TopFIND 4.0

Q8TDD5: Mucolipin-3 {ECO:0000303|PubMed:19497048}

General Information

Protein names
- Mucolipin-3 {ECO:0000303|PubMed:19497048}
- Transient receptor potential channel mucolipin 3
- TRPML3 {ECO:0000303|PubMed:18369318}
Gene names MCOLN3
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID Q8TDD5

1

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MADPEVVVSS CSSHEEENRC NFNQQTSPSE ELLLEDQMRR KLKFFFMNPC EKFWARGRKP 
        70         80         90        100        110        120 
WKLAIQILKI AMVTIQLVLF GLSNQMVVAF KEENTIAFKH LFLKGYMDRM DDTYAVYTQS 
       130        140        150        160        170        180 
DVYDQLIFAV NQYLQLYNVS VGNHAYENKG TKQSAMAICQ HFYKRGNIYP GNDTFDIDPE 
       190        200        210        220        230        240 
IETECFFVEP DEPFHIGTPA ENKLNLTLDF HRLLTVELQF KLKAINLQTV RHQELPDCYD 
       250        260        270        280        290        300 
FTLTITFDNK AHSGRIKISL DNDISIRECK DWHVSGSIQK NTHYMMIFDA FVILTCLVSL 
       310        320        330        340        350        360 
ILCIRSVIRG LQLQQEFVNF FLLHYKKEVS VSDQMEFVNG WYIMIIISDI LTIIGSILKM 
       370        380        390        400        410        420 
EIQAKSLTSY DVCSILLGTS TMLVWLGVIR YLGFFAKYNL LILTLQAALP NVIRFCCCAA 
       430        440        450        460        470        480 
MIYLGYCFCG WIVLGPYHDK FRSLNMVSEC LFSLINGDDM FATFAKMQQK SYLVWLFSRI 
       490        500        510        520        530        540 
YLYSFISLFI YMILSLFIAL ITDTYETIKQ YQQDGFPETE LRTFISECKD LPNSGKYRLE 
       550    
DDPPVSLFCC CKK

Isoforms

- Isoform 2 of Mucolipin-3

Sequence View

        10         20         30         40         50         60 
MADPEVVVSS CSSHEEENRC NFNQQTSPSE ELLLEDQMRR KLKFFFMNPC EKFWARGRKP 
        70         80         90        100        110        120 
WKLAIQILKI AMVTIQLVLF GLSNQMVVAF KEENTIAFKH LFLKGYMDRM DDTYAVYTQS 
       130        140        150        160        170        180 
DVYDQLIFAV NQYLQLYNVS VGNHAYENKG TKQSAMAICQ HFYKRGNIYP GNDTFDIDPE 
       190        200        210        220        230        240 
IETECFFVEP DEPFHIGTPA ENKLNLTLDF HRLLTVELQF KLKAINLQTV RHQELPDCYD 
       250        260        270        280        290        300 
FTLTITFDNK AHSGRIKISL DNDISIRECK DWHVSGSIQK NTHYMMIFDA FVILTCLVSL 
       310        320        330        340        350        360 
ILCIRSVIRG LQLQQEFVNF FLLHYKKEVS VSDQMEFVNG WYIMIIISDI LTIIGSILKM 
       370        380        390        400        410        420 
EIQAKSLTSY DVCSILLGTS TMLVWLGVIR YLGFFAKYNL LILTLQAALP NVIRFCCCAA 
       430        440        450        460        470        480 
MIYLGYCFCG WIVLGPYHDK FRSLNMVSEC LFSLINGDDM FATFAKMQQK SYLVWLFSRI 
       490        500        510        520        530        540 
YLYSFISLFI YMILSLFIAL ITDTYETIKQ YQQDGFPETE LRTFISECKD LPNSGKYRLE 
       550    
DDPPVSLFCC CKK



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Directness:


Physiological Relevance:


Evidence Codes:


Methodology:


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Biological System:


Protease Assignment Confidence:


Evidence Names:


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Protein Neighborhood

Domains & Features

1 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    Q8TDD5-1-unknown MADPEV... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    Q8TDD5-1-unknown MADPEV... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt80626

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...CCCKK 553 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    ...CCCKK 553 inferred from isoform by sequence similarity unknown TopFIND inferred from TCt76244

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)