Q8WXI7: Mucin-16 {ECO:0000305}
Protein names | - Mucin-16 {ECO:0000305} - MUC-16 - Ovarian cancer-related tumor marker CA125 {ECO:0000303|PubMed:12218296} - CA-125 {ECO:0000303|PubMed:12218296} - Ovarian carcinoma antigen CA125 {ECO:0000303|PubMed:11369781} |
---|---|
Gene names | MUC16 |
Organism | Homo sapiens |
Protease Family | |
Protease ID | |
Chromosome location | |
UniProt ID | Q8WXI7 |
1
N-termini
1
C-termini
0
Cleavages
0
Substrates
Sequence
10 20 30 40 50 60
MLKPSGLPGS SSPTRSLMTG SRSTKATPEM DSGLTGATLS PKTSTGAIVV TEHTLPFTSP
70 80 90 100 110 120
DKTLASPTSS VVGRTTQSLG VMSSALPEST SRGMTHSEQR TSPSLSPQVN GTPSRNYPAT
130 140 150 160 170 180
SMVSGLSSPR TRTSSTEGNF TKEASTYTLT VETTSGPVTE KYTVPTETST TEGDSTETPW
190 200 210 220 230 240
DTRYIPVKIT SPMKTFADST ASKENAPVSM TPAETTVTDS HTPGRTNPSF GTLYSSFLDL
250 260 270 280 290 300
SPKGTPNSRG ETSLELILST TGYPFSSPEP GSAGHSRIST SAPLSSSASV LDNKISETSI
310 320 330 340 350 360
FSGQSLTSPL SPGVPEARAS TMPNSAIPFS MTLSNAETSA ERVRSTISSL GTPSISTKQT
370 380 390 400 410 420
AETILTFHAF AETMDIPSTH IAKTLASEWL GSPGTLGGTS TSALTTTSPS TTLVSEETNT
430 440 450 460 470 480
HHSTSGKETE GTLNTSMTPL ETSAPGEESE MTATLVPTLG FTTLDSKIRS PSQVSSSHPT
490 500 510 520 530 540
RELRTTGSTS GRQSSSTAAH GSSDILRATT SSTSKASSWT SESTAQQFSE PQHTQWVETS
550 560 570 580 590 600
PSMKTERPPA STSVAAPITT SVPSVVSGFT TLKTSSTKGI WLEETSADTL IGESTAGPTT
610 620 630 640 650 660
HQFAVPTGIS MTGGSSTRGS QGTTHLLTRA TASSETSADL TLATNGVPVS VSPAVSKTAA
670 680 690 700 710 720
GSSPPGGTKP SYTMVSSVIP ETSSLQSSAF REGTSLGLTP LNTRHPFSSP EPDSAGHTKI
730 740 750 760 770 780
STSIPLLSSA SVLEDKVSAT STFSHHKATS SITTGTPEIS TKTKPSSAVL SSMTLSNAAT
790 800 810 820 830 840
SPERVRNATS PLTHPSPSGE ETAGSVLTLS TSAETTDSPN IHPTGTLTSE SSESPSTLSL
850 860 870 880 890 900
PSVSGVKTTF SSSTPSTHLF TSGEETEETS NPSVSQPETS VSRVRTTLAS TSVPTPVFPT
910 920 930 940 950 960
MDTWPTRSAQ FSSSHLVSEL RATSSTSVTN STGSALPKIS HLTGTATMSQ TNRDTFNDSA
970 980 990 1000 1010 1020
APQSTTWPET SPRFKTGLPS ATTTVSTSAT SLSATVMVSK FTSPATSSME ATSIREPSTT
1030 1040 1050 1060 1070 1080
ILTTETTNGP GSMAVASTNI PIGKGYITEG RLDTSHLPIG TTASSETSMD FTMAKESVSM
1090 1100 1110 1120 1130 1140
SVSPSQSMDA AGSSTPGRTS QFVDTFSDDV YHLTSREITI PRDGTSSALT PQMTATHPPS
1150 1160 1170 1180 1190 1200
PDPGSARSTW LGILSSSPSS PTPKVTMSST FSTQRVTTSM IMDTVETSRW NMPNLPSTTS
1210 1220 1230 1240 1250 1260
LTPSNIPTSG AIGKSTLVPL DTPSPATSLE ASEGGLPTLS TYPESTNTPS IHLGAHASSE
1270 1280 1290 1300 1310 1320
SPSTIKLTMA SVVKPGSYTP LTFPSIETHI HVSTARMAYS SGSSPEMTAP GETNTGSTWD
1330 1340 1350 1360 1370 1380
PTTYITTTDP KDTSSAQVST PHSVRTLRTT ENHPKTESAT PAAYSGSPKI SSSPNLTSPA
1390 1400 1410 1420 1430 1440
TKAWTITDTT EHSTQLHYTK LAEKSSGFET QSAPGPVSVV IPTSPTIGSS TLELTSDVPG
1450 1460 1470 1480 1490 1500
EPLVLAPSEQ TTITLPMATW LSTSLTEEMA STDLDISSPS SPMSTFAIFP PMSTPSHELS
1510 1520 1530 1540 1550 1560
KSEADTSAIR NTDSTTLDQH LGIRSLGRTG DLTTVPITPL TTTWTSVIEH STQAQDTLSA
1570 1580 1590 1600 1610 1620
TMSPTHVTQS LKDQTSIPAS ASPSHLTEVY PELGTQGRSS SEATTFWKPS TDTLSREIET
1630 1640 1650 1660 1670 1680
GPTNIQSTPP MDNTTTGSSS SGVTLGIAHL PIGTSSPAET STNMALERRS STATVSMAGT
1690 1700 1710 1720 1730 1740
MGLLVTSAPG RSISQSLGRV SSVLSESTTE GVTDSSKGSS PRLNTQGNTA LSSSLEPSYA
1750 1760 1770 1780 1790 1800
EGSQMSTSIP LTSSPTTPDV EFIGGSTFWT KEVTTVMTSD ISKSSARTES SSATLMSTAL
1810 1820 1830 1840 1850 1860
GSTENTGKEK LRTASMDLPS PTPSMEVTPW ISLTLSNAPN TTDSLDLSHG VHTSSAGTLA
1870 1880 1890 1900 1910 1920
TDRSLNTGVT RASRLENGSD TSSKSLSMGN STHTSMTYTE KSEVSSSIHP RPETSAPGAE
1930 1940 1950 1960 1970 1980
TTLTSTPGNR AISLTLPFSS IPVEEVISTG ITSGPDINSA PMTHSPITPP TIVWTSTGTI
1990 2000 2010 2020 2030 2040
EQSTQPLHAV SSEKVSVQTQ STPYVNSVAV SASPTHENSV SSGSSTSSPY SSASLESLDS
2050 2060 2070 2080 2090 2100
TISRRNAITS WLWDLTTSLP TTTWPSTSLS EALSSGHSGV SNPSSTTTEF PLFSAASTSA
2110 2120 2130 2140 2150 2160
AKQRNPETET HGPQNTAAST LNTDASSVTG LSETPVGASI SSEVPLPMAI TSRSDVSGLT
2170 2180 2190 2200 2210 2220
SESTANPSLG TASSAGTKLT RTISLPTSES LVSFRMNKDP WTVSIPLGSH PTTNTETSIP
2230 2240 2250 2260 2270 2280
VNSAGPPGLS TVASDVIDTP SDGAESIPTV SFSPSPDTEV TTISHFPEKT THSFRTISSL
2290 2300 2310 2320 2330 2340
THELTSRVTP IPGDWMSSAM STKPTGASPS ITLGERRTIT SAAPTTSPIV LTASFTETST
2350 2360 2370 2380 2390 2400
VSLDNETTVK TSDILDARKT NELPSDSSSS SDLINTSIAS STMDVTKTAS ISPTSISGMT
2410 2420 2430 2440 2450 2460
ASSSPSLFSS DRPQVPTSTT ETNTATSPSV SSNTYSLDGG SNVGGTPSTL PPFTITHPVE
2470 2480 2490 2500 2510 2520
TSSALLAWSR PVRTFSTMVS TDTASGENPT SSNSVVTSVP APGTWTSVGS TTDLPAMGFL
2530 2540 2550 2560 2570 2580
KTSPAGEAHS LLASTIEPAT AFTPHLSAAV VTGSSATSEA SLLTTSESKA IHSSPQTPTT
2590 2600 2610 2620 2630 2640
PTSGANWETS ATPESLLVVT ETSDTTLTSK ILVTDTILFS TVSTPPSKFP STGTLSGASF
2650 2660 2670 2680 2690 2700
PTLLPDTPAI PLTATEPTSS LATSFDSTPL VTIASDSLGT VPETTLTMSE TSNGDALVLK
2710 2720 2730 2740 2750 2760
TVSNPDRSIP GITIQGVTES PLHPSSTSPS KIVAPRNTTY EGSITVALST LPAGTTGSLV
2770 2780 2790 2800 2810 2820
FSQSSENSET TALVDSSAGL ERASVMPLTT GSQGMASSGG IRSGSTHSTG TKTFSSLPLT
2830 2840 2850 2860 2870 2880
MNPGEVTAMS EITTNRLTAT QSTAPKGIPV KPTSAESGLL TPVSASSSPS KAFASLTTAP
2890 2900 2910 2920 2930 2940
PTWGIPQSTL TFEFSEVPSL DTKSASLPTP GQSLNTIPDS DASTASSSLS KSPEKNPRAR
2950 2960 2970 2980 2990 3000
MMTSTKAISA SSFQSTGFTE TPEGSASPSM AGHEPRVPTS GTGDPRYASE SMSYPDPSKA
3010 3020 3030 3040 3050 3060
SSAMTSTSLA SKLTTLFSTG QAARSGSSSS PISLSTEKET SFLSPTASTS RKTSLFLGPS
3070 3080 3090 3100 3110 3120
MARQPNILVH LQTSALTLSP TSTLNMSQEE PPELTSSQTI AEEEGTTAET QTLTFTPSET
3130 3140 3150 3160 3170 3180
PTSLLPVSSP TEPTARRKSS PETWASSISV PAKTSLVETT DGTLVTTIKM SSQAAQGNST
3190 3200 3210 3220 3230 3240
WPAPAEETGS SPAGTSPGSP EMSTTLKIMS SKEPSISPEI RSTVRNSPWK TPETTVPMET
3250 3260 3270 3280 3290 3300
TVEPVTLQST ALGSGSTSIS HLPTGTTSPT KSPTENMLAT ERVSLSPSPP EAWTNLYSGT
3310 3320 3330 3340 3350 3360
PGGTRQSLAT MSSVSLESPT ARSITGTGQQ SSPELVSKTT GMEFSMWHGS TGGTTGDTHV
3370 3380 3390 3400 3410 3420
SLSTSSNILE DPVTSPNSVS SLTDKSKHKT ETWVSTTAIP STVLNNKIMA AEQQTSRSVD
3430 3440 3450 3460 3470 3480
EAYSSTSSWS DQTSGSDITL GASPDVTNTL YITSTAQTTS LVSLPSGDQG ITSLTNPSGG
3490 3500 3510 3520 3530 3540
KTSSASSVTS PSIGLETLRA NVSAVKSDIA PTAGHLSQTS SPAEVSILDV TTAPTPGIST
3550 3560 3570 3580 3590 3600
TITTMGTNSI STTTPNPEVG MSTMDSTPAT ERRTTSTEHP STWSSTAASD SWTVTDMTSN
3610 3620 3630 3640 3650 3660
LKVARSPGTI STMHTTSFLA SSTELDSMST PHGRITVIGT SLVTPSSDAS AVKTETSTSE
3670 3680 3690 3700 3710 3720
RTLSPSDTTA STPISTFSRV QRMSISVPDI LSTSWTPSST EAEDVPVSMV STDHASTKTD
3730 3740 3750 3760 3770 3780
PNTPLSTFLF DSLSTLDWDT GRSLSSATAT TSAPQGATTP QELTLETMIS PATSQLPFSI
3790 3800 3810 3820 3830 3840
GHITSAVTPA AMARSSGVTF SRPDPTSKKA EQTSTQLPTT TSAHPGQVPR SAATTLDVIP
3850 3860 3870 3880 3890 3900
HTAKTPDATF QRQGQTALTT EARATSDSWN EKEKSTPSAP WITEMMNSVS EDTIKEVTSS
3910 3920 3930 3940 3950 3960
SSVLRTLNTL DINLESGTTS SPSWKSSPYE RIAPSESTTD KEAIHPSTNT VETTGWVTSS
3970 3980 3990 4000 4010 4020
EHASHSTIPA HSASSKLTSP VVTTSTREQA IVSMSTTTWP ESTRARTEPN SFLTIELRDV
4030 4040 4050 4060 4070 4080
SPYMDTSSTT QTSIISSPGS TAITKGPRTE ITSSKRISSS FLAQSMRSSD SPSEAITRLS
4090 4100 4110 4120 4130 4140
NFPAMTESGG MILAMQTSPP GATSLSAPTL DTSATASWTG TPLATTQRFT YSEKTTLFSK
4150 4160 4170 4180 4190 4200
GPEDTSQPSP PSVEETSSSS SLVPIHATTS PSNILLTSQG HSPSSTPPVT SVFLSETSGL
4210 4220 4230 4240 4250 4260
GKTTDMSRIS LEPGTSLPPN LSSTAGEALS TYEASRDTKA IHHSADTAVT NMEATSSEYS
4270 4280 4290 4300 4310 4320
PIPGHTKPSK ATSPLVTSHI MGDITSSTSV FGSSETTEIE TVSSVNQGLQ ERSTSQVASS
4330 4340 4350 4360 4370 4380
ATETSTVITH VSSGDATTHV TKTQATFSSG TSISSPHQFI TSTNTFTDVS TNPSTSLIMT
4390 4400 4410 4420 4430 4440
ESSGVTITTQ TGPTGAATQG PYLLDTSTMP YLTETPLAVT PDFMQSEKTT LISKGPKDVS
4450 4460 4470 4480 4490 4500
WTSPPSVAET SYPSSLTPFL VTTIPPATST LQGQHTSSPV SATSVLTSGL VKTTDMLNTS
4510 4520 4530 4540 4550 4560
MEPVTNSPQN LNNPSNEILA TLAATTDIET IHPSINKAVT NMGTASSAHV LHSTLPVSSE
4570 4580 4590 4600 4610 4620
PSTATSPMVP ASSMGDALAS ISIPGSETTD IEGEPTSSLT AGRKENSTLQ EMNSTTESNI
4630 4640 4650 4660 4670 4680
ILSNVSVGAI TEATKMEVPS FDATFIPTPA QSTKFPDIFS VASSRLSNSP PMTISTHMTT
4690 4700 4710 4720 4730 4740
TQTGSSGATS KIPLALDTST LETSAGTPSV VTEGFAHSKI TTAMNNDVKD VSQTNPPFQD
4750 4760 4770 4780 4790 4800
EASSPSSQAP VLVTTLPSSV AFTPQWHSTS SPVSMSSVLT SSLVKTAGKV DTSLETVTSS
4810 4820 4830 4840 4850 4860
PQSMSNTLDD ISVTSAATTD IETTHPSINT VVTNVGTTGS AFESHSTVSA YPEPSKVTSP
4870 4880 4890 4900 4910 4920
NVTTSTMEDT TISRSIPKSS KTTRTETETT SSLTPKLRET SISQEITSST ETSTVPYKEL
4930 4940 4950 4960 4970 4980
TGATTEVSRT DVTSSSSTSF PGPDQSTVSL DISTETNTRL STSPIMTESA EITITTQTGP
4990 5000 5010 5020 5030 5040
HGATSQDTFT MDPSNTTPQA GIHSAMTHGF SQLDVTTLMS RIPQDVSWTS PPSVDKTSSP
5050 5060 5070 5080 5090 5100
SSFLSSPAMT TPSLISSTLP EDKLSSPMTS LLTSGLVKIT DILRTRLEPV TSSLPNFSST
5110 5120 5130 5140 5150 5160
SDKILATSKD SKDTKEIFPS INTEETNVKA NNSGHESHSP ALADSETPKA TTQMVITTTV
5170 5180 5190 5200 5210 5220
GDPAPSTSMP VHGSSETTNI KREPTYFLTP RLRETSTSQE SSFPTDTSFL LSKVPTGTIT
5230 5240 5250 5260 5270 5280
EVSSTGVNSS SKISTPDHDK STVPPDTFTG EIPRVFTSSI KTKSAEMTIT TQASPPESAS
5290 5300 5310 5320 5330 5340
HSTLPLDTST TLSQGGTHST VTQGFPYSEV TTLMGMGPGN VSWMTTPPVE ETSSVSSLMS
5350 5360 5370 5380 5390 5400
SPAMTSPSPV SSTSPQSIPS SPLPVTALPT SVLVTTTDVL GTTSPESVTS SPPNLSSITH
5410 5420 5430 5440 5450 5460
ERPATYKDTA HTEAAMHHST NTAVTNVGTS GSGHKSQSSV LADSETSKAT PLMSTTSTLG
5470 5480 5490 5500 5510 5520
DTSVSTSTPN ISQTNQIQTE PTASLSPRLR ESSTSEKTSS TTETNTAFSY VPTGAITQAS
5530 5540 5550 5560 5570 5580
RTEISSSRTS ISDLDRPTIA PDISTGMITR LFTSPIMTKS AEMTVTTQTT TPGATSQGIL
5590 5600 5610 5620 5630 5640
PWDTSTTLFQ GGTHSTVSQG FPHSEITTLR SRTPGDVSWM TTPPVEETSS GFSLMSPSMT
5650 5660 5670 5680 5690 5700
SPSPVSSTSP ESIPSSPLPV TALLTSVLVT TTNVLGTTSP EPVTSSPPNL SSPTQERLTT
5710 5720 5730 5740 5750 5760
YKDTAHTEAM HASMHTNTAV ANVGTSISGH ESQSSVPADS HTSKATSPMG ITFAMGDTSV
5770 5780 5790 5800 5810 5820
STSTPAFFET RIQTESTSSL IPGLRDTRTS EEINTVTETS TVLSEVPTTT TTEVSRTEVI
5830 5840 5850 5860 5870 5880
TSSRTTISGP DHSKMSPYIS TETITRLSTF PFVTGSTEMA ITNQTGPIGT ISQATLTLDT
5890 5900 5910 5920 5930 5940
SSTASWEGTH SPVTQRFPHS EETTTMSRST KGVSWQSPPS VEETSSPSSP VPLPAITSHS
5950 5960 5970 5980 5990 6000
SLYSAVSGSS PTSALPVTSL LTSGRRKTID MLDTHSELVT SSLPSASSFS GEILTSEAST
6010 6020 6030 6040 6050 6060
NTETIHFSEN TAETNMGTTN SMHKLHSSVS IHSQPSGHTP PKVTGSMMED AIVSTSTPGS
6070 6080 6090 6100 6110 6120
PETKNVDRDS TSPLTPELKE DSTALVMNST TESNTVFSSV SLDAATEVSR AEVTYYDPTF
6130 6140 6150 6160 6170 6180
MPASAQSTKS PDISPEASSS HSNSPPLTIS THKTIATQTG PSGVTSLGQL TLDTSTIATS
6190 6200 6210 6220 6230 6240
AGTPSARTQD FVDSETTSVM NNDLNDVLKT SPFSAEEANS LSSQAPLLVT TSPSPVTSTL
6250 6260 6270 6280 6290 6300
QEHSTSSLVS VTSVPTPTLA KITDMDTNLE PVTRSPQNLR NTLATSEATT DTHTMHPSIN
6310 6320 6330 6340 6350 6360
TAVANVGTTS SPNEFYFTVS PDSDPYKATS AVVITSTSGD SIVSTSMPRS SAMKKIESET
6370 6380 6390 6400 6410 6420
TFSLIFRLRE TSTSQKIGSS SDTSTVFDKA FTAATTEVSR TELTSSSRTS IQGTEKPTMS
6430 6440 6450 6460 6470 6480
PDTSTRSVTM LSTFAGLTKS EERTIATQTG PHRATSQGTL TWDTSITTSQ AGTHSAMTHG
6490 6500 6510 6520 6530 6540
FSQLDLSTLT SRVPEYISGT SPPSVEKTSS SSSLLSLPAI TSPSPVPTTL PESRPSSPVH
6550 6560 6570 6580 6590 6600
LTSLPTSGLV KTTDMLASVA SLPPNLGSTS HKIPTTSEDI KDTEKMYPST NIAVTNVGTT
6610 6620 6630 6640 6650 6660
TSEKESYSSV PAYSEPPKVT SPMVTSFNIR DTIVSTSMPG SSEITRIEME STFSLAHGLK
6670 6680 6690 6700 6710 6720
GTSTSQDPIV STEKSAVLHK LTTGATETSR TEVASSRRTS IPGPDHSTES PDISTEVIPS
6730 6740 6750 6760 6770 6780
LPISLGITES SNMTIITRTG PPLGSTSQGT FTLDTPTTSS RAGTHSMATQ EFPHSEMTTV
6790 6800 6810 6820 6830 6840
MNKDPEILSW TIPPSIEKTS FSSSLMPSPA MTSPPVSSTL PKTIHTTPSP MTSLLTPSLV
6850 6860 6870 6880 6890 6900
MTTDTLGTSP EPTTSSPPNL SSTSHEILTT DEDTTAIEAM HPSTSTAATN VETTSSGHGS
6910 6920 6930 6940 6950 6960
QSSVLADSEK TKATAPMDTT STMGHTTVST SMSVSSETTK IKRESTYSLT PGLRETSISQ
6970 6980 6990 7000 7010 7020
NASFSTDTSI VLSEVPTGTT AEVSRTEVTS SGRTSIPGPS QSTVLPEIST RTMTRLFASP
7030 7040 7050 7060 7070 7080
TMTESAEMTI PTQTGPSGST SQDTLTLDTS TTKSQAKTHS TLTQRFPHSE MTTLMSRGPG
7090 7100 7110 7120 7130 7140
DMSWQSSPSL ENPSSLPSLL SLPATTSPPP ISSTLPVTIS SSPLPVTSLL TSSPVTTTDM
7150 7160 7170 7180 7190 7200
LHTSPELVTS SPPKLSHTSD ERLTTGKDTT NTEAVHPSTN TAASNVEIPS SGHESPSSAL
7210 7220 7230 7240 7250 7260
ADSETSKATS PMFITSTQED TTVAISTPHF LETSRIQKES ISSLSPKLRE TGSSVETSSA
7270 7280 7290 7300 7310 7320
IETSAVLSEV SIGATTEISR TEVTSSSRTS ISGSAESTML PEISTTRKII KFPTSPILAE
7330 7340 7350 7360 7370 7380
SSEMTIKTQT SPPGSTSEST FTLDTSTTPS LVITHSTMTQ RLPHSEITTL VSRGAGDVPR
7390 7400 7410 7420 7430 7440
PSSLPVEETS PPSSQLSLSA MISPSPVSST LPASSHSSSA SVTSLLTPGQ VKTTEVLDAS
7450 7460 7470 7480 7490 7500
AEPETSSPPS LSSTSVEILA TSEVTTDTEK IHPFSNTAVT KVGTSSSGHE SPSSVLPDSE
7510 7520 7530 7540 7550 7560
TTKATSAMGT ISIMGDTSVS TLTPALSNTR KIQSEPASSL TTRLRETSTS EETSLATEAN
7570 7580 7590 7600 7610 7620
TVLSKVSTGA TTEVSRTEAI SFSRTSMSGP EQSTMSQDIS IGTIPRISAS SVLTESAKMT
7630 7640 7650 7660 7670 7680
ITTQTGPSES TLESTLNLNT ATTPSWVETH SIVIQGFPHP EMTTSMGRGP GGVSWPSPPF
7690 7700 7710 7720 7730 7740
VKETSPPSSP LSLPAVTSPH PVSTTFLAHI PPSPLPVTSL LTSGPATTTD ILGTSTEPGT
7750 7760 7770 7780 7790 7800
SSSSSLSTTS HERLTTYKDT AHTEAVHPST NTGGTNVATT SSGYKSQSSV LADSSPMCTT
7810 7820 7830 7840 7850 7860
STMGDTSVLT STPAFLETRR IQTELASSLT PGLRESSGSE GTSSGTKMST VLSKVPTGAT
7870 7880 7890 7900 7910 7920
TEISKEDVTS IPGPAQSTIS PDISTRTVSW FSTSPVMTES AEITMNTHTS PLGATTQGTS
7930 7940 7950 7960 7970 7980
TLDTSSTTSL TMTHSTISQG FSHSQMSTLM RRGPEDVSWM SPPLLEKTRP SFSLMSSPAT
7990 8000 8010 8020 8030 8040
TSPSPVSSTL PESISSSPLP VTSLLTSGLA KTTDMLHKSS EPVTNSPANL SSTSVEILAT
8050 8060 8070 8080 8090 8100
SEVTTDTEKT HPSSNRTVTD VGTSSSGHES TSFVLADSQT SKVTSPMVIT STMEDTSVST
8110 8120 8130 8140 8150 8160
STPGFFETSR IQTEPTSSLT LGLRKTSSSE GTSLATEMST VLSGVPTGAT AEVSRTEVTS
8170 8180 8190 8200 8210 8220
SSRTSISGFA QLTVSPETST ETITRLPTSS IMTESAEMMI KTQTDPPGST PESTHTVDIS
8230 8240 8250 8260 8270 8280
TTPNWVETHS TVTQRFSHSE MTTLVSRSPG DMLWPSQSSV EETSSASSLL SLPATTSPSP
8290 8300 8310 8320 8330 8340
VSSTLVEDFP SASLPVTSLL NPGLVITTDR MGISREPGTS STSNLSSTSH ERLTTLEDTV
8350 8360 8370 8380 8390 8400
DTEDMQPSTH TAVTNVRTSI SGHESQSSVL SDSETPKATS PMGTTYTMGE TSVSISTSDF
8410 8420 8430 8440 8450 8460
FETSRIQIEP TSSLTSGLRE TSSSERISSA TEGSTVLSEV PSGATTEVSR TEVISSRGTS
8470 8480 8490 8500 8510 8520
MSGPDQFTIS PDISTEAITR LSTSPIMTES AESAITIETG SPGATSEGTL TLDTSTTTFW
8530 8540 8550 8560 8570 8580
SGTHSTASPG FSHSEMTTLM SRTPGDVPWP SLPSVEEASS VSSSLSSPAM TSTSFFSTLP
8590 8600 8610 8620 8630 8640
ESISSSPHPV TALLTLGPVK TTDMLRTSSE PETSSPPNLS STSAEILATS EVTKDREKIH
8650 8660 8670 8680 8690 8700
PSSNTPVVNV GTVIYKHLSP SSVLADLVTT KPTSPMATTS TLGNTSVSTS TPAFPETMMT
8710 8720 8730 8740 8750 8760
QPTSSLTSGL REISTSQETS SATERSASLS GMPTGATTKV SRTEALSLGR TSTPGPAQST
8770 8780 8790 8800 8810 8820
ISPEISTETI TRISTPLTTT GSAEMTITPK TGHSGASSQG TFTLDTSSRA SWPGTHSAAT
8830 8840 8850 8860 8870 8880
HRSPHSGMTT PMSRGPEDVS WPSRPSVEKT SPPSSLVSLS AVTSPSPLYS TPSESSHSSP
8890 8900 8910 8920 8930 8940
LRVTSLFTPV MMKTTDMLDT SLEPVTTSPP SMNITSDESL ATSKATMETE AIQLSENTAV
8950 8960 8970 8980 8990 9000
TQMGTISARQ EFYSSYPGLP EPSKVTSPVV TSSTIKDIVS TTIPASSEIT RIEMESTSTL
9010 9020 9030 9040 9050 9060
TPTPRETSTS QEIHSATKPS TVPYKALTSA TIEDSMTQVM SSSRGPSPDQ STMSQDISTE
9070 9080 9090 9100 9110 9120
VITRLSTSPI KTESTEMTIT TQTGSPGATS RGTLTLDTST TFMSGTHSTA SQGFSHSQMT
9130 9140 9150 9160 9170 9180
ALMSRTPGDV PWLSHPSVEE ASSASFSLSS PVMTSSSPVS STLPDSIHSS SLPVTSLLTS
9190 9200 9210 9220 9230 9240
GLVKTTELLG TSSEPETSSP PNLSSTSAEI LAITEVTTDT EKLEMTNVVT SGYTHESPSS
9250 9260 9270 9280 9290 9300
VLADSVTTKA TSSMGITYPT GDTNVLTSTP AFSDTSRIQT KSKLSLTPGL METSISEETS
9310 9320 9330 9340 9350 9360
SATEKSTVLS SVPTGATTEV SRTEAISSSR TSIPGPAQST MSSDTSMETI TRISTPLTRK
9370 9380 9390 9400 9410 9420
ESTDMAITPK TGPSGATSQG TFTLDSSSTA SWPGTHSATT QRFPQSVVTT PMSRGPEDVS
9430 9440 9450 9460 9470 9480
WPSPLSVEKN SPPSSLVSSS SVTSPSPLYS TPSGSSHSSP VPVTSLFTSI MMKATDMLDA
9490 9500 9510 9520 9530 9540
SLEPETTSAP NMNITSDESL AASKATTETE AIHVFENTAA SHVETTSATE ELYSSSPGFS
9550 9560 9570 9580 9590 9600
EPTKVISPVV TSSSIRDNMV STTMPGSSGI TRIEIESMSS LTPGLRETRT SQDITSSTET
9610 9620 9630 9640 9650 9660
STVLYKMPSG ATPEVSRTEV MPSSRTSIPG PAQSTMSLDI SDEVVTRLST SPIMTESAEI
9670 9680 9690 9700 9710 9720
TITTQTGYSL ATSQVTLPLG TSMTFLSGTH STMSQGLSHS EMTNLMSRGP ESLSWTSPRF
9730 9740 9750 9760 9770 9780
VETTRSSSSL TSLPLTTSLS PVSSTLLDSS PSSPLPVTSL ILPGLVKTTE VLDTSSEPKT
9790 9800 9810 9820 9830 9840
SSSPNLSSTS VEIPATSEIM TDTEKIHPSS NTAVAKVRTS SSVHESHSSV LADSETTITI
9850 9860 9870 9880 9890 9900
PSMGITSAVD DTTVFTSNPA FSETRRIPTE PTFSLTPGFR ETSTSEETTS ITETSAVLYG
9910 9920 9930 9940 9950 9960
VPTSATTEVS MTEIMSSNRI HIPDSDQSTM SPDIITEVIT RLSSSSMMSE STQMTITTQK
9970 9980 9990 10000 10010 10020
SSPGATAQST LTLATTTAPL ARTHSTVPPR FLHSEMTTLM SRSPENPSWK SSLFVEKTSS
10030 10040 10050 10060 10070 10080
SSSLLSLPVT TSPSVSSTLP QSIPSSSFSV TSLLTPGMVK TTDTSTEPGT SLSPNLSGTS
10090 10100 10110 10120 10130 10140
VEILAASEVT TDTEKIHPSS SMAVTNVGTT SSGHELYSSV SIHSEPSKAT YPVGTPSSMA
10150 10160 10170 10180 10190 10200
ETSISTSMPA NFETTGFEAE PFSHLTSGFR KTNMSLDTSS VTPTNTPSSP GSTHLLQSSK
10210 10220 10230 10240 10250 10260
TDFTSSAKTS SPDWPPASQY TEIPVDIITP FNASPSITES TGITSFPESR FTMSVTESTH
10270 10280 10290 10300 10310 10320
HLSTDLLPSA ETISTGTVMP SLSEAMTSFA TTGVPRAISG SGSPFSRTES GPGDATLSTI
10330 10340 10350 10360 10370 10380
AESLPSSTPV PFSSSTFTTT DSSTIPALHE ITSSSATPYR VDTSLGTESS TTEGRLVMVS
10390 10400 10410 10420 10430 10440
TLDTSSQPGR TSSSPILDTR MTESVELGTV TSAYQVPSLS TRLTRTDGIM EHITKIPNEA
10450 10460 10470 10480 10490 10500
AHRGTIRPVK GPQTSTSPAS PKGLHTGGTK RMETTTTALK TTTTALKTTS RATLTTSVYT
10510 10520 10530 10540 10550 10560
PTLGTLTPLN ASMQMASTIP TEMMITTPYV FPDVPETTSS LATSLGAETS TALPRTTPSV
10570 10580 10590 10600 10610 10620
FNRESETTAS LVSRSGAERS PVIQTLDVSS SEPDTTASWV IHPAETIPTV SKTTPNFFHS
10630 10640 10650 10660 10670 10680
ELDTVSSTAT SHGADVSSAI PTNISPSELD ALTPLVTISG TDTSTTFPTL TKSPHETETR
10690 10700 10710 10720 10730 10740
TTWLTHPAET SSTIPRTIPN FSHHESDATP SIATSPGAET SSAIPIMTVS PGAEDLVTSQ
10750 10760 10770 10780 10790 10800
VTSSGTDRNM TIPTLTLSPG EPKTIASLVT HPEAQTSSAI PTSTISPAVS RLVTSMVTSL
10810 10820 10830 10840 10850 10860
AAKTSTTNRA LTNSPGEPAT TVSLVTHPAQ TSPTVPWTTS IFFHSKSDTT PSMTTSHGAE
10870 10880 10890 10900 10910 10920
SSSAVPTPTV STEVPGVVTP LVTSSRAVIS TTIPILTLSP GEPETTPSMA TSHGEEASSA
10930 10940 10950 10960 10970 10980
IPTPTVSPGV PGVVTSLVTS SRAVTSTTIP ILTFSLGEPE TTPSMATSHG TEAGSAVPTV
10990 11000 11010 11020 11030 11040
LPEVPGMVTS LVASSRAVTS TTLPTLTLSP GEPETTPSMA TSHGAEASST VPTVSPEVPG
11050 11060 11070 11080 11090 11100
VVTSLVTSSS GVNSTSIPTL ILSPGELETT PSMATSHGAE ASSAVPTPTV SPGVSGVVTP
11110 11120 11130 11140 11150 11160
LVTSSRAVTS TTIPILTLSS SEPETTPSMA TSHGVEASSA VLTVSPEVPG MVTSLVTSSR
11170 11180 11190 11200 11210 11220
AVTSTTIPTL TISSDEPETT TSLVTHSEAK MISAIPTLAV SPTVQGLVTS LVTSSGSETS
11230 11240 11250 11260 11270 11280
AFSNLTVASS QPETIDSWVA HPGTEASSVV PTLTVSTGEP FTNISLVTHP AESSSTLPRT
11290 11300 11310 11320 11330 11340
TSRFSHSELD TMPSTVTSPE AESSSAISTT ISPGIPGVLT SLVTSSGRDI SATFPTVPES
11350 11360 11370 11380 11390 11400
PHESEATASW VTHPAVTSTT VPRTTPNYSH SEPDTTPSIA TSPGAEATSD FPTITVSPDV
11410 11420 11430 11440 11450 11460
PDMVTSQVTS SGTDTSITIP TLTLSSGEPE TTTSFITYSE THTSSAIPTL PVSPGASKML
11470 11480 11490 11500 11510 11520
TSLVISSGTD STTTFPTLTE TPYEPETTAI QLIHPAETNT MVPRTTPKFS HSKSDTTLPV
11530 11540 11550 11560 11570 11580
AITSPGPEAS SAVSTTTISP DMSDLVTSLV PSSGTDTSTT FPTLSETPYE PETTATWLTH
11590 11600 11610 11620 11630 11640
PAETSTTVSG TIPNFSHRGS DTAPSMVTSP GVDTRSGVPT TTIPPSIPGV VTSQVTSSAT
11650 11660 11670 11680 11690 11700
DTSTAIPTLT PSPGEPETTA SSATHPGTQT GFTVPIRTVP SSEPDTMASW VTHPPQTSTP
11710 11720 11730 11740 11750 11760
VSRTTSSFSH SSPDATPVMA TSPRTEASSA VLTTISPGAP EMVTSQITSS GAATSTTVPT
11770 11780 11790 11800 11810 11820
LTHSPGMPET TALLSTHPRT ETSKTFPAST VFPQVSETTA SLTIRPGAET STALPTQTTS
11830 11840 11850 11860 11870 11880
SLFTLLVTGT SRVDLSPTAS PGVSAKTAPL STHPGTETST MIPTSTLSLG LLETTGLLAT
11890 11900 11910 11920 11930 11940
SSSAETSTST LTLTVSPAVS GLSSASITTD KPQTVTSWNT ETSPSVTSVG PPEFSRTVTG
11950 11960 11970 11980 11990 12000
TTMTLIPSEM PTPPKTSHGE GVSPTTILRT TMVEATNLAT TGSSPTVAKT TTTFNTLAGS
12010 12020 12030 12040 12050 12060
LFTPLTTPGM STLASESVTS RTSYNHRSWI STTSSYNRRY WTPATSTPVT STFSPGISTS
12070 12080 12090 12100 12110 12120
SIPSSTAATV PFMVPFTLNF TITNLQYEED MRHPGSRKFN ATERELQGLL KPLFRNSSLE
12130 12140 12150 12160 12170 12180
YLYSGCRLAS LRPEKDSSAT AVDAICTHRP DPEDLGLDRE RLYWELSNLT NGIQELGPYT
12190 12200 12210 12220 12230 12240
LDRNSLYVNG FTHRSSMPTT STPGTSTVDV GTSGTPSSSP SPTTAGPLLM PFTLNFTITN
12250 12260 12270 12280 12290 12300
LQYEEDMRRT GSRKFNTMES VLQGLLKPLF KNTSVGPLYS GCRLTLLRPE KDGAATGVDA
12310 12320 12330 12340 12350 12360
ICTHRLDPKS PGLNREQLYW ELSKLTNDIE ELGPYTLDRN SLYVNGFTHQ SSVSTTSTPG
12370 12380 12390 12400 12410 12420
TSTVDLRTSG TPSSLSSPTI MAAGPLLVPF TLNFTITNLQ YGEDMGHPGS RKFNTTERVL
12430 12440 12450 12460 12470 12480
QGLLGPIFKN TSVGPLYSGC RLTSLRSEKD GAATGVDAIC IHHLDPKSPG LNRERLYWEL
12490 12500 12510 12520 12530 12540
SQLTNGIKEL GPYTLDRNSL YVNGFTHRTS VPTSSTPGTS TVDLGTSGTP FSLPSPATAG
12550 12560 12570 12580 12590 12600
PLLVLFTLNF TITNLKYEED MHRPGSRKFN TTERVLQTLL GPMFKNTSVG LLYSGCRLTL
12610 12620 12630 12640 12650 12660
LRSEKDGAAT GVDAICTHRL DPKSPGVDRE QLYWELSQLT NGIKELGPYT LDRNSLYVNG
12670 12680 12690 12700 12710 12720
FTHWIPVPTS STPGTSTVDL GSGTPSSLPS PTTAGPLLVP FTLNFTITNL KYEEDMHCPG
12730 12740 12750 12760 12770 12780
SRKFNTTERV LQSLLGPMFK NTSVGPLYSG CRLTLLRSEK DGAATGVDAI CTHRLDPKSP
12790 12800 12810 12820 12830 12840
GVDREQLYWE LSQLTNGIKE LGPYTLDRNS LYVNGFTHQT SAPNTSTPGT STVDLGTSGT
12850 12860 12870 12880 12890 12900
PSSLPSPTSA GPLLVPFTLN FTITNLQYEE DMHHPGSRKF NTTERVLQGL LGPMFKNTSV
12910 12920 12930 12940 12950 12960
GLLYSGCRLT LLRPEKNGAA TGMDAICSHR LDPKSPGLNR EQLYWELSQL THGIKELGPY
12970 12980 12990 13000 13010 13020
TLDRNSLYVN GFTHRSSVAP TSTPGTSTVD LGTSGTPSSL PSPTTAVPLL VPFTLNFTIT
13030 13040 13050 13060 13070 13080
NLQYGEDMRH PGSRKFNTTE RVLQGLLGPL FKNSSVGPLY SGCRLISLRS EKDGAATGVD
13090 13100 13110 13120 13130 13140
AICTHHLNPQ SPGLDREQLY WQLSQMTNGI KELGPYTLDR NSLYVNGFTH RSSGLTTSTP
13150 13160 13170 13180 13190 13200
WTSTVDLGTS GTPSPVPSPT TTGPLLVPFT LNFTITNLQY EENMGHPGSR KFNITESVLQ
13210 13220 13230 13240 13250 13260
GLLKPLFKST SVGPLYSGCR LTLLRPEKDG VATRVDAICT HRPDPKIPGL DRQQLYWELS
13270 13280 13290 13300 13310 13320
QLTHSITELG PYTLDRDSLY VNGFTQRSSV PTTSTPGTFT VQPETSETPS SLPGPTATGP
13330 13340 13350 13360 13370 13380
VLLPFTLNFT ITNLQYEEDM RRPGSRKFNT TERVLQGLLM PLFKNTSVSS LYSGCRLTLL
13390 13400 13410 13420 13430 13440
RPEKDGAATR VDAVCTHRPD PKSPGLDRER LYWKLSQLTH GITELGPYTL DRHSLYVNGF
13450 13460 13470 13480 13490 13500
THQSSMTTTR TPDTSTMHLA TSRTPASLSG PMTASPLLVL FTINFTITNL RYEENMHHPG
13510 13520 13530 13540 13550 13560
SRKFNTTERV LQGLLRPVFK NTSVGPLYSG CRLTLLRPKK DGAATKVDAI CTYRPDPKSP
13570 13580 13590 13600 13610 13620
GLDREQLYWE LSQLTHSITE LGPYTLDRDS LYVNGFTQRS SVPTTSIPGT PTVDLGTSGT
13630 13640 13650 13660 13670 13680
PVSKPGPSAA SPLLVLFTLN FTITNLRYEE NMQHPGSRKF NTTERVLQGL LRSLFKSTSV
13690 13700 13710 13720 13730 13740
GPLYSGCRLT LLRPEKDGTA TGVDAICTHH PDPKSPRLDR EQLYWELSQL THNITELGPY
13750 13760 13770 13780 13790 13800
ALDNDSLFVN GFTHRSSVST TSTPGTPTVY LGASKTPASI FGPSAASHLL ILFTLNFTIT
13810 13820 13830 13840 13850 13860
NLRYEENMWP GSRKFNTTER VLQGLLRPLF KNTSVGPLYS GCRLTLLRPE KDGEATGVDA
13870 13880 13890 13900 13910 13920
ICTHRPDPTG PGLDREQLYL ELSQLTHSIT ELGPYTLDRD SLYVNGFTHR SSVPTTSTGV
13930 13940 13950 13960 13970 13980
VSEEPFTLNF TINNLRYMAD MGQPGSLKFN ITDNVMQHLL SPLFQRSSLG ARYTGCRVIA
13990 14000 14010 14020 14030 14040
LRSVKNGAET RVDLLCTYLQ PLSGPGLPIK QVFHELSQQT HGITRLGPYS LDKDSLYLNG
14050 14060 14070 14080 14090 14100
YNEPGPDEPP TTPKPATTFL PPLSEATTAM GYHLKTLTLN FTISNLQYSP DMGKGSATFN
14110 14120 14130 14140 14150 14160
STEGVLQHLL RPLFQKSSMG PFYLGCQLIS LRPEKDGAAT GVDTTCTYHP DPVGPGLDIQ
14170 14180 14190 14200 14210 14220
QLYWELSQLT HGVTQLGFYV LDRDSLFING YAPQNLSIRG EYQINFHIVN WNLSNPDPTS
14230 14240 14250 14260 14270 14280
SEYITLLRDI QDKVTTLYKG SQLHDTFRFC LVTNLTMDSV LVTVKALFSS NLDPSLVEQV
14290 14300 14310 14320 14330 14340
FLDKTLNASF HWLGSTYQLV DIHVTEMESS VYQPTSSSST QHFYLNFTIT NLPYSQDKAQ
14350 14360 14370 14380 14390 14400
PGTTNYQRNK RNIEDALNQL FRNSSIKSYF SDCQVSTFRS VPNRHHTGVD SLCNFSPLAR
14410 14420 14430 14440 14450 14460
RVDRVAIYEE FLRMTRNGTQ LQNFTLDRSS VLVDGYSPNR NEPLTGNSDL PFWAVILIGL
14470 14480 14490 14500
AGLLGVITCL ICGVLVTTRR RKKEGEYNVQ QQCPGYYQSH LDLEDLQ
Isoforms
Sequence View
Protein Neighborhood
Domains & Features
1 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates
N-termini
Name | Sequence | Position | Modification | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMID) |
---|---|---|---|---|---|---|---|---|---|
Q8WXI7-1-unknown | MLKPSG... | 1 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot |
C-termini
Name | Sequence | Position | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
---|---|---|---|---|---|---|---|---|
... | 22152 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot |
Cleavages
Protease | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
---|
Substrates
Substrate | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
---|