TopFIND 4.0

Q8VCM8: Nicalin

General Information

Protein names
- Nicalin
- Nicastrin-like protein
Gene names Ncln
Organism Mus musculus
Protease Family
Protease ID M28.978
Chromosome location
UniProt ID Q8VCM8

2

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MLEEAGEVLE NVLKASCLPL GFIVFLPAVL LLVAPPLPAA DAAHEFTVYR MQQYDLQGQP 
        70         80         90        100        110        120 
YGTRNAVLNT EARTVDADVL SRRCVLMRLL DFSYEHYQKA LRQSAGAVVI ILPRAMAAVP 
       130        140        150        160        170        180 
QDVVRQFMEI EPEMLAMETV VPVYFAVEDE ALLSIYEQTQ AASASQGSAS AAEVLLHTAT 
       190        200        210        220        230        240 
ANGFQMVTSG AQSQAVSDWL ITSVEGRLTG LGGEDLPTIV IVAHYDAFGV APWLSLGADS 
       250        260        270        280        290        300 
NGSGISVLLE LARLFSRLYT YKRTHAAYNL LFFASGGGKF NYQGTKRWLE DSLDHTDSSL 
       310        320        330        340        350        360 
LQDNVAFVLC LDTVGRGSHL RLHVSKPPRE GTLQHAFLRE LETVAAHQFP DVSFSMVHKK 
       370        380        390        400        410        420 
INLADDVLAW EHERFAIRRL PAFTLSHLES HRAGPRSSIM DVRSRVDSKT LTRNTRIIAE 
       430        440        450        460        470        480 
ALTRVIYNLT EKGTPPDMPV FTEQMQVQEE QIDSVMDWLT NQPRAAQLLD KDGTFLSTLE 
       490        500        510        520        530        540 
HFLSRYLKDV RQHHVKADKR DPEFVFYDQL KQVMNAYRVK PAIFDLLLAL CIGAYLGMAY 
       550        560    
TAVQHFHVLY KTVQRLLLKA KAQ

Isoforms



Sequence View



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Protease Assignment Confidence:


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Protein Neighborhood

Domains & Features

2 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...KAKAQ 563 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)