Q8TEL6: Short transient receptor potential channel 4-associated protein

General Information

Protein names	- Short transient receptor potential channel 4-associated protein - Trp4-associated protein - Trpc4-associated protein - Protein TAP1 - TNF-receptor ubiquitous scaffolding/signaling protein - Protein TRUSS
Gene names	TRPC4AP
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q8TEL6

3 N-termini

2 C-termini

0 Cleavages

0 Substrates

Sequence

Isoforms

- Isoform 2 of Short transient receptor potential channel 4-associated protein - Isoform 3 of Short transient receptor potential channel 4-associated protein

Sequence View

        10         20         30         40         50         60
MAAAPVAAGS GAGRGRRSAA TVAAWGGWGG RPRPGNILLQ LRQGQLTGRG LVRAVQFTET
        70         80         90        100        110        120
FLTERDKQSK WSGIPQLLLK LHTTSHLHSD FVECQNILKE ISPLLSMEAM AFVTEERKLT
       130        140        150        160        170        180
QETTYPNTYI FDLFGGVDLL VEILMRPTIS IRGQKLKISD EMSKDCLSIL YNTCVCTEGV
       190        200        210        220        230        240
TKRLAEKNDF VIFLFTLMTS KKTFLQTATL IEDILGVKKE MIRLDEVPNL SSLVSNFDQQ
       250        260        270        280        290        300
QLANFCRILA VTISEMDTGN DDKHTLLAKN AQQKKSLSLG PSAAEINQAA LLSIPGFVER
       310        320        330        340        350        360
LCKLATRKVS ESTGTASFLQ ELEEWYTWLD NALVLDALMR VANEESEHNQ ASIVFPPPGA
       370        380        390        400        410        420
SEENGLPHTS ARTQLPQSMK IMHEIMYKLE VLYVLCVLLM GRQRNQVHRM IAEFKLIPGL
       430        440        450        460        470        480
NNLFDKLIWR KHSASALVLH GHNQNCDCSP DITLKIQFLR LLQSFSDHHE NKYLLLNNQE
       490        500        510        520        530        540
LNELSAISLK ANIPEVEAVL NTDRSLVCDG KRGLLTRLLQ VMKKEPAESS FRFWQARAVE
       550        560        570        580        590        600
SFLRGTTSYA DQMFLLKRGL LEHILYCIVD SECKSRDVLQ SYFDLLGELM KFNVDAFKRF
       610        620        630        640        650        660
NKYINTDAKF QVFLKQINSS LVDSNMLVRC VTLSLDRFEN QVDMKVAEVL SECRLLAYIS
       670        680        690        700        710        720
QVPTQMSFLF RLINIIHVQT LTQENVSCLN TSLVILMLAR RKERLPLYLR LLQRMEHSKK
       730        740        750        760        770        780
YPGFLLNNFH NLLRFWQQHY LHKDKDSTCL ENSSCISFSY WKETVSILLN PDRQSPSALV
       790
SYIEEPYMDI DRDFTEE         10         20         30         40         50         60
MAAAPVAAGS GAGRGRRSAA TVAAWGGWGG RPRPGNILLQ LRQGQLTGRG LVRAVQFTET
        70         80         90        100        110        120
FLTERDKQSK WSGIPQLLLK LHTTSHLHSD FVECQNILKE ISPLLSMEAM AFVTEERKLT
       130        140        150        160        170        180
QETTYPNTYI FDLFGGVDLL VEILMRPTIS IRGQKLKISD EMSKDCLSIL YNTCVCTEGV
       190        200        210        220        230        240
TKRLAEKNDF VIFLFTLMTS KKTFLQTATL IEDILGVKKE MIRLDEVPNL SSLVSNFDQQ
       250        260        270        280        290        300
QLANFCRILA VTISEMDTGN DDKHTLLAKN AQQKKSLSLG PSAAEINQAA LLSIPGFVER
       310        320        330        340        350        360
LCKLATRKVS ESTGTASFLQ ELEEWYTWLD NALVLDALMR VANEESEHNQ ASIVFPPPGA
       370        380        390        400        410        420
SEENGLPHTS ARTQLPQSMK IMHEIMYKLE VLYVLCVLLM GRQRNQVHRM IAEFKLIPGL
       430        440        450        460        470        480
NNLFDKLIWR KHSASALVLH GHNQNCDCSP DITLKIQFLR LLQSFSDHHE NKYLLLNNQE
       490        500        510        520        530        540
LNELSAISLK ANIPEVEAVL NTDRSLVCDG KRGLLTRLLQ VMKKEPAESS FRFWQARAVE
       550        560        570        580        590        600
SFLRGTTSYA DQMFLLKRGL LEHILYCIVD SECKSRDVLQ SYFDLLGELM KFNVDAFKRF
       610        620        630        640        650        660
NKYINTDAKF QVFLKQINSS LVDSNMLVRC VTLSLDRFEN QVDMKVAEVL SECRLLAYIS
       670        680        690        700        710        720
QVPTQMSFLF RLINIIHVQT LTQENVSCLN TSLVILMLAR RKERLPLYLR LLQRMEHSKK
       730        740        750        760        770        780
YPGFLLNNFH NLLRFWQQHY LHKDKDSTCL ENSSCISFSY WKETVSILLN PDRQSPSALV
       790
SYIEEPYMDI DRDFTEE

Filter Information:

(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

3 N-termini - 2 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
Q8TEL6-1-unknown	MAAAPV...	1		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt92786
Q8TEL6-1-unknown	MAAAPV...	1		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt92787
Q8TEL6-2-unknown	MAAAPV...	1		inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q8TEL6-2-Acetylation	AAAPVA...	2	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q8TEL6-2-Acetylation	AAAPVA...	2	acetylation-		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345
Q8TEL6-2-Acetylation	AAAPVA...	2	acetylation-		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345
Q8TEL6-2-Acetylation	AAAPVA...	2	acetylation-	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt111637
Q8TEL6-2-Acetylation	AAAPVA...	2	acetylation-	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt111638

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...ESSFRF	532	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt88404
...ESSFRF	532	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt93019
...DFTEE	797	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...DFTEE	797	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt88405

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)