TopFIND 4.0

Q91ZW6: Trimethyllysine dioxygenase, mitochondrial

General Information

Protein names
- Trimethyllysine dioxygenase, mitochondrial
- 1.14.11.8 {ECO:0000269|PubMed:11431483}
- Epsilon-trimethyllysine 2-oxoglutarate dioxygenase
- TML hydroxylase
- TML-alpha-ketoglutarate dioxygenase
- TML dioxygenase
- TMLD
Gene names Tmlhe
Organism Rattus norvegicus
Protease Family
Protease ID
Chromosome location
UniProt ID Q91ZW6

2

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MWYHKLLHQQ SRLQNLMKRG DIAHGLRLSG FKSLFPFSLH WCHTASKSVN CTWHQHEDHL 
        70         80         90        100        110        120 
ELQYASTVMR FDYVWLRDHC RSASCYNSKT HQRSLDTASV DLCIKPKTIR LDESTLFFTW 
       130        140        150        160        170        180 
PDGHVTRYDL DWLVKNSYEG QKQEVIQPRV LWNAKLYQDA QLPSVDFQGF LETKEGLKKF 
       190        200        210        220        230        240 
LQNFLLYGIA FVENVPPTQE HTEKLARRVS LIRETIYGRM WYFTSDFSRG DTAYTKLALD 
       250        260        270        280        290        300 
RHTDTTYFQE PCGIQVFHCL KHEGTGGRTL LVDGFYAAQQ VLQRAPEEFD LLSQVPLKHE 
       310        320        330        340        350        360 
YIENVGQCHN HMIGVGPILN IYPWNKELYL IRYNNYDRAV INTVPYDVVR RWYAAHRTLT 
       370        380        390        400        410        420 
TELRRPENEL WVKLKPGKVL FIDNWRVLHG RESFTGYRQL CGCYLTRDDV LNTARILGLH 
   
A

Isoforms

- Isoform 2 of Trimethyllysine dioxygenase, mitochondrial

Sequence View

        10         20         30         40         50         60 
MWYHKLLHQQ SRLQNLMKRG DIAHGLRLSG FKSLFPFSLH WCHTASKSVN CTWHQHEDHL 
        70         80         90        100        110        120 
ELQYASTVMR FDYVWLRDHC RSASCYNSKT HQRSLDTASV DLCIKPKTIR LDESTLFFTW 
       130        140        150        160        170        180 
PDGHVTRYDL DWLVKNSYEG QKQEVIQPRV LWNAKLYQDA QLPSVDFQGF LETKEGLKKF 
       190        200        210        220        230        240 
LQNFLLYGIA FVENVPPTQE HTEKLARRVS LIRETIYGRM WYFTSDFSRG DTAYTKLALD 
       250        260        270        280        290        300 
RHTDTTYFQE PCGIQVFHCL KHEGTGGRTL LVDGFYAAQQ VLQRAPEEFD LLSQVPLKHE 
       310        320        330        340        350        360 
YIENVGQCHN HMIGVGPILN IYPWNKELYL IRYNNYDRAV INTVPYDVVR RWYAAHRTLT 
       370        380        390        400        410        420 
TELRRPENEL WVKLKPGKVL FIDNWRVLHG RESFTGYRQL CGCYLTRDDV LNTARILGLH 
   
A



Filter Information:


(REFRESH)

Directness:


Physiological Relevance:


Evidence Codes:


Methodology:


Perturbation of System:


Biological System:


Protease Assignment Confidence:


Evidence Names:


Database:


Lab:



Protein Neighborhood

Domains & Features

2 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    Q91ZW6-1-unknown MWYHKL... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt193624
    Q91ZW6-16-unknown LMKRGD... 16 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    Q91ZW6-16-unknown LMKRGD... 16 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt195063

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...LGLHA 421 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    ...LGLHA 421 inferred from isoform by sequence similarity unknown TopFIND inferred from TCt153570

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)