Q8WTS1: 1-acylglycerol-3-phosphate O-acyltransferase ABHD5 {ECO:0000305}

General Information

Protein names	- 1-acylglycerol-3-phosphate O-acyltransferase ABHD5 {ECO:0000305} - 2.3.1.51 {ECO:0000269\|PubMed:18606822} - Abhydrolase domain-containing protein 5 - Lipid droplet-binding protein CGI-58
Gene names	ABHD5
Organism	Homo sapiens
Protease Family
Protease ID	S33.975
Chromosome location
UniProt ID	Q8WTS1

4 N-termini

3 C-termini

0 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MAAEEEEVDS ADTGERSGWL TGWLPTWCPT SISHLKEAEE KMLKCVPCTY KKEPVRISNG
        70         80         90        100        110        120
NKIWTLKFSH NISNKTPLVL LHGFGGGLGL WALNFGDLCT NRPVYAFDLL GFGRSSRPRF
       130        140        150        160        170        180
DSDAEEVENQ FVESIEEWRC ALGLDKMILL GHNLGGFLAA AYSLKYPSRV NHLILVEPWG
       190        200        210        220        230        240
FPERPDLADQ DRPIPVWIRA LGAALTPFNP LAGLRIAGPF GLSLVQRLRP DFKRKYSSMF
       250        260        270        280        290        300
EDDTVTEYIY HCNVQTPSGE TAFKNMTIPY GWAKRPMLQR IGKMHPDIPV SVIFGARSCI
       310        320        330        340
DGNSGTSIQS LRPHSYVKTI AILGAGHYVY ADQPEEFNQK VKEICDTVD

Isoforms

Sequence View

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Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

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Protein Neighborhood

Domains & Features

4 N-termini - 3 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
Q8WTS1-2-unknown	MAAEEE...	1		inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q8WTS1-2-Acetylation	AAEEEE...	2	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q8WTS1-2-Acetylation	AAEEEE...	2	acetylation-		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345
Q8WTS1-2-Acetylation	AAEEEE...	2	acetylation-		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345
Q8WTS1-42-unknown	MLKCVP...	42		inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000391582
Q8WTS1-42-unknown	MLKCVP...	42		inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000412014
Q8WTS1-169-unknown	RVNHLI...	169		inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000392159

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...HGFGGG	86	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000412014
...SLKYPS	167	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000391582
...CDTVD	349	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)