Q8TAM2: Tetratricopeptide repeat protein 8

General Information

Protein names	- Tetratricopeptide repeat protein 8 - TPR repeat protein 8 - Bardet-Biedl syndrome 8 protein
Gene names	TTC8
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q8TAM2

2 N-termini

2 C-termini

0 Cleavages

0 Substrates

Sequence

Isoforms

- Isoform 2 of Tetratricopeptide repeat protein 8 - Isoform 3 of Tetratricopeptide repeat protein 8 - Isoform 4 of Tetratricopeptide repeat protein 8 - Isoform 5 of Tetratricopeptide repeat protein 8

Sequence View

        10         20         30         40         50         60
MSSEMEPLLL AWSYFRRRKF QLCADLCTQM LEKSPYDQEP DPELPVHQAA WILKARALTE
        70         80         90        100        110        120
MVYIDEIDVD QEGIAEMMLD ENAIAQVPRP GTSLKLPGTN QTGGPSQAVR PITQAGRPIT
       130        140        150        160        170        180
GFLRPSTQSG RPGTMEQAIR TPRTAYTARP ITSSSGRFVR LGTASMLTSP DGPFINLSRL
       190        200        210        220        230        240
NLTKYSQKPK LAKALFEYIF HHENDVKTIH LEDVVLHLGI YPFLLRNKNH IEKNALDLAA
       250        260        270        280        290        300
LSTEHSQYKD WWWKVQIGKC YYRLGMYREA EKQFKSALKQ QEMVDTFLYL AKVYVSLDQP
       310        320        330        340        350        360
VTALNLFKQG LDKFPGEVTL LCGIARIYEE MNNMSSAAEY YKEVLKQDNT HVEAIACIGS
       370        380        390        400        410        420
NHFYSDQPEI ALRFYRRLLQ MGIYNGQLFN NLGLCCFYAQ QYDMTLTSFE RALSLAENEE
       430        440        450        460        470        480
EAADVWYNLG HVAVGIGDTN LAHQCFRLAL VNNNNHAEAY NNLAVLEMRK GHVEQARALL
       490        500        510        520        530        540
QTASSLAPHM YEPHFNFATI SDKIGDLQRS YVAAQKSEAA FPDHVDTQHL IKQLRQHFAM

L         10         20         30         40         50         60
MSSEMEPLLL AWSYFRRRKF QLCADLCTQM LEKSPYDQEP DPELPVHQAA WILKARALTE
        70         80         90        100        110        120
MVYIDEIDVD QEGIAEMMLD ENAIAQVPRP GTSLKLPGTN QTGGPSQAVR PITQAGRPIT
       130        140        150        160        170        180
GFLRPSTQSG RPGTMEQAIR TPRTAYTARP ITSSSGRFVR LGTASMLTSP DGPFINLSRL
       190        200        210        220        230        240
NLTKYSQKPK LAKALFEYIF HHENDVKTIH LEDVVLHLGI YPFLLRNKNH IEKNALDLAA
       250        260        270        280        290        300
LSTEHSQYKD WWWKVQIGKC YYRLGMYREA EKQFKSALKQ QEMVDTFLYL AKVYVSLDQP
       310        320        330        340        350        360
VTALNLFKQG LDKFPGEVTL LCGIARIYEE MNNMSSAAEY YKEVLKQDNT HVEAIACIGS
       370        380        390        400        410        420
NHFYSDQPEI ALRFYRRLLQ MGIYNGQLFN NLGLCCFYAQ QYDMTLTSFE RALSLAENEE
       430        440        450        460        470        480
EAADVWYNLG HVAVGIGDTN LAHQCFRLAL VNNNNHAEAY NNLAVLEMRK GHVEQARALL
       490        500        510        520        530        540
QTASSLAPHM YEPHFNFATI SDKIGDLQRS YVAAQKSEAA FPDHVDTQHL IKQLRQHFAM

L         10         20         30         40         50         60
MSSEMEPLLL AWSYFRRRKF QLCADLCTQM LEKSPYDQEP DPELPVHQAA WILKARALTE
        70         80         90        100        110        120
MVYIDEIDVD QEGIAEMMLD ENAIAQVPRP GTSLKLPGTN QTGGPSQAVR PITQAGRPIT
       130        140        150        160        170        180
GFLRPSTQSG RPGTMEQAIR TPRTAYTARP ITSSSGRFVR LGTASMLTSP DGPFINLSRL
       190        200        210        220        230        240
NLTKYSQKPK LAKALFEYIF HHENDVKTIH LEDVVLHLGI YPFLLRNKNH IEKNALDLAA
       250        260        270        280        290        300
LSTEHSQYKD WWWKVQIGKC YYRLGMYREA EKQFKSALKQ QEMVDTFLYL AKVYVSLDQP
       310        320        330        340        350        360
VTALNLFKQG LDKFPGEVTL LCGIARIYEE MNNMSSAAEY YKEVLKQDNT HVEAIACIGS
       370        380        390        400        410        420
NHFYSDQPEI ALRFYRRLLQ MGIYNGQLFN NLGLCCFYAQ QYDMTLTSFE RALSLAENEE
       430        440        450        460        470        480
EAADVWYNLG HVAVGIGDTN LAHQCFRLAL VNNNNHAEAY NNLAVLEMRK GHVEQARALL
       490        500        510        520        530        540
QTASSLAPHM YEPHFNFATI SDKIGDLQRS YVAAQKSEAA FPDHVDTQHL IKQLRQHFAM

L         10         20         30         40         50         60
MSSEMEPLLL AWSYFRRRKF QLCADLCTQM LEKSPYDQEP DPELPVHQAA WILKARALTE
        70         80         90        100        110        120
MVYIDEIDVD QEGIAEMMLD ENAIAQVPRP GTSLKLPGTN QTGGPSQAVR PITQAGRPIT
       130        140        150        160        170        180
GFLRPSTQSG RPGTMEQAIR TPRTAYTARP ITSSSGRFVR LGTASMLTSP DGPFINLSRL
       190        200        210        220        230        240
NLTKYSQKPK LAKALFEYIF HHENDVKTIH LEDVVLHLGI YPFLLRNKNH IEKNALDLAA
       250        260        270        280        290        300
LSTEHSQYKD WWWKVQIGKC YYRLGMYREA EKQFKSALKQ QEMVDTFLYL AKVYVSLDQP
       310        320        330        340        350        360
VTALNLFKQG LDKFPGEVTL LCGIARIYEE MNNMSSAAEY YKEVLKQDNT HVEAIACIGS
       370        380        390        400        410        420
NHFYSDQPEI ALRFYRRLLQ MGIYNGQLFN NLGLCCFYAQ QYDMTLTSFE RALSLAENEE
       430        440        450        460        470        480
EAADVWYNLG HVAVGIGDTN LAHQCFRLAL VNNNNHAEAY NNLAVLEMRK GHVEQARALL
       490        500        510        520        530        540
QTASSLAPHM YEPHFNFATI SDKIGDLQRS YVAAQKSEAA FPDHVDTQHL IKQLRQHFAM

L

Filter Information:

(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

2 N-termini - 2 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Evidence name
Q8TAM2-1-unknown	MSSEME...	1	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
Q8TAM2-1-unknown	MSSEME...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt93376
Q8TAM2-1-unknown	MSSEME...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt93377
Q8TAM2-1-unknown	MSSEME...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt93378
Q8TAM2-1-unknown	MSSEME...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt93379
Q8TAM2-266-unknown	MYREAE...	266	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000445067
Q8TAM2-266-unknown	MYREAE...	266	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt129529
Q8TAM2-266-unknown	MYREAE...	266	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt129530

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...ATISDK	502	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000451955
...ATISDK	502	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt107865
...ATISDK	502	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt107866
...ATISDK	502	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt107867
...HFAML	541	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...HFAML	541	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt88994
...HFAML	541	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt88995
...HFAML	541	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt88996

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)