TopFIND 4.0

Q8TDF5: Neuropilin and tolloid-like protein 1

General Information

Protein names
- Neuropilin and tolloid-like protein 1
- Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 1
Gene names NETO1
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID Q8TDF5

1

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MIHGRSVLHI VASLIILHLS GATKKGTEKQ TTSETQKSVQ CGTWTKHAEG GIFTSPNYPS 
        70         80         90        100        110        120 
KYPPDRECIY IIEAAPRQCI ELYFDEKYSI EPSWECKFDH IEVRDGPFGF SPIIGRFCGQ 
       130        140        150        160        170        180 
QNPPVIKSSG RFLWIKFFAD GELESMGFSA RYNFTPDPDF KDLGALKPLP ACEFEMGGSE 
       190        200        210        220        230        240 
GIVESIQIMK EGKATASEAV DCKWYIRAPP RSKIYLRFLD YEMQNSNECK RNFVAVYDGS 
       250        260        270        280        290        300 
SSVEDLKAKF CSTVANDVML RTGLGVIRMW ADEGSRNSRF QMLFTSFQEP PCEGNTFFCH 
       310        320        330        340        350        360 
SNMCINNTLV CNGLQNCVYP WDENHCKEKR KTSLLDQLTN TSGTVIGVTS CIVIILIIIS 
       370        380        390        400        410        420 
VIVQIKQPRK KYVQRKSDFD QTVFQEVFEP PHYELCTLRG TGATADFADV ADDFENYHKL 
       430        440        450        460        470        480 
RRSSSKCIHD HHCGSQLSST KGSRSNLSTR DASILTEMPT QPGKPLIPPM NRRNILVMKH 
       490        500        510        520        530    
SYSQDAADAC DIDEIEEVPT TSHRLSRHDK AVQRFCLIGS LSKHESEYNT TRV

Isoforms

- Isoform 1 of Neuropilin and tolloid-like protein 1 - Isoform 2 of Neuropilin and tolloid-like protein 1

Sequence View

        10         20         30         40         50         60 
MIHGRSVLHI VASLIILHLS GATKKGTEKQ TTSETQKSVQ CGTWTKHAEG GIFTSPNYPS 
        70         80         90        100        110        120 
KYPPDRECIY IIEAAPRQCI ELYFDEKYSI EPSWECKFDH IEVRDGPFGF SPIIGRFCGQ 
       130        140        150        160        170        180 
QNPPVIKSSG RFLWIKFFAD GELESMGFSA RYNFTPDPDF KDLGALKPLP ACEFEMGGSE 
       190        200        210        220        230        240 
GIVESIQIMK EGKATASEAV DCKWYIRAPP RSKIYLRFLD YEMQNSNECK RNFVAVYDGS 
       250        260        270        280        290        300 
SSVEDLKAKF CSTVANDVML RTGLGVIRMW ADEGSRNSRF QMLFTSFQEP PCEGNTFFCH 
       310        320        330        340        350        360 
SNMCINNTLV CNGLQNCVYP WDENHCKEKR KTSLLDQLTN TSGTVIGVTS CIVIILIIIS 
       370        380        390        400        410        420 
VIVQIKQPRK KYVQRKSDFD QTVFQEVFEP PHYELCTLRG TGATADFADV ADDFENYHKL 
       430        440        450        460        470        480 
RRSSSKCIHD HHCGSQLSST KGSRSNLSTR DASILTEMPT QPGKPLIPPM NRRNILVMKH 
       490        500        510        520        530    
SYSQDAADAC DIDEIEEVPT TSHRLSRHDK AVQRFCLIGS LSKHESEYNT TRV         10         20         30         40         50         60 
MIHGRSVLHI VASLIILHLS GATKKGTEKQ TTSETQKSVQ CGTWTKHAEG GIFTSPNYPS 
        70         80         90        100        110        120 
KYPPDRECIY IIEAAPRQCI ELYFDEKYSI EPSWECKFDH IEVRDGPFGF SPIIGRFCGQ 
       130        140        150        160        170        180 
QNPPVIKSSG RFLWIKFFAD GELESMGFSA RYNFTPDPDF KDLGALKPLP ACEFEMGGSE 
       190        200        210        220        230        240 
GIVESIQIMK EGKATASEAV DCKWYIRAPP RSKIYLRFLD YEMQNSNECK RNFVAVYDGS 
       250        260        270        280        290        300 
SSVEDLKAKF CSTVANDVML RTGLGVIRMW ADEGSRNSRF QMLFTSFQEP PCEGNTFFCH 
       310        320        330        340        350        360 
SNMCINNTLV CNGLQNCVYP WDENHCKEKR KTSLLDQLTN TSGTVIGVTS CIVIILIIIS 
       370        380        390        400        410        420 
VIVQIKQPRK KYVQRKSDFD QTVFQEVFEP PHYELCTLRG TGATADFADV ADDFENYHKL 
       430        440        450        460        470        480 
RRSSSKCIHD HHCGSQLSST KGSRSNLSTR DASILTEMPT QPGKPLIPPM NRRNILVMKH 
       490        500        510        520        530    
SYSQDAADAC DIDEIEEVPT TSHRLSRHDK AVQRFCLIGS LSKHESEYNT TRV



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Protease Assignment Confidence:


Evidence Names:


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Protein Neighborhood

Domains & Features

1 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    Q8TDF5-23-unknown TKKGTE... 23 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    Q8TDF5-23-unknown TKKGTE... 23 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt113346

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...NTTRV 533 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    ...NTTRV 533 inferred from isoform by sequence similarity unknown TopFIND inferred from TCt78251

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)