TopFIND 4.0

Q92187: CMP-N-acetylneuraminate-poly-alpha-2,8-sialyltransferase

General Information

Protein names
- CMP-N-acetylneuraminate-poly-alpha-2,8-sialyltransferase
- 2.4.99.-
- Alpha-2,8-sialyltransferase 8D
- Polysialyltransferase-1
- Sialyltransferase 8D
- SIAT8-D
- Sialyltransferase St8Sia IV
- ST8SiaIV
Gene names ST8SIA4
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID Q92187

1

N-termini

2

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MRSIRKRWTI CTISLLLIFY KTKEIARTEE HQETQLIGDG ELSLSRSLVN SSDKIIRKAG 
        70         80         90        100        110        120 
SSIFQHNVEG WKINSSLVLE IRKNILRFLD AERDVSVVKS SFKPGDVIHY VLDRRRTLNI 
       130        140        150        160        170        180 
SHDLHSLLPE VSPMKNRRFK TCAVVGNSGI LLDSECGKEI DSHNFVIRCN LAPVVEFAAD 
       190        200        210        220        230        240 
VGTKSDFITM NPSVVQRAFG GFRNESDREK FVHRLSMLND SVLWIPAFMV KGGEKHVEWV 
       250        260        270        280        290        300 
NALILKNKLK VRTAYPSLRL IHAVRGYWLT NKVPIKRPST GLLMYTLATR FCDEIHLYGF 
       310        320        330        340        350    
WPFPKDLNGK AVKYHYYDDL KYRYFSNASP HRMPLEFKTL NVLHNRGALK LTTGKCVKQ

Isoforms

- Isoform 2 of CMP-N-acetylneuraminate-poly-alpha-2,8-sialyltransferase

Sequence View

        10         20         30         40         50         60 
MRSIRKRWTI CTISLLLIFY KTKEIARTEE HQETQLIGDG ELSLSRSLVN SSDKIIRKAG 
        70         80         90        100        110        120 
SSIFQHNVEG WKINSSLVLE IRKNILRFLD AERDVSVVKS SFKPGDVIHY VLDRRRTLNI 
       130        140        150        160        170        180 
SHDLHSLLPE VSPMKNRRFK TCAVVGNSGI LLDSECGKEI DSHNFVIRCN LAPVVEFAAD 
       190        200        210        220        230        240 
VGTKSDFITM NPSVVQRAFG GFRNESDREK FVHRLSMLND SVLWIPAFMV KGGEKHVEWV 
       250        260        270        280        290        300 
NALILKNKLK VRTAYPSLRL IHAVRGYWLT NKVPIKRPST GLLMYTLATR FCDEIHLYGF 
       310        320        330        340        350    
WPFPKDLNGK AVKYHYYDDL KYRYFSNASP HRMPLEFKTL NVLHNRGALK LTTGKCVKQ



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Directness:


Physiological Relevance:


Evidence Codes:


Methodology:


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Biological System:


Protease Assignment Confidence:


Evidence Names:


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Protein Neighborhood

Domains & Features

1 N-termini - 2 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    Q92187-1-unknown MRSIRK... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    Q92187-1-unknown MRSIRK... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt89690

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...NFVIRC 168 inferred from isoform by sequence similarity unknown TopFIND inferred from TCt85308
    ...KCVKQ 359 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)