Q8VC34: Putative RNA polymerase II subunit B1 CTD phosphatase Rpap2

General Information

Protein names	- Putative RNA polymerase II subunit B1 CTD phosphatase Rpap2 - 3.1.3.16 - RNA polymerase II-associated protein 2
Gene names	Rpap2
Organism	Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID	Q8VC34

4 N-termini

3 C-termini

0 Cleavages

0 Substrates

Sequence

Isoforms

- Isoform 2 of Putative RNA polymerase II subunit B1 CTD phosphatase Rpap2 - Isoform 3 of Putative RNA polymerase II subunit B1 CTD phosphatase Rpap2 - Isoform 4 of Putative RNA polymerase II subunit B1 CTD phosphatase Rpap2 - Isoform 5 of Putative RNA polymerase II subunit B1 CTD phosphatase Rpap2 - Isoform 4 of Putative RNA polymerase II subunit B1 CTD phosphatase Rpap2 - Isoform 5 of Putative RNA polymerase II subunit B1 CTD phosphatase Rpap2

Sequence View

        10         20         30         40         50         60
MADSAVPCSL GPSTRASSTH RDATGTKQTR ALKRGDASKR QAELEAAIQR KVEFERKAVR
        70         80         90        100        110        120
IVEQLLEENI TEEFLKECGM FITPAHYSDV VDERSIIKLC GYPLCQKKLG VIPKQKYRIS
       130        140        150        160        170        180
TKTNKVYDIT ERKSFCSNFC YRASKFFETQ IPKTPVWVRE EERPPDFQLL KKGQSGSSGE
       190        200        210        220        230        240
VVQFFRDAVT AADVDGSGAL EAQCDPASSS SWSERASDEE EQGFVSSLLP GNRPKAVDTR
       250        260        270        280        290        300
PQPHTKSSIM RKKAAQNVDS KEGEQTVSEV TEQLDNCRLD SQEKVATCKR PLKKESTQIS
       310        320        330        340        350        360
SPGPLCDRFN TSAISEHKHG VSQVTLVGIS KKSAEHFRSK FAKSNPGSGS ASGLVHVRPE
       370        380        390        400        410        420
VAKANLLRVL SDTLTEWKTE ETLKFLYGQN HDSVCLKPSS ASEPDEELDE DDISCDPGSC
       430        440        450        460        470        480
GPALSQAQNT LDATLPFRGS DTAIKPLPSY ESLKKETEML NLRVREFYRG RCVLNEDTTK
       490        500        510        520        530        540
SQDSKESVLQ RDPSFPLIDS SSQNQIRRRI VLEKLSKVLP GLLGPLQITM GDIYTELKNL
       550        560        570        580        590        600
IQTFRLSNRN IIHKPVEWTL IAVVLLLLLT PILGIQKHSP KNVVFTQFIA TLLTELHLKF
       610
EDLEKLTMIF RTSC         10         20         30         40         50         60
MADSAVPCSL GPSTRASSTH RDATGTKQTR ALKRGDASKR QAELEAAIQR KVEFERKAVR
        70         80         90        100        110        120
IVEQLLEENI TEEFLKECGM FITPAHYSDV VDERSIIKLC GYPLCQKKLG VIPKQKYRIS
       130        140        150        160        170        180
TKTNKVYDIT ERKSFCSNFC YRASKFFETQ IPKTPVWVRE EERPPDFQLL KKGQSGSSGE
       190        200        210        220        230        240
VVQFFRDAVT AADVDGSGAL EAQCDPASSS SWSERASDEE EQGFVSSLLP GNRPKAVDTR
       250        260        270        280        290        300
PQPHTKSSIM RKKAAQNVDS KEGEQTVSEV TEQLDNCRLD SQEKVATCKR PLKKESTQIS
       310        320        330        340        350        360
SPGPLCDRFN TSAISEHKHG VSQVTLVGIS KKSAEHFRSK FAKSNPGSGS ASGLVHVRPE
       370        380        390        400        410        420
VAKANLLRVL SDTLTEWKTE ETLKFLYGQN HDSVCLKPSS ASEPDEELDE DDISCDPGSC
       430        440        450        460        470        480
GPALSQAQNT LDATLPFRGS DTAIKPLPSY ESLKKETEML NLRVREFYRG RCVLNEDTTK
       490        500        510        520        530        540
SQDSKESVLQ RDPSFPLIDS SSQNQIRRRI VLEKLSKVLP GLLGPLQITM GDIYTELKNL
       550        560        570        580        590        600
IQTFRLSNRN IIHKPVEWTL IAVVLLLLLT PILGIQKHSP KNVVFTQFIA TLLTELHLKF
       610
EDLEKLTMIF RTSC         10         20         30         40         50         60
MADSAVPCSL GPSTRASSTH RDATGTKQTR ALKRGDASKR QAELEAAIQR KVEFERKAVR
        70         80         90        100        110        120
IVEQLLEENI TEEFLKECGM FITPAHYSDV VDERSIIKLC GYPLCQKKLG VIPKQKYRIS
       130        140        150        160        170        180
TKTNKVYDIT ERKSFCSNFC YRASKFFETQ IPKTPVWVRE EERPPDFQLL KKGQSGSSGE
       190        200        210        220        230        240
VVQFFRDAVT AADVDGSGAL EAQCDPASSS SWSERASDEE EQGFVSSLLP GNRPKAVDTR
       250        260        270        280        290        300
PQPHTKSSIM RKKAAQNVDS KEGEQTVSEV TEQLDNCRLD SQEKVATCKR PLKKESTQIS
       310        320        330        340        350        360
SPGPLCDRFN TSAISEHKHG VSQVTLVGIS KKSAEHFRSK FAKSNPGSGS ASGLVHVRPE
       370        380        390        400        410        420
VAKANLLRVL SDTLTEWKTE ETLKFLYGQN HDSVCLKPSS ASEPDEELDE DDISCDPGSC
       430        440        450        460        470        480
GPALSQAQNT LDATLPFRGS DTAIKPLPSY ESLKKETEML NLRVREFYRG RCVLNEDTTK
       490        500        510        520        530        540
SQDSKESVLQ RDPSFPLIDS SSQNQIRRRI VLEKLSKVLP GLLGPLQITM GDIYTELKNL
       550        560        570        580        590        600
IQTFRLSNRN IIHKPVEWTL IAVVLLLLLT PILGIQKHSP KNVVFTQFIA TLLTELHLKF
       610
EDLEKLTMIF RTSC         10         20         30         40         50         60
MADSAVPCSL GPSTRASSTH RDATGTKQTR ALKRGDASKR QAELEAAIQR KVEFERKAVR
        70         80         90        100        110        120
IVEQLLEENI TEEFLKECGM FITPAHYSDV VDERSIIKLC GYPLCQKKLG VIPKQKYRIS
       130        140        150        160        170        180
TKTNKVYDIT ERKSFCSNFC YRASKFFETQ IPKTPVWVRE EERPPDFQLL KKGQSGSSGE
       190        200        210        220        230        240
VVQFFRDAVT AADVDGSGAL EAQCDPASSS SWSERASDEE EQGFVSSLLP GNRPKAVDTR
       250        260        270        280        290        300
PQPHTKSSIM RKKAAQNVDS KEGEQTVSEV TEQLDNCRLD SQEKVATCKR PLKKESTQIS
       310        320        330        340        350        360
SPGPLCDRFN TSAISEHKHG VSQVTLVGIS KKSAEHFRSK FAKSNPGSGS ASGLVHVRPE
       370        380        390        400        410        420
VAKANLLRVL SDTLTEWKTE ETLKFLYGQN HDSVCLKPSS ASEPDEELDE DDISCDPGSC
       430        440        450        460        470        480
GPALSQAQNT LDATLPFRGS DTAIKPLPSY ESLKKETEML NLRVREFYRG RCVLNEDTTK
       490        500        510        520        530        540
SQDSKESVLQ RDPSFPLIDS SSQNQIRRRI VLEKLSKVLP GLLGPLQITM GDIYTELKNL
       550        560        570        580        590        600
IQTFRLSNRN IIHKPVEWTL IAVVLLLLLT PILGIQKHSP KNVVFTQFIA TLLTELHLKF
       610
EDLEKLTMIF RTSC         10         20         30         40         50         60
MADSAVPCSL GPSTRASSTH RDATGTKQTR ALKRGDASKR QAELEAAIQR KVEFERKAVR
        70         80         90        100        110        120
IVEQLLEENI TEEFLKECGM FITPAHYSDV VDERSIIKLC GYPLCQKKLG VIPKQKYRIS
       130        140        150        160        170        180
TKTNKVYDIT ERKSFCSNFC YRASKFFETQ IPKTPVWVRE EERPPDFQLL KKGQSGSSGE
       190        200        210        220        230        240
VVQFFRDAVT AADVDGSGAL EAQCDPASSS SWSERASDEE EQGFVSSLLP GNRPKAVDTR
       250        260        270        280        290        300
PQPHTKSSIM RKKAAQNVDS KEGEQTVSEV TEQLDNCRLD SQEKVATCKR PLKKESTQIS
       310        320        330        340        350        360
SPGPLCDRFN TSAISEHKHG VSQVTLVGIS KKSAEHFRSK FAKSNPGSGS ASGLVHVRPE
       370        380        390        400        410        420
VAKANLLRVL SDTLTEWKTE ETLKFLYGQN HDSVCLKPSS ASEPDEELDE DDISCDPGSC
       430        440        450        460        470        480
GPALSQAQNT LDATLPFRGS DTAIKPLPSY ESLKKETEML NLRVREFYRG RCVLNEDTTK
       490        500        510        520        530        540
SQDSKESVLQ RDPSFPLIDS SSQNQIRRRI VLEKLSKVLP GLLGPLQITM GDIYTELKNL
       550        560        570        580        590        600
IQTFRLSNRN IIHKPVEWTL IAVVLLLLLT PILGIQKHSP KNVVFTQFIA TLLTELHLKF
       610
EDLEKLTMIF RTSC         10         20         30         40         50         60
MADSAVPCSL GPSTRASSTH RDATGTKQTR ALKRGDASKR QAELEAAIQR KVEFERKAVR
        70         80         90        100        110        120
IVEQLLEENI TEEFLKECGM FITPAHYSDV VDERSIIKLC GYPLCQKKLG VIPKQKYRIS
       130        140        150        160        170        180
TKTNKVYDIT ERKSFCSNFC YRASKFFETQ IPKTPVWVRE EERPPDFQLL KKGQSGSSGE
       190        200        210        220        230        240
VVQFFRDAVT AADVDGSGAL EAQCDPASSS SWSERASDEE EQGFVSSLLP GNRPKAVDTR
       250        260        270        280        290        300
PQPHTKSSIM RKKAAQNVDS KEGEQTVSEV TEQLDNCRLD SQEKVATCKR PLKKESTQIS
       310        320        330        340        350        360
SPGPLCDRFN TSAISEHKHG VSQVTLVGIS KKSAEHFRSK FAKSNPGSGS ASGLVHVRPE
       370        380        390        400        410        420
VAKANLLRVL SDTLTEWKTE ETLKFLYGQN HDSVCLKPSS ASEPDEELDE DDISCDPGSC
       430        440        450        460        470        480
GPALSQAQNT LDATLPFRGS DTAIKPLPSY ESLKKETEML NLRVREFYRG RCVLNEDTTK
       490        500        510        520        530        540
SQDSKESVLQ RDPSFPLIDS SSQNQIRRRI VLEKLSKVLP GLLGPLQITM GDIYTELKNL
       550        560        570        580        590        600
IQTFRLSNRN IIHKPVEWTL IAVVLLLLLT PILGIQKHSP KNVVFTQFIA TLLTELHLKF
       610
EDLEKLTMIF RTSC

Filter Information:

(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

4 N-termini - 3 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Evidence name
Q8VC34-1-unknown	MADSAV...	1		inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt88113
Q8VC34-1-unknown	MADSAV...	1		inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt88114
Q8VC34-2-unknown	MADSAV...	1		inferred from similarity	unknown	UniProtKB	inferred from uniprot (by similarity)
Q8VC34-2-unknown	MADSAV...	1		inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
Q8VC34-2-Acetylation	ADSAVP...	2	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
Q8VC34-2-Acetylation	ADSAVP...	2	acetylation-	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt110452
Q8VC34-2-Acetylation	ADSAVP...	2	acetylation-	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt110453
Q8VC34-2-Acetylation	ADSAVP...	2	acetylation-	inferred from similarity	unknown	UniProtKB	inferred from uniprot (by similarity)
Q8VC34-80-unknown	MFITPA...	80		inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSMUSP00000108269
Q8VC34-80-unknown	MFITPA...	80		inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt196656
Q8VC34-80-unknown	MFITPA...	80		inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt196655
Q8VC34-80-unknown	MFITPA...	80		inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt196657
Q8VC34-80-unknown	MFITPA...	80		inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt196658

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...AVRIVE	62	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSMUSP00000121306
...AVRIVE	62	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt153939
...AVRIVE	62	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt153940
...VLLLLL	568	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt83733
...VLLLLL	568	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt83732
...VLLLLL	568	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSMUSP00000108269
...VLLLLL	568	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSMUSP00000108273
...VLLLLL	568	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt92923
...VLLLLL	568	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt92924
...FRTSC	614	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...FRTSC	614	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt83734

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)