Q8TCU4: Alstrom syndrome protein 1
| Protein names | - Alstrom syndrome protein 1 |
|---|---|
| Gene names | ALMS1 |
| Organism | Homo sapiens |
| Protease Family | |
| Protease ID | |
| Chromosome location | |
| UniProt ID | Q8TCU4 |
3
N-termini
2
C-termini
0
Cleavages
0
Substrates
Sequence
10 20 30 40 50 60
MEPEDLPWPG ELEEEEEEEE EEEEEEEEAA AAAAANVDDV VVVEEVEEEA GRELDSDSHY
70 80 90 100 110 120
GPQHLESIDD EEDEEAKAWL QAHPGRILPP LSPPQHRYSE GERTSLEKIV PLTCHVWQQI
130 140 150 160 170 180
VYQGNSRTQI SDTNVVCLET TAQRGSGDDQ KTESWHCLPQ EMDSSQTLDT SQTRFNVRTE
190 200 210 220 230 240
DTEVTDFPSL EEGILTQSEN QVKEPNRDLF CSPLLVIQDS FASPDLPLLT CLTQDQEFAP
250 260 270 280 290 300
DSLFHQSELS FAPLRGIPDK SEDTEWSSRP SEVSEALFQA TAEVASDLAS SRFSVSQHPL
310 320 330 340 350 360
IGSTAVGSQC PFLPSEQGNN EETISSVDEL KIPKDCDRYD DLCSYMSWKT RKDTQWPENN
370 380 390 400 410 420
LADKDQVSVA TSFDITDENI ATKRSDHFDA ARSYGQYWTQ EDSSKQAETY LTKGLQGKVE
430 440 450 460 470 480
SDVITLDGLN ENAVVCSERV AELQRKPTRE SEYHSSDLRM LRMSPDTVPK APKHLKAGDT
490 500 510 520 530 540
SKGGIAKVTQ SNLKSGITTT PVDSDIGSHL SLSLEDLSQL AVSSPLETTT GQHTDTLNQK
550 560 570 580 590 600
TLADTHLTEE TLKVTAIPEP ADQKTATPTV LSSSHSHRGK PSIFYQQGLP DSHLTEEALK
610 620 630 640 650 660
VSAAPGLADQ TTGMSTLTST SYSHREKPGT FYQQELPESN LTEEPLEVSA APGPVEQKTG
670 680 690 700 710 720
IPTVSSTSHS HVEDLLFFYR QTLPDGHLTD QALKVSAVSG PADQKTGTAT VLSTPHSHRE
730 740 750 760 770 780
KPGIFYQQEF ADSHQTEETL TKVSATPGPA DQKTEIPAVQ SSSYSQREKP SILYPQDLAD
790 800 810 820 830 840
SHLPEEGLKV SAVAGPADQK TGLPTVPSSA YSHREKLLVF YQQALLDSHL PEEALKVSAV
850 860 870 880 890 900
SGPADGKTGT PAVTSTSSAS SSLGEKPSAF YQQTLPNSHL TEEALKVSIV PGPGDQKTGI
910 920 930 940 950 960
PSAPSSFYSH REKPIIFSQQ TLPDFLFPEE ALKVSAVSVL AAQKTGTPTV SSNSHSHSEK
970 980 990 1000 1010 1020
SSVFYQQELP DSDLPRESLK MSAIPGLTDQ KTVPTPTVPS GSFSHREKPS IFYQQEWPDS
1030 1040 1050 1060 1070 1080
YATEKALKVS TGPGPADQKT EIPAVQSSSY PQREKPSVLY PQVLSDSHLP EESLKVSAFP
1090 1100 1110 1120 1130 1140
GPADQMTDTP AVPSTFYSQR EKPGIFYQQT LPESHLPKEA LKISVAPGLA DQKTGTPTVT
1150 1160 1170 1180 1190 1200
STSYSQHREK PSIFHQQALP GTHIPEEAQK VSAVTGPGNQ KTWIPRVLST FYSQREKPGI
1210 1220 1230 1240 1250 1260
FYQQTLPGSH IPEEAQKVSP VLGPADQKTG TPTPTSASYS HTEKPGIFYQ QVLPDNHPTE
1270 1280 1290 1300 1310 1320
EALKISVASE PVDQTTGTPA VTSTSYSQYR EKPSIFYQQS LPSSHLTEEA KNVSAVPGPA
1330 1340 1350 1360 1370 1380
DQKTVIPILP STFYSHTEKP GVFYQQVLPH SHPTEEALKI SVASEPVDQT TGTPTVTSTS
1390 1400 1410 1420 1430 1440
YSQHTEKPSI FYQQSLPGSH LTEEAKNVSA VPGPGDRKTG IPTLPSTFYS HTEKPGSFYQ
1450 1460 1470 1480 1490 1500
QVLPHSHLPE EALEVSVAPG PVDQTIGTPT VTSPSSSFGE KPIVIYKQAF PEGHLPEESL
1510 1520 1530 1540 1550 1560
KVSVAPGPVG QTTGAPTITS PSYSQHRAKS GSFYQLALLG SQIPEEALRV SSAPGPADQT
1570 1580 1590 1600 1610 1620
TGIPTITSTS YSFGEKPIVN YKQAFPDGHL PEEALKVSIV SGPTEKKTDI PAGPLGSSAL
1630 1640 1650 1660 1670 1680
GEKPITFYRQ ALLDSPLNKE VVKVSAAPGP ADQKTETLPV HSTSYSNRGK PVIFYQQTLS
1690 1700 1710 1720 1730 1740
DSHLPEEALK VPPVPGPDAQ KTETPSVSSS LYSYREKPIV FYQQALPDSE LTQEALKVSA
1750 1760 1770 1780 1790 1800
VPQPADQKTG LSTVTSSFYS HTEKPNISYQ QELPDSHLTE EALKVSNVPG PADQKTGVST
1810 1820 1830 1840 1850 1860
VTSTSYSHRE KPIVSYQREL PHFTEAGLKI LRVPGPADQK TGINILPSNS YPQREHSVIS
1870 1880 1890 1900 1910 1920
YEQELPDLTE VTLKAIGVPG PADQKTGIQI ASSSSYSNRE KASIFHQQEL PDVTEEALNV
1930 1940 1950 1960 1970 1980
FVVPGQGDRK TEIPTVPLSY YSRREKPSVI SQQELPDSHL TEEALKVSPV SIPAEQKTGI
1990 2000 2010 2020 2030 2040
PIGLSSSYSH SHKEKLKIST VHIPDDQKTE FPAATLSSYS QIEKPKISTV IGPNDQKTPS
2050 2060 2070 2080 2090 2100
QTAFHSSYSQ TVKPNILFQQ QLPDRDQSKG ILKISAVPEL TDVNTGKPVS LSSSYFHREK
2110 2120 2130 2140 2150 2160
SNIFSPQELP GSHVTEDVLK VSTIPGPAGQ KTVLPTALPS SFSHREKPDI FYQKDLPDRH
2170 2180 2190 2200 2210 2220
LTEDALKISS ALGQADQITG LQTVPSGTYS HGENHKLVSE HVQRLIDNLN SSDSSVSSNN
2230 2240 2250 2260 2270 2280
VLLNSQADDR VVINKPESAG FRDVGSEEIQ DAENSAKTLK EIRTLLMEAE NMALKRCNFP
2290 2300 2310 2320 2330 2340
APLARFRDIS DISFIQSKKV VCFKEPSSTG VSNGDLLHRQ PFTEESPSSR CIQKDIGTQT
2350 2360 2370 2380 2390 2400
NLKCRRGIEN WEFISSTTVR SPLQEAESKV SMALEETLRQ YQAAKSVMRS EPEGCSGTIG
2410 2420 2430 2440 2450 2460
NKIIIPMMTV IKSDSSSDAS DGNGSCSWDS NLPESLESVS DVLLNFFPYV SPKTSITDSR
2470 2480 2490 2500 2510 2520
EEEGVSESED GGGSSVDSLA AHVKNLLQCE SSLNHAKEIL RNAEEEESRV RAHAWNMKFN
2530 2540 2550 2560 2570 2580
LAHDCGYSIS ELNEDDRRKV EEIKAELFGH GRTTDLSKGL QSPRGMGCKP EAVCSHIIIE
2590 2600 2610 2620 2630 2640
SHEKGCFRTL TSEHPQLDRH PCAFRSAGPS EMTRGRQNPS SCRAKHVNLS ASLDQNNSHF
2650 2660 2670 2680 2690 2700
KVWNSLQLKS HSPFQNFIPD EFKISKGLRM PFDEKMDPWL SELVEPAFVP PKEVDFHSSS
2710 2720 2730 2740 2750 2760
QMPSPEPMKK FTTSITFSSH RHSKCISNSS VVKVGVTEGS QCTGASVGVF NSHFTEEQNP
2770 2780 2790 2800 2810 2820
PRDLKQKTSS PSSFKMHSNS QDKEVTILAE GRRQSQKLPV DFERSFQEEK PLERSDFTGS
2830 2840 2850 2860 2870 2880
HSEPSTRANC SNFKEIQISD NHTLISMGRP SSTLGVNRSS SRLGVKEKNV TITPDLPSCI
2890 2900 2910 2920 2930 2940
FLEQRELFEQ SKAPRADDHV RKHHSPSPQH QDYVAPDLPS CIFLEQRELF EQCKAPYVDH
2950 2960 2970 2980 2990 3000
QMRENHSPLP QGQDSIASDL PSPISLEQCQ SKAPGVDDQM NKHHFPLPQG QDCVVEKNNQ
3010 3020 3030 3040 3050 3060
HKPKSHISNI NVEAKFNTVV SQSAPNHCTL AASASTPPSN RKALSCVHIT LCPKTSSKLD
3070 3080 3090 3100 3110 3120
SGTLDERFHS LDAASKARMN SEFNFDLHTV SSRSLEPTSK LLTSKPVAQD QESLGFLGPK
3130 3140 3150 3160 3170 3180
SSLDFQVVQP SLPDSNTITQ DLKTIPSQNS QIVTSRQIQV NISDFEGHSN PEGTPVFADR
3190 3200 3210 3220 3230 3240
LPEKMKTPLS AFSEKLSSDA VTQITTESPE KTLFSSEIFI NAEDRGHEII EPGNQKLRKA
3250 3260 3270 3280 3290 3300
PVKFASSSSV QQVTFSRGTD GQPLLLPYKP SGSTKMYYVP QLRQIPPSPD SKSDTTVESS
3310 3320 3330 3340 3350 3360
HSGSNDAIAP DFPAQVLGTR DDDLSATVNI KHKEGIYSKR VVTKASLPVG EKPLQNENAD
3370 3380 3390 3400 3410 3420
ASVQVLITGD ENLSDKKQQE IHSTRAVTEA AQAKEKESLQ KDTADSSAAA AAEHSAQVGD
3430 3440 3450 3460 3470 3480
PEMKNLPDTK AITQKEEIHR KKTVPEEAWP NNKESLQINI EESECHSEFE NTTRSVFRSA
3490 3500 3510 3520 3530 3540
KFYIHHPVHL PSDQDICHES LGKSVFMRHS WKDFFQHHPD KHREHMCLPL PYQNMDKTKT
3550 3560 3570 3580 3590 3600
DYTRIKSLSI NVNLGNKEVM DTTKSQVRDY PKHNGQISDP QRDQKVTPEQ TTQHTVSLNE
3610 3620 3630 3640 3650 3660
LWNKYRERQR QQRQPELGDR KELSLVDRLD RLAKILQNPI THSLQVSEST HDDSRGERSV
3670 3680 3690 3700 3710 3720
KEWSGRQQQR NKLQKKKRFK SLEKSHKNTG ELKKSKVLSH HRAGRSNQIK IEQIKFDKYI
3730 3740 3750 3760 3770 3780
LSKQPGFNYI SNTSSDCRPS EESELLTDTT TNILSGTTST VESDILTQTD REVALHERSS
3790 3800 3810 3820 3830 3840
SVSTIDTARL IQAFGHERVC LSPRRIKLYS SITNQQRRYL EKRSKHSKKV LNTGHPLVTS
3850 3860 3870 3880 3890 3900
EHTRRRHIQV ANHVISSDSI SSSASSFLSS NSTFCNKQNV HMLNKGIQAG NLEIVNGAKK
3910 3920 3930 3940 3950 3960
HTRDVGITFP TPSSSEAKLE ENSDVTSWSE EKREEKMLFT GYPEDRKLKK NKKNSHEGVS
3970 3980 3990 4000 4010 4020
WFVPVENVES RSKKENVPNT CGPGISWFEP ITKTRPWREP LREQNCQGQH LDGRGYLAGP
4030 4040 4050 4060 4070 4080
GREAGRDLLR PFVRATLQES LQFHRPDFIS RSGERIKRLK LIVQERKLQS MLQTERDALF
4090 4100 4110 4120 4130 4140
NIDRERQGHQ NRMCPLPKRV FLAIQKNKPI SKKEMIQRSK RIYEQLPEVQ KKREEEKRKS
4150 4160
EYKSYRLRAQ LYKKRVTNQL LGRKVPWD
Isoforms
- Isoform 2 of Alstrom syndrome protein 1 - Isoform 3 of Alstrom syndrome protein 1 - Isoform 2 of Alstrom syndrome protein 1 - Isoform 3 of Alstrom syndrome protein 1Sequence View
10 20 30 40 50 60
MEPEDLPWPG ELEEEEEEEE EEEEEEEEAA AAAAANVDDV VVVEEVEEEA GRELDSDSHY
70 80 90 100 110 120
GPQHLESIDD EEDEEAKAWL QAHPGRILPP LSPPQHRYSE GERTSLEKIV PLTCHVWQQI
130 140 150 160 170 180
VYQGNSRTQI SDTNVVCLET TAQRGSGDDQ KTESWHCLPQ EMDSSQTLDT SQTRFNVRTE
190 200 210 220 230 240
DTEVTDFPSL EEGILTQSEN QVKEPNRDLF CSPLLVIQDS FASPDLPLLT CLTQDQEFAP
250 260 270 280 290 300
DSLFHQSELS FAPLRGIPDK SEDTEWSSRP SEVSEALFQA TAEVASDLAS SRFSVSQHPL
310 320 330 340 350 360
IGSTAVGSQC PFLPSEQGNN EETISSVDEL KIPKDCDRYD DLCSYMSWKT RKDTQWPENN
370 380 390 400 410 420
LADKDQVSVA TSFDITDENI ATKRSDHFDA ARSYGQYWTQ EDSSKQAETY LTKGLQGKVE
430 440 450 460 470 480
SDVITLDGLN ENAVVCSERV AELQRKPTRE SEYHSSDLRM LRMSPDTVPK APKHLKAGDT
490 500 510 520 530 540
SKGGIAKVTQ SNLKSGITTT PVDSDIGSHL SLSLEDLSQL AVSSPLETTT GQHTDTLNQK
550 560 570 580 590 600
TLADTHLTEE TLKVTAIPEP ADQKTATPTV LSSSHSHRGK PSIFYQQGLP DSHLTEEALK
610 620 630 640 650 660
VSAAPGLADQ TTGMSTLTST SYSHREKPGT FYQQELPESN LTEEPLEVSA APGPVEQKTG
670 680 690 700 710 720
IPTVSSTSHS HVEDLLFFYR QTLPDGHLTD QALKVSAVSG PADQKTGTAT VLSTPHSHRE
730 740 750 760 770 780
KPGIFYQQEF ADSHQTEETL TKVSATPGPA DQKTEIPAVQ SSSYSQREKP SILYPQDLAD
790 800 810 820 830 840
SHLPEEGLKV SAVAGPADQK TGLPTVPSSA YSHREKLLVF YQQALLDSHL PEEALKVSAV
850 860 870 880 890 900
SGPADGKTGT PAVTSTSSAS SSLGEKPSAF YQQTLPNSHL TEEALKVSIV PGPGDQKTGI
910 920 930 940 950 960
PSAPSSFYSH REKPIIFSQQ TLPDFLFPEE ALKVSAVSVL AAQKTGTPTV SSNSHSHSEK
970 980 990 1000 1010 1020
SSVFYQQELP DSDLPRESLK MSAIPGLTDQ KTVPTPTVPS GSFSHREKPS IFYQQEWPDS
1030 1040 1050 1060 1070 1080
YATEKALKVS TGPGPADQKT EIPAVQSSSY PQREKPSVLY PQVLSDSHLP EESLKVSAFP
1090 1100 1110 1120 1130 1140
GPADQMTDTP AVPSTFYSQR EKPGIFYQQT LPESHLPKEA LKISVAPGLA DQKTGTPTVT
1150 1160 1170 1180 1190 1200
STSYSQHREK PSIFHQQALP GTHIPEEAQK VSAVTGPGNQ KTWIPRVLST FYSQREKPGI
1210 1220 1230 1240 1250 1260
FYQQTLPGSH IPEEAQKVSP VLGPADQKTG TPTPTSASYS HTEKPGIFYQ QVLPDNHPTE
1270 1280 1290 1300 1310 1320
EALKISVASE PVDQTTGTPA VTSTSYSQYR EKPSIFYQQS LPSSHLTEEA KNVSAVPGPA
1330 1340 1350 1360 1370 1380
DQKTVIPILP STFYSHTEKP GVFYQQVLPH SHPTEEALKI SVASEPVDQT TGTPTVTSTS
1390 1400 1410 1420 1430 1440
YSQHTEKPSI FYQQSLPGSH LTEEAKNVSA VPGPGDRKTG IPTLPSTFYS HTEKPGSFYQ
1450 1460 1470 1480 1490 1500
QVLPHSHLPE EALEVSVAPG PVDQTIGTPT VTSPSSSFGE KPIVIYKQAF PEGHLPEESL
1510 1520 1530 1540 1550 1560
KVSVAPGPVG QTTGAPTITS PSYSQHRAKS GSFYQLALLG SQIPEEALRV SSAPGPADQT
1570 1580 1590 1600 1610 1620
TGIPTITSTS YSFGEKPIVN YKQAFPDGHL PEEALKVSIV SGPTEKKTDI PAGPLGSSAL
1630 1640 1650 1660 1670 1680
GEKPITFYRQ ALLDSPLNKE VVKVSAAPGP ADQKTETLPV HSTSYSNRGK PVIFYQQTLS
1690 1700 1710 1720 1730 1740
DSHLPEEALK VPPVPGPDAQ KTETPSVSSS LYSYREKPIV FYQQALPDSE LTQEALKVSA
1750 1760 1770 1780 1790 1800
VPQPADQKTG LSTVTSSFYS HTEKPNISYQ QELPDSHLTE EALKVSNVPG PADQKTGVST
1810 1820 1830 1840 1850 1860
VTSTSYSHRE KPIVSYQREL PHFTEAGLKI LRVPGPADQK TGINILPSNS YPQREHSVIS
1870 1880 1890 1900 1910 1920
YEQELPDLTE VTLKAIGVPG PADQKTGIQI ASSSSYSNRE KASIFHQQEL PDVTEEALNV
1930 1940 1950 1960 1970 1980
FVVPGQGDRK TEIPTVPLSY YSRREKPSVI SQQELPDSHL TEEALKVSPV SIPAEQKTGI
1990 2000 2010 2020 2030 2040
PIGLSSSYSH SHKEKLKIST VHIPDDQKTE FPAATLSSYS QIEKPKISTV IGPNDQKTPS
2050 2060 2070 2080 2090 2100
QTAFHSSYSQ TVKPNILFQQ QLPDRDQSKG ILKISAVPEL TDVNTGKPVS LSSSYFHREK
2110 2120 2130 2140 2150 2160
SNIFSPQELP GSHVTEDVLK VSTIPGPAGQ KTVLPTALPS SFSHREKPDI FYQKDLPDRH
2170 2180 2190 2200 2210 2220
LTEDALKISS ALGQADQITG LQTVPSGTYS HGENHKLVSE HVQRLIDNLN SSDSSVSSNN
2230 2240 2250 2260 2270 2280
VLLNSQADDR VVINKPESAG FRDVGSEEIQ DAENSAKTLK EIRTLLMEAE NMALKRCNFP
2290 2300 2310 2320 2330 2340
APLARFRDIS DISFIQSKKV VCFKEPSSTG VSNGDLLHRQ PFTEESPSSR CIQKDIGTQT
2350 2360 2370 2380 2390 2400
NLKCRRGIEN WEFISSTTVR SPLQEAESKV SMALEETLRQ YQAAKSVMRS EPEGCSGTIG
2410 2420 2430 2440 2450 2460
NKIIIPMMTV IKSDSSSDAS DGNGSCSWDS NLPESLESVS DVLLNFFPYV SPKTSITDSR
2470 2480 2490 2500 2510 2520
EEEGVSESED GGGSSVDSLA AHVKNLLQCE SSLNHAKEIL RNAEEEESRV RAHAWNMKFN
2530 2540 2550 2560 2570 2580
LAHDCGYSIS ELNEDDRRKV EEIKAELFGH GRTTDLSKGL QSPRGMGCKP EAVCSHIIIE
2590 2600 2610 2620 2630 2640
SHEKGCFRTL TSEHPQLDRH PCAFRSAGPS EMTRGRQNPS SCRAKHVNLS ASLDQNNSHF
2650 2660 2670 2680 2690 2700
KVWNSLQLKS HSPFQNFIPD EFKISKGLRM PFDEKMDPWL SELVEPAFVP PKEVDFHSSS
2710 2720 2730 2740 2750 2760
QMPSPEPMKK FTTSITFSSH RHSKCISNSS VVKVGVTEGS QCTGASVGVF NSHFTEEQNP
2770 2780 2790 2800 2810 2820
PRDLKQKTSS PSSFKMHSNS QDKEVTILAE GRRQSQKLPV DFERSFQEEK PLERSDFTGS
2830 2840 2850 2860 2870 2880
HSEPSTRANC SNFKEIQISD NHTLISMGRP SSTLGVNRSS SRLGVKEKNV TITPDLPSCI
2890 2900 2910 2920 2930 2940
FLEQRELFEQ SKAPRADDHV RKHHSPSPQH QDYVAPDLPS CIFLEQRELF EQCKAPYVDH
2950 2960 2970 2980 2990 3000
QMRENHSPLP QGQDSIASDL PSPISLEQCQ SKAPGVDDQM NKHHFPLPQG QDCVVEKNNQ
3010 3020 3030 3040 3050 3060
HKPKSHISNI NVEAKFNTVV SQSAPNHCTL AASASTPPSN RKALSCVHIT LCPKTSSKLD
3070 3080 3090 3100 3110 3120
SGTLDERFHS LDAASKARMN SEFNFDLHTV SSRSLEPTSK LLTSKPVAQD QESLGFLGPK
3130 3140 3150 3160 3170 3180
SSLDFQVVQP SLPDSNTITQ DLKTIPSQNS QIVTSRQIQV NISDFEGHSN PEGTPVFADR
3190 3200 3210 3220 3230 3240
LPEKMKTPLS AFSEKLSSDA VTQITTESPE KTLFSSEIFI NAEDRGHEII EPGNQKLRKA
3250 3260 3270 3280 3290 3300
PVKFASSSSV QQVTFSRGTD GQPLLLPYKP SGSTKMYYVP QLRQIPPSPD SKSDTTVESS
3310 3320 3330 3340 3350 3360
HSGSNDAIAP DFPAQVLGTR DDDLSATVNI KHKEGIYSKR VVTKASLPVG EKPLQNENAD
3370 3380 3390 3400 3410 3420
ASVQVLITGD ENLSDKKQQE IHSTRAVTEA AQAKEKESLQ KDTADSSAAA AAEHSAQVGD
3430 3440 3450 3460 3470 3480
PEMKNLPDTK AITQKEEIHR KKTVPEEAWP NNKESLQINI EESECHSEFE NTTRSVFRSA
3490 3500 3510 3520 3530 3540
KFYIHHPVHL PSDQDICHES LGKSVFMRHS WKDFFQHHPD KHREHMCLPL PYQNMDKTKT
3550 3560 3570 3580 3590 3600
DYTRIKSLSI NVNLGNKEVM DTTKSQVRDY PKHNGQISDP QRDQKVTPEQ TTQHTVSLNE
3610 3620 3630 3640 3650 3660
LWNKYRERQR QQRQPELGDR KELSLVDRLD RLAKILQNPI THSLQVSEST HDDSRGERSV
3670 3680 3690 3700 3710 3720
KEWSGRQQQR NKLQKKKRFK SLEKSHKNTG ELKKSKVLSH HRAGRSNQIK IEQIKFDKYI
3730 3740 3750 3760 3770 3780
LSKQPGFNYI SNTSSDCRPS EESELLTDTT TNILSGTTST VESDILTQTD REVALHERSS
3790 3800 3810 3820 3830 3840
SVSTIDTARL IQAFGHERVC LSPRRIKLYS SITNQQRRYL EKRSKHSKKV LNTGHPLVTS
3850 3860 3870 3880 3890 3900
EHTRRRHIQV ANHVISSDSI SSSASSFLSS NSTFCNKQNV HMLNKGIQAG NLEIVNGAKK
3910 3920 3930 3940 3950 3960
HTRDVGITFP TPSSSEAKLE ENSDVTSWSE EKREEKMLFT GYPEDRKLKK NKKNSHEGVS
3970 3980 3990 4000 4010 4020
WFVPVENVES RSKKENVPNT CGPGISWFEP ITKTRPWREP LREQNCQGQH LDGRGYLAGP
4030 4040 4050 4060 4070 4080
GREAGRDLLR PFVRATLQES LQFHRPDFIS RSGERIKRLK LIVQERKLQS MLQTERDALF
4090 4100 4110 4120 4130 4140
NIDRERQGHQ NRMCPLPKRV FLAIQKNKPI SKKEMIQRSK RIYEQLPEVQ KKREEEKRKS
4150 4160
EYKSYRLRAQ LYKKRVTNQL LGRKVPWD
10 20 30 40 50 60
MEPEDLPWPG ELEEEEEEEE EEEEEEEEAA AAAAANVDDV VVVEEVEEEA GRELDSDSHY
70 80 90 100 110 120
GPQHLESIDD EEDEEAKAWL QAHPGRILPP LSPPQHRYSE GERTSLEKIV PLTCHVWQQI
130 140 150 160 170 180
VYQGNSRTQI SDTNVVCLET TAQRGSGDDQ KTESWHCLPQ EMDSSQTLDT SQTRFNVRTE
190 200 210 220 230 240
DTEVTDFPSL EEGILTQSEN QVKEPNRDLF CSPLLVIQDS FASPDLPLLT CLTQDQEFAP
250 260 270 280 290 300
DSLFHQSELS FAPLRGIPDK SEDTEWSSRP SEVSEALFQA TAEVASDLAS SRFSVSQHPL
310 320 330 340 350 360
IGSTAVGSQC PFLPSEQGNN EETISSVDEL KIPKDCDRYD DLCSYMSWKT RKDTQWPENN
370 380 390 400 410 420
LADKDQVSVA TSFDITDENI ATKRSDHFDA ARSYGQYWTQ EDSSKQAETY LTKGLQGKVE
430 440 450 460 470 480
SDVITLDGLN ENAVVCSERV AELQRKPTRE SEYHSSDLRM LRMSPDTVPK APKHLKAGDT
490 500 510 520 530 540
SKGGIAKVTQ SNLKSGITTT PVDSDIGSHL SLSLEDLSQL AVSSPLETTT GQHTDTLNQK
550 560 570 580 590 600
TLADTHLTEE TLKVTAIPEP ADQKTATPTV LSSSHSHRGK PSIFYQQGLP DSHLTEEALK
610 620 630 640 650 660
VSAAPGLADQ TTGMSTLTST SYSHREKPGT FYQQELPESN LTEEPLEVSA APGPVEQKTG
670 680 690 700 710 720
IPTVSSTSHS HVEDLLFFYR QTLPDGHLTD QALKVSAVSG PADQKTGTAT VLSTPHSHRE
730 740 750 760 770 780
KPGIFYQQEF ADSHQTEETL TKVSATPGPA DQKTEIPAVQ SSSYSQREKP SILYPQDLAD
790 800 810 820 830 840
SHLPEEGLKV SAVAGPADQK TGLPTVPSSA YSHREKLLVF YQQALLDSHL PEEALKVSAV
850 860 870 880 890 900
SGPADGKTGT PAVTSTSSAS SSLGEKPSAF YQQTLPNSHL TEEALKVSIV PGPGDQKTGI
910 920 930 940 950 960
PSAPSSFYSH REKPIIFSQQ TLPDFLFPEE ALKVSAVSVL AAQKTGTPTV SSNSHSHSEK
970 980 990 1000 1010 1020
SSVFYQQELP DSDLPRESLK MSAIPGLTDQ KTVPTPTVPS GSFSHREKPS IFYQQEWPDS
1030 1040 1050 1060 1070 1080
YATEKALKVS TGPGPADQKT EIPAVQSSSY PQREKPSVLY PQVLSDSHLP EESLKVSAFP
1090 1100 1110 1120 1130 1140
GPADQMTDTP AVPSTFYSQR EKPGIFYQQT LPESHLPKEA LKISVAPGLA DQKTGTPTVT
1150 1160 1170 1180 1190 1200
STSYSQHREK PSIFHQQALP GTHIPEEAQK VSAVTGPGNQ KTWIPRVLST FYSQREKPGI
1210 1220 1230 1240 1250 1260
FYQQTLPGSH IPEEAQKVSP VLGPADQKTG TPTPTSASYS HTEKPGIFYQ QVLPDNHPTE
1270 1280 1290 1300 1310 1320
EALKISVASE PVDQTTGTPA VTSTSYSQYR EKPSIFYQQS LPSSHLTEEA KNVSAVPGPA
1330 1340 1350 1360 1370 1380
DQKTVIPILP STFYSHTEKP GVFYQQVLPH SHPTEEALKI SVASEPVDQT TGTPTVTSTS
1390 1400 1410 1420 1430 1440
YSQHTEKPSI FYQQSLPGSH LTEEAKNVSA VPGPGDRKTG IPTLPSTFYS HTEKPGSFYQ
1450 1460 1470 1480 1490 1500
QVLPHSHLPE EALEVSVAPG PVDQTIGTPT VTSPSSSFGE KPIVIYKQAF PEGHLPEESL
1510 1520 1530 1540 1550 1560
KVSVAPGPVG QTTGAPTITS PSYSQHRAKS GSFYQLALLG SQIPEEALRV SSAPGPADQT
1570 1580 1590 1600 1610 1620
TGIPTITSTS YSFGEKPIVN YKQAFPDGHL PEEALKVSIV SGPTEKKTDI PAGPLGSSAL
1630 1640 1650 1660 1670 1680
GEKPITFYRQ ALLDSPLNKE VVKVSAAPGP ADQKTETLPV HSTSYSNRGK PVIFYQQTLS
1690 1700 1710 1720 1730 1740
DSHLPEEALK VPPVPGPDAQ KTETPSVSSS LYSYREKPIV FYQQALPDSE LTQEALKVSA
1750 1760 1770 1780 1790 1800
VPQPADQKTG LSTVTSSFYS HTEKPNISYQ QELPDSHLTE EALKVSNVPG PADQKTGVST
1810 1820 1830 1840 1850 1860
VTSTSYSHRE KPIVSYQREL PHFTEAGLKI LRVPGPADQK TGINILPSNS YPQREHSVIS
1870 1880 1890 1900 1910 1920
YEQELPDLTE VTLKAIGVPG PADQKTGIQI ASSSSYSNRE KASIFHQQEL PDVTEEALNV
1930 1940 1950 1960 1970 1980
FVVPGQGDRK TEIPTVPLSY YSRREKPSVI SQQELPDSHL TEEALKVSPV SIPAEQKTGI
1990 2000 2010 2020 2030 2040
PIGLSSSYSH SHKEKLKIST VHIPDDQKTE FPAATLSSYS QIEKPKISTV IGPNDQKTPS
2050 2060 2070 2080 2090 2100
QTAFHSSYSQ TVKPNILFQQ QLPDRDQSKG ILKISAVPEL TDVNTGKPVS LSSSYFHREK
2110 2120 2130 2140 2150 2160
SNIFSPQELP GSHVTEDVLK VSTIPGPAGQ KTVLPTALPS SFSHREKPDI FYQKDLPDRH
2170 2180 2190 2200 2210 2220
LTEDALKISS ALGQADQITG LQTVPSGTYS HGENHKLVSE HVQRLIDNLN SSDSSVSSNN
2230 2240 2250 2260 2270 2280
VLLNSQADDR VVINKPESAG FRDVGSEEIQ DAENSAKTLK EIRTLLMEAE NMALKRCNFP
2290 2300 2310 2320 2330 2340
APLARFRDIS DISFIQSKKV VCFKEPSSTG VSNGDLLHRQ PFTEESPSSR CIQKDIGTQT
2350 2360 2370 2380 2390 2400
NLKCRRGIEN WEFISSTTVR SPLQEAESKV SMALEETLRQ YQAAKSVMRS EPEGCSGTIG
2410 2420 2430 2440 2450 2460
NKIIIPMMTV IKSDSSSDAS DGNGSCSWDS NLPESLESVS DVLLNFFPYV SPKTSITDSR
2470 2480 2490 2500 2510 2520
EEEGVSESED GGGSSVDSLA AHVKNLLQCE SSLNHAKEIL RNAEEEESRV RAHAWNMKFN
2530 2540 2550 2560 2570 2580
LAHDCGYSIS ELNEDDRRKV EEIKAELFGH GRTTDLSKGL QSPRGMGCKP EAVCSHIIIE
2590 2600 2610 2620 2630 2640
SHEKGCFRTL TSEHPQLDRH PCAFRSAGPS EMTRGRQNPS SCRAKHVNLS ASLDQNNSHF
2650 2660 2670 2680 2690 2700
KVWNSLQLKS HSPFQNFIPD EFKISKGLRM PFDEKMDPWL SELVEPAFVP PKEVDFHSSS
2710 2720 2730 2740 2750 2760
QMPSPEPMKK FTTSITFSSH RHSKCISNSS VVKVGVTEGS QCTGASVGVF NSHFTEEQNP
2770 2780 2790 2800 2810 2820
PRDLKQKTSS PSSFKMHSNS QDKEVTILAE GRRQSQKLPV DFERSFQEEK PLERSDFTGS
2830 2840 2850 2860 2870 2880
HSEPSTRANC SNFKEIQISD NHTLISMGRP SSTLGVNRSS SRLGVKEKNV TITPDLPSCI
2890 2900 2910 2920 2930 2940
FLEQRELFEQ SKAPRADDHV RKHHSPSPQH QDYVAPDLPS CIFLEQRELF EQCKAPYVDH
2950 2960 2970 2980 2990 3000
QMRENHSPLP QGQDSIASDL PSPISLEQCQ SKAPGVDDQM NKHHFPLPQG QDCVVEKNNQ
3010 3020 3030 3040 3050 3060
HKPKSHISNI NVEAKFNTVV SQSAPNHCTL AASASTPPSN RKALSCVHIT LCPKTSSKLD
3070 3080 3090 3100 3110 3120
SGTLDERFHS LDAASKARMN SEFNFDLHTV SSRSLEPTSK LLTSKPVAQD QESLGFLGPK
3130 3140 3150 3160 3170 3180
SSLDFQVVQP SLPDSNTITQ DLKTIPSQNS QIVTSRQIQV NISDFEGHSN PEGTPVFADR
3190 3200 3210 3220 3230 3240
LPEKMKTPLS AFSEKLSSDA VTQITTESPE KTLFSSEIFI NAEDRGHEII EPGNQKLRKA
3250 3260 3270 3280 3290 3300
PVKFASSSSV QQVTFSRGTD GQPLLLPYKP SGSTKMYYVP QLRQIPPSPD SKSDTTVESS
3310 3320 3330 3340 3350 3360
HSGSNDAIAP DFPAQVLGTR DDDLSATVNI KHKEGIYSKR VVTKASLPVG EKPLQNENAD
3370 3380 3390 3400 3410 3420
ASVQVLITGD ENLSDKKQQE IHSTRAVTEA AQAKEKESLQ KDTADSSAAA AAEHSAQVGD
3430 3440 3450 3460 3470 3480
PEMKNLPDTK AITQKEEIHR KKTVPEEAWP NNKESLQINI EESECHSEFE NTTRSVFRSA
3490 3500 3510 3520 3530 3540
KFYIHHPVHL PSDQDICHES LGKSVFMRHS WKDFFQHHPD KHREHMCLPL PYQNMDKTKT
3550 3560 3570 3580 3590 3600
DYTRIKSLSI NVNLGNKEVM DTTKSQVRDY PKHNGQISDP QRDQKVTPEQ TTQHTVSLNE
3610 3620 3630 3640 3650 3660
LWNKYRERQR QQRQPELGDR KELSLVDRLD RLAKILQNPI THSLQVSEST HDDSRGERSV
3670 3680 3690 3700 3710 3720
KEWSGRQQQR NKLQKKKRFK SLEKSHKNTG ELKKSKVLSH HRAGRSNQIK IEQIKFDKYI
3730 3740 3750 3760 3770 3780
LSKQPGFNYI SNTSSDCRPS EESELLTDTT TNILSGTTST VESDILTQTD REVALHERSS
3790 3800 3810 3820 3830 3840
SVSTIDTARL IQAFGHERVC LSPRRIKLYS SITNQQRRYL EKRSKHSKKV LNTGHPLVTS
3850 3860 3870 3880 3890 3900
EHTRRRHIQV ANHVISSDSI SSSASSFLSS NSTFCNKQNV HMLNKGIQAG NLEIVNGAKK
3910 3920 3930 3940 3950 3960
HTRDVGITFP TPSSSEAKLE ENSDVTSWSE EKREEKMLFT GYPEDRKLKK NKKNSHEGVS
3970 3980 3990 4000 4010 4020
WFVPVENVES RSKKENVPNT CGPGISWFEP ITKTRPWREP LREQNCQGQH LDGRGYLAGP
4030 4040 4050 4060 4070 4080
GREAGRDLLR PFVRATLQES LQFHRPDFIS RSGERIKRLK LIVQERKLQS MLQTERDALF
4090 4100 4110 4120 4130 4140
NIDRERQGHQ NRMCPLPKRV FLAIQKNKPI SKKEMIQRSK RIYEQLPEVQ KKREEEKRKS
4150 4160
EYKSYRLRAQ LYKKRVTNQL LGRKVPWD
10 20 30 40 50 60
MEPEDLPWPG ELEEEEEEEE EEEEEEEEAA AAAAANVDDV VVVEEVEEEA GRELDSDSHY
70 80 90 100 110 120
GPQHLESIDD EEDEEAKAWL QAHPGRILPP LSPPQHRYSE GERTSLEKIV PLTCHVWQQI
130 140 150 160 170 180
VYQGNSRTQI SDTNVVCLET TAQRGSGDDQ KTESWHCLPQ EMDSSQTLDT SQTRFNVRTE
190 200 210 220 230 240
DTEVTDFPSL EEGILTQSEN QVKEPNRDLF CSPLLVIQDS FASPDLPLLT CLTQDQEFAP
250 260 270 280 290 300
DSLFHQSELS FAPLRGIPDK SEDTEWSSRP SEVSEALFQA TAEVASDLAS SRFSVSQHPL
310 320 330 340 350 360
IGSTAVGSQC PFLPSEQGNN EETISSVDEL KIPKDCDRYD DLCSYMSWKT RKDTQWPENN
370 380 390 400 410 420
LADKDQVSVA TSFDITDENI ATKRSDHFDA ARSYGQYWTQ EDSSKQAETY LTKGLQGKVE
430 440 450 460 470 480
SDVITLDGLN ENAVVCSERV AELQRKPTRE SEYHSSDLRM LRMSPDTVPK APKHLKAGDT
490 500 510 520 530 540
SKGGIAKVTQ SNLKSGITTT PVDSDIGSHL SLSLEDLSQL AVSSPLETTT GQHTDTLNQK
550 560 570 580 590 600
TLADTHLTEE TLKVTAIPEP ADQKTATPTV LSSSHSHRGK PSIFYQQGLP DSHLTEEALK
610 620 630 640 650 660
VSAAPGLADQ TTGMSTLTST SYSHREKPGT FYQQELPESN LTEEPLEVSA APGPVEQKTG
670 680 690 700 710 720
IPTVSSTSHS HVEDLLFFYR QTLPDGHLTD QALKVSAVSG PADQKTGTAT VLSTPHSHRE
730 740 750 760 770 780
KPGIFYQQEF ADSHQTEETL TKVSATPGPA DQKTEIPAVQ SSSYSQREKP SILYPQDLAD
790 800 810 820 830 840
SHLPEEGLKV SAVAGPADQK TGLPTVPSSA YSHREKLLVF YQQALLDSHL PEEALKVSAV
850 860 870 880 890 900
SGPADGKTGT PAVTSTSSAS SSLGEKPSAF YQQTLPNSHL TEEALKVSIV PGPGDQKTGI
910 920 930 940 950 960
PSAPSSFYSH REKPIIFSQQ TLPDFLFPEE ALKVSAVSVL AAQKTGTPTV SSNSHSHSEK
970 980 990 1000 1010 1020
SSVFYQQELP DSDLPRESLK MSAIPGLTDQ KTVPTPTVPS GSFSHREKPS IFYQQEWPDS
1030 1040 1050 1060 1070 1080
YATEKALKVS TGPGPADQKT EIPAVQSSSY PQREKPSVLY PQVLSDSHLP EESLKVSAFP
1090 1100 1110 1120 1130 1140
GPADQMTDTP AVPSTFYSQR EKPGIFYQQT LPESHLPKEA LKISVAPGLA DQKTGTPTVT
1150 1160 1170 1180 1190 1200
STSYSQHREK PSIFHQQALP GTHIPEEAQK VSAVTGPGNQ KTWIPRVLST FYSQREKPGI
1210 1220 1230 1240 1250 1260
FYQQTLPGSH IPEEAQKVSP VLGPADQKTG TPTPTSASYS HTEKPGIFYQ QVLPDNHPTE
1270 1280 1290 1300 1310 1320
EALKISVASE PVDQTTGTPA VTSTSYSQYR EKPSIFYQQS LPSSHLTEEA KNVSAVPGPA
1330 1340 1350 1360 1370 1380
DQKTVIPILP STFYSHTEKP GVFYQQVLPH SHPTEEALKI SVASEPVDQT TGTPTVTSTS
1390 1400 1410 1420 1430 1440
YSQHTEKPSI FYQQSLPGSH LTEEAKNVSA VPGPGDRKTG IPTLPSTFYS HTEKPGSFYQ
1450 1460 1470 1480 1490 1500
QVLPHSHLPE EALEVSVAPG PVDQTIGTPT VTSPSSSFGE KPIVIYKQAF PEGHLPEESL
1510 1520 1530 1540 1550 1560
KVSVAPGPVG QTTGAPTITS PSYSQHRAKS GSFYQLALLG SQIPEEALRV SSAPGPADQT
1570 1580 1590 1600 1610 1620
TGIPTITSTS YSFGEKPIVN YKQAFPDGHL PEEALKVSIV SGPTEKKTDI PAGPLGSSAL
1630 1640 1650 1660 1670 1680
GEKPITFYRQ ALLDSPLNKE VVKVSAAPGP ADQKTETLPV HSTSYSNRGK PVIFYQQTLS
1690 1700 1710 1720 1730 1740
DSHLPEEALK VPPVPGPDAQ KTETPSVSSS LYSYREKPIV FYQQALPDSE LTQEALKVSA
1750 1760 1770 1780 1790 1800
VPQPADQKTG LSTVTSSFYS HTEKPNISYQ QELPDSHLTE EALKVSNVPG PADQKTGVST
1810 1820 1830 1840 1850 1860
VTSTSYSHRE KPIVSYQREL PHFTEAGLKI LRVPGPADQK TGINILPSNS YPQREHSVIS
1870 1880 1890 1900 1910 1920
YEQELPDLTE VTLKAIGVPG PADQKTGIQI ASSSSYSNRE KASIFHQQEL PDVTEEALNV
1930 1940 1950 1960 1970 1980
FVVPGQGDRK TEIPTVPLSY YSRREKPSVI SQQELPDSHL TEEALKVSPV SIPAEQKTGI
1990 2000 2010 2020 2030 2040
PIGLSSSYSH SHKEKLKIST VHIPDDQKTE FPAATLSSYS QIEKPKISTV IGPNDQKTPS
2050 2060 2070 2080 2090 2100
QTAFHSSYSQ TVKPNILFQQ QLPDRDQSKG ILKISAVPEL TDVNTGKPVS LSSSYFHREK
2110 2120 2130 2140 2150 2160
SNIFSPQELP GSHVTEDVLK VSTIPGPAGQ KTVLPTALPS SFSHREKPDI FYQKDLPDRH
2170 2180 2190 2200 2210 2220
LTEDALKISS ALGQADQITG LQTVPSGTYS HGENHKLVSE HVQRLIDNLN SSDSSVSSNN
2230 2240 2250 2260 2270 2280
VLLNSQADDR VVINKPESAG FRDVGSEEIQ DAENSAKTLK EIRTLLMEAE NMALKRCNFP
2290 2300 2310 2320 2330 2340
APLARFRDIS DISFIQSKKV VCFKEPSSTG VSNGDLLHRQ PFTEESPSSR CIQKDIGTQT
2350 2360 2370 2380 2390 2400
NLKCRRGIEN WEFISSTTVR SPLQEAESKV SMALEETLRQ YQAAKSVMRS EPEGCSGTIG
2410 2420 2430 2440 2450 2460
NKIIIPMMTV IKSDSSSDAS DGNGSCSWDS NLPESLESVS DVLLNFFPYV SPKTSITDSR
2470 2480 2490 2500 2510 2520
EEEGVSESED GGGSSVDSLA AHVKNLLQCE SSLNHAKEIL RNAEEEESRV RAHAWNMKFN
2530 2540 2550 2560 2570 2580
LAHDCGYSIS ELNEDDRRKV EEIKAELFGH GRTTDLSKGL QSPRGMGCKP EAVCSHIIIE
2590 2600 2610 2620 2630 2640
SHEKGCFRTL TSEHPQLDRH PCAFRSAGPS EMTRGRQNPS SCRAKHVNLS ASLDQNNSHF
2650 2660 2670 2680 2690 2700
KVWNSLQLKS HSPFQNFIPD EFKISKGLRM PFDEKMDPWL SELVEPAFVP PKEVDFHSSS
2710 2720 2730 2740 2750 2760
QMPSPEPMKK FTTSITFSSH RHSKCISNSS VVKVGVTEGS QCTGASVGVF NSHFTEEQNP
2770 2780 2790 2800 2810 2820
PRDLKQKTSS PSSFKMHSNS QDKEVTILAE GRRQSQKLPV DFERSFQEEK PLERSDFTGS
2830 2840 2850 2860 2870 2880
HSEPSTRANC SNFKEIQISD NHTLISMGRP SSTLGVNRSS SRLGVKEKNV TITPDLPSCI
2890 2900 2910 2920 2930 2940
FLEQRELFEQ SKAPRADDHV RKHHSPSPQH QDYVAPDLPS CIFLEQRELF EQCKAPYVDH
2950 2960 2970 2980 2990 3000
QMRENHSPLP QGQDSIASDL PSPISLEQCQ SKAPGVDDQM NKHHFPLPQG QDCVVEKNNQ
3010 3020 3030 3040 3050 3060
HKPKSHISNI NVEAKFNTVV SQSAPNHCTL AASASTPPSN RKALSCVHIT LCPKTSSKLD
3070 3080 3090 3100 3110 3120
SGTLDERFHS LDAASKARMN SEFNFDLHTV SSRSLEPTSK LLTSKPVAQD QESLGFLGPK
3130 3140 3150 3160 3170 3180
SSLDFQVVQP SLPDSNTITQ DLKTIPSQNS QIVTSRQIQV NISDFEGHSN PEGTPVFADR
3190 3200 3210 3220 3230 3240
LPEKMKTPLS AFSEKLSSDA VTQITTESPE KTLFSSEIFI NAEDRGHEII EPGNQKLRKA
3250 3260 3270 3280 3290 3300
PVKFASSSSV QQVTFSRGTD GQPLLLPYKP SGSTKMYYVP QLRQIPPSPD SKSDTTVESS
3310 3320 3330 3340 3350 3360
HSGSNDAIAP DFPAQVLGTR DDDLSATVNI KHKEGIYSKR VVTKASLPVG EKPLQNENAD
3370 3380 3390 3400 3410 3420
ASVQVLITGD ENLSDKKQQE IHSTRAVTEA AQAKEKESLQ KDTADSSAAA AAEHSAQVGD
3430 3440 3450 3460 3470 3480
PEMKNLPDTK AITQKEEIHR KKTVPEEAWP NNKESLQINI EESECHSEFE NTTRSVFRSA
3490 3500 3510 3520 3530 3540
KFYIHHPVHL PSDQDICHES LGKSVFMRHS WKDFFQHHPD KHREHMCLPL PYQNMDKTKT
3550 3560 3570 3580 3590 3600
DYTRIKSLSI NVNLGNKEVM DTTKSQVRDY PKHNGQISDP QRDQKVTPEQ TTQHTVSLNE
3610 3620 3630 3640 3650 3660
LWNKYRERQR QQRQPELGDR KELSLVDRLD RLAKILQNPI THSLQVSEST HDDSRGERSV
3670 3680 3690 3700 3710 3720
KEWSGRQQQR NKLQKKKRFK SLEKSHKNTG ELKKSKVLSH HRAGRSNQIK IEQIKFDKYI
3730 3740 3750 3760 3770 3780
LSKQPGFNYI SNTSSDCRPS EESELLTDTT TNILSGTTST VESDILTQTD REVALHERSS
3790 3800 3810 3820 3830 3840
SVSTIDTARL IQAFGHERVC LSPRRIKLYS SITNQQRRYL EKRSKHSKKV LNTGHPLVTS
3850 3860 3870 3880 3890 3900
EHTRRRHIQV ANHVISSDSI SSSASSFLSS NSTFCNKQNV HMLNKGIQAG NLEIVNGAKK
3910 3920 3930 3940 3950 3960
HTRDVGITFP TPSSSEAKLE ENSDVTSWSE EKREEKMLFT GYPEDRKLKK NKKNSHEGVS
3970 3980 3990 4000 4010 4020
WFVPVENVES RSKKENVPNT CGPGISWFEP ITKTRPWREP LREQNCQGQH LDGRGYLAGP
4030 4040 4050 4060 4070 4080
GREAGRDLLR PFVRATLQES LQFHRPDFIS RSGERIKRLK LIVQERKLQS MLQTERDALF
4090 4100 4110 4120 4130 4140
NIDRERQGHQ NRMCPLPKRV FLAIQKNKPI SKKEMIQRSK RIYEQLPEVQ KKREEEKRKS
4150 4160
EYKSYRLRAQ LYKKRVTNQL LGRKVPWD
10 20 30 40 50 60
MEPEDLPWPG ELEEEEEEEE EEEEEEEEAA AAAAANVDDV VVVEEVEEEA GRELDSDSHY
70 80 90 100 110 120
GPQHLESIDD EEDEEAKAWL QAHPGRILPP LSPPQHRYSE GERTSLEKIV PLTCHVWQQI
130 140 150 160 170 180
VYQGNSRTQI SDTNVVCLET TAQRGSGDDQ KTESWHCLPQ EMDSSQTLDT SQTRFNVRTE
190 200 210 220 230 240
DTEVTDFPSL EEGILTQSEN QVKEPNRDLF CSPLLVIQDS FASPDLPLLT CLTQDQEFAP
250 260 270 280 290 300
DSLFHQSELS FAPLRGIPDK SEDTEWSSRP SEVSEALFQA TAEVASDLAS SRFSVSQHPL
310 320 330 340 350 360
IGSTAVGSQC PFLPSEQGNN EETISSVDEL KIPKDCDRYD DLCSYMSWKT RKDTQWPENN
370 380 390 400 410 420
LADKDQVSVA TSFDITDENI ATKRSDHFDA ARSYGQYWTQ EDSSKQAETY LTKGLQGKVE
430 440 450 460 470 480
SDVITLDGLN ENAVVCSERV AELQRKPTRE SEYHSSDLRM LRMSPDTVPK APKHLKAGDT
490 500 510 520 530 540
SKGGIAKVTQ SNLKSGITTT PVDSDIGSHL SLSLEDLSQL AVSSPLETTT GQHTDTLNQK
550 560 570 580 590 600
TLADTHLTEE TLKVTAIPEP ADQKTATPTV LSSSHSHRGK PSIFYQQGLP DSHLTEEALK
610 620 630 640 650 660
VSAAPGLADQ TTGMSTLTST SYSHREKPGT FYQQELPESN LTEEPLEVSA APGPVEQKTG
670 680 690 700 710 720
IPTVSSTSHS HVEDLLFFYR QTLPDGHLTD QALKVSAVSG PADQKTGTAT VLSTPHSHRE
730 740 750 760 770 780
KPGIFYQQEF ADSHQTEETL TKVSATPGPA DQKTEIPAVQ SSSYSQREKP SILYPQDLAD
790 800 810 820 830 840
SHLPEEGLKV SAVAGPADQK TGLPTVPSSA YSHREKLLVF YQQALLDSHL PEEALKVSAV
850 860 870 880 890 900
SGPADGKTGT PAVTSTSSAS SSLGEKPSAF YQQTLPNSHL TEEALKVSIV PGPGDQKTGI
910 920 930 940 950 960
PSAPSSFYSH REKPIIFSQQ TLPDFLFPEE ALKVSAVSVL AAQKTGTPTV SSNSHSHSEK
970 980 990 1000 1010 1020
SSVFYQQELP DSDLPRESLK MSAIPGLTDQ KTVPTPTVPS GSFSHREKPS IFYQQEWPDS
1030 1040 1050 1060 1070 1080
YATEKALKVS TGPGPADQKT EIPAVQSSSY PQREKPSVLY PQVLSDSHLP EESLKVSAFP
1090 1100 1110 1120 1130 1140
GPADQMTDTP AVPSTFYSQR EKPGIFYQQT LPESHLPKEA LKISVAPGLA DQKTGTPTVT
1150 1160 1170 1180 1190 1200
STSYSQHREK PSIFHQQALP GTHIPEEAQK VSAVTGPGNQ KTWIPRVLST FYSQREKPGI
1210 1220 1230 1240 1250 1260
FYQQTLPGSH IPEEAQKVSP VLGPADQKTG TPTPTSASYS HTEKPGIFYQ QVLPDNHPTE
1270 1280 1290 1300 1310 1320
EALKISVASE PVDQTTGTPA VTSTSYSQYR EKPSIFYQQS LPSSHLTEEA KNVSAVPGPA
1330 1340 1350 1360 1370 1380
DQKTVIPILP STFYSHTEKP GVFYQQVLPH SHPTEEALKI SVASEPVDQT TGTPTVTSTS
1390 1400 1410 1420 1430 1440
YSQHTEKPSI FYQQSLPGSH LTEEAKNVSA VPGPGDRKTG IPTLPSTFYS HTEKPGSFYQ
1450 1460 1470 1480 1490 1500
QVLPHSHLPE EALEVSVAPG PVDQTIGTPT VTSPSSSFGE KPIVIYKQAF PEGHLPEESL
1510 1520 1530 1540 1550 1560
KVSVAPGPVG QTTGAPTITS PSYSQHRAKS GSFYQLALLG SQIPEEALRV SSAPGPADQT
1570 1580 1590 1600 1610 1620
TGIPTITSTS YSFGEKPIVN YKQAFPDGHL PEEALKVSIV SGPTEKKTDI PAGPLGSSAL
1630 1640 1650 1660 1670 1680
GEKPITFYRQ ALLDSPLNKE VVKVSAAPGP ADQKTETLPV HSTSYSNRGK PVIFYQQTLS
1690 1700 1710 1720 1730 1740
DSHLPEEALK VPPVPGPDAQ KTETPSVSSS LYSYREKPIV FYQQALPDSE LTQEALKVSA
1750 1760 1770 1780 1790 1800
VPQPADQKTG LSTVTSSFYS HTEKPNISYQ QELPDSHLTE EALKVSNVPG PADQKTGVST
1810 1820 1830 1840 1850 1860
VTSTSYSHRE KPIVSYQREL PHFTEAGLKI LRVPGPADQK TGINILPSNS YPQREHSVIS
1870 1880 1890 1900 1910 1920
YEQELPDLTE VTLKAIGVPG PADQKTGIQI ASSSSYSNRE KASIFHQQEL PDVTEEALNV
1930 1940 1950 1960 1970 1980
FVVPGQGDRK TEIPTVPLSY YSRREKPSVI SQQELPDSHL TEEALKVSPV SIPAEQKTGI
1990 2000 2010 2020 2030 2040
PIGLSSSYSH SHKEKLKIST VHIPDDQKTE FPAATLSSYS QIEKPKISTV IGPNDQKTPS
2050 2060 2070 2080 2090 2100
QTAFHSSYSQ TVKPNILFQQ QLPDRDQSKG ILKISAVPEL TDVNTGKPVS LSSSYFHREK
2110 2120 2130 2140 2150 2160
SNIFSPQELP GSHVTEDVLK VSTIPGPAGQ KTVLPTALPS SFSHREKPDI FYQKDLPDRH
2170 2180 2190 2200 2210 2220
LTEDALKISS ALGQADQITG LQTVPSGTYS HGENHKLVSE HVQRLIDNLN SSDSSVSSNN
2230 2240 2250 2260 2270 2280
VLLNSQADDR VVINKPESAG FRDVGSEEIQ DAENSAKTLK EIRTLLMEAE NMALKRCNFP
2290 2300 2310 2320 2330 2340
APLARFRDIS DISFIQSKKV VCFKEPSSTG VSNGDLLHRQ PFTEESPSSR CIQKDIGTQT
2350 2360 2370 2380 2390 2400
NLKCRRGIEN WEFISSTTVR SPLQEAESKV SMALEETLRQ YQAAKSVMRS EPEGCSGTIG
2410 2420 2430 2440 2450 2460
NKIIIPMMTV IKSDSSSDAS DGNGSCSWDS NLPESLESVS DVLLNFFPYV SPKTSITDSR
2470 2480 2490 2500 2510 2520
EEEGVSESED GGGSSVDSLA AHVKNLLQCE SSLNHAKEIL RNAEEEESRV RAHAWNMKFN
2530 2540 2550 2560 2570 2580
LAHDCGYSIS ELNEDDRRKV EEIKAELFGH GRTTDLSKGL QSPRGMGCKP EAVCSHIIIE
2590 2600 2610 2620 2630 2640
SHEKGCFRTL TSEHPQLDRH PCAFRSAGPS EMTRGRQNPS SCRAKHVNLS ASLDQNNSHF
2650 2660 2670 2680 2690 2700
KVWNSLQLKS HSPFQNFIPD EFKISKGLRM PFDEKMDPWL SELVEPAFVP PKEVDFHSSS
2710 2720 2730 2740 2750 2760
QMPSPEPMKK FTTSITFSSH RHSKCISNSS VVKVGVTEGS QCTGASVGVF NSHFTEEQNP
2770 2780 2790 2800 2810 2820
PRDLKQKTSS PSSFKMHSNS QDKEVTILAE GRRQSQKLPV DFERSFQEEK PLERSDFTGS
2830 2840 2850 2860 2870 2880
HSEPSTRANC SNFKEIQISD NHTLISMGRP SSTLGVNRSS SRLGVKEKNV TITPDLPSCI
2890 2900 2910 2920 2930 2940
FLEQRELFEQ SKAPRADDHV RKHHSPSPQH QDYVAPDLPS CIFLEQRELF EQCKAPYVDH
2950 2960 2970 2980 2990 3000
QMRENHSPLP QGQDSIASDL PSPISLEQCQ SKAPGVDDQM NKHHFPLPQG QDCVVEKNNQ
3010 3020 3030 3040 3050 3060
HKPKSHISNI NVEAKFNTVV SQSAPNHCTL AASASTPPSN RKALSCVHIT LCPKTSSKLD
3070 3080 3090 3100 3110 3120
SGTLDERFHS LDAASKARMN SEFNFDLHTV SSRSLEPTSK LLTSKPVAQD QESLGFLGPK
3130 3140 3150 3160 3170 3180
SSLDFQVVQP SLPDSNTITQ DLKTIPSQNS QIVTSRQIQV NISDFEGHSN PEGTPVFADR
3190 3200 3210 3220 3230 3240
LPEKMKTPLS AFSEKLSSDA VTQITTESPE KTLFSSEIFI NAEDRGHEII EPGNQKLRKA
3250 3260 3270 3280 3290 3300
PVKFASSSSV QQVTFSRGTD GQPLLLPYKP SGSTKMYYVP QLRQIPPSPD SKSDTTVESS
3310 3320 3330 3340 3350 3360
HSGSNDAIAP DFPAQVLGTR DDDLSATVNI KHKEGIYSKR VVTKASLPVG EKPLQNENAD
3370 3380 3390 3400 3410 3420
ASVQVLITGD ENLSDKKQQE IHSTRAVTEA AQAKEKESLQ KDTADSSAAA AAEHSAQVGD
3430 3440 3450 3460 3470 3480
PEMKNLPDTK AITQKEEIHR KKTVPEEAWP NNKESLQINI EESECHSEFE NTTRSVFRSA
3490 3500 3510 3520 3530 3540
KFYIHHPVHL PSDQDICHES LGKSVFMRHS WKDFFQHHPD KHREHMCLPL PYQNMDKTKT
3550 3560 3570 3580 3590 3600
DYTRIKSLSI NVNLGNKEVM DTTKSQVRDY PKHNGQISDP QRDQKVTPEQ TTQHTVSLNE
3610 3620 3630 3640 3650 3660
LWNKYRERQR QQRQPELGDR KELSLVDRLD RLAKILQNPI THSLQVSEST HDDSRGERSV
3670 3680 3690 3700 3710 3720
KEWSGRQQQR NKLQKKKRFK SLEKSHKNTG ELKKSKVLSH HRAGRSNQIK IEQIKFDKYI
3730 3740 3750 3760 3770 3780
LSKQPGFNYI SNTSSDCRPS EESELLTDTT TNILSGTTST VESDILTQTD REVALHERSS
3790 3800 3810 3820 3830 3840
SVSTIDTARL IQAFGHERVC LSPRRIKLYS SITNQQRRYL EKRSKHSKKV LNTGHPLVTS
3850 3860 3870 3880 3890 3900
EHTRRRHIQV ANHVISSDSI SSSASSFLSS NSTFCNKQNV HMLNKGIQAG NLEIVNGAKK
3910 3920 3930 3940 3950 3960
HTRDVGITFP TPSSSEAKLE ENSDVTSWSE EKREEKMLFT GYPEDRKLKK NKKNSHEGVS
3970 3980 3990 4000 4010 4020
WFVPVENVES RSKKENVPNT CGPGISWFEP ITKTRPWREP LREQNCQGQH LDGRGYLAGP
4030 4040 4050 4060 4070 4080
GREAGRDLLR PFVRATLQES LQFHRPDFIS RSGERIKRLK LIVQERKLQS MLQTERDALF
4090 4100 4110 4120 4130 4140
NIDRERQGHQ NRMCPLPKRV FLAIQKNKPI SKKEMIQRSK RIYEQLPEVQ KKREEEKRKS
4150 4160
EYKSYRLRAQ LYKKRVTNQL LGRKVPWD
Protein Neighborhood
Domains & Features
3 N-termini - 2 C-termini - 0 Cleavages - 0 Substrates
N-termini
| Name | Sequence | Position | Modification | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMID) |
|---|---|---|---|---|---|---|---|---|---|
| Q8TCU4-1-unknown | MEPEDL... | 1 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
| Q8TCU4-1-unknown | MEPEDL... | 1 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt66762 | |||
| Q8TCU4-1-unknown | MEPEDL... | 1 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt66763 | |||
| Q8TCU4-827- | DSHLPE... | 827 | Subtiligase Based Positive Selection | Wells | apoptotic_MM1s_bort | 23264352 | |||
| Q8TCU4-827-unknown | DSHLPE... | 827 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt176413 | |||
| Q8TCU4-827-unknown | DSHLPE... | 827 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt176414 |
C-termini
| Name | Sequence | Position | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
|---|---|---|---|---|---|---|---|---|
| ...IQRSKR | 4120 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt62380 | |||
| ...RKVPWD | 4167 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot |
Cleavages
| Protease | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
|---|
Substrates
| Substrate | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
|---|