TopFIND 4.0

Q8WVB3: Hexosaminidase D {ECO:0000305}

General Information

Protein names
- Hexosaminidase D {ECO:0000305}
- 3.2.1.52 {ECO:0000269|PubMed:23099419}
- Beta-N-acetylhexosaminidase
- Beta-hexosaminidase D
- Hexosaminidase domain-containing protein
- N-acetyl-beta-galactosaminidase
Gene names HEXDC
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID Q8WVB3

1

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MSGSTPFQMR LVHLDLKGAP PKVSYLSEIF PLFRALGANG LLIEYEDMFP YEGPLRLLRA 
        70         80         90        100        110        120 
KYAYSPSEIK EILHLAGLNE LEVIPLVQTF GHMEFVLKHT AFAHLREVGS FPCTLNPHEA 
       130        140        150        160        170        180 
ESLALVGAMI DQVLELHPGA QRLHIGCDEV YYLGEGEASR RWLQQEQNST GKLCLSHMRA 
       190        200        210        220        230        240 
VASGVKARRP SVTPLVWDDM LRDLPEDQLA ASGVPQLVEP VLWDYTADLD VHGKVLLMQK 
       250        260        270        280        290        300 
YRRCGFPQLW AASAFKGATG PSQAVPPVEH HLRNHVQWLQ VAGSGPTDSL QGIILTGWQR 
       310        320        330        340        350        360 
YDHYSVLCEL LPAGVPSLAA CLQLLLRGGF DEDVKAKVEN LLGISSLEKT DPVREGAGSF 
       370        380        390        400        410        420 
PGSNILALVT QVSLHLRSSV DALLEGNRYV TGWFSPYHRQ RKLIHPVMVQ HIQPAALSLL 
       430        440        450        460        470        480 
AQWSTLVQEL EAALQLAFYP DAVEEWLEEN VHPSLQRLQA LLQDLSEVSA PPLPPTSPGR 
   
DVAQDP

Isoforms

- Isoform 2 of Hexosaminidase D

Sequence View

        10         20         30         40         50         60 
MSGSTPFQMR LVHLDLKGAP PKVSYLSEIF PLFRALGANG LLIEYEDMFP YEGPLRLLRA 
        70         80         90        100        110        120 
KYAYSPSEIK EILHLAGLNE LEVIPLVQTF GHMEFVLKHT AFAHLREVGS FPCTLNPHEA 
       130        140        150        160        170        180 
ESLALVGAMI DQVLELHPGA QRLHIGCDEV YYLGEGEASR RWLQQEQNST GKLCLSHMRA 
       190        200        210        220        230        240 
VASGVKARRP SVTPLVWDDM LRDLPEDQLA ASGVPQLVEP VLWDYTADLD VHGKVLLMQK 
       250        260        270        280        290        300 
YRRCGFPQLW AASAFKGATG PSQAVPPVEH HLRNHVQWLQ VAGSGPTDSL QGIILTGWQR 
       310        320        330        340        350        360 
YDHYSVLCEL LPAGVPSLAA CLQLLLRGGF DEDVKAKVEN LLGISSLEKT DPVREGAGSF 
       370        380        390        400        410        420 
PGSNILALVT QVSLHLRSSV DALLEGNRYV TGWFSPYHRQ RKLIHPVMVQ HIQPAALSLL 
       430        440        450        460        470        480 
AQWSTLVQEL EAALQLAFYP DAVEEWLEEN VHPSLQRLQA LLQDLSEVSA PPLPPTSPGR 
   
DVAQDP



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Protease Assignment Confidence:


Evidence Names:


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Protein Neighborhood

Domains & Features

1 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    Q8WVB3-1-unknown MSGSTP... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    Q8WVB3-1-unknown MSGSTP... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt76938

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...VAQDP 486 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)