TopFIND 4.0

Q91WP0: Mannan-binding lectin serine protease 2

General Information

Protein names
- Mannan-binding lectin serine protease 2
- 3.4.21.104
- MBL-associated serine protease 2
- Mannose-binding protein-associated serine protease 2
- MASP-2
- Mannan-binding lectin serine protease 2 A chain
- Mannan-binding lectin serine protease 2 B chain
Gene names Masp2
Organism Mus musculus
Protease Family
Protease ID S01.229
Chromosome location
UniProt ID Q91WP0

3

N-termini

2

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MRLLIFLGLL WSLVATLLGS KWPEPVFGRL VSPGFPEKYA DHQDRSWTLT APPGYRLRLY 
        70         80         90        100        110        120 
FTHFDLELSY RCEYDFVKLS SGTKVLATLC GQESTDTEQA PGNDTFYSLG PSLKVTFHSD 
       130        140        150        160        170        180 
YSNEKPFTGF EAFYAAEDVD ECRVSLGDSV PCDHYCHNYL GGYYCSCRAG YVLHQNKHTC 
       190        200        210        220        230        240 
SALCSGQVFT GRSGYLSSPE YPQPYPKLSS CTYSIRLEDG FSVILDFVES FDVETHPEAQ 
       250        260        270        280        290        300 
CPYDSLKIQT DKGEHGPFCG KTLPPRIETD SHKVTITFAT DESGNHTGWK IHYTSTARPC 
       310        320        330        340        350        360 
PDPTAPPNGS ISPVQAIYVL KDRFSVFCKT GFELLQGSVP LKSFTAVCQK DGSWDRPMPE 
       370        380        390        400        410        420 
CSIIDCGPPD DLPNGHVDYI TGPEVTTYKA VIQYSCEETF YTMSSNGKYV CEADGFWTSS 
       430        440        450        460        470        480 
KGEKLPPVCE PVCGLSTHTI GGRIVGGQPA KPGDFPWQVL LLGQTTAAAG ALIHDNWVLT 
       490        500        510        520        530        540 
AAHAVYEKRM AASSLNIRMG ILKRLSPHYT QAWPEEIFIH EGYTHGAGFD NDIALIKLKN 
       550        560        570        580        590        600 
KVTINGSIMP VCLPRKEAAS LMRTDFTGTV AGWGLTQKGL LARNLMFVDI PIADHQKCTA 
       610        620        630        640        650        660 
VYEKLYPGVR VSANMLCAGL ETGGKDSCRG DSGGALVFLD NETQRWFVGG IVSWGSINCG 
       670        680    
AADQYGVYTK VINYIPWIEN IISNF

Isoforms

- Isoform 2 of Mannan-binding lectin serine protease 2

Sequence View

        10         20         30         40         50         60 
MRLLIFLGLL WSLVATLLGS KWPEPVFGRL VSPGFPEKYA DHQDRSWTLT APPGYRLRLY 
        70         80         90        100        110        120 
FTHFDLELSY RCEYDFVKLS SGTKVLATLC GQESTDTEQA PGNDTFYSLG PSLKVTFHSD 
       130        140        150        160        170        180 
YSNEKPFTGF EAFYAAEDVD ECRVSLGDSV PCDHYCHNYL GGYYCSCRAG YVLHQNKHTC 
       190        200        210        220        230        240 
SALCSGQVFT GRSGYLSSPE YPQPYPKLSS CTYSIRLEDG FSVILDFVES FDVETHPEAQ 
       250        260        270        280        290        300 
CPYDSLKIQT DKGEHGPFCG KTLPPRIETD SHKVTITFAT DESGNHTGWK IHYTSTARPC 
       310        320        330        340        350        360 
PDPTAPPNGS ISPVQAIYVL KDRFSVFCKT GFELLQGSVP LKSFTAVCQK DGSWDRPMPE 
       370        380        390        400        410        420 
CSIIDCGPPD DLPNGHVDYI TGPEVTTYKA VIQYSCEETF YTMSSNGKYV CEADGFWTSS 
       430        440        450        460        470        480 
KGEKLPPVCE PVCGLSTHTI GGRIVGGQPA KPGDFPWQVL LLGQTTAAAG ALIHDNWVLT 
       490        500        510        520        530        540 
AAHAVYEKRM AASSLNIRMG ILKRLSPHYT QAWPEEIFIH EGYTHGAGFD NDIALIKLKN 
       550        560        570        580        590        600 
KVTINGSIMP VCLPRKEAAS LMRTDFTGTV AGWGLTQKGL LARNLMFVDI PIADHQKCTA 
       610        620        630        640        650        660 
VYEKLYPGVR VSANMLCAGL ETGGKDSCRG DSGGALVFLD NETQRWFVGG IVSWGSINCG 
       670        680    
AADQYGVYTK VINYIPWIEN IISNF



Filter Information:


(REFRESH)

Directness:


Physiological Relevance:


Evidence Codes:


Methodology:


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Protease Assignment Confidence:


Evidence Names:


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Protein Neighborhood

Domains & Features

3 N-termini - 2 C-termini - 0 Cleavages - 0 Substrates

N-termini

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...TIGGRI 443 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    ...IISNF 685 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)