TopFIND 4.0

Q8TD08: Mitogen-activated protein kinase 15 {ECO:0000305}

General Information

Protein names
- Mitogen-activated protein kinase 15 {ECO:0000305}
- MAP kinase 15
- MAPK 15
- 2.7.11.24
- Extracellular signal-regulated kinase 7
- ERK-7
- Extracellular signal-regulated kinase 8
- ERK-8
Gene names MAPK15
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID Q8TD08

1

N-termini

2

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MCTVVDPRIV RRYLLRRQLG QGAYGIVWKA VDRRTGEVVA IKKIFDAFRD KTDAQRTFRE 
        70         80         90        100        110        120 
ITLLQEFGDH PNIISLLDVI RAENDRDIYL VFEFMDTDLN AVIRKGGLLQ DVHVRSIFYQ 
       130        140        150        160        170        180 
LLRATRFLHS GHVVHRDQKP SNVLLDANCT VKLCDFGLAR SLGDLPEGPE DQAVTEYVAT 
       190        200        210        220        230        240 
RWYRAPEVLL SSHRYTLGVD MWSLGCILGE MLRGRPLFPG TSTLHQLELI LETIPPPSEE 
       250        260        270        280        290        300 
DLLALGSGCR ASVLHQLGSR PRQTLDALLP PDTSPEALDL LRRLLVFAPD KRLSATQALQ 
       310        320        330        340        350        360 
HPYVQRFHCP SDEWAREADV RPRAHEGVQL SVPEYRSRVY QMILECGGSS GTSREKGPEG 
       370        380        390        400        410        420 
VSPSQAHLHK PRADPQLPSR TPVQGPRPRP QSSPGHDPAE HESPRAAKNV PRQNSAPLLQ 
       430        440        450        460        470        480 
TALLGNGERP PGAKEAPPLT LSLVKPSGRG AAPSLTSQAA AQVANQALIR GDWNRGGGVR 
       490        500        510        520        530        540 
VASVQQVPPR LPPEARPGRR MFSTSALQGA QGGARALLGG YSQAYGTVCH SALGHLPLLE 
   
GHHV

Isoforms

- Isoform 2 of Mitogen-activated protein kinase 15 - Isoform 3 of Mitogen-activated protein kinase 15

Sequence View

        10         20         30         40         50         60 
MCTVVDPRIV RRYLLRRQLG QGAYGIVWKA VDRRTGEVVA IKKIFDAFRD KTDAQRTFRE 
        70         80         90        100        110        120 
ITLLQEFGDH PNIISLLDVI RAENDRDIYL VFEFMDTDLN AVIRKGGLLQ DVHVRSIFYQ 
       130        140        150        160        170        180 
LLRATRFLHS GHVVHRDQKP SNVLLDANCT VKLCDFGLAR SLGDLPEGPE DQAVTEYVAT 
       190        200        210        220        230        240 
RWYRAPEVLL SSHRYTLGVD MWSLGCILGE MLRGRPLFPG TSTLHQLELI LETIPPPSEE 
       250        260        270        280        290        300 
DLLALGSGCR ASVLHQLGSR PRQTLDALLP PDTSPEALDL LRRLLVFAPD KRLSATQALQ 
       310        320        330        340        350        360 
HPYVQRFHCP SDEWAREADV RPRAHEGVQL SVPEYRSRVY QMILECGGSS GTSREKGPEG 
       370        380        390        400        410        420 
VSPSQAHLHK PRADPQLPSR TPVQGPRPRP QSSPGHDPAE HESPRAAKNV PRQNSAPLLQ 
       430        440        450        460        470        480 
TALLGNGERP PGAKEAPPLT LSLVKPSGRG AAPSLTSQAA AQVANQALIR GDWNRGGGVR 
       490        500        510        520        530        540 
VASVQQVPPR LPPEARPGRR MFSTSALQGA QGGARALLGG YSQAYGTVCH SALGHLPLLE 
   
GHHV         10         20         30         40         50         60 
MCTVVDPRIV RRYLLRRQLG QGAYGIVWKA VDRRTGEVVA IKKIFDAFRD KTDAQRTFRE 
        70         80         90        100        110        120 
ITLLQEFGDH PNIISLLDVI RAENDRDIYL VFEFMDTDLN AVIRKGGLLQ DVHVRSIFYQ 
       130        140        150        160        170        180 
LLRATRFLHS GHVVHRDQKP SNVLLDANCT VKLCDFGLAR SLGDLPEGPE DQAVTEYVAT 
       190        200        210        220        230        240 
RWYRAPEVLL SSHRYTLGVD MWSLGCILGE MLRGRPLFPG TSTLHQLELI LETIPPPSEE 
       250        260        270        280        290        300 
DLLALGSGCR ASVLHQLGSR PRQTLDALLP PDTSPEALDL LRRLLVFAPD KRLSATQALQ 
       310        320        330        340        350        360 
HPYVQRFHCP SDEWAREADV RPRAHEGVQL SVPEYRSRVY QMILECGGSS GTSREKGPEG 
       370        380        390        400        410        420 
VSPSQAHLHK PRADPQLPSR TPVQGPRPRP QSSPGHDPAE HESPRAAKNV PRQNSAPLLQ 
       430        440        450        460        470        480 
TALLGNGERP PGAKEAPPLT LSLVKPSGRG AAPSLTSQAA AQVANQALIR GDWNRGGGVR 
       490        500        510        520        530        540 
VASVQQVPPR LPPEARPGRR MFSTSALQGA QGGARALLGG YSQAYGTVCH SALGHLPLLE 
   
GHHV



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Evidence Codes:


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Biological System:


Protease Assignment Confidence:


Evidence Names:


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Lab:



Protein Neighborhood

Domains & Features

1 N-termini - 2 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    Q8TD08-1-unknown MCTVVD... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    Q8TD08-1-unknown MCTVVD... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt81221
    Q8TD08-1-unknown MCTVVD... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt81222

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...QLGSRP 260 inferred from isoform by sequence similarity unknown TopFIND inferred from TCt76840
    ...EGHHV 544 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)