TopFIND 4.0

Q8TE67: Epidermal growth factor receptor kinase substrate 8-like protein 3

General Information

Protein names
- Epidermal growth factor receptor kinase substrate 8-like protein 3
- EPS8-like protein 3
- Epidermal growth factor receptor pathway substrate 8-related protein 3
- EPS8-related protein 3
Gene names EPS8L3
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID Q8TE67

1

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MSRPSSRAIY LHRKEYSQNL TSEPTLLQHR VEHLMTCKQG SQRVQGPEDA LQKLFEMDAQ 
        70         80         90        100        110        120 
GRVWSQDLIL QVRDGWLQLL DIETKEELDS YRLDSIQAMN VALNTCSYNS ILSITVQEPG 
       130        140        150        160        170        180 
LPGTSTLLFQ CQEVGAERLK TSLQKALEEE LEQRPRLGGL QPGQDRWRGP AMERPLPMEQ 
       190        200        210        220        230        240 
ARYLEPGIPP EQPHQRTLEH SLPPSPRPLP RHTSAREPSA FTLPPPRRSS SPEDPERDEE 
       250        260        270        280        290        300 
VLNHVLRDIE LFMGKLEKAQ AKTSRKKKFG KKNKDQGGLT QAQYIDCFQK IKHSFNLLGR 
       310        320        330        340        350        360 
LATWLKETSA PELVHILFKS LNFILARCPE AGLAAQVISP LLTPKAINLL QSCLSPPESN 
       370        380        390        400        410        420 
LWMGLGPAWT TSRADWTGDE PLPYQPTFSD DWQLPEPSSQ APLGYQDPVS LRRGSHRLGS 
       430        440        450        460        470        480 
TSHFPQEKTH NHDPQPGDPN SRPSSPKPAQ PALKMQVLYE FEARNPRELT VVQGEKLEVL 
       490        500        510        520        530        540 
DHSKRWWLVK NEAGRSGYIP SNILEPLQPG TPGTQGQSPS RVPMLRLSSR PEEVTDWLQA 
       550        560        570        580        590    
ENFSTATVRT LGSLTGSQLL RIRPGELQML CPQEAPRILS RLEAVRRMLG ISP

Isoforms

- Isoform 2 of Epidermal growth factor receptor kinase substrate 8-like protein 3 - Isoform 3 of Epidermal growth factor receptor kinase substrate 8-like protein 3

Sequence View

        10         20         30         40         50         60 
MSRPSSRAIY LHRKEYSQNL TSEPTLLQHR VEHLMTCKQG SQRVQGPEDA LQKLFEMDAQ 
        70         80         90        100        110        120 
GRVWSQDLIL QVRDGWLQLL DIETKEELDS YRLDSIQAMN VALNTCSYNS ILSITVQEPG 
       130        140        150        160        170        180 
LPGTSTLLFQ CQEVGAERLK TSLQKALEEE LEQRPRLGGL QPGQDRWRGP AMERPLPMEQ 
       190        200        210        220        230        240 
ARYLEPGIPP EQPHQRTLEH SLPPSPRPLP RHTSAREPSA FTLPPPRRSS SPEDPERDEE 
       250        260        270        280        290        300 
VLNHVLRDIE LFMGKLEKAQ AKTSRKKKFG KKNKDQGGLT QAQYIDCFQK IKHSFNLLGR 
       310        320        330        340        350        360 
LATWLKETSA PELVHILFKS LNFILARCPE AGLAAQVISP LLTPKAINLL QSCLSPPESN 
       370        380        390        400        410        420 
LWMGLGPAWT TSRADWTGDE PLPYQPTFSD DWQLPEPSSQ APLGYQDPVS LRRGSHRLGS 
       430        440        450        460        470        480 
TSHFPQEKTH NHDPQPGDPN SRPSSPKPAQ PALKMQVLYE FEARNPRELT VVQGEKLEVL 
       490        500        510        520        530        540 
DHSKRWWLVK NEAGRSGYIP SNILEPLQPG TPGTQGQSPS RVPMLRLSSR PEEVTDWLQA 
       550        560        570        580        590    
ENFSTATVRT LGSLTGSQLL RIRPGELQML CPQEAPRILS RLEAVRRMLG ISP         10         20         30         40         50         60 
MSRPSSRAIY LHRKEYSQNL TSEPTLLQHR VEHLMTCKQG SQRVQGPEDA LQKLFEMDAQ 
        70         80         90        100        110        120 
GRVWSQDLIL QVRDGWLQLL DIETKEELDS YRLDSIQAMN VALNTCSYNS ILSITVQEPG 
       130        140        150        160        170        180 
LPGTSTLLFQ CQEVGAERLK TSLQKALEEE LEQRPRLGGL QPGQDRWRGP AMERPLPMEQ 
       190        200        210        220        230        240 
ARYLEPGIPP EQPHQRTLEH SLPPSPRPLP RHTSAREPSA FTLPPPRRSS SPEDPERDEE 
       250        260        270        280        290        300 
VLNHVLRDIE LFMGKLEKAQ AKTSRKKKFG KKNKDQGGLT QAQYIDCFQK IKHSFNLLGR 
       310        320        330        340        350        360 
LATWLKETSA PELVHILFKS LNFILARCPE AGLAAQVISP LLTPKAINLL QSCLSPPESN 
       370        380        390        400        410        420 
LWMGLGPAWT TSRADWTGDE PLPYQPTFSD DWQLPEPSSQ APLGYQDPVS LRRGSHRLGS 
       430        440        450        460        470        480 
TSHFPQEKTH NHDPQPGDPN SRPSSPKPAQ PALKMQVLYE FEARNPRELT VVQGEKLEVL 
       490        500        510        520        530        540 
DHSKRWWLVK NEAGRSGYIP SNILEPLQPG TPGTQGQSPS RVPMLRLSSR PEEVTDWLQA 
       550        560        570        580        590    
ENFSTATVRT LGSLTGSQLL RIRPGELQML CPQEAPRILS RLEAVRRMLG ISP



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Protease Assignment Confidence:


Evidence Names:


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Protein Neighborhood

Domains & Features

1 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    Q8TE67-1-unknown MSRPSS... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    Q8TE67-1-unknown MSRPSS... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt74181
    Q8TE67-1-unknown MSRPSS... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt74182

C-termini

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)