TopFIND 4.0

Q8WXU2: Dynein assembly factor 4, axonemal {ECO:0000312|HGNC:HGNC:21493}

General Information

Protein names
- Dynein assembly factor 4, axonemal {ECO:0000312|HGNC:HGNC:21493}
- Dyslexia susceptibility 1 candidate gene 1 protein
Gene names DYX1C1
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID Q8WXU2

1

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MPLQVSDYSW QQTKTAVFLS LPLKGVCVRD TDVFCTENYL KVNFPPFLFE AFLYAPIDDE 
        70         80         90        100        110        120 
SSKAKIGNDT IVFTLYKKEA AMWETLSVTG VDKEMMQRIR EKSILQAQER AKEATEAKAA 
       130        140        150        160        170        180 
AKREDQKYAL SVMMKIEEEE RKKIEDMKEN ERIKATKALE AWKEYQRKAE EQKKIQREEK 
       190        200        210        220        230        240 
LCQKEKQIKE ERKKIKYKSL TRNLASRNLA PKGRNSENIF TEKLKEDSIP APRSVGSIKI 
       250        260        270        280        290        300 
NFTPRVFPTA LRESQVAEEE EWLHKQAEAR RAMNTDIAEL CDLKEEEKNP EWLKDKGNKL 
       310        320        330        340        350        360 
FATENYLAAI NAYNLAIRLN NKMPLLYLNR AACHLKLKNL HKAIEDSSKA LELLMPPVTD 
       370        380        390        400        410        420 
NANARMKAHV RRGTAFCQLE LYVEGLQDYE AALKIDPSNK IVQIDAEKIR NVIQGTELKS 
   

Isoforms

- Isoform 2 of Dyslexia susceptibility 1 candidate gene 1 protein - Isoform 3 of Dyslexia susceptibility 1 candidate gene 1 protein - Isoform 2 of Dynein assembly factor 4, axonemal - Isoform 3 of Dynein assembly factor 4, axonemal

Sequence View

        10         20         30         40         50         60 
MPLQVSDYSW QQTKTAVFLS LPLKGVCVRD TDVFCTENYL KVNFPPFLFE AFLYAPIDDE 
        70         80         90        100        110        120 
SSKAKIGNDT IVFTLYKKEA AMWETLSVTG VDKEMMQRIR EKSILQAQER AKEATEAKAA 
       130        140        150        160        170        180 
AKREDQKYAL SVMMKIEEEE RKKIEDMKEN ERIKATKALE AWKEYQRKAE EQKKIQREEK 
       190        200        210        220        230        240 
LCQKEKQIKE ERKKIKYKSL TRNLASRNLA PKGRNSENIF TEKLKEDSIP APRSVGSIKI 
       250        260        270        280        290        300 
NFTPRVFPTA LRESQVAEEE EWLHKQAEAR RAMNTDIAEL CDLKEEEKNP EWLKDKGNKL 
       310        320        330        340        350        360 
FATENYLAAI NAYNLAIRLN NKMPLLYLNR AACHLKLKNL HKAIEDSSKA LELLMPPVTD 
       370        380        390        400        410        420 
NANARMKAHV RRGTAFCQLE LYVEGLQDYE AALKIDPSNK IVQIDAEKIR NVIQGTELKS 
   
        10         20         30         40         50         60 
MPLQVSDYSW QQTKTAVFLS LPLKGVCVRD TDVFCTENYL KVNFPPFLFE AFLYAPIDDE 
        70         80         90        100        110        120 
SSKAKIGNDT IVFTLYKKEA AMWETLSVTG VDKEMMQRIR EKSILQAQER AKEATEAKAA 
       130        140        150        160        170        180 
AKREDQKYAL SVMMKIEEEE RKKIEDMKEN ERIKATKALE AWKEYQRKAE EQKKIQREEK 
       190        200        210        220        230        240 
LCQKEKQIKE ERKKIKYKSL TRNLASRNLA PKGRNSENIF TEKLKEDSIP APRSVGSIKI 
       250        260        270        280        290        300 
NFTPRVFPTA LRESQVAEEE EWLHKQAEAR RAMNTDIAEL CDLKEEEKNP EWLKDKGNKL 
       310        320        330        340        350        360 
FATENYLAAI NAYNLAIRLN NKMPLLYLNR AACHLKLKNL HKAIEDSSKA LELLMPPVTD 
       370        380        390        400        410        420 
NANARMKAHV RRGTAFCQLE LYVEGLQDYE AALKIDPSNK IVQIDAEKIR NVIQGTELKS 
   
        10         20         30         40         50         60 
MPLQVSDYSW QQTKTAVFLS LPLKGVCVRD TDVFCTENYL KVNFPPFLFE AFLYAPIDDE 
        70         80         90        100        110        120 
SSKAKIGNDT IVFTLYKKEA AMWETLSVTG VDKEMMQRIR EKSILQAQER AKEATEAKAA 
       130        140        150        160        170        180 
AKREDQKYAL SVMMKIEEEE RKKIEDMKEN ERIKATKALE AWKEYQRKAE EQKKIQREEK 
       190        200        210        220        230        240 
LCQKEKQIKE ERKKIKYKSL TRNLASRNLA PKGRNSENIF TEKLKEDSIP APRSVGSIKI 
       250        260        270        280        290        300 
NFTPRVFPTA LRESQVAEEE EWLHKQAEAR RAMNTDIAEL CDLKEEEKNP EWLKDKGNKL 
       310        320        330        340        350        360 
FATENYLAAI NAYNLAIRLN NKMPLLYLNR AACHLKLKNL HKAIEDSSKA LELLMPPVTD 
       370        380        390        400        410        420 
NANARMKAHV RRGTAFCQLE LYVEGLQDYE AALKIDPSNK IVQIDAEKIR NVIQGTELKS 
   
        10         20         30         40         50         60 
MPLQVSDYSW QQTKTAVFLS LPLKGVCVRD TDVFCTENYL KVNFPPFLFE AFLYAPIDDE 
        70         80         90        100        110        120 
SSKAKIGNDT IVFTLYKKEA AMWETLSVTG VDKEMMQRIR EKSILQAQER AKEATEAKAA 
       130        140        150        160        170        180 
AKREDQKYAL SVMMKIEEEE RKKIEDMKEN ERIKATKALE AWKEYQRKAE EQKKIQREEK 
       190        200        210        220        230        240 
LCQKEKQIKE ERKKIKYKSL TRNLASRNLA PKGRNSENIF TEKLKEDSIP APRSVGSIKI 
       250        260        270        280        290        300 
NFTPRVFPTA LRESQVAEEE EWLHKQAEAR RAMNTDIAEL CDLKEEEKNP EWLKDKGNKL 
       310        320        330        340        350        360 
FATENYLAAI NAYNLAIRLN NKMPLLYLNR AACHLKLKNL HKAIEDSSKA LELLMPPVTD 
       370        380        390        400        410        420 
NANARMKAHV RRGTAFCQLE LYVEGLQDYE AALKIDPSNK IVQIDAEKIR NVIQGTELKS 
   



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Protein Neighborhood

Domains & Features

1 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    Q8WXU2-1-unknown MPLQVS... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    Q8WXU2-1-unknown MPLQVS... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt73480
    Q8WXU2-1-unknown MPLQVS... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt73481

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...TELKS 420 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)