TopFIND 4.0

Q8R4U6: DNA topoisomerase I, mitochondrial

General Information

Protein names
- DNA topoisomerase I, mitochondrial
- TOP1mt
- 5.6.2.2
Gene names Top1mt
Organism Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID Q8R4U6

1

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MLLLWLRALC RRFQHVPCRV PSCQVSRVAK ANRAGWEETS KSSVKWRQLE HKGPYFTPAY 
        70         80         90        100        110        120 
EPLPDGVHFL YDGKPLKLSL AAEEVATFYG KMLHLECTSK EVFRRNFFSD WRKEMTPEER 
       130        140        150        160        170        180 
RLITHLDKCD FTEIHKHFLE RAEARRTLPR EQKQKLKEEA EKLQQEFGYC VLDGHREKIG 
       190        200        210        220        230        240 
NFKTEPPGLF RGRGDHPKMG MLKRRVMPED VVINCSRDSK IPEPPAGHQW KEVRSDNTVM 
       250        260        270        280        290        300 
WLAAWVEHIQ NSFKYVILNP SSKPKGEMDW QKYEVARRLK GVVDKIRAQY QADWKSPEMK 
       310        320        330        340        350        360 
KRQLAVALYF IDKLALRTGN EKEEGETADT VGCCSLRVEH IRLHAPAGGQ EHVVELDFLG 
       370        380        390        400        410        420 
KDSIRYKNHV TVEKLVFQNL QHFMEDKDPR DDLFDALTTS SLNKHLQDLM EGLTAKVFRT 
       430        440        450        460        470        480 
YNASVTLQEQ LRVLTRAEDS VTCKVLAYNR ANRAVAVLCN HQRAVPKTFE KSMQTLQKKI 
       490        500        510        520        530        540 
ETKKAQVAEA QVELQKAETD LRMRGDSKPK SFLQKQRRLL KLEEQLARLC AKATDKEENK 
       550        560        570        580        590    
QVALGTAKLN YLDPRISIAW CKRFGVPVEK IYNKTQRERF AWAFNQAGED FEF

Isoforms



Sequence View



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Evidence Codes:


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Protease Assignment Confidence:


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Protein Neighborhood

Domains & Features

1 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...EDFEF 593 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)