TopFIND 4.0

Q92484: Acid sphingomyelinase-like phosphodiesterase 3a

General Information

Protein names
- Acid sphingomyelinase-like phosphodiesterase 3a
- ASM-like phosphodiesterase 3a
- 3.1.4.- {ECO:0000269|PubMed:25288789, ECO:0000269|PubMed:26783088}
Gene names SMPDL3A
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID Q92484

2

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MALVRALVCC LLTAWHCRSG LGLPVAPAGG RNPPPAIGQF WHVTDLHLDP TYHITDDHTK 
        70         80         90        100        110        120 
VCASSKGANA SNPGPFGDVL CDSPYQLILS AFDFIKNSGQ EASFMIWTGD SPPHVPVPEL 
       130        140        150        160        170        180 
STDTVINVIT NMTTTIQSLF PNLQVFPALG NHDYWPQDQL PVVTSKVYNA VANLWKPWLD 
       190        200        210        220        230        240 
EEAISTLRKG GFYSQKVTTN PNLRIISLNT NLYYGPNIMT LNKTDPANQF EWLESTLNNS 
       250        260        270        280        290        300 
QQNKEKVYII AHVPVGYLPS SQNITAMREY YNEKLIDIFQ KYSDVIAGQF YGHTHRDSIM 
       310        320        330        340        350        360 
VLSDKKGSPV NSLFVAPAVT PVKSVLEKQT NNPGIRLFQY DPRDYKLLDM LQYYLNLTEA 
       370        380        390        400        410        420 
NLKGESIWKL EYILTQTYDI EDLQPESLYG LAKQFTILDS KQFIKYYNYF FVSYDSSVTC 
       430        440        450    
DKTCKAFQIC AIMNLDNISY ADCLKQLYIK HNY

Isoforms

- Isoform 2 of Acid sphingomyelinase-like phosphodiesterase 3a

Sequence View

        10         20         30         40         50         60 
MALVRALVCC LLTAWHCRSG LGLPVAPAGG RNPPPAIGQF WHVTDLHLDP TYHITDDHTK 
        70         80         90        100        110        120 
VCASSKGANA SNPGPFGDVL CDSPYQLILS AFDFIKNSGQ EASFMIWTGD SPPHVPVPEL 
       130        140        150        160        170        180 
STDTVINVIT NMTTTIQSLF PNLQVFPALG NHDYWPQDQL PVVTSKVYNA VANLWKPWLD 
       190        200        210        220        230        240 
EEAISTLRKG GFYSQKVTTN PNLRIISLNT NLYYGPNIMT LNKTDPANQF EWLESTLNNS 
       250        260        270        280        290        300 
QQNKEKVYII AHVPVGYLPS SQNITAMREY YNEKLIDIFQ KYSDVIAGQF YGHTHRDSIM 
       310        320        330        340        350        360 
VLSDKKGSPV NSLFVAPAVT PVKSVLEKQT NNPGIRLFQY DPRDYKLLDM LQYYLNLTEA 
       370        380        390        400        410        420 
NLKGESIWKL EYILTQTYDI EDLQPESLYG LAKQFTILDS KQFIKYYNYF FVSYDSSVTC 
       430        440        450    
DKTCKAFQIC AIMNLDNISY ADCLKQLYIK HNY



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Protein Neighborhood

Domains & Features

2 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...IKHNY 453 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    ...IKHNY 453 inferred from isoform by sequence similarity unknown TopFIND inferred from TCt63268

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)