TopFIND 4.0

Q91X46: Rho guanine nucleotide exchange factor 3

General Information

Protein names
- Rho guanine nucleotide exchange factor 3
Gene names Arhgef3
Organism Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID Q91X46

1

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MVAKDYPFYL TVKRANCSLE APLGSGVAKD EEPSNKRVKP LSRVTSLANL IPPVKTTPLK 
        70         80         90        100        110        120 
RFSQTLQRSI SFRSESRPDI LAPRAWSRNA TSSSTKRRDS KLWSETFDVC VNQVLTAKEI 
       130        140        150        160        170        180 
KRQEAIFELS QGEEDLIEDL KLAKKAYHDP MLKLSIMTEQ ELNQIFGTLD SLIPLHEELL 
       190        200        210        220        230        240 
SQLRDVRKPD GSTEHVGPIL VGWLPCLSSY DSYCSNQVAA KALLDHKKQD HRVQDFLQRC 
       250        260        270        280        290        300 
LESPFSRKLD LWNFLDIPRS RLVKYPLLLR EILRHTPNDN PDQQHLEEAI NIIQGIVAEI 
       310        320        330        340        350        360 
NTKTGESECR YYKERLLYLE EGQKDSLIDS SRVLCCHGEL KNNRGVKLHV FLFQEVLVIT 
       370        380        390        400        410        420 
RAVTHNEQLC YQLYRQPIPV KDLTLEDLQD GEVRLGGSLR GAFSNNERVK NFFRVSFKNG 
       430        440        450        460        470        480 
SQSQTHSLQA NDTFNKQQWL NCIRQAKETV LSAAGQAGLL DSEGLVQGPG TENREPQGET 
       490        500        510        520    
KLEQMDQSDS ESDCSMDTSE VSLECERMEQ TDASCANSRP EESV

Isoforms

- Isoform 2 of Rho guanine nucleotide exchange factor 3 - Isoform 3 of Rho guanine nucleotide exchange factor 3

Sequence View

        10         20         30         40         50         60 
MVAKDYPFYL TVKRANCSLE APLGSGVAKD EEPSNKRVKP LSRVTSLANL IPPVKTTPLK 
        70         80         90        100        110        120 
RFSQTLQRSI SFRSESRPDI LAPRAWSRNA TSSSTKRRDS KLWSETFDVC VNQVLTAKEI 
       130        140        150        160        170        180 
KRQEAIFELS QGEEDLIEDL KLAKKAYHDP MLKLSIMTEQ ELNQIFGTLD SLIPLHEELL 
       190        200        210        220        230        240 
SQLRDVRKPD GSTEHVGPIL VGWLPCLSSY DSYCSNQVAA KALLDHKKQD HRVQDFLQRC 
       250        260        270        280        290        300 
LESPFSRKLD LWNFLDIPRS RLVKYPLLLR EILRHTPNDN PDQQHLEEAI NIIQGIVAEI 
       310        320        330        340        350        360 
NTKTGESECR YYKERLLYLE EGQKDSLIDS SRVLCCHGEL KNNRGVKLHV FLFQEVLVIT 
       370        380        390        400        410        420 
RAVTHNEQLC YQLYRQPIPV KDLTLEDLQD GEVRLGGSLR GAFSNNERVK NFFRVSFKNG 
       430        440        450        460        470        480 
SQSQTHSLQA NDTFNKQQWL NCIRQAKETV LSAAGQAGLL DSEGLVQGPG TENREPQGET 
       490        500        510        520    
KLEQMDQSDS ESDCSMDTSE VSLECERMEQ TDASCANSRP EESV         10         20         30         40         50         60 
MVAKDYPFYL TVKRANCSLE APLGSGVAKD EEPSNKRVKP LSRVTSLANL IPPVKTTPLK 
        70         80         90        100        110        120 
RFSQTLQRSI SFRSESRPDI LAPRAWSRNA TSSSTKRRDS KLWSETFDVC VNQVLTAKEI 
       130        140        150        160        170        180 
KRQEAIFELS QGEEDLIEDL KLAKKAYHDP MLKLSIMTEQ ELNQIFGTLD SLIPLHEELL 
       190        200        210        220        230        240 
SQLRDVRKPD GSTEHVGPIL VGWLPCLSSY DSYCSNQVAA KALLDHKKQD HRVQDFLQRC 
       250        260        270        280        290        300 
LESPFSRKLD LWNFLDIPRS RLVKYPLLLR EILRHTPNDN PDQQHLEEAI NIIQGIVAEI 
       310        320        330        340        350        360 
NTKTGESECR YYKERLLYLE EGQKDSLIDS SRVLCCHGEL KNNRGVKLHV FLFQEVLVIT 
       370        380        390        400        410        420 
RAVTHNEQLC YQLYRQPIPV KDLTLEDLQD GEVRLGGSLR GAFSNNERVK NFFRVSFKNG 
       430        440        450        460        470        480 
SQSQTHSLQA NDTFNKQQWL NCIRQAKETV LSAAGQAGLL DSEGLVQGPG TENREPQGET 
       490        500        510        520    
KLEQMDQSDS ESDCSMDTSE VSLECERMEQ TDASCANSRP EESV



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Evidence Codes:


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Protease Assignment Confidence:


Evidence Names:


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Protein Neighborhood

Domains & Features

1 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    Q91X46-1-unknown MVAKDY... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

C-termini

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)