Q91XQ0: Dynein heavy chain 8, axonemal
| Protein names | - Dynein heavy chain 8, axonemal - Axonemal beta dynein heavy chain 8 - Ciliary dynein heavy chain 8 |
|---|---|
| Gene names | Dnah8 |
| Organism | Mus musculus |
| Protease Family | |
| Protease ID | |
| Chromosome location | |
| UniProt ID | Q91XQ0 |
2
N-termini
1
C-termini
0
Cleavages
0
Substrates
Sequence
10 20 30 40 50 60
MESEEGNAEP PPPSEEAPPP VVEEAPPPLP PEDTAPPPPE EQAPPPEGDA APPPTGDAFQ
70 80 90 100 110 120
LTVEGEAPHP EDPKLLSEQG PATSVTDYRS LIPSDEEVTL PEDEESGQAR VRARHTPRPA
130 140 150 160 170 180
QSVLSDGISQ SSRRPSKFRR SMTGIPNLQE TLKEKQARFR EARENRKMKI GPSHKYIFEV
190 200 210 220 230 240
LGEKLGLDLV TVEELILDCP SLDPFTSFFE KGGCKTLKFL YQEGEVPGFE CGRTITGVPK
250 260 270 280 290 300
GGKMMRIYVD NAAPDKLKGL CLFFVRCRND VAINSKTIHE DVLFSFLDAS KGLLEGIKHM
310 320 330 340 350 360
LKSIFLPAIL ATSNWGALNQ SKQGESEKHI FIETIHRYLA SLDDATISIE GTVMLKKVDN
370 380 390 400 410 420
IDFSKLHTFE EVTAAASSSE MVHQLEEVLM VWYKQIEQVL IESEQMRKEA DDSGPLTELE
430 440 450 460 470 480
HWKRMSAKFN FIIEQIKGSN CKAVINVLNV AHSKLLKNWR DLDARITDSA NESKDNVRYL
490 500 510 520 530 540
YTLEKVCQPL YNYDLVSMAH GIQNLINAIR MIHSVSRYYN TSERMTSLFI KVTNQMVTAC
550 560 570 580 590 600
KAYITDGGTN HVWDQETPAV LKKIQDCIFL FKEYQASFHK TRKQILESSG EKSFEVSEMY
610 620 630 640 650 660
IFGKFEAFCK RLEKITEMIT IVQTYSALSN STIEGIDILG IKFKNIYQGI KKNQYDILDP
670 680 690 700 710 720
RRTEFDTDFT EFMGKINILE IQIQAFMNST FGKILSSQQA LQLLQRFQKL NIPCLHLEIN
730 740 750 760 770 780
HTIERILQCY VAELEFTKKL YLSQKDDPPL ARNMPPIAGK ILWVRQLFRR INEPINYFFK
790 800 810 820 830 840
NSDILSSTEG KAVIRQYNRI AYVLVEFEVA YHTAWFKEVS QLQYALQATL FVRHPETGKL
850 860 870 880 890 900
LVNFDPKILE VVRETKCMIK MKLDVPEQAK NLLKLESKLK ADKLYLQGLL QYYDDLCQEV
910 920 930 940 950 960
PSVFVNLMTP KMKKVESVLR QGLTVLTWSS LMLESFFKEV ESVLDMFNQL LKKVNDLCEM
970 980 990 1000 1010 1020
HIDTVLKEIA KTLLISLSDS GTTKVEDMLT LNETYTKECA DILNHKSRHV EEAVKELILI
1030 1040 1050 1060 1070 1080
FEQIYEVKYT GKAAKSVKEQ RKRVVFGSEA EETEGLDFES TTMEVDTNDK EDEFKKECKE
1090 1100 1110 1120 1130 1140
VYAFFSHQLL DSLQKATRLS LDTMKRRIFV GSQGRRRSED IVSFIKTEVH LAIPNVVMVP
1150 1160 1170 1180 1190 1200
SLDDIQQAIN RMIQLTLEVS RGVAHWGQQQ VRQIKSFQNN SRGSDQPPAS GKPLKKEERS
1210 1220 1230 1240 1250 1260
FEETIPARKL KNFYPGVAEH KDISKLVLLL SSSVNSLRKA ATEALQDFQK YKTLWIEDRH
1270 1280 1290 1300 1310 1320
VKVKEFLANN PSLTEIRSEI LHYATLEQEI KELKPIIVVG SLELHTEPMK LALSIEAKAW
1330 1340 1350 1360 1370 1380
KMLLCRYLNE EYKKKMSDMI TFINEYLKKL SRPIRDLDDV RFAMEALSCI RDNEIQMDMT
1390 1400 1410 1420 1430 1440
LGPIEEAYGI LNRFEVKVTK EESEGVDTLR YSFNKLQSKA VSVQGELVKV QPKFKSNLLE
1450 1460 1470 1480 1490 1500
SVKVFCEDVI NFTEAYETEG PMVPNIPPQE ASNRLQIFQA NFDDLWRKFV TYSSGEQLFG
1510 1520 1530 1540 1550 1560
LPVTDYEVLH KTRKELNLLQ KLYGLYDTVM GSISGYYEIL WGDVDIEKIN AELQEFQNRC
1570 1580 1590 1600 1610 1620
RKLPRALKDW QAFLDLKKRI DDFSESCPLL EMMTNKAMKQ RHWDRISELT GTPFDVESDT
1630 1640 1650 1660 1670 1680
FCLRNIMEAP LLKNKDDIED ICISAIKEKD IEAKLTQVIE NWTYQNLSFA AFKGKGELLL
1690 1700 1710 1720 1730 1740
KGTESGEIIT LMEDSLMVLG SLLSNRYNTP FKKNIQNWVF KLSTSSDIIE EWLIVQNLWV
1750 1760 1770 1780 1790 1800
YLEAVFVGGD IAKQLPQEAK RFQNIDKSWI KIMQRAHENP NVISCCVGDE TMGQLLPHLH
1810 1820 1830 1840 1850 1860
EQLEVCQKSL TGYLEKKRLL FPRFFFVSDP VLLEILGQAS DSHTIQPHLP AVSDNINEVT
1870 1880 1890 1900 1910 1920
FHAKDYDRMT AVISREGEKI MLDTPVMAKG PVEIWLLDLL KVQMSSLHNI IRSAFYQISD
1930 1940 1950 1960 1970 1980
SGFLLLPFLN HFPAQVGLLG IQMLWTHDSE EALNNAKDDR KIMQITNQKF LDILNTLISQ
1990 2000 2010 2020 2030 2040
TTHDLTKFDR VKFETLITIH VHQRDIFDDL VKMHIKSVTD FEWLKQSRFY FKEDLDQTVV
2050 2060 2070 2080 2090 2100
SITDVDFIYQ NEFLGCTDRL VITPLTDRCY ITLAQALGMN MGGAPAGPAG TGKTETTKDM
2110 2120 2130 2140 2150 2160
GRCLGKYVVV FNCSDQMDFR GLGRIFKGLA QSGSWGCFDE FNRIELPVLS VAAQQIYIVL
2170 2180 2190 2200 2210 2220
TARKERKKQF IFSDGDCVDL NPEFGIFLTM NPGYAGRQEL PENLKIQFRT VAMMVPDRQI
2230 2240 2250 2260 2270 2280
IMRVKLASCG FLENVILAQK FYVLYKLCEE QLTKQVHYDF GLRNILSVLR TLGSQKRARP
2290 2300 2310 2320 2330 2340
EDSELSTVMR GLRDMNLSKL VDEDEPLFLS LINDLFPGLQ LDSSTYAELQ SAVDNQVNLE
2350 2360 2370 2380 2390 2400
GLINHPPWNL KLVQLYETSL VRHGLMTLGP SGSGKTTVIT ILMKSLTECG RPHREMRMNP
2410 2420 2430 2440 2450 2460
KAITAPQMFG RLDTATNDWT DGIFSTLWRK TLKAKKGENI FLILDGPVDA IWIENLNSVL
2470 2480 2490 2500 2510 2520
DDNKTLTLAN GDRIPMAPTC KLLFEVHNIE NASPATVSRM GMVYISSSAL SWRPILQAWL
2530 2540 2550 2560 2570 2580
KKRSQQEASV FLSLYDKVFE DAYTYMKLSL NPKMQLLECN YIMQSLNLLE GLIPSKEEGG
2590 2600 2610 2620 2630 2640
VSSGDHLHKL FVFGLMWSLG ALLELDSREK LEVFLRGHGS KLNLPEIPKG SQQTMYEFYV
2650 2660 2670 2680 2690 2700
TDYGDWEHWN KRIQPYFYPT DSIPEYSSIL VPNVDNIRTN FLIDTIAKQH KAVLLTGEQG
2710 2720 2730 2740 2750 2760
TAKTVMVKAY LKKYDPEVQL SKSLNFSSAT EPMMFQRTIE SYVDKRMGST YGPPGGRKMT
2770 2780 2790 2800 2810 2820
VFIDDINMPV INEWGDQITN EIVRQMMEME GMYSLDKPGD FTTIVDVQLI AAMIHPGGGR
2830 2840 2850 2860 2870 2880
NDIPQRLKRQ FTVFNCTLPS NTSIDKIFGI IGCGYFDPCR KFRPEICDMV GNLVSVSRVL
2890 2900 2910 2920 2930 2940
WQWTKVKMLP TPSKFHYIFN LRDLSRIWQG MLTVKAEECS SIPILLSLFK HECNRVIADR
2950 2960 2970 2980 2990 3000
FITPDDEQWF NSQLIRAVEE NISPEVAANI LPEPYFVDFL RDMPEPTGDE PEDTMFEVPK
3010 3020 3030 3040 3050 3060
IYELVPSFEF LSEKLQFYQR QFNEIIRGTS LDLVFFKDAM THLVKISRII RTSCGNALLV
3070 3080 3090 3100 3110 3120
GVGGSGKQSL SKLASFIAGY QIFQITLTRS YNVSNLIEDL KNLYKVAGAE GKGITFIFTD
3130 3140 3150 3160 3170 3180
NEIKDEAFLE YLNNLLSSGE ISNLFARDEM DEITQGLISV MKRELPRHPP TFDNLYEYFI
3190 3200 3210 3220 3230 3240
TRSRKNLHVV LCFSPVGEKF RARSLKFPGL ISGCTMDWFS RWPKEALIAV ASYFLLDYNI
3250 3260 3270 3280 3290 3300
VCSIETKRHV VETMGLFHDM VSESCENYFQ RYRRRAHVTP KSYLSFINGY KSIYTDKVKY
3310 3320 3330 3340 3350 3360
INEQAERMNI GLDKLMEASE SVAKLSQDLA VKEKELAVAS IKADEVLAEV TVSAQASAKV
3370 3380 3390 3400 3410 3420
KNEVQEVKDK AQKIVDEIDS EKVKAETKLE AAKPALEEAE AALNTIKPND IATVRKLAKP
3430 3440 3450 3460 3470 3480
PHLIMRIMDC VLLLFQKKID PVTMDPEKPC CKPSWGESLK LMSATGFLFS LQQFPKDTIN
3490 3500 3510 3520 3530 3540
EETVELLQPY FNMDDYTFES AKKVCGNVAG LLSWTLAMVI FYGINREVLP LKANLAKQEG
3550 3560 3570 3580 3590 3600
RLAVANVELG KAQALLDEKQ AELDKVQAKF DAAMKEKMDL LNDADMCRKK MQAASTLIDG
3610 3620 3630 3640 3650 3660
LSGEKVRWTQ QSKEFKTQIN RLVGDVLLCT GFLSYLGPFN QIFRNYLLKD QWELELKARK
3670 3680 3690 3700 3710 3720
IPFTENLNLI AMLVDPPTIG EWGLQGLPGD DLSIQNGIIV TKATRYPLLI DPQTQGKTWI
3730 3740 3750 3760 3770 3780
KSKEKENDLQ VTSLNHKYFR THLEDSLSLG RPLLIEDIRE ELDPALDNVL EKNFIKSGTA
3790 3800 3810 3820 3830 3840
FKVKVGDKEC DIMDTFKLYI TTKLPNPAFT PEINAKTSVI DFTVTMKGLE NQLLRRVILT
3850 3860 3870 3880 3890 3900
EKQELESERV KLLEDVTFNK RKMKELEDNL LYKLSATKGS LVDDESLIGV LRITKQTAAE
3910 3920 3930 3940 3950 3960
VSEKLHVAAE TEIKINTAQE EFRPAATRGS ILYFLITEMS MVNIMYQTSL AQFLKLFDQS
3970 3980 3990 4000 4010 4020
MARSEKSPLP QKRITNIIEY LTYEVFTYSV RGLYENHKFL FVLLMTLKID LQRGTVKHKE
4030 4040 4050 4060 4070 4080
FQALIKGGAA LDLKACPPKP FRWILDMTWL NLVELSKLPQ FAEIMNQISR NEKGWKNWFD
4090 4100 4110 4120 4130 4140
KDAPEEEIIP DGYNDSLDTC RKLLLIRSWC PDRTVFQARK YIADSLEEKY TEPVILNLEK
4150 4160 4170 4180 4190 4200
TWEESDTHTP LICFLSMGSD PTIQIDALAK KLKLECRTIS MGQGQEVHAR KLIQLSMQQG
4210 4220 4230 4240 4250 4260
GWVLLQNCHL GLEFMEELLE MLMVTETTED SFRVWITTEP HDRFPITLLQ TSIKFTNEPP
4270 4280 4290 4300 4310 4320
QGVRAGLKRT FAGINQDLLD ISNLPMWKPM LYTVAFLHST VQERRKFGPL GWNIPYEFNS
4330 4340 4350 4360 4370 4380
ADFSASVQFI QNHLDECDIK KGVSWSTVRY MIGEVQYGGR VTDDFDKRLL NCFARVWFSE
4390 4400 4410 4420 4430 4440
KMFEPSFCFY TGYKIPICKT LDQYFEFIQS LPSLDNPEVF GLHPNADITY QSNTASDVLE
4450 4460 4470 4480 4490 4500
TITNIQPKES GGGVGETREA IVYRLSEDML SKLPPNYVPH EVKARLMKMG HLNSMNIFLR
4510 4520 4530 4540 4550 4560
QEIDRMQKVI SILRSSLSDL KLAIEGTIIM SENLRDALDN MYDARIPQLW KRVSWDSSTL
4570 4580 4590 4600 4610 4620
GFWFTELLER NAQFSTWIFE GRPNVFWMTG FFNPQGFLTA MRQEVTRAHK GWALDTVTIH
4630 4640 4650 4660 4670 4680
NEVLRQTKEE IITPPAEGVY IYGLYMDGAS WDRRNGKLTE STPKVLFTQL PVLHIFAINS
4690 4700 4710 4720 4730
TAPKDPKLYV CPIYKKPRRT DLTFITVVYL RTVLSPDHWI LRGVALLCDI K
Isoforms
- Isoform 2 of Dynein heavy chain 8, axonemal - Isoform 3 of Dynein heavy chain 8, axonemalSequence View
10 20 30 40 50 60
MESEEGNAEP PPPSEEAPPP VVEEAPPPLP PEDTAPPPPE EQAPPPEGDA APPPTGDAFQ
70 80 90 100 110 120
LTVEGEAPHP EDPKLLSEQG PATSVTDYRS LIPSDEEVTL PEDEESGQAR VRARHTPRPA
130 140 150 160 170 180
QSVLSDGISQ SSRRPSKFRR SMTGIPNLQE TLKEKQARFR EARENRKMKI GPSHKYIFEV
190 200 210 220 230 240
LGEKLGLDLV TVEELILDCP SLDPFTSFFE KGGCKTLKFL YQEGEVPGFE CGRTITGVPK
250 260 270 280 290 300
GGKMMRIYVD NAAPDKLKGL CLFFVRCRND VAINSKTIHE DVLFSFLDAS KGLLEGIKHM
310 320 330 340 350 360
LKSIFLPAIL ATSNWGALNQ SKQGESEKHI FIETIHRYLA SLDDATISIE GTVMLKKVDN
370 380 390 400 410 420
IDFSKLHTFE EVTAAASSSE MVHQLEEVLM VWYKQIEQVL IESEQMRKEA DDSGPLTELE
430 440 450 460 470 480
HWKRMSAKFN FIIEQIKGSN CKAVINVLNV AHSKLLKNWR DLDARITDSA NESKDNVRYL
490 500 510 520 530 540
YTLEKVCQPL YNYDLVSMAH GIQNLINAIR MIHSVSRYYN TSERMTSLFI KVTNQMVTAC
550 560 570 580 590 600
KAYITDGGTN HVWDQETPAV LKKIQDCIFL FKEYQASFHK TRKQILESSG EKSFEVSEMY
610 620 630 640 650 660
IFGKFEAFCK RLEKITEMIT IVQTYSALSN STIEGIDILG IKFKNIYQGI KKNQYDILDP
670 680 690 700 710 720
RRTEFDTDFT EFMGKINILE IQIQAFMNST FGKILSSQQA LQLLQRFQKL NIPCLHLEIN
730 740 750 760 770 780
HTIERILQCY VAELEFTKKL YLSQKDDPPL ARNMPPIAGK ILWVRQLFRR INEPINYFFK
790 800 810 820 830 840
NSDILSSTEG KAVIRQYNRI AYVLVEFEVA YHTAWFKEVS QLQYALQATL FVRHPETGKL
850 860 870 880 890 900
LVNFDPKILE VVRETKCMIK MKLDVPEQAK NLLKLESKLK ADKLYLQGLL QYYDDLCQEV
910 920 930 940 950 960
PSVFVNLMTP KMKKVESVLR QGLTVLTWSS LMLESFFKEV ESVLDMFNQL LKKVNDLCEM
970 980 990 1000 1010 1020
HIDTVLKEIA KTLLISLSDS GTTKVEDMLT LNETYTKECA DILNHKSRHV EEAVKELILI
1030 1040 1050 1060 1070 1080
FEQIYEVKYT GKAAKSVKEQ RKRVVFGSEA EETEGLDFES TTMEVDTNDK EDEFKKECKE
1090 1100 1110 1120 1130 1140
VYAFFSHQLL DSLQKATRLS LDTMKRRIFV GSQGRRRSED IVSFIKTEVH LAIPNVVMVP
1150 1160 1170 1180 1190 1200
SLDDIQQAIN RMIQLTLEVS RGVAHWGQQQ VRQIKSFQNN SRGSDQPPAS GKPLKKEERS
1210 1220 1230 1240 1250 1260
FEETIPARKL KNFYPGVAEH KDISKLVLLL SSSVNSLRKA ATEALQDFQK YKTLWIEDRH
1270 1280 1290 1300 1310 1320
VKVKEFLANN PSLTEIRSEI LHYATLEQEI KELKPIIVVG SLELHTEPMK LALSIEAKAW
1330 1340 1350 1360 1370 1380
KMLLCRYLNE EYKKKMSDMI TFINEYLKKL SRPIRDLDDV RFAMEALSCI RDNEIQMDMT
1390 1400 1410 1420 1430 1440
LGPIEEAYGI LNRFEVKVTK EESEGVDTLR YSFNKLQSKA VSVQGELVKV QPKFKSNLLE
1450 1460 1470 1480 1490 1500
SVKVFCEDVI NFTEAYETEG PMVPNIPPQE ASNRLQIFQA NFDDLWRKFV TYSSGEQLFG
1510 1520 1530 1540 1550 1560
LPVTDYEVLH KTRKELNLLQ KLYGLYDTVM GSISGYYEIL WGDVDIEKIN AELQEFQNRC
1570 1580 1590 1600 1610 1620
RKLPRALKDW QAFLDLKKRI DDFSESCPLL EMMTNKAMKQ RHWDRISELT GTPFDVESDT
1630 1640 1650 1660 1670 1680
FCLRNIMEAP LLKNKDDIED ICISAIKEKD IEAKLTQVIE NWTYQNLSFA AFKGKGELLL
1690 1700 1710 1720 1730 1740
KGTESGEIIT LMEDSLMVLG SLLSNRYNTP FKKNIQNWVF KLSTSSDIIE EWLIVQNLWV
1750 1760 1770 1780 1790 1800
YLEAVFVGGD IAKQLPQEAK RFQNIDKSWI KIMQRAHENP NVISCCVGDE TMGQLLPHLH
1810 1820 1830 1840 1850 1860
EQLEVCQKSL TGYLEKKRLL FPRFFFVSDP VLLEILGQAS DSHTIQPHLP AVSDNINEVT
1870 1880 1890 1900 1910 1920
FHAKDYDRMT AVISREGEKI MLDTPVMAKG PVEIWLLDLL KVQMSSLHNI IRSAFYQISD
1930 1940 1950 1960 1970 1980
SGFLLLPFLN HFPAQVGLLG IQMLWTHDSE EALNNAKDDR KIMQITNQKF LDILNTLISQ
1990 2000 2010 2020 2030 2040
TTHDLTKFDR VKFETLITIH VHQRDIFDDL VKMHIKSVTD FEWLKQSRFY FKEDLDQTVV
2050 2060 2070 2080 2090 2100
SITDVDFIYQ NEFLGCTDRL VITPLTDRCY ITLAQALGMN MGGAPAGPAG TGKTETTKDM
2110 2120 2130 2140 2150 2160
GRCLGKYVVV FNCSDQMDFR GLGRIFKGLA QSGSWGCFDE FNRIELPVLS VAAQQIYIVL
2170 2180 2190 2200 2210 2220
TARKERKKQF IFSDGDCVDL NPEFGIFLTM NPGYAGRQEL PENLKIQFRT VAMMVPDRQI
2230 2240 2250 2260 2270 2280
IMRVKLASCG FLENVILAQK FYVLYKLCEE QLTKQVHYDF GLRNILSVLR TLGSQKRARP
2290 2300 2310 2320 2330 2340
EDSELSTVMR GLRDMNLSKL VDEDEPLFLS LINDLFPGLQ LDSSTYAELQ SAVDNQVNLE
2350 2360 2370 2380 2390 2400
GLINHPPWNL KLVQLYETSL VRHGLMTLGP SGSGKTTVIT ILMKSLTECG RPHREMRMNP
2410 2420 2430 2440 2450 2460
KAITAPQMFG RLDTATNDWT DGIFSTLWRK TLKAKKGENI FLILDGPVDA IWIENLNSVL
2470 2480 2490 2500 2510 2520
DDNKTLTLAN GDRIPMAPTC KLLFEVHNIE NASPATVSRM GMVYISSSAL SWRPILQAWL
2530 2540 2550 2560 2570 2580
KKRSQQEASV FLSLYDKVFE DAYTYMKLSL NPKMQLLECN YIMQSLNLLE GLIPSKEEGG
2590 2600 2610 2620 2630 2640
VSSGDHLHKL FVFGLMWSLG ALLELDSREK LEVFLRGHGS KLNLPEIPKG SQQTMYEFYV
2650 2660 2670 2680 2690 2700
TDYGDWEHWN KRIQPYFYPT DSIPEYSSIL VPNVDNIRTN FLIDTIAKQH KAVLLTGEQG
2710 2720 2730 2740 2750 2760
TAKTVMVKAY LKKYDPEVQL SKSLNFSSAT EPMMFQRTIE SYVDKRMGST YGPPGGRKMT
2770 2780 2790 2800 2810 2820
VFIDDINMPV INEWGDQITN EIVRQMMEME GMYSLDKPGD FTTIVDVQLI AAMIHPGGGR
2830 2840 2850 2860 2870 2880
NDIPQRLKRQ FTVFNCTLPS NTSIDKIFGI IGCGYFDPCR KFRPEICDMV GNLVSVSRVL
2890 2900 2910 2920 2930 2940
WQWTKVKMLP TPSKFHYIFN LRDLSRIWQG MLTVKAEECS SIPILLSLFK HECNRVIADR
2950 2960 2970 2980 2990 3000
FITPDDEQWF NSQLIRAVEE NISPEVAANI LPEPYFVDFL RDMPEPTGDE PEDTMFEVPK
3010 3020 3030 3040 3050 3060
IYELVPSFEF LSEKLQFYQR QFNEIIRGTS LDLVFFKDAM THLVKISRII RTSCGNALLV
3070 3080 3090 3100 3110 3120
GVGGSGKQSL SKLASFIAGY QIFQITLTRS YNVSNLIEDL KNLYKVAGAE GKGITFIFTD
3130 3140 3150 3160 3170 3180
NEIKDEAFLE YLNNLLSSGE ISNLFARDEM DEITQGLISV MKRELPRHPP TFDNLYEYFI
3190 3200 3210 3220 3230 3240
TRSRKNLHVV LCFSPVGEKF RARSLKFPGL ISGCTMDWFS RWPKEALIAV ASYFLLDYNI
3250 3260 3270 3280 3290 3300
VCSIETKRHV VETMGLFHDM VSESCENYFQ RYRRRAHVTP KSYLSFINGY KSIYTDKVKY
3310 3320 3330 3340 3350 3360
INEQAERMNI GLDKLMEASE SVAKLSQDLA VKEKELAVAS IKADEVLAEV TVSAQASAKV
3370 3380 3390 3400 3410 3420
KNEVQEVKDK AQKIVDEIDS EKVKAETKLE AAKPALEEAE AALNTIKPND IATVRKLAKP
3430 3440 3450 3460 3470 3480
PHLIMRIMDC VLLLFQKKID PVTMDPEKPC CKPSWGESLK LMSATGFLFS LQQFPKDTIN
3490 3500 3510 3520 3530 3540
EETVELLQPY FNMDDYTFES AKKVCGNVAG LLSWTLAMVI FYGINREVLP LKANLAKQEG
3550 3560 3570 3580 3590 3600
RLAVANVELG KAQALLDEKQ AELDKVQAKF DAAMKEKMDL LNDADMCRKK MQAASTLIDG
3610 3620 3630 3640 3650 3660
LSGEKVRWTQ QSKEFKTQIN RLVGDVLLCT GFLSYLGPFN QIFRNYLLKD QWELELKARK
3670 3680 3690 3700 3710 3720
IPFTENLNLI AMLVDPPTIG EWGLQGLPGD DLSIQNGIIV TKATRYPLLI DPQTQGKTWI
3730 3740 3750 3760 3770 3780
KSKEKENDLQ VTSLNHKYFR THLEDSLSLG RPLLIEDIRE ELDPALDNVL EKNFIKSGTA
3790 3800 3810 3820 3830 3840
FKVKVGDKEC DIMDTFKLYI TTKLPNPAFT PEINAKTSVI DFTVTMKGLE NQLLRRVILT
3850 3860 3870 3880 3890 3900
EKQELESERV KLLEDVTFNK RKMKELEDNL LYKLSATKGS LVDDESLIGV LRITKQTAAE
3910 3920 3930 3940 3950 3960
VSEKLHVAAE TEIKINTAQE EFRPAATRGS ILYFLITEMS MVNIMYQTSL AQFLKLFDQS
3970 3980 3990 4000 4010 4020
MARSEKSPLP QKRITNIIEY LTYEVFTYSV RGLYENHKFL FVLLMTLKID LQRGTVKHKE
4030 4040 4050 4060 4070 4080
FQALIKGGAA LDLKACPPKP FRWILDMTWL NLVELSKLPQ FAEIMNQISR NEKGWKNWFD
4090 4100 4110 4120 4130 4140
KDAPEEEIIP DGYNDSLDTC RKLLLIRSWC PDRTVFQARK YIADSLEEKY TEPVILNLEK
4150 4160 4170 4180 4190 4200
TWEESDTHTP LICFLSMGSD PTIQIDALAK KLKLECRTIS MGQGQEVHAR KLIQLSMQQG
4210 4220 4230 4240 4250 4260
GWVLLQNCHL GLEFMEELLE MLMVTETTED SFRVWITTEP HDRFPITLLQ TSIKFTNEPP
4270 4280 4290 4300 4310 4320
QGVRAGLKRT FAGINQDLLD ISNLPMWKPM LYTVAFLHST VQERRKFGPL GWNIPYEFNS
4330 4340 4350 4360 4370 4380
ADFSASVQFI QNHLDECDIK KGVSWSTVRY MIGEVQYGGR VTDDFDKRLL NCFARVWFSE
4390 4400 4410 4420 4430 4440
KMFEPSFCFY TGYKIPICKT LDQYFEFIQS LPSLDNPEVF GLHPNADITY QSNTASDVLE
4450 4460 4470 4480 4490 4500
TITNIQPKES GGGVGETREA IVYRLSEDML SKLPPNYVPH EVKARLMKMG HLNSMNIFLR
4510 4520 4530 4540 4550 4560
QEIDRMQKVI SILRSSLSDL KLAIEGTIIM SENLRDALDN MYDARIPQLW KRVSWDSSTL
4570 4580 4590 4600 4610 4620
GFWFTELLER NAQFSTWIFE GRPNVFWMTG FFNPQGFLTA MRQEVTRAHK GWALDTVTIH
4630 4640 4650 4660 4670 4680
NEVLRQTKEE IITPPAEGVY IYGLYMDGAS WDRRNGKLTE STPKVLFTQL PVLHIFAINS
4690 4700 4710 4720 4730
TAPKDPKLYV CPIYKKPRRT DLTFITVVYL RTVLSPDHWI LRGVALLCDI K
10 20 30 40 50 60
MESEEGNAEP PPPSEEAPPP VVEEAPPPLP PEDTAPPPPE EQAPPPEGDA APPPTGDAFQ
70 80 90 100 110 120
LTVEGEAPHP EDPKLLSEQG PATSVTDYRS LIPSDEEVTL PEDEESGQAR VRARHTPRPA
130 140 150 160 170 180
QSVLSDGISQ SSRRPSKFRR SMTGIPNLQE TLKEKQARFR EARENRKMKI GPSHKYIFEV
190 200 210 220 230 240
LGEKLGLDLV TVEELILDCP SLDPFTSFFE KGGCKTLKFL YQEGEVPGFE CGRTITGVPK
250 260 270 280 290 300
GGKMMRIYVD NAAPDKLKGL CLFFVRCRND VAINSKTIHE DVLFSFLDAS KGLLEGIKHM
310 320 330 340 350 360
LKSIFLPAIL ATSNWGALNQ SKQGESEKHI FIETIHRYLA SLDDATISIE GTVMLKKVDN
370 380 390 400 410 420
IDFSKLHTFE EVTAAASSSE MVHQLEEVLM VWYKQIEQVL IESEQMRKEA DDSGPLTELE
430 440 450 460 470 480
HWKRMSAKFN FIIEQIKGSN CKAVINVLNV AHSKLLKNWR DLDARITDSA NESKDNVRYL
490 500 510 520 530 540
YTLEKVCQPL YNYDLVSMAH GIQNLINAIR MIHSVSRYYN TSERMTSLFI KVTNQMVTAC
550 560 570 580 590 600
KAYITDGGTN HVWDQETPAV LKKIQDCIFL FKEYQASFHK TRKQILESSG EKSFEVSEMY
610 620 630 640 650 660
IFGKFEAFCK RLEKITEMIT IVQTYSALSN STIEGIDILG IKFKNIYQGI KKNQYDILDP
670 680 690 700 710 720
RRTEFDTDFT EFMGKINILE IQIQAFMNST FGKILSSQQA LQLLQRFQKL NIPCLHLEIN
730 740 750 760 770 780
HTIERILQCY VAELEFTKKL YLSQKDDPPL ARNMPPIAGK ILWVRQLFRR INEPINYFFK
790 800 810 820 830 840
NSDILSSTEG KAVIRQYNRI AYVLVEFEVA YHTAWFKEVS QLQYALQATL FVRHPETGKL
850 860 870 880 890 900
LVNFDPKILE VVRETKCMIK MKLDVPEQAK NLLKLESKLK ADKLYLQGLL QYYDDLCQEV
910 920 930 940 950 960
PSVFVNLMTP KMKKVESVLR QGLTVLTWSS LMLESFFKEV ESVLDMFNQL LKKVNDLCEM
970 980 990 1000 1010 1020
HIDTVLKEIA KTLLISLSDS GTTKVEDMLT LNETYTKECA DILNHKSRHV EEAVKELILI
1030 1040 1050 1060 1070 1080
FEQIYEVKYT GKAAKSVKEQ RKRVVFGSEA EETEGLDFES TTMEVDTNDK EDEFKKECKE
1090 1100 1110 1120 1130 1140
VYAFFSHQLL DSLQKATRLS LDTMKRRIFV GSQGRRRSED IVSFIKTEVH LAIPNVVMVP
1150 1160 1170 1180 1190 1200
SLDDIQQAIN RMIQLTLEVS RGVAHWGQQQ VRQIKSFQNN SRGSDQPPAS GKPLKKEERS
1210 1220 1230 1240 1250 1260
FEETIPARKL KNFYPGVAEH KDISKLVLLL SSSVNSLRKA ATEALQDFQK YKTLWIEDRH
1270 1280 1290 1300 1310 1320
VKVKEFLANN PSLTEIRSEI LHYATLEQEI KELKPIIVVG SLELHTEPMK LALSIEAKAW
1330 1340 1350 1360 1370 1380
KMLLCRYLNE EYKKKMSDMI TFINEYLKKL SRPIRDLDDV RFAMEALSCI RDNEIQMDMT
1390 1400 1410 1420 1430 1440
LGPIEEAYGI LNRFEVKVTK EESEGVDTLR YSFNKLQSKA VSVQGELVKV QPKFKSNLLE
1450 1460 1470 1480 1490 1500
SVKVFCEDVI NFTEAYETEG PMVPNIPPQE ASNRLQIFQA NFDDLWRKFV TYSSGEQLFG
1510 1520 1530 1540 1550 1560
LPVTDYEVLH KTRKELNLLQ KLYGLYDTVM GSISGYYEIL WGDVDIEKIN AELQEFQNRC
1570 1580 1590 1600 1610 1620
RKLPRALKDW QAFLDLKKRI DDFSESCPLL EMMTNKAMKQ RHWDRISELT GTPFDVESDT
1630 1640 1650 1660 1670 1680
FCLRNIMEAP LLKNKDDIED ICISAIKEKD IEAKLTQVIE NWTYQNLSFA AFKGKGELLL
1690 1700 1710 1720 1730 1740
KGTESGEIIT LMEDSLMVLG SLLSNRYNTP FKKNIQNWVF KLSTSSDIIE EWLIVQNLWV
1750 1760 1770 1780 1790 1800
YLEAVFVGGD IAKQLPQEAK RFQNIDKSWI KIMQRAHENP NVISCCVGDE TMGQLLPHLH
1810 1820 1830 1840 1850 1860
EQLEVCQKSL TGYLEKKRLL FPRFFFVSDP VLLEILGQAS DSHTIQPHLP AVSDNINEVT
1870 1880 1890 1900 1910 1920
FHAKDYDRMT AVISREGEKI MLDTPVMAKG PVEIWLLDLL KVQMSSLHNI IRSAFYQISD
1930 1940 1950 1960 1970 1980
SGFLLLPFLN HFPAQVGLLG IQMLWTHDSE EALNNAKDDR KIMQITNQKF LDILNTLISQ
1990 2000 2010 2020 2030 2040
TTHDLTKFDR VKFETLITIH VHQRDIFDDL VKMHIKSVTD FEWLKQSRFY FKEDLDQTVV
2050 2060 2070 2080 2090 2100
SITDVDFIYQ NEFLGCTDRL VITPLTDRCY ITLAQALGMN MGGAPAGPAG TGKTETTKDM
2110 2120 2130 2140 2150 2160
GRCLGKYVVV FNCSDQMDFR GLGRIFKGLA QSGSWGCFDE FNRIELPVLS VAAQQIYIVL
2170 2180 2190 2200 2210 2220
TARKERKKQF IFSDGDCVDL NPEFGIFLTM NPGYAGRQEL PENLKIQFRT VAMMVPDRQI
2230 2240 2250 2260 2270 2280
IMRVKLASCG FLENVILAQK FYVLYKLCEE QLTKQVHYDF GLRNILSVLR TLGSQKRARP
2290 2300 2310 2320 2330 2340
EDSELSTVMR GLRDMNLSKL VDEDEPLFLS LINDLFPGLQ LDSSTYAELQ SAVDNQVNLE
2350 2360 2370 2380 2390 2400
GLINHPPWNL KLVQLYETSL VRHGLMTLGP SGSGKTTVIT ILMKSLTECG RPHREMRMNP
2410 2420 2430 2440 2450 2460
KAITAPQMFG RLDTATNDWT DGIFSTLWRK TLKAKKGENI FLILDGPVDA IWIENLNSVL
2470 2480 2490 2500 2510 2520
DDNKTLTLAN GDRIPMAPTC KLLFEVHNIE NASPATVSRM GMVYISSSAL SWRPILQAWL
2530 2540 2550 2560 2570 2580
KKRSQQEASV FLSLYDKVFE DAYTYMKLSL NPKMQLLECN YIMQSLNLLE GLIPSKEEGG
2590 2600 2610 2620 2630 2640
VSSGDHLHKL FVFGLMWSLG ALLELDSREK LEVFLRGHGS KLNLPEIPKG SQQTMYEFYV
2650 2660 2670 2680 2690 2700
TDYGDWEHWN KRIQPYFYPT DSIPEYSSIL VPNVDNIRTN FLIDTIAKQH KAVLLTGEQG
2710 2720 2730 2740 2750 2760
TAKTVMVKAY LKKYDPEVQL SKSLNFSSAT EPMMFQRTIE SYVDKRMGST YGPPGGRKMT
2770 2780 2790 2800 2810 2820
VFIDDINMPV INEWGDQITN EIVRQMMEME GMYSLDKPGD FTTIVDVQLI AAMIHPGGGR
2830 2840 2850 2860 2870 2880
NDIPQRLKRQ FTVFNCTLPS NTSIDKIFGI IGCGYFDPCR KFRPEICDMV GNLVSVSRVL
2890 2900 2910 2920 2930 2940
WQWTKVKMLP TPSKFHYIFN LRDLSRIWQG MLTVKAEECS SIPILLSLFK HECNRVIADR
2950 2960 2970 2980 2990 3000
FITPDDEQWF NSQLIRAVEE NISPEVAANI LPEPYFVDFL RDMPEPTGDE PEDTMFEVPK
3010 3020 3030 3040 3050 3060
IYELVPSFEF LSEKLQFYQR QFNEIIRGTS LDLVFFKDAM THLVKISRII RTSCGNALLV
3070 3080 3090 3100 3110 3120
GVGGSGKQSL SKLASFIAGY QIFQITLTRS YNVSNLIEDL KNLYKVAGAE GKGITFIFTD
3130 3140 3150 3160 3170 3180
NEIKDEAFLE YLNNLLSSGE ISNLFARDEM DEITQGLISV MKRELPRHPP TFDNLYEYFI
3190 3200 3210 3220 3230 3240
TRSRKNLHVV LCFSPVGEKF RARSLKFPGL ISGCTMDWFS RWPKEALIAV ASYFLLDYNI
3250 3260 3270 3280 3290 3300
VCSIETKRHV VETMGLFHDM VSESCENYFQ RYRRRAHVTP KSYLSFINGY KSIYTDKVKY
3310 3320 3330 3340 3350 3360
INEQAERMNI GLDKLMEASE SVAKLSQDLA VKEKELAVAS IKADEVLAEV TVSAQASAKV
3370 3380 3390 3400 3410 3420
KNEVQEVKDK AQKIVDEIDS EKVKAETKLE AAKPALEEAE AALNTIKPND IATVRKLAKP
3430 3440 3450 3460 3470 3480
PHLIMRIMDC VLLLFQKKID PVTMDPEKPC CKPSWGESLK LMSATGFLFS LQQFPKDTIN
3490 3500 3510 3520 3530 3540
EETVELLQPY FNMDDYTFES AKKVCGNVAG LLSWTLAMVI FYGINREVLP LKANLAKQEG
3550 3560 3570 3580 3590 3600
RLAVANVELG KAQALLDEKQ AELDKVQAKF DAAMKEKMDL LNDADMCRKK MQAASTLIDG
3610 3620 3630 3640 3650 3660
LSGEKVRWTQ QSKEFKTQIN RLVGDVLLCT GFLSYLGPFN QIFRNYLLKD QWELELKARK
3670 3680 3690 3700 3710 3720
IPFTENLNLI AMLVDPPTIG EWGLQGLPGD DLSIQNGIIV TKATRYPLLI DPQTQGKTWI
3730 3740 3750 3760 3770 3780
KSKEKENDLQ VTSLNHKYFR THLEDSLSLG RPLLIEDIRE ELDPALDNVL EKNFIKSGTA
3790 3800 3810 3820 3830 3840
FKVKVGDKEC DIMDTFKLYI TTKLPNPAFT PEINAKTSVI DFTVTMKGLE NQLLRRVILT
3850 3860 3870 3880 3890 3900
EKQELESERV KLLEDVTFNK RKMKELEDNL LYKLSATKGS LVDDESLIGV LRITKQTAAE
3910 3920 3930 3940 3950 3960
VSEKLHVAAE TEIKINTAQE EFRPAATRGS ILYFLITEMS MVNIMYQTSL AQFLKLFDQS
3970 3980 3990 4000 4010 4020
MARSEKSPLP QKRITNIIEY LTYEVFTYSV RGLYENHKFL FVLLMTLKID LQRGTVKHKE
4030 4040 4050 4060 4070 4080
FQALIKGGAA LDLKACPPKP FRWILDMTWL NLVELSKLPQ FAEIMNQISR NEKGWKNWFD
4090 4100 4110 4120 4130 4140
KDAPEEEIIP DGYNDSLDTC RKLLLIRSWC PDRTVFQARK YIADSLEEKY TEPVILNLEK
4150 4160 4170 4180 4190 4200
TWEESDTHTP LICFLSMGSD PTIQIDALAK KLKLECRTIS MGQGQEVHAR KLIQLSMQQG
4210 4220 4230 4240 4250 4260
GWVLLQNCHL GLEFMEELLE MLMVTETTED SFRVWITTEP HDRFPITLLQ TSIKFTNEPP
4270 4280 4290 4300 4310 4320
QGVRAGLKRT FAGINQDLLD ISNLPMWKPM LYTVAFLHST VQERRKFGPL GWNIPYEFNS
4330 4340 4350 4360 4370 4380
ADFSASVQFI QNHLDECDIK KGVSWSTVRY MIGEVQYGGR VTDDFDKRLL NCFARVWFSE
4390 4400 4410 4420 4430 4440
KMFEPSFCFY TGYKIPICKT LDQYFEFIQS LPSLDNPEVF GLHPNADITY QSNTASDVLE
4450 4460 4470 4480 4490 4500
TITNIQPKES GGGVGETREA IVYRLSEDML SKLPPNYVPH EVKARLMKMG HLNSMNIFLR
4510 4520 4530 4540 4550 4560
QEIDRMQKVI SILRSSLSDL KLAIEGTIIM SENLRDALDN MYDARIPQLW KRVSWDSSTL
4570 4580 4590 4600 4610 4620
GFWFTELLER NAQFSTWIFE GRPNVFWMTG FFNPQGFLTA MRQEVTRAHK GWALDTVTIH
4630 4640 4650 4660 4670 4680
NEVLRQTKEE IITPPAEGVY IYGLYMDGAS WDRRNGKLTE STPKVLFTQL PVLHIFAINS
4690 4700 4710 4720 4730
TAPKDPKLYV CPIYKKPRRT DLTFITVVYL RTVLSPDHWI LRGVALLCDI K
Protein Neighborhood
Domains & Features
2 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates
N-termini
| Name | Sequence | Position | Modification | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMID) |
|---|---|---|---|---|---|---|---|---|---|
| Q91XQ0-1-unknown | MESEEG... | 1 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
| Q91XQ0-1-unknown | MESEEG... | 1 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt73410 | |||
| Q91XQ0-3672-unknown | MLVDPP... | 3672 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt73411 | |||
| Q91XQ0-3672-unknown | MLVDPP... | 3672 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TNt106783 |
C-termini
| Name | Sequence | Position | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
|---|---|---|---|---|---|---|---|---|
| ...LCDIK | 4731 | inferred from electronic annotation | electronic annotation | UniProtKB | inferred from uniprot | |||
| ...LCDIK | 4731 | inferred from isoform by sequence similarity | unknown | TopFIND | inferred from TCt69029 |
Cleavages
| Protease | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
|---|
Substrates
| Substrate | Position | Sequence | Evidence type | Method | Source (database) | Source (Lab) | Evidence name | Publications (PMIDs) |
|---|