TopFIND 4.0

Q91WE6: Threonylcarbamoyladenosine tRNA methylthiotransferase

General Information

Protein names
- Threonylcarbamoyladenosine tRNA methylthiotransferase
- 2.8.4.5 {ECO:0000269|PubMed:20584901}
- CDK5 regulatory subunit-associated protein 1-like 1
- tRNA-t(6)A37 methylthiotransferase
Gene names Cdkal1
Organism Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID Q91WE6

1

N-termini

2

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MPSASCDVLL DDIEDIISQE DSKPQDRQFS RKHVFPKVRR RNTQKYLQEE PRPPSDSTIP 
        70         80         90        100        110        120 
GIQKIWIRTW GCSHNNSDGE YMAGQLAAYG YKITENASDA DLWLLNSCTV KNPAEDHFRN 
       130        140        150        160        170        180 
SIKKAQEENK KVVLAGCVPQ AQPRQDYLKG LSIIGVQQID RVVEVVEETI KGHSVRLLGQ 
       190        200        210        220        230        240 
KKDNGKRLGG ARLDLPKIRK NPLIEIISIN TGCLNACTYC KTKHARGNLA SYPIDELVER 
       250        260        270        280        290        300 
AKQSFQEGVC EIWLTSEDTG AYGRDIGTDL PTLLWKLVEV IPEGAMLRLG MTNPPYILEH 
       310        320        330        340        350        360 
LEEMAKILNH PRVYAFLHIP VQSASDSVLM DMKREYCVAD FKRVVDFLKE KVPGITIATD 
       370        380        390        400        410        420 
IICGFPGETD QDFQETVKLV EEYKFPSLFI NQFYPRPGTP AAKAEQVPAH VKKQRTKDLS 
       430        440        450        460        470        480 
RVFHSYNPYD HKIGERQQVL VTEESFDSKF YVAHNRFYEQ VLVPKNPAFM GKMVEVDIYE 
       490        500        510        520        530        540 
SGKHFLKGQP VSETRVYTPS ISKPLAKGEV SGLTKEFRNR LGNHPNGTSD TCPATQHGSA 
       550        560        570    
YSRMVLQMSQ YDCALKVATG LALLALLLHF WPDSLLTM

Isoforms

- Isoform 2 of Threonylcarbamoyladenosine tRNA methylthiotransferase - Isoform 3 of Threonylcarbamoyladenosine tRNA methylthiotransferase - Isoform 4 of Threonylcarbamoyladenosine tRNA methylthiotransferase - Isoform 5 of Threonylcarbamoyladenosine tRNA methylthiotransferase

Sequence View

        10         20         30         40         50         60 
MPSASCDVLL DDIEDIISQE DSKPQDRQFS RKHVFPKVRR RNTQKYLQEE PRPPSDSTIP 
        70         80         90        100        110        120 
GIQKIWIRTW GCSHNNSDGE YMAGQLAAYG YKITENASDA DLWLLNSCTV KNPAEDHFRN 
       130        140        150        160        170        180 
SIKKAQEENK KVVLAGCVPQ AQPRQDYLKG LSIIGVQQID RVVEVVEETI KGHSVRLLGQ 
       190        200        210        220        230        240 
KKDNGKRLGG ARLDLPKIRK NPLIEIISIN TGCLNACTYC KTKHARGNLA SYPIDELVER 
       250        260        270        280        290        300 
AKQSFQEGVC EIWLTSEDTG AYGRDIGTDL PTLLWKLVEV IPEGAMLRLG MTNPPYILEH 
       310        320        330        340        350        360 
LEEMAKILNH PRVYAFLHIP VQSASDSVLM DMKREYCVAD FKRVVDFLKE KVPGITIATD 
       370        380        390        400        410        420 
IICGFPGETD QDFQETVKLV EEYKFPSLFI NQFYPRPGTP AAKAEQVPAH VKKQRTKDLS 
       430        440        450        460        470        480 
RVFHSYNPYD HKIGERQQVL VTEESFDSKF YVAHNRFYEQ VLVPKNPAFM GKMVEVDIYE 
       490        500        510        520        530        540 
SGKHFLKGQP VSETRVYTPS ISKPLAKGEV SGLTKEFRNR LGNHPNGTSD TCPATQHGSA 
       550        560        570    
YSRMVLQMSQ YDCALKVATG LALLALLLHF WPDSLLTM         10         20         30         40         50         60 
MPSASCDVLL DDIEDIISQE DSKPQDRQFS RKHVFPKVRR RNTQKYLQEE PRPPSDSTIP 
        70         80         90        100        110        120 
GIQKIWIRTW GCSHNNSDGE YMAGQLAAYG YKITENASDA DLWLLNSCTV KNPAEDHFRN 
       130        140        150        160        170        180 
SIKKAQEENK KVVLAGCVPQ AQPRQDYLKG LSIIGVQQID RVVEVVEETI KGHSVRLLGQ 
       190        200        210        220        230        240 
KKDNGKRLGG ARLDLPKIRK NPLIEIISIN TGCLNACTYC KTKHARGNLA SYPIDELVER 
       250        260        270        280        290        300 
AKQSFQEGVC EIWLTSEDTG AYGRDIGTDL PTLLWKLVEV IPEGAMLRLG MTNPPYILEH 
       310        320        330        340        350        360 
LEEMAKILNH PRVYAFLHIP VQSASDSVLM DMKREYCVAD FKRVVDFLKE KVPGITIATD 
       370        380        390        400        410        420 
IICGFPGETD QDFQETVKLV EEYKFPSLFI NQFYPRPGTP AAKAEQVPAH VKKQRTKDLS 
       430        440        450        460        470        480 
RVFHSYNPYD HKIGERQQVL VTEESFDSKF YVAHNRFYEQ VLVPKNPAFM GKMVEVDIYE 
       490        500        510        520        530        540 
SGKHFLKGQP VSETRVYTPS ISKPLAKGEV SGLTKEFRNR LGNHPNGTSD TCPATQHGSA 
       550        560        570    
YSRMVLQMSQ YDCALKVATG LALLALLLHF WPDSLLTM         10         20         30         40         50         60 
MPSASCDVLL DDIEDIISQE DSKPQDRQFS RKHVFPKVRR RNTQKYLQEE PRPPSDSTIP 
        70         80         90        100        110        120 
GIQKIWIRTW GCSHNNSDGE YMAGQLAAYG YKITENASDA DLWLLNSCTV KNPAEDHFRN 
       130        140        150        160        170        180 
SIKKAQEENK KVVLAGCVPQ AQPRQDYLKG LSIIGVQQID RVVEVVEETI KGHSVRLLGQ 
       190        200        210        220        230        240 
KKDNGKRLGG ARLDLPKIRK NPLIEIISIN TGCLNACTYC KTKHARGNLA SYPIDELVER 
       250        260        270        280        290        300 
AKQSFQEGVC EIWLTSEDTG AYGRDIGTDL PTLLWKLVEV IPEGAMLRLG MTNPPYILEH 
       310        320        330        340        350        360 
LEEMAKILNH PRVYAFLHIP VQSASDSVLM DMKREYCVAD FKRVVDFLKE KVPGITIATD 
       370        380        390        400        410        420 
IICGFPGETD QDFQETVKLV EEYKFPSLFI NQFYPRPGTP AAKAEQVPAH VKKQRTKDLS 
       430        440        450        460        470        480 
RVFHSYNPYD HKIGERQQVL VTEESFDSKF YVAHNRFYEQ VLVPKNPAFM GKMVEVDIYE 
       490        500        510        520        530        540 
SGKHFLKGQP VSETRVYTPS ISKPLAKGEV SGLTKEFRNR LGNHPNGTSD TCPATQHGSA 
       550        560        570    
YSRMVLQMSQ YDCALKVATG LALLALLLHF WPDSLLTM         10         20         30         40         50         60 
MPSASCDVLL DDIEDIISQE DSKPQDRQFS RKHVFPKVRR RNTQKYLQEE PRPPSDSTIP 
        70         80         90        100        110        120 
GIQKIWIRTW GCSHNNSDGE YMAGQLAAYG YKITENASDA DLWLLNSCTV KNPAEDHFRN 
       130        140        150        160        170        180 
SIKKAQEENK KVVLAGCVPQ AQPRQDYLKG LSIIGVQQID RVVEVVEETI KGHSVRLLGQ 
       190        200        210        220        230        240 
KKDNGKRLGG ARLDLPKIRK NPLIEIISIN TGCLNACTYC KTKHARGNLA SYPIDELVER 
       250        260        270        280        290        300 
AKQSFQEGVC EIWLTSEDTG AYGRDIGTDL PTLLWKLVEV IPEGAMLRLG MTNPPYILEH 
       310        320        330        340        350        360 
LEEMAKILNH PRVYAFLHIP VQSASDSVLM DMKREYCVAD FKRVVDFLKE KVPGITIATD 
       370        380        390        400        410        420 
IICGFPGETD QDFQETVKLV EEYKFPSLFI NQFYPRPGTP AAKAEQVPAH VKKQRTKDLS 
       430        440        450        460        470        480 
RVFHSYNPYD HKIGERQQVL VTEESFDSKF YVAHNRFYEQ VLVPKNPAFM GKMVEVDIYE 
       490        500        510        520        530        540 
SGKHFLKGQP VSETRVYTPS ISKPLAKGEV SGLTKEFRNR LGNHPNGTSD TCPATQHGSA 
       550        560        570    
YSRMVLQMSQ YDCALKVATG LALLALLLHF WPDSLLTM



Filter Information:


(REFRESH)

Directness:


Physiological Relevance:


Evidence Codes:


Methodology:


Perturbation of System:


Biological System:


Protease Assignment Confidence:


Evidence Names:


Database:


Lab:



Protein Neighborhood

Domains & Features

1 N-termini - 2 C-termini - 0 Cleavages - 0 Substrates

N-termini

C-termini

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)