 
GAKGRVQSPA VEEPSWTPLP TPLESPAPPA GRSLVQRDIQ AFLNQCGASP GEARHWLTQF 
       130        140        150        160        170        180 
QTCYHSVDKP FAVMEVDEEV IRCPQAVSRL AFALAFLQRM DMKPLVVLGL PTPTAPSGCL 
       190        200        210        220        230        240 
SFWEAKAQLA QSCKVLVDEL RHNAATAVPF FGGGSVLSAA EPAPHASYGG IVAVETDLLQ 
       250        260        270        280        290        300 
WCLESNSIPI LCPIGETAAR RSVLLDSLEV TASLAKALQP TKIIFLNNSG GLRNNSQKIL 
       310        320        330        340        350        360 
SNVNLPADLD LVTNAEWLSI KERQQIRLIV DVLSRLPHYS SAVITAASTL LTELFSNKGC 
       370        380        390        400        410        420 
GTLFKNAERM LRVRNLDSLD QGRLVNLVNA SFGKKLREDY LESLRPRLHS IYVSEGYNAA 
       430        440        450        460        470        480 
AILTVEPVLG GTPYLDKFVV SSSRQGQGSG QMLWECLRRD LQTLFWRSRV TNPINPWYFK 
       490        500        510        520    
HSDGSFSNKQ WIFFWFGLAD IRDSYELVNH AKGLPDSFCK PASDPGS

Isoforms

- Isoform 2 of N-acetylglutamate synthase, mitochondrial

Sequence View

        10         20         30         40         50         60 
MATAWVATAL RSAAAARRLR SPGGPGGSRR LSGSARRRGA KSASPGRRLS TARAHAEDAE 
        70         80         90        100        110        120 
GAKGRVQSPA VEEPSWTPLP TPLESPAPPA GRSLVQRDIQ AFLNQCGASP GEARHWLTQF 
       130        140        150        160        170        180 
QTCYHSVDKP FAVMEVDEEV IRCPQAVSRL AFALAFLQRM DMKPLVVLGL PTPTAPSGCL 
       190        200        210        220        230        240 
SFWEAKAQLA QSCKVLVDEL RHNAATAVPF FGGGSVLSAA EPAPHASYGG IVAVETDLLQ 
       250        260        270        280        290        300 
WCLESNSIPI LCPIGETAAR RSVLLDSLEV TASLAKALQP TKIIFLNNSG GLRNNSQKIL 
       310        320        330        340        350        360 
SNVNLPADLD LVTNAEWLSI KERQQIRLIV DVLSRLPHYS SAVITAASTL LTELFSNKGC 
       370        380        390        400        410        420 
GTLFKNAERM LRVRNLDSLD QGRLVNLVNA SFGKKLREDY LESLRPRLHS IYVSEGYNAA 
       430        440        450        460        470        480 
AILTVEPVLG GTPYLDKFVV SSSRQGQGSG QMLWECLRRD LQTLFWRSRV TNPINPWYFK 
       490        500        510        520    
HSDGSFSNKQ WIFFWFGLAD IRDSYELVNH AKGLPDSFCK PASDPGS



Filter Information:


(REFRESH)

Directness:


Physiological Relevance:


Evidence Codes:


Methodology:


Perturbation of System:


Biological System:


Protease Assignment Confidence:


Evidence Names:


Database:


Lab:



Protein Neighborhood

Domains & Features

4 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    Q8R4H7-19-unknown LRSPGG... 19 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    Q8R4H7-51-unknown TARAHA... 51 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    Q8R4H7-84-unknown ESPAPP... 84 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    Q8R4H7-160-unknown MDMKPL... 160 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt82212

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...SDPGS 527 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    ...SDPGS 527 inferred from isoform by sequence similarity unknown TopFIND inferred from TCt77830

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)