Q8TBZ3: WD repeat-containing protein 20

General Information

Protein names	- WD repeat-containing protein 20 - Protein DMR
Gene names	WDR20
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q8TBZ3

4 N-termini

1 C-termini

0 Cleavages

0 Substrates

Sequence

Isoforms

- Isoform 2 of WD repeat-containing protein 20 - Isoform 3 of WD repeat-containing protein 20 - Isoform 4 of WD repeat-containing protein 20 - Isoform 5 of WD repeat-containing protein 20 - Isoform 6 of WD repeat-containing protein 20 - Isoform 7 of WD repeat-containing protein 20 - Isoform 8 of WD repeat-containing protein 20

Sequence View

        10         20         30         40         50         60
MATEGGGKEM NEIKTQFTTR EGLYKLLPHS EYSRPNRVPF NSQGSNPVRV SFVNLNDQSG
        70         80         90        100        110        120
NGDRLCFNVG RELYFYIYKG VRKAADLSKP IDKRIYKGTQ PTCHDFNHLT ATAESVSLLV
       130        140        150        160        170        180
GFSAGQVQLI DPIKKETSKL FNEERLIDKS RVTCVKWVPG SESLFLVAHS SGNMYLYNVE
       190        200        210        220        230        240
HTCGTTAPHY QLLKQGESFA VHTCKSKSTR NPLLKWTVGE GALNEFAFSP DGKFLACVSQ
       250        260        270        280        290        300
DGFLRVFNFD SVELHGTMKS YFGGLLCVCW SPDGKYIVTG GEDDLVTVWS FVDCRVIARG
       310        320        330        340        350        360
HGHKSWVSVV AFDPYTTSVE EGDPMEFSGS DEDFQDLLHF GRDRANSTQS RLSKRNSTDS
       370        380        390        400        410        420
RPVSVTYRFG SVGQDTQLCL WDLTEDILFP HQPLSRARTH TNVMNATSPP AGSNGNSVTT
       430        440        450        460        470        480
PGNSVPPPLP RSNSLPHSAV SNAGSKSSVM DGAIASGVSK FATLSLHDRK ERHHEKDHKR
       490        500        510        520        530        540
NHSMGHISSK SSDKLNLVTK TKTDPAKTLG TPLCPRMEDV PLLEPLICKK IAHERLTVLI
       550        560
FLEDCIVTAC QEGFICTWGR PGKVVSFNP         10         20         30         40         50         60
MATEGGGKEM NEIKTQFTTR EGLYKLLPHS EYSRPNRVPF NSQGSNPVRV SFVNLNDQSG
        70         80         90        100        110        120
NGDRLCFNVG RELYFYIYKG VRKAADLSKP IDKRIYKGTQ PTCHDFNHLT ATAESVSLLV
       130        140        150        160        170        180
GFSAGQVQLI DPIKKETSKL FNEERLIDKS RVTCVKWVPG SESLFLVAHS SGNMYLYNVE
       190        200        210        220        230        240
HTCGTTAPHY QLLKQGESFA VHTCKSKSTR NPLLKWTVGE GALNEFAFSP DGKFLACVSQ
       250        260        270        280        290        300
DGFLRVFNFD SVELHGTMKS YFGGLLCVCW SPDGKYIVTG GEDDLVTVWS FVDCRVIARG
       310        320        330        340        350        360
HGHKSWVSVV AFDPYTTSVE EGDPMEFSGS DEDFQDLLHF GRDRANSTQS RLSKRNSTDS
       370        380        390        400        410        420
RPVSVTYRFG SVGQDTQLCL WDLTEDILFP HQPLSRARTH TNVMNATSPP AGSNGNSVTT
       430        440        450        460        470        480
PGNSVPPPLP RSNSLPHSAV SNAGSKSSVM DGAIASGVSK FATLSLHDRK ERHHEKDHKR
       490        500        510        520        530        540
NHSMGHISSK SSDKLNLVTK TKTDPAKTLG TPLCPRMEDV PLLEPLICKK IAHERLTVLI
       550        560
FLEDCIVTAC QEGFICTWGR PGKVVSFNP         10         20         30         40         50         60
MATEGGGKEM NEIKTQFTTR EGLYKLLPHS EYSRPNRVPF NSQGSNPVRV SFVNLNDQSG
        70         80         90        100        110        120
NGDRLCFNVG RELYFYIYKG VRKAADLSKP IDKRIYKGTQ PTCHDFNHLT ATAESVSLLV
       130        140        150        160        170        180
GFSAGQVQLI DPIKKETSKL FNEERLIDKS RVTCVKWVPG SESLFLVAHS SGNMYLYNVE
       190        200        210        220        230        240
HTCGTTAPHY QLLKQGESFA VHTCKSKSTR NPLLKWTVGE GALNEFAFSP DGKFLACVSQ
       250        260        270        280        290        300
DGFLRVFNFD SVELHGTMKS YFGGLLCVCW SPDGKYIVTG GEDDLVTVWS FVDCRVIARG
       310        320        330        340        350        360
HGHKSWVSVV AFDPYTTSVE EGDPMEFSGS DEDFQDLLHF GRDRANSTQS RLSKRNSTDS
       370        380        390        400        410        420
RPVSVTYRFG SVGQDTQLCL WDLTEDILFP HQPLSRARTH TNVMNATSPP AGSNGNSVTT
       430        440        450        460        470        480
PGNSVPPPLP RSNSLPHSAV SNAGSKSSVM DGAIASGVSK FATLSLHDRK ERHHEKDHKR
       490        500        510        520        530        540
NHSMGHISSK SSDKLNLVTK TKTDPAKTLG TPLCPRMEDV PLLEPLICKK IAHERLTVLI
       550        560
FLEDCIVTAC QEGFICTWGR PGKVVSFNP         10         20         30         40         50         60
MATEGGGKEM NEIKTQFTTR EGLYKLLPHS EYSRPNRVPF NSQGSNPVRV SFVNLNDQSG
        70         80         90        100        110        120
NGDRLCFNVG RELYFYIYKG VRKAADLSKP IDKRIYKGTQ PTCHDFNHLT ATAESVSLLV
       130        140        150        160        170        180
GFSAGQVQLI DPIKKETSKL FNEERLIDKS RVTCVKWVPG SESLFLVAHS SGNMYLYNVE
       190        200        210        220        230        240
HTCGTTAPHY QLLKQGESFA VHTCKSKSTR NPLLKWTVGE GALNEFAFSP DGKFLACVSQ
       250        260        270        280        290        300
DGFLRVFNFD SVELHGTMKS YFGGLLCVCW SPDGKYIVTG GEDDLVTVWS FVDCRVIARG
       310        320        330        340        350        360
HGHKSWVSVV AFDPYTTSVE EGDPMEFSGS DEDFQDLLHF GRDRANSTQS RLSKRNSTDS
       370        380        390        400        410        420
RPVSVTYRFG SVGQDTQLCL WDLTEDILFP HQPLSRARTH TNVMNATSPP AGSNGNSVTT
       430        440        450        460        470        480
PGNSVPPPLP RSNSLPHSAV SNAGSKSSVM DGAIASGVSK FATLSLHDRK ERHHEKDHKR
       490        500        510        520        530        540
NHSMGHISSK SSDKLNLVTK TKTDPAKTLG TPLCPRMEDV PLLEPLICKK IAHERLTVLI
       550        560
FLEDCIVTAC QEGFICTWGR PGKVVSFNP         10         20         30         40         50         60
MATEGGGKEM NEIKTQFTTR EGLYKLLPHS EYSRPNRVPF NSQGSNPVRV SFVNLNDQSG
        70         80         90        100        110        120
NGDRLCFNVG RELYFYIYKG VRKAADLSKP IDKRIYKGTQ PTCHDFNHLT ATAESVSLLV
       130        140        150        160        170        180
GFSAGQVQLI DPIKKETSKL FNEERLIDKS RVTCVKWVPG SESLFLVAHS SGNMYLYNVE
       190        200        210        220        230        240
HTCGTTAPHY QLLKQGESFA VHTCKSKSTR NPLLKWTVGE GALNEFAFSP DGKFLACVSQ
       250        260        270        280        290        300
DGFLRVFNFD SVELHGTMKS YFGGLLCVCW SPDGKYIVTG GEDDLVTVWS FVDCRVIARG
       310        320        330        340        350        360
HGHKSWVSVV AFDPYTTSVE EGDPMEFSGS DEDFQDLLHF GRDRANSTQS RLSKRNSTDS
       370        380        390        400        410        420
RPVSVTYRFG SVGQDTQLCL WDLTEDILFP HQPLSRARTH TNVMNATSPP AGSNGNSVTT
       430        440        450        460        470        480
PGNSVPPPLP RSNSLPHSAV SNAGSKSSVM DGAIASGVSK FATLSLHDRK ERHHEKDHKR
       490        500        510        520        530        540
NHSMGHISSK SSDKLNLVTK TKTDPAKTLG TPLCPRMEDV PLLEPLICKK IAHERLTVLI
       550        560
FLEDCIVTAC QEGFICTWGR PGKVVSFNP         10         20         30         40         50         60
MATEGGGKEM NEIKTQFTTR EGLYKLLPHS EYSRPNRVPF NSQGSNPVRV SFVNLNDQSG
        70         80         90        100        110        120
NGDRLCFNVG RELYFYIYKG VRKAADLSKP IDKRIYKGTQ PTCHDFNHLT ATAESVSLLV
       130        140        150        160        170        180
GFSAGQVQLI DPIKKETSKL FNEERLIDKS RVTCVKWVPG SESLFLVAHS SGNMYLYNVE
       190        200        210        220        230        240
HTCGTTAPHY QLLKQGESFA VHTCKSKSTR NPLLKWTVGE GALNEFAFSP DGKFLACVSQ
       250        260        270        280        290        300
DGFLRVFNFD SVELHGTMKS YFGGLLCVCW SPDGKYIVTG GEDDLVTVWS FVDCRVIARG
       310        320        330        340        350        360
HGHKSWVSVV AFDPYTTSVE EGDPMEFSGS DEDFQDLLHF GRDRANSTQS RLSKRNSTDS
       370        380        390        400        410        420
RPVSVTYRFG SVGQDTQLCL WDLTEDILFP HQPLSRARTH TNVMNATSPP AGSNGNSVTT
       430        440        450        460        470        480
PGNSVPPPLP RSNSLPHSAV SNAGSKSSVM DGAIASGVSK FATLSLHDRK ERHHEKDHKR
       490        500        510        520        530        540
NHSMGHISSK SSDKLNLVTK TKTDPAKTLG TPLCPRMEDV PLLEPLICKK IAHERLTVLI
       550        560
FLEDCIVTAC QEGFICTWGR PGKVVSFNP         10         20         30         40         50         60
MATEGGGKEM NEIKTQFTTR EGLYKLLPHS EYSRPNRVPF NSQGSNPVRV SFVNLNDQSG
        70         80         90        100        110        120
NGDRLCFNVG RELYFYIYKG VRKAADLSKP IDKRIYKGTQ PTCHDFNHLT ATAESVSLLV
       130        140        150        160        170        180
GFSAGQVQLI DPIKKETSKL FNEERLIDKS RVTCVKWVPG SESLFLVAHS SGNMYLYNVE
       190        200        210        220        230        240
HTCGTTAPHY QLLKQGESFA VHTCKSKSTR NPLLKWTVGE GALNEFAFSP DGKFLACVSQ
       250        260        270        280        290        300
DGFLRVFNFD SVELHGTMKS YFGGLLCVCW SPDGKYIVTG GEDDLVTVWS FVDCRVIARG
       310        320        330        340        350        360
HGHKSWVSVV AFDPYTTSVE EGDPMEFSGS DEDFQDLLHF GRDRANSTQS RLSKRNSTDS
       370        380        390        400        410        420
RPVSVTYRFG SVGQDTQLCL WDLTEDILFP HQPLSRARTH TNVMNATSPP AGSNGNSVTT
       430        440        450        460        470        480
PGNSVPPPLP RSNSLPHSAV SNAGSKSSVM DGAIASGVSK FATLSLHDRK ERHHEKDHKR
       490        500        510        520        530        540
NHSMGHISSK SSDKLNLVTK TKTDPAKTLG TPLCPRMEDV PLLEPLICKK IAHERLTVLI
       550        560
FLEDCIVTAC QEGFICTWGR PGKVVSFNP

Filter Information:

(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

4 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
Q8TBZ3-2-unknown	MATEGG...	1		inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q8TBZ3-1-unknown	MATEGG...	1		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt94415
Q8TBZ3-1-unknown	MATEGG...	1		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt94416
Q8TBZ3-1-unknown	MATEGG...	1		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt94418
Q8TBZ3-1-unknown	MATEGG...	1		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt94419
Q8TBZ3-1-unknown	MATEGG...	1		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt94420
Q8TBZ3-1-unknown	MATEGG...	1		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt94421
Q8TBZ3-2-Acetylation	ATEGGG...	2	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q8TBZ3-2-Acetylation	ATEGGG...	2	acetylation-		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345
Q8TBZ3-2-Acetylation	ATEGGG...	2	acetylation-	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt111215
Q8TBZ3-2-Acetylation	ATEGGG...	2	acetylation-	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt111216
Q8TBZ3-2-Acetylation	ATEGGG...	2	acetylation-	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt111217
Q8TBZ3-2-Acetylation	ATEGGG...	2	acetylation-	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt111218
Q8TBZ3-2-Acetylation	ATEGGG...	2	acetylation-	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt111219
Q8TBZ3-2-Acetylation	ATEGGG...	2	acetylation-	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt111220
Q8TBZ3-10-unknown	MNEIKT...	10		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt94417
Q8TBZ3-10-unknown	MNEIKT...	10		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt107615
Q8TBZ3-10-unknown	MNEIKT...	10		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt107616
Q8TBZ3-10-unknown	MNEIKT...	10		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt107617
Q8TBZ3-10-unknown	MNEIKT...	10		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt107618
Q8TBZ3-10-unknown	MNEIKT...	10		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt107619
Q8TBZ3-10-unknown	MNEIKT...	10		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt107620

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
...VSFNP	569	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
...VSFNP	569	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt90035
...VSFNP	569	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt90036
...VSFNP	569	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt90038
...VSFNP	569		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345,

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)