TopFIND 4.0

Q8TBK2: N-lysine methyltransferase SETD6

General Information

Protein names
- N-lysine methyltransferase SETD6
- 2.1.1.-
- SET domain-containing protein 6
Gene names SETD6
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID Q8TBK2

1

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MATQAKRPRV AGPVDGGDLD PVACFLSWCR RVGLELSPKV SERAGGRRTR GGARAALTSP 
        70         80         90        100        110        120 
PAQVAVSRQG TVAGYGMVAR ESVQAGELLF VVPRAALLSQ HTCSIGGLLE RERVALQSQS 
       130        140        150        160        170        180 
GWVPLLLALL HELQAPASRW RPYFALWPEL GRLEHPMFWP EEERRCLLQG TGVPEAVEKD 
       190        200        210        220        230        240 
LANIRSEYQS IVLPFMEAHP DLFSLRVRSL ELYHQLVALV MAYSFQEPLE EEEDEKEPNS 
       250        260        270        280        290        300 
PVMVPAADIL NHLANHNANL EYSANCLRMV ATQPIPKGHE IFNTYGQMAN WQLIHMYGFV 
       310        320        330        340        350        360 
EPYPDNTDDT ADIQMVTVRE AALQGTKTEA ERHLVYERWD FLCKLEMVGE EGAFVIGREE 
       370        380        390        400        410        420 
VLTEEELTTT LKVLCMPAEE FRELKDQDGG GDDKREEGSL TITNIPKLKA SWRQLLQNSV 
       430        440        450        460        470    
LLTLQTYATD LKTDQGLLSN KEVYAKLSWR EQQALQVRYG QKMILHQLLE LTS

Isoforms

- Isoform 2 of N-lysine methyltransferase SETD6

Sequence View

        10         20         30         40         50         60 
MATQAKRPRV AGPVDGGDLD PVACFLSWCR RVGLELSPKV SERAGGRRTR GGARAALTSP 
        70         80         90        100        110        120 
PAQVAVSRQG TVAGYGMVAR ESVQAGELLF VVPRAALLSQ HTCSIGGLLE RERVALQSQS 
       130        140        150        160        170        180 
GWVPLLLALL HELQAPASRW RPYFALWPEL GRLEHPMFWP EEERRCLLQG TGVPEAVEKD 
       190        200        210        220        230        240 
LANIRSEYQS IVLPFMEAHP DLFSLRVRSL ELYHQLVALV MAYSFQEPLE EEEDEKEPNS 
       250        260        270        280        290        300 
PVMVPAADIL NHLANHNANL EYSANCLRMV ATQPIPKGHE IFNTYGQMAN WQLIHMYGFV 
       310        320        330        340        350        360 
EPYPDNTDDT ADIQMVTVRE AALQGTKTEA ERHLVYERWD FLCKLEMVGE EGAFVIGREE 
       370        380        390        400        410        420 
VLTEEELTTT LKVLCMPAEE FRELKDQDGG GDDKREEGSL TITNIPKLKA SWRQLLQNSV 
       430        440        450        460        470    
LLTLQTYATD LKTDQGLLSN KEVYAKLSWR EQQALQVRYG QKMILHQLLE LTS



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Protein Neighborhood

Domains & Features

1 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    Q8TBK2-1-unknown MATQAK... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    Q8TBK2-1-unknown MATQAK... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt89362

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...LELTS 473 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    ...LELTS 473 inferred from isoform by sequence similarity unknown TopFIND inferred from TCt84980

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)