Q91WG8: Bifunctional UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase

General Information

Protein names	- Bifunctional UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase - UDP-GlcNAc-2-epimerase/ManAc kinase - UDP-N-acetylglucosamine 2-epimerase (hydrolyzing) - 3.2.1.183 - UDP-GlcNAc-2-epimerase - Uridine diphosphate-N-acetylglucosamine-2-epimerase - N-acetylmannosamine kinase - 2.7.1.60 - ManAc kinase
Gene names	Gne
Organism	Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID	Q91WG8

1 N-termini

6 C-termini

0 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MEKNGNNRKL RVCVATCNRA DYSKLAPIMF GIKTEPAFFE LDVVVLGSHL IDDYGNTYRM
        70         80         90        100        110        120
IEQDDFDINT RLHTIVRGED EAAMVESVGL ALVKLPDVLN RLKPDIMIVH GDRFDALALA
       130        140        150        160        170        180
TSAALMNIRI LHIEGGEVSG TIDDSIRHAI TKLAHYHVCC TRSAEQHLIS MCEDHDRILL
       190        200        210        220        230        240
AGCPSYDKLL SAKNKDYMSI IRMWLGDDVK CKDYIVALQH PVTTDIKHSI KMFELTLDAL
       250        260        270        280        290        300
ISFNKRTLVL FPNIDAGSKE MVRVMRKKGI EHHPNFRAVK HVPFDQFIQL VAHAGCMIGN
       310        320        330        340        350        360
SSCGVREVGA FGTPVINLGT RQIGRETGEN VLHVRDADTQ DKILQALHLQ FGKQYPCSKI
       370        380        390        400        410        420
YGDGNAVPRI LKFLKSIDLQ EPLQKKFCFP PVKENISQDI DHILETLSAL AVDLGGTNLR
       430        440        450        460        470        480
VAIVSMKGEI VKKYTQFNPK TYEERISLIL QMCVEAAAEA VKLNCRILGV GISTGGRVNP
       490        500        510        520        530        540
QEGVVLHSTK LIQEWNSVDL RTPLSDTLHL PVWVDNDGNC AAMAERKFGQ GKGQENFVTL
       550        560        570        580        590        600
ITGTGIGGGI IHQHELIHGS SFCAAELGHL VVSLDGPDCS CGSHGCIEAY ASGMALQREA
       610        620        630        640        650        660
KKLHDEDLLL VEGMSVPKDE AVGALHLIQA AKLGNVKAQS ILRTAGTALG LGVVNILHTM
       670        680        690        700        710        720
NPSLVILSGV LASHYIHIVK DVIRQQALSS VQDVDVVVSD LVDPALLGAA SMVLDYTTRR

IH

Isoforms

Sequence View

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(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

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Protein Neighborhood

Domains & Features

1 N-termini - 6 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
Q91WG8-1-unknown	MEKNGN...	1		inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...GLALVK	93	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSMUSP00000122793
...LVKLPD	96	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSMUSP00000115858
...RILHIE	133	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSMUSP00000133440
...SMCEDH	174	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSMUSP00000118443
...IQLVAH	292	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSMUSP00000134406
...TRRIH	722	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)