TopFIND 4.0

Q91ZX6: Sentrin-specific protease 2

General Information

Protein names
- Sentrin-specific protease 2
- 3.4.22.-
- Axam2
- SUMO-1 protease 1
- SuPr-1
- SUMO-1/Smt3-specific isopeptidase 2
- Smt3ip2
- Sentrin/SUMO-specific protease SENP2
Gene names Senp2
Organism Mus musculus
Protease Family
Protease ID C48.007
Chromosome location
UniProt ID Q91ZX6

2

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MYRWLAKVLG TILRLCERPA PGARALLKRR RSSSTLFSTA VDTDEIPAKR PRLDCFIHQV 
        70         80         90        100        110        120 
KNSLYNAASL FGFPFQLTTK PMVSSACNGT RNVAPSGEVF SNSSSCELMS SGSCSSMLKL 
       130        140        150        160        170        180 
GNKSPNGISD YPKIRVTVTR DQPRRVLPSF GFTLKSEGYN RRPSGRRHSK SNPESSLTWK 
       190        200        210        220        230        240 
PQEQGVTEMI SEEGGKGVRR PHCTVEEGVQ KDEREKYRKL LERLKEGAHG STFPPTVSHH 
       250        260        270        280        290        300 
SSQRIQMDTL KTKGWVEEQN HGVRTTHFVP KQYRVVETRG PLCSMRSEKR YSKGKADTEK 
       310        320        330        340        350        360 
VVGLRFEKEG TRGHQMEPDL SEEVSARLRL GSGSNGLLRR KISVLEIKEK NFPSKEKDRR 
       370        380        390        400        410        420 
TEDLFEFTED MEKEISNALG HGPPDEILSS AFKLRITRGD IQTLKNYHWL NDEVINFYMN 
       430        440        450        460        470        480 
LLVERSKKQG YPALHAFSTF FYPKLKSGGY QAVKRWTKGV NLFEQELVLV PIHRKVHWSL 
       490        500        510        520        530        540 
VVMDLRKKCL KYLDSMGQKG HRICEILLQY LQDESKTKRN TDLNLLEWTH YSMKPHEIPQ 
       550        560        570        580    
QLNGSDCGMF TCKYADYISR DKPITFTQHQ MPLFRKKMVW EILHQQLL

Isoforms

- Isoform 2 of Sentrin-specific protease 2 - Isoform 3 of Sentrin-specific protease 2

Sequence View

        10         20         30         40         50         60 
MYRWLAKVLG TILRLCERPA PGARALLKRR RSSSTLFSTA VDTDEIPAKR PRLDCFIHQV 
        70         80         90        100        110        120 
KNSLYNAASL FGFPFQLTTK PMVSSACNGT RNVAPSGEVF SNSSSCELMS SGSCSSMLKL 
       130        140        150        160        170        180 
GNKSPNGISD YPKIRVTVTR DQPRRVLPSF GFTLKSEGYN RRPSGRRHSK SNPESSLTWK 
       190        200        210        220        230        240 
PQEQGVTEMI SEEGGKGVRR PHCTVEEGVQ KDEREKYRKL LERLKEGAHG STFPPTVSHH 
       250        260        270        280        290        300 
SSQRIQMDTL KTKGWVEEQN HGVRTTHFVP KQYRVVETRG PLCSMRSEKR YSKGKADTEK 
       310        320        330        340        350        360 
VVGLRFEKEG TRGHQMEPDL SEEVSARLRL GSGSNGLLRR KISVLEIKEK NFPSKEKDRR 
       370        380        390        400        410        420 
TEDLFEFTED MEKEISNALG HGPPDEILSS AFKLRITRGD IQTLKNYHWL NDEVINFYMN 
       430        440        450        460        470        480 
LLVERSKKQG YPALHAFSTF FYPKLKSGGY QAVKRWTKGV NLFEQELVLV PIHRKVHWSL 
       490        500        510        520        530        540 
VVMDLRKKCL KYLDSMGQKG HRICEILLQY LQDESKTKRN TDLNLLEWTH YSMKPHEIPQ 
       550        560        570        580    
QLNGSDCGMF TCKYADYISR DKPITFTQHQ MPLFRKKMVW EILHQQLL         10         20         30         40         50         60 
MYRWLAKVLG TILRLCERPA PGARALLKRR RSSSTLFSTA VDTDEIPAKR PRLDCFIHQV 
        70         80         90        100        110        120 
KNSLYNAASL FGFPFQLTTK PMVSSACNGT RNVAPSGEVF SNSSSCELMS SGSCSSMLKL 
       130        140        150        160        170        180 
GNKSPNGISD YPKIRVTVTR DQPRRVLPSF GFTLKSEGYN RRPSGRRHSK SNPESSLTWK 
       190        200        210        220        230        240 
PQEQGVTEMI SEEGGKGVRR PHCTVEEGVQ KDEREKYRKL LERLKEGAHG STFPPTVSHH 
       250        260        270        280        290        300 
SSQRIQMDTL KTKGWVEEQN HGVRTTHFVP KQYRVVETRG PLCSMRSEKR YSKGKADTEK 
       310        320        330        340        350        360 
VVGLRFEKEG TRGHQMEPDL SEEVSARLRL GSGSNGLLRR KISVLEIKEK NFPSKEKDRR 
       370        380        390        400        410        420 
TEDLFEFTED MEKEISNALG HGPPDEILSS AFKLRITRGD IQTLKNYHWL NDEVINFYMN 
       430        440        450        460        470        480 
LLVERSKKQG YPALHAFSTF FYPKLKSGGY QAVKRWTKGV NLFEQELVLV PIHRKVHWSL 
       490        500        510        520        530        540 
VVMDLRKKCL KYLDSMGQKG HRICEILLQY LQDESKTKRN TDLNLLEWTH YSMKPHEIPQ 
       550        560        570        580    
QLNGSDCGMF TCKYADYISR DKPITFTQHQ MPLFRKKMVW EILHQQLL



Filter Information:


(REFRESH)

Directness:


Physiological Relevance:


Evidence Codes:


Methodology:


Perturbation of System:


Biological System:


Protease Assignment Confidence:


Evidence Names:


Database:


Lab:



Protein Neighborhood

Domains & Features

2 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    Q91ZX6-1-unknown MYRWLA... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    Q91ZX6-82-unknown MVSSAC... 82 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt89257
    Q91ZX6-82-unknown MVSSAC... 82 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt105333

C-termini

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)