TopFIND 4.0

Q8VBW1: Sodium- and chloride-dependent creatine transporter 1

General Information

Protein names
- Sodium- and chloride-dependent creatine transporter 1
- CT1
- Creatine transporter 1
- Solute carrier family 6 member 8
Gene names Slc6a8
Organism Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID Q8VBW1

1

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MAKKSAENGI YSVSGDEKKG PLIVSGPDGA PAKGDGPAGL GAPGGRLAVP PRETWTRQMD 
        70         80         90        100        110        120 
FIMSCVGFAV GLGNVWRFPY LCYKNGGGVF LIPYVLIALV GGIPIFFLEI SLGQFMKAGS 
       130        140        150        160        170        180 
INVWNICPLF KGLGYASMVI VFYCNTYYIM VLAWGFYYLV KSFTTTLPWA TCGHTWNTPD 
       190        200        210        220        230        240 
CVEIFRHEDC ANASLANLTC DQLADRRSPV IEFWENKVLR LSTGLEVPGA LNWEVTLCLL 
       250        260        270        280        290        300 
ACWVLVYFCV WKGVKSTGKI VYFTATFPYV VLVVLLVRGV LLPGALDGII YYLKPDWSKL 
       310        320        330        340        350        360 
GSPQVWIDAG TQIFFSYAIG LGALTALGSY NRFNNNCYKD AIILALINSG TSFFAGFVVF 
       370        380        390        400        410        420 
SILGFMATEQ GVHISKVAES GPGLAFIAYP RAVTLMPVAP LWAALFFFML LLLGLDSQFV 
       430        440        450        460        470        480 
GVEGFITGLL DLLPASYYFR FQREISVALC CALCFVIDLS MVTDVSGGKG GMYVFQLFDY 
       490        500        510        520        530        540 
YSASGTTLLW QAFWECVVVA WVYGADRFMD DIACMIGYRP CPWMKWCWSF FTPLVCMGIF 
       550        560        570        580        590        600 
IFNIVYYEPL VYNNTYVYPW WGEAMGWAFA LSSMLCVPLH LLGCLLRAKG TMAERWQHLT 
       610        620        630        640    
QPIWGLHHLE YRAQDADVRG LTTLTPVSES SKVVVVESVM 

Isoforms

- Isoform 2 of Sodium- and chloride-dependent creatine transporter 1 - Isoform 3 of Sodium- and chloride-dependent creatine transporter 1

Sequence View

        10         20         30         40         50         60 
MAKKSAENGI YSVSGDEKKG PLIVSGPDGA PAKGDGPAGL GAPGGRLAVP PRETWTRQMD 
        70         80         90        100        110        120 
FIMSCVGFAV GLGNVWRFPY LCYKNGGGVF LIPYVLIALV GGIPIFFLEI SLGQFMKAGS 
       130        140        150        160        170        180 
INVWNICPLF KGLGYASMVI VFYCNTYYIM VLAWGFYYLV KSFTTTLPWA TCGHTWNTPD 
       190        200        210        220        230        240 
CVEIFRHEDC ANASLANLTC DQLADRRSPV IEFWENKVLR LSTGLEVPGA LNWEVTLCLL 
       250        260        270        280        290        300 
ACWVLVYFCV WKGVKSTGKI VYFTATFPYV VLVVLLVRGV LLPGALDGII YYLKPDWSKL 
       310        320        330        340        350        360 
GSPQVWIDAG TQIFFSYAIG LGALTALGSY NRFNNNCYKD AIILALINSG TSFFAGFVVF 
       370        380        390        400        410        420 
SILGFMATEQ GVHISKVAES GPGLAFIAYP RAVTLMPVAP LWAALFFFML LLLGLDSQFV 
       430        440        450        460        470        480 
GVEGFITGLL DLLPASYYFR FQREISVALC CALCFVIDLS MVTDVSGGKG GMYVFQLFDY 
       490        500        510        520        530        540 
YSASGTTLLW QAFWECVVVA WVYGADRFMD DIACMIGYRP CPWMKWCWSF FTPLVCMGIF 
       550        560        570        580        590        600 
IFNIVYYEPL VYNNTYVYPW WGEAMGWAFA LSSMLCVPLH LLGCLLRAKG TMAERWQHLT 
       610        620        630        640    
QPIWGLHHLE YRAQDADVRG LTTLTPVSES SKVVVVESVM          10         20         30         40         50         60 
MAKKSAENGI YSVSGDEKKG PLIVSGPDGA PAKGDGPAGL GAPGGRLAVP PRETWTRQMD 
        70         80         90        100        110        120 
FIMSCVGFAV GLGNVWRFPY LCYKNGGGVF LIPYVLIALV GGIPIFFLEI SLGQFMKAGS 
       130        140        150        160        170        180 
INVWNICPLF KGLGYASMVI VFYCNTYYIM VLAWGFYYLV KSFTTTLPWA TCGHTWNTPD 
       190        200        210        220        230        240 
CVEIFRHEDC ANASLANLTC DQLADRRSPV IEFWENKVLR LSTGLEVPGA LNWEVTLCLL 
       250        260        270        280        290        300 
ACWVLVYFCV WKGVKSTGKI VYFTATFPYV VLVVLLVRGV LLPGALDGII YYLKPDWSKL 
       310        320        330        340        350        360 
GSPQVWIDAG TQIFFSYAIG LGALTALGSY NRFNNNCYKD AIILALINSG TSFFAGFVVF 
       370        380        390        400        410        420 
SILGFMATEQ GVHISKVAES GPGLAFIAYP RAVTLMPVAP LWAALFFFML LLLGLDSQFV 
       430        440        450        460        470        480 
GVEGFITGLL DLLPASYYFR FQREISVALC CALCFVIDLS MVTDVSGGKG GMYVFQLFDY 
       490        500        510        520        530        540 
YSASGTTLLW QAFWECVVVA WVYGADRFMD DIACMIGYRP CPWMKWCWSF FTPLVCMGIF 
       550        560        570        580        590        600 
IFNIVYYEPL VYNNTYVYPW WGEAMGWAFA LSSMLCVPLH LLGCLLRAKG TMAERWQHLT 
       610        620        630        640    
QPIWGLHHLE YRAQDADVRG LTTLTPVSES SKVVVVESVM 



Filter Information:


(REFRESH)

Directness:


Physiological Relevance:


Evidence Codes:


Methodology:


Perturbation of System:


Biological System:


Protease Assignment Confidence:


Evidence Names:


Database:


Lab:



Protein Neighborhood

Domains & Features

1 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    Q8VBW1-1-unknown MAKKSA... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    Q8VBW1-1-unknown MAKKSA... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt88963
    Q8VBW1-1-unknown MAKKSA... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt88964

C-termini

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)