TopFIND 4.0

Q8TBB1: E3 ubiquitin-protein ligase LNX

General Information

Protein names
- E3 ubiquitin-protein ligase LNX
- 2.3.2.27
- Ligand of Numb-protein X 1
- Numb-binding protein 1
- PDZ domain-containing RING finger protein 2
- RING-type E3 ubiquitin transferase LNX {ECO:0000305}
Gene names LNX1
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID Q8TBB1

1

N-termini

4

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MNQPESANDP EPLCAVCGQA HSLEENHFYS YPEEVDDDLI CHICLQALLD PLDTPCGHTY 
        70         80         90        100        110        120 
CTLCLTNFLV EKDFCPMDRK PLVLQHCKKS SILVNKLLNK LLVTCPFREH CTQVLQRCDL 
       130        140        150        160        170        180 
EHHFQTSCKG ASHYGLTKDR KRRSQDGCPD GCASLTATAP SPEVSAAATI SLMTDEPGLD 
       190        200        210        220        230        240 
NPAYVSSAED GQPAISPVDS GRSNRTRARP FERSTIRSRS FKKINRALSV LRRTKSGSAV 
       250        260        270        280        290        300 
ANHADQGREN SENTTAPEVF PRLYHLIPDG EITSIKINRV DPSESLSIRL VGGSETPLVH 
       310        320        330        340        350        360 
IIIQHIYRDG VIARDGRLLP GDIILKVNGM DISNVPHNYA VRLLRQPCQV LWLTVMREQK 
       370        380        390        400        410        420 
FRSRNNGQAP DAYRPRDDSF HVILNKSSPE EQLGIKLVRK VDEPGVFIFN VLDGGVAYRH 
       430        440        450        460        470        480 
GQLEENDRVL AINGHDLRYG SPESAAHLIQ ASERRVHLVV SRQVRQRSPD IFQEAGWNSN 
       490        500        510        520        530        540 
GSWSPGPGER SNTPKPLHPT ITCHEKVVNI QKDPGESLGM TVAGGASHRE WDLPIYVISV 
       550        560        570        580        590        600 
EPGGVISRDG RIKTGDILLN VDGVELTEVS RSEAVALLKR TSSSIVLKAL EVKEYEPQED 
       610        620        630        640        650        660 
CSSPAALDSN HNMAPPSDWS PSWVMWLELP RCLYNCKDIV LRRNTAGSLG FCIVGGYEEY 
       670        680        690        700        710        720 
NGNKPFFIKS IVEGTPAYND GRIRCGDILL AVNGRSTSGM IHACLARLLK ELKGRITLTI 
   
VSWPGTFL

Isoforms

- Isoform 2 of E3 ubiquitin-protein ligase LNX

Sequence View

        10         20         30         40         50         60 
MNQPESANDP EPLCAVCGQA HSLEENHFYS YPEEVDDDLI CHICLQALLD PLDTPCGHTY 
        70         80         90        100        110        120 
CTLCLTNFLV EKDFCPMDRK PLVLQHCKKS SILVNKLLNK LLVTCPFREH CTQVLQRCDL 
       130        140        150        160        170        180 
EHHFQTSCKG ASHYGLTKDR KRRSQDGCPD GCASLTATAP SPEVSAAATI SLMTDEPGLD 
       190        200        210        220        230        240 
NPAYVSSAED GQPAISPVDS GRSNRTRARP FERSTIRSRS FKKINRALSV LRRTKSGSAV 
       250        260        270        280        290        300 
ANHADQGREN SENTTAPEVF PRLYHLIPDG EITSIKINRV DPSESLSIRL VGGSETPLVH 
       310        320        330        340        350        360 
IIIQHIYRDG VIARDGRLLP GDIILKVNGM DISNVPHNYA VRLLRQPCQV LWLTVMREQK 
       370        380        390        400        410        420 
FRSRNNGQAP DAYRPRDDSF HVILNKSSPE EQLGIKLVRK VDEPGVFIFN VLDGGVAYRH 
       430        440        450        460        470        480 
GQLEENDRVL AINGHDLRYG SPESAAHLIQ ASERRVHLVV SRQVRQRSPD IFQEAGWNSN 
       490        500        510        520        530        540 
GSWSPGPGER SNTPKPLHPT ITCHEKVVNI QKDPGESLGM TVAGGASHRE WDLPIYVISV 
       550        560        570        580        590        600 
EPGGVISRDG RIKTGDILLN VDGVELTEVS RSEAVALLKR TSSSIVLKAL EVKEYEPQED 
       610        620        630        640        650        660 
CSSPAALDSN HNMAPPSDWS PSWVMWLELP RCLYNCKDIV LRRNTAGSLG FCIVGGYEEY 
       670        680        690        700        710        720 
NGNKPFFIKS IVEGTPAYND GRIRCGDILL AVNGRSTSGM IHACLARLLK ELKGRITLTI 
   
VSWPGTFL



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Evidence Names:


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Protein Neighborhood

Domains & Features

1 N-termini - 4 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    Q8TBB1-1-unknown MNQPES... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

C-termini

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)