TopFIND 4.0

Q91WT9: Cystathionine beta-synthase {ECO:0000305}

General Information

Protein names
- Cystathionine beta-synthase {ECO:0000305}
- 4.2.1.22 {ECO:0000250|UniProtKB:P35520}
- Beta-thionase
- Serine sulfhydrase
Gene names Cbs
Organism Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID Q91WT9

2

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MPSGTSQCED GSAGGFQHLD MHSEKRQLEK GPSGDKDRVW IRPDTPSRCT WQLGRAMADS 
        70         80         90        100        110        120 
PHYHTVLTKS PKILPDILRK IGNTPMVRIN KISKNAGLKC ELLAKCEFFN AGGSVKDRIS 
       130        140        150        160        170        180 
LRMIEDAERA GNLKPGDTII EPTSGNTGIG LALAAAVKGY RCIIVMPEKM SMEKVDVLRA 
       190        200        210        220        230        240 
LGAEIVRTPT NARFDSPESH VGVAWRLKNE IPNSHILDQY RNASNPLAHY DDTAEEILQQ 
       250        260        270        280        290        300 
CDGKLDMLVA SAGTGGTITG IARKLKEKCP GCKIIGVDPE GSILAEPEEL NQTEQTAYEV 
       310        320        330        340        350        360 
EGIGYDFIPT VLDRAVVDKW FKSNDEDSFA FARMLIAQEG LLCGGSSGSA MAVAVKAARE 
       370        380        390        400        410        420 
LQEGQRCVVI LPDSVRNYMS KFLSDKWMLQ KGFMKEELSV KRPWWWRLRV QELSLSAPLT 
       430        440        450        460        470        480 
VLPTVTCEDT IAILREKGFD QAPVVNESGA ILGMVTLGNM LSSLLAGKVR PSDEVCKVLY 
       490        500        510        520        530        540 
KQFKPIHLTD TLGTLSHILE MDHFALVVHE QIQSRDQAWS GVVGGPTDCS NGMSSKQQMV 
       550        560    
FGVVTAIDLL NFVAAREQTQ T

Isoforms

- Isoform 2 of Cystathionine beta-synthase

Sequence View

        10         20         30         40         50         60 
MPSGTSQCED GSAGGFQHLD MHSEKRQLEK GPSGDKDRVW IRPDTPSRCT WQLGRAMADS 
        70         80         90        100        110        120 
PHYHTVLTKS PKILPDILRK IGNTPMVRIN KISKNAGLKC ELLAKCEFFN AGGSVKDRIS 
       130        140        150        160        170        180 
LRMIEDAERA GNLKPGDTII EPTSGNTGIG LALAAAVKGY RCIIVMPEKM SMEKVDVLRA 
       190        200        210        220        230        240 
LGAEIVRTPT NARFDSPESH VGVAWRLKNE IPNSHILDQY RNASNPLAHY DDTAEEILQQ 
       250        260        270        280        290        300 
CDGKLDMLVA SAGTGGTITG IARKLKEKCP GCKIIGVDPE GSILAEPEEL NQTEQTAYEV 
       310        320        330        340        350        360 
EGIGYDFIPT VLDRAVVDKW FKSNDEDSFA FARMLIAQEG LLCGGSSGSA MAVAVKAARE 
       370        380        390        400        410        420 
LQEGQRCVVI LPDSVRNYMS KFLSDKWMLQ KGFMKEELSV KRPWWWRLRV QELSLSAPLT 
       430        440        450        460        470        480 
VLPTVTCEDT IAILREKGFD QAPVVNESGA ILGMVTLGNM LSSLLAGKVR PSDEVCKVLY 
       490        500        510        520        530        540 
KQFKPIHLTD TLGTLSHILE MDHFALVVHE QIQSRDQAWS GVVGGPTDCS NGMSSKQQMV 
       550        560    
FGVVTAIDLL NFVAAREQTQ T



Filter Information:


(REFRESH)

Directness:


Physiological Relevance:


Evidence Codes:


Methodology:


Perturbation of System:


Biological System:


Protease Assignment Confidence:


Evidence Names:


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Lab:



Protein Neighborhood

Domains & Features

2 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...EQTQT 561 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    ...EQTQT 561 inferred from isoform by sequence similarity unknown TopFIND inferred from TCt65097

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)