Q8WUY3: Protein prune homolog 2
| Protein names | - Protein prune homolog 2 - BNIP2 motif-containing molecule at the C-terminal region 1 |
|---|---|
| Gene names | PRUNE2 |
| Organism | Homo sapiens |
| Protease Family | |
| Protease ID | |
| Chromosome location | |
| UniProt ID | Q8WUY3 |
2
N-termini
1
C-termini
0
Cleavages
0
Substrates
Sequence
10 20 30 40 50 60
MEEFLQRAKS KLNRSKRLEK VHVVIGPKSC DLDSLISTFT YAYFLDKVSP PGVLCLPVLN
70 80 90 100 110 120
IPRTEFNYFT ETRFILEELN ISESFHIFRD EINLHQLNDE GKLSITLVGS SVLASEDKTL
130 140 150 160 170 180
ESAVVKVINP VEQSDANVEF RESSSSLVLK EILQEAPELI TEQLAHRLRG SILFKWMTME
190 200 210 220 230 240
SEKISEKQEE ILSILEEKFP NLPPREDIIN VLQETQFSAQ GLSIEQTMLK DLKELSDGEI
250 260 270 280 290 300
KVAISTVSMN LENCLFHSNI TSDLKAFTDK FGFDVLILFS SYLSEEQQPR RQIAVYSENM
310 320 330 340 350 360
ELCSQICCEL EECQNPCLEL EPFDCGCDEI LVYQQEDPSV TCDQVVLVVK EVINRRCPEM
370 380 390 400 410 420
VSNSRTSSTE AVAGSAPLSQ GSSGIMELYG SDIEPQPSSV NFIENPPDLN DSNQAQVDAN
430 440 450 460 470 480
VDLVSPDSGL ATIRSSRSSK ESSVFLSDDS PVGEGAGPHH TLLPGLDSYS PIPEGAVAEE
490 500 510 520 530 540
HAWSGEHGEH FDLFNFDPAP MASGQSQQSS HSADYSPADD FFPNSDLSEG QLPAGPEGLD
550 560 570 580 590 600
GMGTNMSNYS SSSLLSGAGK DSLVEHDEEF VQRQDSPRDN SERNLSLTDF VGDESPSPER
610 620 630 640 650 660
LKNTGKRIPP TPMNSLVESS PSTEEPASLY TEDMTQKATD TGHMGPPQTH ARCSSWWGGL
670 680 690 700 710 720
EIDSKNIADA WSSSEQESVF QSPESWKEHK PSSIDRRASD SVFQPKSLEF TKSGPWESEF
730 740 750 760 770 780
GQPELGSNDI QDKNEESLPF QNLPMEKSPL PNTSPQGTNH LIEDFASLWH SGRSPTAMPE
790 800 810 820 830 840
PWGNPTDDGE PAAVAPFPAW SAFGKEDHDE ALKNTWNLHP TSSKTPSVRD PNEWAMAKSG
850 860 870 880 890 900
FAFSSSELLD NSPSEINNEA APEIWGKKNN DSRDHIFAPG NPSSDLDHTW TNSKPPKEDQ
910 920 930 940 950 960
NGLVDPKTRG KVYEKVDSWN LFEENMKKGG SDVLVPWEDS FLSYKCSDYS ASNLGEDSVP
970 980 990 1000 1010 1020
SPLDTNYSTS DSYTSPTFAG DEKETEHKPF AKEEGFESKD GNSTAEETDI PPQSLQQSSR
1030 1040 1050 1060 1070 1080
NRISSGPGNL DMWASPHTDN SSEINTTHNL DENELKTEHT DGKNISMEDD VGESSQSSYD
1090 1100 1110 1120 1130 1140
DPSMMQLYNE TNRQLTLLHS STNSRQTAPD SLDLWNRVIL EDTQSTATIS DMDNDLDWDD
1150 1160 1170 1180 1190 1200
CSGGAAIPSD GQTEGYMAEG SEPETRFTVR QLEPWGLEYQ EANQVDWELP ASDEHTKDSA
1210 1220 1230 1240 1250 1260
PSEHHTLNEK SGQLIANSIW DSVMRDKDMS SFMLPGSSHI TDSEQRELPP EIPSHSANVK
1270 1280 1290 1300 1310 1320
DTHSPDAPAA SGTSESEALI SHLDKQDTER ETLQSDAASL ATRLENPGYF PHPDPWKGHG
1330 1340 1350 1360 1370 1380
DGQSESEKEA QGATDRGHLD EEEVIASGVE NASGISEKGQ SDQELSSLVA SEHQEICIKS
1390 1400 1410 1420 1430 1440
GKISSLAVTF SPQTEEPEEV LEYEEGSYNL DSRDVQTGMS ADNLQPKDTH EKHLMSQRNS
1450 1460 1470 1480 1490 1500
GETTETSDGM NFTKYVSVPE KDLEKTEECN FLEPENVGGG PPHRVPRSLD FGDVPIDSDV
1510 1520 1530 1540 1550 1560
HVSSTCSEIT KNLDVKGSEN SLPGAGSSGN FDRDTISSEY THSSASSPEL NDSSVALSSW
1570 1580 1590 1600 1610 1620
GQQPSSGYQE ENQGNWSEQN HQESELITTD GQVEIVTKVK DLEKNRINEF EKSFDRKTPT
1630 1640 1650 1660 1670 1680
FLEIWNDSVD GDSFSSLSSP ETGKYSEHSG THQESNLIAS YQEKNEHDIS ATVQPEDARV
1690 1700 1710 1720 1730 1740
ISTSSGSDDD SVGGEESIEE EIQVANCHVA EDESRAWDSL NESNKFLVTA DPKSENIYDY
1750 1760 1770 1780 1790 1800
LDSSEPAENE NKSNPFCDNQ QSSPDPWTFS PLTETEMQIT AVEKEKRSSP ETGTTGDVAW
1810 1820 1830 1840 1850 1860
QISPKASFPK NEDNSQLEML GFSADSTEWW KASPQEGRLI ESPFERELSD SSGVLEINSS
1870 1880 1890 1900 1910 1920
VHQNASPWGV PVQGDIEPVE THYTNPFSDN HQSPFLEGNG KNSHEQLWNI QPRQPDPDAD
1930 1940 1950 1960 1970 1980
KFSQLVKLDQ IKEKDSREQT FVSAAGDELT PETPTQEQCQ DTMLPVCDHP DTAFTHAEEN
1990 2000 2010 2020 2030 2040
SCVTSNVSTN EGQETNQWEQ EKSYLGEMTN SSIATENFPA VSSPTQLIMK PGSEWDGSTP
2050 2060 2070 2080 2090 2100
SEDSRGTFVP DILHGNFQEG GQLASAAPDL WIDAKKPFSL KADGENPDIL THCEHDSNSQ
2110 2120 2130 2140 2150 2160
ASDSPDICHD SEAKQETEKH LSACMGPEVE SSELCLTEPE IDEEPIYEPG REFVPSNAEL
2170 2180 2190 2200 2210 2220
DSENATVLPP IGYQADIKGS SQPASHKGSP EPSEINGDNS TGLQVSEKGA SPDMAPILEP
2230 2240 2250 2260 2270 2280
VDRRIPRIEN VATSIFVTHQ EPTPEGDGSW ISDSFSPESQ PGARALFDGD PHLSTENPAL
2290 2300 2310 2320 2330 2340
VPDALLASDT CLDISEAAFD HSFSDASGLN TSTGTIDDMS KLTLSEGHPE TPVDGDLGKQ
2350 2360 2370 2380 2390 2400
DICSSEASWG DFEYDVMGQN IDEDLLREPE HFLYGGDPPL EEDSLKQSLA PYTPPFDLSY
2410 2420 2430 2440 2450 2460
LTEPAQSAET IEEAGSPEDE SLGCRAAEIV LSALPDRRSE GNQAETKNRL PGSQLAVLHI
2470 2480 2490 2500 2510 2520
REDPESVYLP VGAGSNILSP SNVDWEVETD NSDLPAGGDI GPPNGASKEI SELEEEKTIP
2530 2540 2550 2560 2570 2580
TKEPEQIKSE YKEERCTEKN EDRHALHMDY ILVNREENSH SKPETCEERE SIAELELYVG
2590 2600 2610 2620 2630 2640
SKETGLQGTQ LASFPDTCQP ASLNERKGLS AEKMSSKSDT RSSFESPAQD QSWMFLGHSE
2650 2660 2670 2680 2690 2700
VGDPSLDARD SGPGWSGKTV EPFSELGLGE GPQLQILEEM KPLESLALEE ASGPVSQSQK
2710 2720 2730 2740 2750 2760
SKSRGRAGPD AVTLQAVTHD NEWEMLSPQP VQKNMIPDTE MEEETEFLEL GTRISRPNGL
2770 2780 2790 2800 2810 2820
LSEDVGMDIP FEEGVLSPSA ADMRPEPPNS LDLNDTHPRR IKLTAPNINL SLDQSEGSIL
2830 2840 2850 2860 2870 2880
SDDNLDSPDE IDINVDELDT PDEADSFEYT GHDPTANKDS GQESESIPEY TAEEEREDNR
2890 2900 2910 2920 2930 2940
LWRTVVIGEQ EQRIDMKVIE PYRRVISHGG YYGDGLNAII VFAACFLPDS SRADYHYVME
2950 2960 2970 2980 2990 3000
NLFLYVISTL ELMVAEDYMI VYLNGATPRR RMPGLGWMKK CYQMIDRRLR KNLKSFIIVH
3010 3020 3030 3040 3050 3060
PSWFIRTILA VTRPFISSKF SSKIKYVNSL SELSGLIPMD CIHIPESIIK LDEELREASE
3070 3080
AAKTSCLYND PEMSSMEKDI DLKLKEKP
Isoforms
- Isoform 2 of Protein prune homolog 2 - Isoform 3 of Protein prune homolog 2 - Isoform 4 of Protein prune homolog 2 - Isoform 5 of Protein prune homolog 2Sequence View
10 20 30 40 50 60
MEEFLQRAKS KLNRSKRLEK VHVVIGPKSC DLDSLISTFT YAYFLDKVSP PGVLCLPVLN
70 80 90 100 110 120
IPRTEFNYFT ETRFILEELN ISESFHIFRD EINLHQLNDE GKLSITLVGS SVLASEDKTL
130 140 150 160 170 180
ESAVVKVINP VEQSDANVEF RESSSSLVLK EILQEAPELI TEQLAHRLRG SILFKWMTME
190 200 210 220 230 240
SEKISEKQEE ILSILEEKFP NLPPREDIIN VLQETQFSAQ GLSIEQTMLK DLKELSDGEI
250 260 270 280 290 300
KVAISTVSMN LENCLFHSNI TSDLKAFTDK FGFDVLILFS SYLSEEQQPR RQIAVYSENM
310 320 330 340 350 360
ELCSQICCEL EECQNPCLEL EPFDCGCDEI LVYQQEDPSV TCDQVVLVVK EVINRRCPEM
370 380 390 400 410 420
VSNSRTSSTE AVAGSAPLSQ GSSGIMELYG SDIEPQPSSV NFIENPPDLN DSNQAQVDAN
430 440 450 460 470 480
VDLVSPDSGL ATIRSSRSSK ESSVFLSDDS PVGEGAGPHH TLLPGLDSYS PIPEGAVAEE
490 500 510 520 530 540
HAWSGEHGEH FDLFNFDPAP MASGQSQQSS HSADYSPADD FFPNSDLSEG QLPAGPEGLD
550 560 570 580 590 600
GMGTNMSNYS SSSLLSGAGK DSLVEHDEEF VQRQDSPRDN SERNLSLTDF VGDESPSPER
610 620 630 640 650 660
LKNTGKRIPP TPMNSLVESS PSTEEPASLY TEDMTQKATD TGHMGPPQTH ARCSSWWGGL
670 680 690 700 710 720
EIDSKNIADA WSSSEQESVF QSPESWKEHK PSSIDRRASD SVFQPKSLEF TKSGPWESEF
730 740 750 760 770 780
GQPELGSNDI QDKNEESLPF QNLPMEKSPL PNTSPQGTNH LIEDFASLWH SGRSPTAMPE
790 800 810 820 830 840
PWGNPTDDGE PAAVAPFPAW SAFGKEDHDE ALKNTWNLHP TSSKTPSVRD PNEWAMAKSG
850 860 870 880 890 900
FAFSSSELLD NSPSEINNEA APEIWGKKNN DSRDHIFAPG NPSSDLDHTW TNSKPPKEDQ
910 920 930 940 950 960
NGLVDPKTRG KVYEKVDSWN LFEENMKKGG SDVLVPWEDS FLSYKCSDYS ASNLGEDSVP
970 980 990 1000 1010 1020
SPLDTNYSTS DSYTSPTFAG DEKETEHKPF AKEEGFESKD GNSTAEETDI PPQSLQQSSR
1030 1040 1050 1060 1070 1080
NRISSGPGNL DMWASPHTDN SSEINTTHNL DENELKTEHT DGKNISMEDD VGESSQSSYD
1090 1100 1110 1120 1130 1140
DPSMMQLYNE TNRQLTLLHS STNSRQTAPD SLDLWNRVIL EDTQSTATIS DMDNDLDWDD
1150 1160 1170 1180 1190 1200
CSGGAAIPSD GQTEGYMAEG SEPETRFTVR QLEPWGLEYQ EANQVDWELP ASDEHTKDSA
1210 1220 1230 1240 1250 1260
PSEHHTLNEK SGQLIANSIW DSVMRDKDMS SFMLPGSSHI TDSEQRELPP EIPSHSANVK
1270 1280 1290 1300 1310 1320
DTHSPDAPAA SGTSESEALI SHLDKQDTER ETLQSDAASL ATRLENPGYF PHPDPWKGHG
1330 1340 1350 1360 1370 1380
DGQSESEKEA QGATDRGHLD EEEVIASGVE NASGISEKGQ SDQELSSLVA SEHQEICIKS
1390 1400 1410 1420 1430 1440
GKISSLAVTF SPQTEEPEEV LEYEEGSYNL DSRDVQTGMS ADNLQPKDTH EKHLMSQRNS
1450 1460 1470 1480 1490 1500
GETTETSDGM NFTKYVSVPE KDLEKTEECN FLEPENVGGG PPHRVPRSLD FGDVPIDSDV
1510 1520 1530 1540 1550 1560
HVSSTCSEIT KNLDVKGSEN SLPGAGSSGN FDRDTISSEY THSSASSPEL NDSSVALSSW
1570 1580 1590 1600 1610 1620
GQQPSSGYQE ENQGNWSEQN HQESELITTD GQVEIVTKVK DLEKNRINEF EKSFDRKTPT
1630 1640 1650 1660 1670 1680
FLEIWNDSVD GDSFSSLSSP ETGKYSEHSG THQESNLIAS YQEKNEHDIS ATVQPEDARV
1690 1700 1710 1720 1730 1740
ISTSSGSDDD SVGGEESIEE EIQVANCHVA EDESRAWDSL NESNKFLVTA DPKSENIYDY
1750 1760 1770 1780 1790 1800
LDSSEPAENE NKSNPFCDNQ QSSPDPWTFS PLTETEMQIT AVEKEKRSSP ETGTTGDVAW
1810 1820 1830 1840 1850 1860
QISPKASFPK NEDNSQLEML GFSADSTEWW KASPQEGRLI ESPFERELSD SSGVLEINSS
1870 1880 1890 1900 1910 1920
VHQNASPWGV PVQGDIEPVE THYTNPFSDN HQSPFLEGNG KNSHEQLWNI QPRQPDPDAD
1930 1940 1950 1960 1970 1980
KFSQLVKLDQ IKEKDSREQT FVSAAGDELT PETPTQEQCQ DTMLPVCDHP DTAFTHAEEN
1990 2000 2010 2020 2030 2040
SCVTSNVSTN EGQETNQWEQ EKSYLGEMTN SSIATENFPA VSSPTQLIMK PGSEWDGSTP
2050 2060 2070 2080 2090 2100
SEDSRGTFVP DILHGNFQEG GQLASAAPDL WIDAKKPFSL KADGENPDIL THCEHDSNSQ
2110 2120 2130 2140 2150 2160
ASDSPDICHD SEAKQETEKH LSACMGPEVE SSELCLTEPE IDEEPIYEPG REFVPSNAEL
2170 2180 2190 2200 2210 2220
DSENATVLPP IGYQADIKGS SQPASHKGSP EPSEINGDNS TGLQVSEKGA SPDMAPILEP
2230 2240 2250 2260 2270 2280
VDRRIPRIEN VATSIFVTHQ EPTPEGDGSW ISDSFSPESQ PGARALFDGD PHLSTENPAL
2290 2300 2310 2320 2330 2340
VPDALLASDT CLDISEAAFD HSFSDASGLN TSTGTIDDMS KLTLSEGHPE TPVDGDLGKQ
2350 2360 2370 2380 2390 2400
DICSSEASWG DFEYDVMGQN IDEDLLREPE HFLYGGDPPL EEDSLKQSLA PYTPPFDLSY
2410 2420 2430 2440 2450 2460
LTEPAQSAET IEEAGSPEDE SLGCRAAEIV LSALPDRRSE GNQAETKNRL PGSQLAVLHI
2470 2480 2490 2500 2510 2520
REDPESVYLP VGAGSNILSP SNVDWEVETD NSDLPAGGDI GPPNGASKEI SELEEEKTIP
2530 2540 2550 2560 2570 2580
TKEPEQIKSE YKEERCTEKN EDRHALHMDY ILVNREENSH SKPETCEERE SIAELELYVG
2590 2600 2610 2620 2630 2640
SKETGLQGTQ LASFPDTCQP ASLNERKGLS AEKMSSKSDT RSSFESPAQD QSWMFLGHSE
2650 2660 2670 2680 2690 2700
VGDPSLDARD SGPGWSGKTV EPFSELGLGE GPQLQILEEM KPLESLALEE ASGPVSQSQK
2710 2720 2730 2740 2750 2760
SKSRGRAGPD AVTLQAVTHD NEWEMLSPQP VQKNMIPDTE MEEETEFLEL GTRISRPNGL
2770 2780 2790 2800 2810 2820
LSEDVGMDIP FEEGVLSPSA ADMRPEPPNS LDLNDTHPRR IKLTAPNINL SLDQSEGSIL
2830 2840 2850 2860 2870 2880
SDDNLDSPDE IDINVDELDT PDEADSFEYT GHDPTANKDS GQESESIPEY TAEEEREDNR
2890 2900 2910 2920 2930 2940
LWRTVVIGEQ EQRIDMKVIE PYRRVISHGG YYGDGLNAII VFAACFLPDS SRADYHYVME
2950 2960 2970 2980 2990 3000
NLFLYVISTL ELMVAEDYMI VYLNGATPRR RMPGLGWMKK CYQMIDRRLR KNLKSFIIVH
3010 3020 3030 3040 3050 3060
PSWFIRTILA VTRPFISSKF SSKIKYVNSL SELSGLIPMD CIHIPESIIK LDEELREASE
3070 3080
AAKTSCLYND PEMSSMEKDI DLKLKEKP
10 20 30 40 50 60
MEEFLQRAKS KLNRSKRLEK VHVVIGPKSC DLDSLISTFT YAYFLDKVSP PGVLCLPVLN
70 80 90 100 110 120
IPRTEFNYFT ETRFILEELN ISESFHIFRD EINLHQLNDE GKLSITLVGS SVLASEDKTL
130 140 150 160 170 180
ESAVVKVINP VEQSDANVEF RESSSSLVLK EILQEAPELI TEQLAHRLRG SILFKWMTME
190 200 210 220 230 240
SEKISEKQEE ILSILEEKFP NLPPREDIIN VLQETQFSAQ GLSIEQTMLK DLKELSDGEI
250 260 270 280 290 300
KVAISTVSMN LENCLFHSNI TSDLKAFTDK FGFDVLILFS SYLSEEQQPR RQIAVYSENM
310 320 330 340 350 360
ELCSQICCEL EECQNPCLEL EPFDCGCDEI LVYQQEDPSV TCDQVVLVVK EVINRRCPEM
370 380 390 400 410 420
VSNSRTSSTE AVAGSAPLSQ GSSGIMELYG SDIEPQPSSV NFIENPPDLN DSNQAQVDAN
430 440 450 460 470 480
VDLVSPDSGL ATIRSSRSSK ESSVFLSDDS PVGEGAGPHH TLLPGLDSYS PIPEGAVAEE
490 500 510 520 530 540
HAWSGEHGEH FDLFNFDPAP MASGQSQQSS HSADYSPADD FFPNSDLSEG QLPAGPEGLD
550 560 570 580 590 600
GMGTNMSNYS SSSLLSGAGK DSLVEHDEEF VQRQDSPRDN SERNLSLTDF VGDESPSPER
610 620 630 640 650 660
LKNTGKRIPP TPMNSLVESS PSTEEPASLY TEDMTQKATD TGHMGPPQTH ARCSSWWGGL
670 680 690 700 710 720
EIDSKNIADA WSSSEQESVF QSPESWKEHK PSSIDRRASD SVFQPKSLEF TKSGPWESEF
730 740 750 760 770 780
GQPELGSNDI QDKNEESLPF QNLPMEKSPL PNTSPQGTNH LIEDFASLWH SGRSPTAMPE
790 800 810 820 830 840
PWGNPTDDGE PAAVAPFPAW SAFGKEDHDE ALKNTWNLHP TSSKTPSVRD PNEWAMAKSG
850 860 870 880 890 900
FAFSSSELLD NSPSEINNEA APEIWGKKNN DSRDHIFAPG NPSSDLDHTW TNSKPPKEDQ
910 920 930 940 950 960
NGLVDPKTRG KVYEKVDSWN LFEENMKKGG SDVLVPWEDS FLSYKCSDYS ASNLGEDSVP
970 980 990 1000 1010 1020
SPLDTNYSTS DSYTSPTFAG DEKETEHKPF AKEEGFESKD GNSTAEETDI PPQSLQQSSR
1030 1040 1050 1060 1070 1080
NRISSGPGNL DMWASPHTDN SSEINTTHNL DENELKTEHT DGKNISMEDD VGESSQSSYD
1090 1100 1110 1120 1130 1140
DPSMMQLYNE TNRQLTLLHS STNSRQTAPD SLDLWNRVIL EDTQSTATIS DMDNDLDWDD
1150 1160 1170 1180 1190 1200
CSGGAAIPSD GQTEGYMAEG SEPETRFTVR QLEPWGLEYQ EANQVDWELP ASDEHTKDSA
1210 1220 1230 1240 1250 1260
PSEHHTLNEK SGQLIANSIW DSVMRDKDMS SFMLPGSSHI TDSEQRELPP EIPSHSANVK
1270 1280 1290 1300 1310 1320
DTHSPDAPAA SGTSESEALI SHLDKQDTER ETLQSDAASL ATRLENPGYF PHPDPWKGHG
1330 1340 1350 1360 1370 1380
DGQSESEKEA QGATDRGHLD EEEVIASGVE NASGISEKGQ SDQELSSLVA SEHQEICIKS
1390 1400 1410 1420 1430 1440
GKISSLAVTF SPQTEEPEEV LEYEEGSYNL DSRDVQTGMS ADNLQPKDTH EKHLMSQRNS
1450 1460 1470 1480 1490 1500
GETTETSDGM NFTKYVSVPE KDLEKTEECN FLEPENVGGG PPHRVPRSLD FGDVPIDSDV
1510 1520 1530 1540 1550 1560
HVSSTCSEIT KNLDVKGSEN SLPGAGSSGN FDRDTISSEY THSSASSPEL NDSSVALSSW
1570 1580 1590 1600 1610 1620
GQQPSSGYQE ENQGNWSEQN HQESELITTD GQVEIVTKVK DLEKNRINEF EKSFDRKTPT
1630 1640 1650 1660 1670 1680
FLEIWNDSVD GDSFSSLSSP ETGKYSEHSG THQESNLIAS YQEKNEHDIS ATVQPEDARV
1690 1700 1710 1720 1730 1740
ISTSSGSDDD SVGGEESIEE EIQVANCHVA EDESRAWDSL NESNKFLVTA DPKSENIYDY
1750 1760 1770 1780 1790 1800
LDSSEPAENE NKSNPFCDNQ QSSPDPWTFS PLTETEMQIT AVEKEKRSSP ETGTTGDVAW
1810 1820 1830 1840 1850 1860
QISPKASFPK NEDNSQLEML GFSADSTEWW KASPQEGRLI ESPFERELSD SSGVLEINSS
1870 1880 1890 1900 1910 1920
VHQNASPWGV PVQGDIEPVE THYTNPFSDN HQSPFLEGNG KNSHEQLWNI QPRQPDPDAD
1930 1940 1950 1960 1970 1980
KFSQLVKLDQ IKEKDSREQT FVSAAGDELT PETPTQEQCQ DTMLPVCDHP DTAFTHAEEN
1990 2000 2010 2020 2030 2040
SCVTSNVSTN EGQETNQWEQ EKSYLGEMTN SSIATENFPA VSSPTQLIMK PGSEWDGSTP
2050 2060 2070 2080 2090 2100
SEDSRGTFVP DILHGNFQEG GQLASAAPDL WIDAKKPFSL KADGENPDIL THCEHDSNSQ
2110 2120 2130 2140 2150 2160
ASDSPDICHD SEAKQETEKH LSACMGPEVE SSELCLTEPE IDEEPIYEPG REFVPSNAEL
2170 2180 2190 2200 2210 2220
DSENATVLPP IGYQADIKGS SQPASHKGSP EPSEINGDNS TGLQVSEKGA SPDMAPILEP
2230 2240 2250 2260 2270 2280
VDRRIPRIEN VATSIFVTHQ EPTPEGDGSW ISDSFSPESQ PGARALFDGD PHLSTENPAL
2290 2300 2310 2320 2330 2340
VPDALLASDT CLDISEAAFD HSFSDASGLN TSTGTIDDMS KLTLSEGHPE TPVDGDLGKQ
2350 2360 2370 2380 2390 2400
DICSSEASWG DFEYDVMGQN IDEDLLREPE HFLYGGDPPL EEDSLKQSLA PYTPPFDLSY
2410 2420 2430 2440 2450 2460
LTEPAQSAET IEEAGSPEDE SLGCRAAEIV LSALPDRRSE GNQAETKNRL PGSQLAVLHI
2470 2480 2490 2500 2510 2520
REDPESVYLP VGAGSNILSP SNVDWEVETD NSDLPAGGDI GPPNGASKEI SELEEEKTIP
2530 2540 2550 2560 2570 2580
TKEPEQIKSE YKEERCTEKN EDRHALHMDY ILVNREENSH SKPETCEERE SIAELELYVG
2590 2600 2610 2620 2630 2640
SKETGLQGTQ LASFPDTCQP ASLNERKGLS AEKMSSKSDT RSSFESPAQD QSWMFLGHSE
2650 2660 2670 2680 2690 2700
VGDPSLDARD SGPGWSGKTV EPFSELGLGE GPQLQILEEM KPLESLALEE ASGPVSQSQK
2710 2720 2730 2740 2750 2760
SKSRGRAGPD AVTLQAVTHD NEWEMLSPQP VQKNMIPDTE MEEETEFLEL GTRISRPNGL
2770 2780 2790 2800 2810 2820
LSEDVGMDIP FEEGVLSPSA ADMRPEPPNS LDLNDTHPRR IKLTAPNINL SLDQSEGSIL
2830 2840 2850 2860 2870 2880
SDDNLDSPDE IDINVDELDT PDEADSFEYT GHDPTANKDS GQESESIPEY TAEEEREDNR
2890 2900 2910 2920 2930 2940
LWRTVVIGEQ EQRIDMKVIE PYRRVISHGG YYGDGLNAII VFAACFLPDS SRADYHYVME
2950 2960 2970 2980 2990 3000
NLFLYVISTL ELMVAEDYMI VYLNGATPRR RMPGLGWMKK CYQMIDRRLR KNLKSFIIVH
3010 3020 3030 3040 3050 3060
PSWFIRTILA VTRPFISSKF SSKIKYVNSL SELSGLIPMD CIHIPESIIK LDEELREASE
3070 3080
AAKTSCLYND PEMSSMEKDI DLKLKEKP
10 20 30 40 50 60
MEEFLQRAKS KLNRSKRLEK VHVVIGPKSC DLDSLISTFT YAYFLDKVSP PGVLCLPVLN
70 80 90 100 110 120
IPRTEFNYFT ETRFILEELN ISESFHIFRD EINLHQLNDE GKLSITLVGS SVLASEDKTL
130 140 150 160 170 180
ESAVVKVINP VEQSDANVEF RESSSSLVLK EILQEAPELI TEQLAHRLRG SILFKWMTME
190 200 210 220 230 240
SEKISEKQEE ILSILEEKFP NLPPREDIIN VLQETQFSAQ GLSIEQTMLK DLKELSDGEI
250 260 270 280 290 300
KVAISTVSMN LENCLFHSNI TSDLKAFTDK FGFDVLILFS SYLSEEQQPR RQIAVYSENM
310 320 330 340 350 360
ELCSQICCEL EECQNPCLEL EPFDCGCDEI LVYQQEDPSV TCDQVVLVVK EVINRRCPEM
370 380 390 400 410 420
VSNSRTSSTE AVAGSAPLSQ GSSGIMELYG SDIEPQPSSV NFIENPPDLN DSNQAQVDAN
430 440 450 460 470 480
VDLVSPDSGL ATIRSSRSSK ESSVFLSDDS PVGEGAGPHH TLLPGLDSYS PIPEGAVAEE
490 500 510 520 530 540
HAWSGEHGEH FDLFNFDPAP MASGQSQQSS HSADYSPADD FFPNSDLSEG QLPAGPEGLD
550 560 570 580 590 600
GMGTNMSNYS SSSLLSGAGK DSLVEHDEEF VQRQDSPRDN SERNLSLTDF VGDESPSPER
610 620 630 640 650 660
LKNTGKRIPP TPMNSLVESS PSTEEPASLY TEDMTQKATD TGHMGPPQTH ARCSSWWGGL
670 680 690 700 710 720
EIDSKNIADA WSSSEQESVF QSPESWKEHK PSSIDRRASD SVFQPKSLEF TKSGPWESEF
730 740 750 760 770 780
GQPELGSNDI QDKNEESLPF QNLPMEKSPL PNTSPQGTNH LIEDFASLWH SGRSPTAMPE
790 800 810 820 830 840
PWGNPTDDGE PAAVAPFPAW SAFGKEDHDE ALKNTWNLHP TSSKTPSVRD PNEWAMAKSG
850 860 870 880 890 900
FAFSSSELLD NSPSEINNEA APEIWGKKNN DSRDHIFAPG NPSSDLDHTW TNSKPPKEDQ
910 920 930 940 950 960
NGLVDPKTRG KVYEKVDSWN LFEENMKKGG SDVLVPWEDS FLSYKCSDYS ASNLGEDSVP
970 980 990 1000 1010 1020
SPLDTNYSTS DSYTSPTFAG DEKETEHKPF AKEEGFESKD GNSTAEETDI PPQSLQQSSR
1030 1040 1050 1060 1070 1080
NRISSGPGNL DMWASPHTDN SSEINTTHNL DENELKTEHT DGKNISMEDD VGESSQSSYD
1090 1100 1110 1120 1130 1140
DPSMMQLYNE TNRQLTLLHS STNSRQTAPD SLDLWNRVIL EDTQSTATIS DMDNDLDWDD
1150 1160 1170 1180 1190 1200
CSGGAAIPSD GQTEGYMAEG SEPETRFTVR QLEPWGLEYQ EANQVDWELP ASDEHTKDSA
1210 1220 1230 1240 1250 1260
PSEHHTLNEK SGQLIANSIW DSVMRDKDMS SFMLPGSSHI TDSEQRELPP EIPSHSANVK
1270 1280 1290 1300 1310 1320
DTHSPDAPAA SGTSESEALI SHLDKQDTER ETLQSDAASL ATRLENPGYF PHPDPWKGHG
1330 1340 1350 1360 1370 1380
DGQSESEKEA QGATDRGHLD EEEVIASGVE NASGISEKGQ SDQELSSLVA SEHQEICIKS
1390 1400 1410 1420 1430 1440
GKISSLAVTF SPQTEEPEEV LEYEEGSYNL DSRDVQTGMS ADNLQPKDTH EKHLMSQRNS
1450 1460 1470 1480 1490 1500
GETTETSDGM NFTKYVSVPE KDLEKTEECN FLEPENVGGG PPHRVPRSLD FGDVPIDSDV
1510 1520 1530 1540 1550 1560
HVSSTCSEIT KNLDVKGSEN SLPGAGSSGN FDRDTISSEY THSSASSPEL NDSSVALSSW
1570 1580 1590 1600 1610 1620
GQQPSSGYQE ENQGNWSEQN HQESELITTD GQVEIVTKVK DLEKNRINEF EKSFDRKTPT
1630 1640 1650 1660 1670 1680
FLEIWNDSVD GDSFSSLSSP ETGKYSEHSG THQESNLIAS YQEKNEHDIS ATVQPEDARV
1690 1700 1710 1720 1730 1740
ISTSSGSDDD SVGGEESIEE EIQVANCHVA EDESRAWDSL NESNKFLVTA DPKSENIYDY
1750 1760 1770 1780 1790 1800
LDSSEPAENE NKSNPFCDNQ QSSPDPWTFS PLTETEMQIT AVEKEKRSSP ETGTTGDVAW
1810 1820 1830 1840 1850 1860
QISPKASFPK NEDNSQLEML GFSADSTEWW KASPQEGRLI ESPFERELSD SSGVLEINSS
1870 1880 1890 1900 1910 1920
VHQNASPWGV PVQGDIEPVE THYTNPFSDN HQSPFLEGNG KNSHEQLWNI QPRQPDPDAD
1930 1940 1950 1960 1970 1980
KFSQLVKLDQ IKEKDSREQT FVSAAGDELT PETPTQEQCQ DTMLPVCDHP DTAFTHAEEN
1990 2000 2010 2020 2030 2040
SCVTSNVSTN EGQETNQWEQ EKSYLGEMTN SSIATENFPA VSSPTQLIMK PGSEWDGSTP
2050 2060 2070 2080 2090 2100
SEDSRGTFVP DILHGNFQEG GQLASAAPDL WIDAKKPFSL KADGENPDIL THCEHDSNSQ
2110 2120 2130 2140 2150 2160
ASDSPDICHD SEAKQETEKH LSACMGPEVE SSELCLTEPE IDEEPIYEPG REFVPSNAEL
2170 2180 2190 2200 2210 2220
DSENATVLPP IGYQADIKGS SQPASHKGSP EPSEINGDNS TGLQVSEKGA SPDMAPILEP
2230 2240 2250 2260 2270 2280
VDRRIPRIEN VATSIFVTHQ EPTPEGDGSW ISDSFSPESQ PGARALFDGD PHLSTENPAL
2290 2300 2310 2320 2330 2340
VPDALLASDT CLDISEAAFD HSFSDASGLN TSTGTIDDMS KLTLSEGHPE TPVDGDLGKQ
2350 2360 2370 2380 2390 2400
DICSSEASWG DFEYDVMGQN IDEDLLREPE HFLYGGDPPL EEDSLKQSLA PYTPPFDLSY
2410 2420 2430 2440 2450 2460
LTEPAQSAET IEEAGSPEDE SLGCRAAEIV LSALPDRRSE GNQAETKNRL PGSQLAVLHI
2470 2480 2490 2500 2510 2520
REDPESVYLP VGAGSNILSP SNVDWEVETD NSDLPAGGDI GPPNGASKEI SELEEEKTIP
2530 2540 2550 2560 2570 2580
TKEPEQIKSE YKEERCTEKN EDRHALHMDY ILVNREENSH SKPETCEERE SIAELELYVG
2590 2600 2610 2620 2630 2640
SKETGLQGTQ LASFPDTCQP ASLNERKGLS AEKMSSKSDT RSSFESPAQD QSWMFLGHSE
2650 2660 2670 2680 2690 2700
VGDPSLDARD SGPGWSGKTV EPFSELGLGE GPQLQILEEM KPLESLALEE ASGPVSQSQK
2710 2720 2730 2740 2750 2760
SKSRGRAGPD AVTLQAVTHD NEWEMLSPQP VQKNMIPDTE MEEETEFLEL GTRISRPNGL
2770 2780 2790 2800 2810 2820
LSEDVGMDIP FEEGVLSPSA ADMRPEPPNS LDLNDTHPRR IKLTAPNINL SLDQSEGSIL
2830 2840 2850 2860 2870 2880
SDDNLDSPDE IDINVDELDT PDEADSFEYT GHDPTANKDS GQESESIPEY TAEEEREDNR
2890 2900 2910 2920 2930 2940
LWRTVVIGEQ EQRIDMKVIE PYRRVISHGG YYGDGLNAII VFAACFLPDS SRADYHYVME
2950 2960 2970 2980 2990 3000
NLFLYVISTL ELMVAEDYMI VYLNGATPRR RMPGLGWMKK CYQMIDRRLR KNLKSFIIVH
3010 3020 3030 3040 3050 3060
PSWFIRTILA VTRPFISSKF SSKIKYVNSL SELSGLIPMD CIHIPESIIK LDEELREASE
3070 3080
AAKTSCLYND PEMSSMEKDI DLKLKEKP
10 20 30 40 50 60
MEEFLQRAKS KLNRSKRLEK VHVVIGPKSC DLDSLISTFT YAYFLDKVSP PGVLCLPVLN
70 80 90 100 110 120
IPRTEFNYFT ETRFILEELN ISESFHIFRD EINLHQLNDE GKLSITLVGS SVLASEDKTL
130 140 150 160 170 180
ESAVVKVINP VEQSDANVEF RESSSSLVLK EILQEAPELI TEQLAHRLRG SILFKWMTME
190 200 210 220 230 240
SEKISEKQEE ILSILEEKFP NLPPREDIIN VLQETQFSAQ GLSIEQTMLK DLKELSDGEI
250 260 270 280 290 300
KVAISTVSMN LENCLFHSNI TSDLKAFTDK FGFDVLILFS SYLSEEQQPR RQIAVYSENM
310 320 330 340 350 360
ELCSQICCEL EECQNPCLEL EPFDCGCDEI LVYQQEDPSV TCDQVVLVVK EVINRRCPEM
370 380 390 400 410 420
VSNSRTSSTE AVAGSAPLSQ GSSGIMELYG SDIEPQPSSV NFIENPPDLN DSNQAQVDAN
430 440 450 460 470 480
VDLVSPDSGL ATIRSSRSSK ESSVFLSDDS PVGEGAGPHH TLLPGLDSYS PIPEGAVAEE
490 500 510 520 530 540
HAWSGEHGEH FDLFNFDPAP MASGQSQQSS HSADYSPADD FFPNSDLSEG QLPAGPEGLD
550 560 570 580 590 600
GMGTNMSNYS SSSLLSGAGK DSLVEHDEEF VQRQDSPRDN SERNLSLTDF VGDESPSPER
610 620 630 640 650 660
LKNTGKRIPP TPMNSLVESS PSTEEPASLY TEDMTQKATD TGHMGPPQTH ARCSSWWGGL
670 680 690 700 710 720
EIDSKNIADA WSSSEQESVF QSPESWKEHK PSSIDRRASD SVFQPKSLEF TKSGPWESEF
730 740 750 760 770 780
GQPELGSNDI QDKNEESLPF QNLPMEKSPL PNTSPQGTNH LIEDFASLWH SGRSPTAMPE
790 800 810 820 830 840
PWGNPTDDGE PAAVAPFPAW SAFGKEDHDE ALKNTWNLHP TSSKTPSVRD PNEWAMAKSG
850 860 870 880 890 900
FAFSSSELLD NSPSEINNEA APEIWGKKNN DSRDHIFAPG NPSSDLDHTW TNSKPPKEDQ
910 920 930 940 950 960
NGLVDPKTRG KVYEKVDSWN LFEENMKKGG SDVLVPWEDS FLSYKCSDYS ASNLGEDSVP
970 980 990 1000 1010 1020
SPLDTNYSTS DSYTSPTFAG DEKETEHKPF AKEEGFESKD GNSTAEETDI PPQSLQQSSR
1030 1040 1050 1060 1070 1080
NRISSGPGNL DMWASPHTDN SSEINTTHNL DENELKTEHT DGKNISMEDD VGESSQSSYD
1090 1100 1110 1120 1130 1140
DPSMMQLYNE TNRQLTLLHS STNSRQTAPD SLDLWNRVIL EDTQSTATIS DMDNDLDWDD
1150 1160 1170 1180 1190 1200
CSGGAAIPSD GQTEGYMAEG SEPETRFTVR QLEPWGLEYQ EANQVDWELP ASDEHTKDSA
1210 1220 1230 1240 1250 1260
PSEHHTLNEK SGQLIANSIW DSVMRDKDMS SFMLPGSSHI TDSEQRELPP EIPSHSANVK
1270 1280 1290 1300 1310 1320
DTHSPDAPAA SGTSESEALI SHLDKQDTER ETLQSDAASL ATRLENPGYF PHPDPWKGHG
1330 1340 1350 1360 1370 1380
DGQSESEKEA QGATDRGHLD EEEVIASGVE NASGISEKGQ SDQELSSLVA SEHQEICIKS
1390 1400 1410 1420 1430 1440
GKISSLAVTF SPQTEEPEEV LEYEEGSYNL DSRDVQTGMS ADNLQPKDTH EKHLMSQRNS
1450 1460 1470 1480 1490 1500
GETTETSDGM NFTKYVSVPE KDLEKTEECN FLEPENVGGG PPHRVPRSLD FGDVPIDSDV
1510 1520 1530 1540 1550 1560
HVSSTCSEIT KNLDVKGSEN SLPGAGSSGN FDRDTISSEY THSSASSPEL NDSSVALSSW
1570 1580 1590 1600 1610 1620
GQQPSSGYQE ENQGNWSEQN HQESELITTD GQVEIVTKVK DLEKNRINEF EKSFDRKTPT
1630 1640 1650 1660 1670 1680
FLEIWNDSVD GDSFSSLSSP ETGKYSEHSG THQESNLIAS YQEKNEHDIS ATVQPEDARV
1690 1700 1710 1720 1730 1740
ISTSSGSDDD SVGGEESIEE EIQVANCHVA EDESRAWDSL NESNKFLVTA DPKSENIYDY
1750 1760 1770 1780 1790 1800
LDSSEPAENE NKSNPFCDNQ QSSPDPWTFS PLTETEMQIT AVEKEKRSSP ETGTTGDVAW
1810 1820 1830 1840 1850 1860
QISPKASFPK NEDNSQLEML GFSADSTEWW KASPQEGRLI ESPFERELSD SSGVLEINSS
1870 1880 1890 1900 1910 1920
VHQNASPWGV PVQGDIEPVE THYTNPFSDN HQSPFLEGNG KNSHEQLWNI QPRQPDPDAD
1930 1940 1950 1960 1970 1980
KFSQLVKLDQ IKEKDSREQT FVSAAGDELT PETPTQEQCQ DTMLPVCDHP DTAFTHAEEN
1990 2000 2010 2020 2030 2040
SCVTSNVSTN EGQETNQWEQ EKSYLGEMTN SSIATENFPA VSSPTQLIMK PGSEWDGSTP
2050 2060 2070 2080 2090 2100
SEDSRGTFVP DILHGNFQEG GQLASAAPDL WIDAKKPFSL KADGENPDIL THCEHDSNSQ
2110 2120 2130 2140 2150 2160
ASDSPDICHD SEAKQETEKH LSACMGPEVE SSELCLTEPE IDEEPIYEPG REFVPSNAEL
2170 2180 2190 2200 2210 2220
DSENATVLPP IGYQADIKGS SQPASHKGSP EPSEINGDNS TGLQVSEKGA SPDMAPILEP
2230 2240 2250 2260 2270 2280
VDRRIPRIEN VATSIFVTHQ EPTPEGDGSW ISDSFSPESQ PGARALFDGD PHLSTENPAL
2290 2300 2310 2320 2330 2340
VPDALLASDT CLDISEAAFD HSFSDASGLN TSTGTIDDMS KLTLSEGHPE TPVDGDLGKQ
2350 2360 2370 2380 2390 2400
DICSSEASWG DFEYDVMGQN IDEDLLREPE HFLYGGDPPL EEDSLKQSLA PYTPPFDLSY
2410 2420 2430 2440 2450 2460
LTEPAQSAET IEEAGSPEDE SLGCRAAEIV LSALPDRRSE GNQAETKNRL PGSQLAVLHI
2470 2480 2490 2500 2510 2520
REDPESVYLP VGAGSNILSP SNVDWEVETD NSDLPAGGDI GPPNGASKEI SELEEEKTIP
2530 2540 2550 2560 2570 2580
TKEPEQIKSE YKEERCTEKN EDRHALHMDY ILVNREENSH SKPETCEERE SIAELELYVG
2590 2600 2610 2620 2630 2640
SKETGLQGTQ LASFPDTCQP ASLNERKGLS AEKMSSKSDT RSSFESPAQD QSWMFLGHSE
2650 2660 2670 2680 2690 2700
VGDPSLDARD SGPGWSGKTV EPFSELGLGE GPQLQILEEM KPLESLALEE ASGPVSQSQK
2710 2720 2730 2740 2750 2760
SKSRGRAGPD AVTLQAVTHD NEWEMLSPQP VQKNMIPDTE MEEETEFLEL GTRISRPNGL
2770 2780 2790 2800 2810 2820
LSEDVGMDIP FEEGVLSPSA ADMRPEPPNS LDLNDTHPRR IKLTAPNINL SLDQSEGSIL
2830 2840 2850 2860 2870 2880
SDDNLDSPDE IDINVDELDT PDEADSFEYT GHDPTANKDS GQESESIPEY TAEEEREDNR
2890 2900 2910 2920 2930 2940
LWRTVVIGEQ EQRIDMKVIE PYRRVISHGG YYGDGLNAII VFAACFLPDS SRADYHYVME
2950 2960 2970 2980 2990 3000
NLFLYVISTL ELMVAEDYMI VYLNGATPRR RMPGLGWMKK CYQMIDRRLR KNLKSFIIVH
3010 3020 3030 3040 3050 3060
PSWFIRTILA VTRPFISSKF SSKIKYVNSL SELSGLIPMD CIHIPESIIK LDEELREASE
3070 3080
AAKTSCLYND PEMSSMEKDI DLKLKEKP
Protein Neighborhood
Domains & Features
2 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates
N-termini
| Name | Sequence | Position | Modification | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMID) |
|---|---|---|---|---|---|---|---|---|---|
| Q8WUY3-1-Acetylation | MEEFLQ... | 1 | acetylation- | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | ||
| Q8WUY3-1-Acetylation | MEEFLQ... | 1 | acetylation- | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt103439 | ||
| Q8WUY3-1-Acetylation | MEEFLQ... | 1 | acetylation- | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt103440 | ||
| Q8WUY3-1-Acetylation | MEEFLQ... | 1 | acetylation- | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt103441 | ||
| Q8WUY3-1-unknown | MEEFLQ... | 1 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt86323 | |||
| Q8WUY3-1-unknown | MEEFLQ... | 1 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt86324 | |||
| Q8WUY3-1-unknown | MEEFLQ... | 1 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt86325 |
C-termini
| Name | Sequence | Position | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
|---|---|---|---|---|---|---|---|---|
| ...LKEKP | 3088 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
| ...LKEKP | 3088 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt81944 | |||
| ...LKEKP | 3088 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt81941 | |||
| ...LKEKP | 3088 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt81942 |
Cleavages
| Protease | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
|---|
Substrates
| Substrate | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
|---|