Q924A0: Transcription factor 7-like 2

General Information

Protein names	- Transcription factor 7-like 2 - HMG box transcription factor 4 - T-cell-specific transcription factor 4 - T-cell factor 4 - TCF-4 - mTCF-4
Gene names	Tcf7l2
Organism	Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID	Q924A0

1 N-termini

4 C-termini

0 Cleavages

0 Substrates

Sequence

Isoforms

- Isoform 2 of Transcription factor 7-like 2 - Isoform 3 of Transcription factor 7-like 2 - Isoform 4 of Transcription factor 7-like 2 - Isoform 5 of Transcription factor 7-like 2 - Isoform 6 of Transcription factor 7-like 2 - Isoform 7 of Transcription factor 7-like 2 - Isoform 8 of Transcription factor 7-like 2 - Isoform 9 of Transcription factor 7-like 2

Sequence View

        10         20         30         40         50         60
MPQLNGGGGD DLGANDELIS FKDEGEQEEK NSENSSAERD LADVKSSLVN ESETNQDSSS
        70         80         90        100        110        120
DSEAERRPPP RSESFRDKSR ESLEEAAKRQ DGGLFKGPPY PGYPFIMIPD LTSPYLPNGS
       130        140        150        160        170        180
LSPTARTYLQ MKWPLLDVQA GSLQSRQTLK DARSPSPAHI VSNKVPVVQH PHHVHPLTPL
       190        200        210        220        230        240
ITYSNEHFTP GNPPPHLPAD VDPKTGIPRP PHPPDISPYY PLSPGTVGQI PHPLGWLVPQ
       250        260        270        280        290        300
QGQPVYPITT GGFRHPYPTA LTVNASMSRF PPHMVPPHHT LHTTGIPHPA IVTPTVKQES
       310        320        330        340        350        360
SQSDVGSLHS SKHQDSKKEE EKKKPHIKKP LNAFMLYMKE MRAKVVAECT LKESAAINQI
       370        380        390        400        410        420
LGRRWHALSR EEQAKYYELA RKERQLHMQL YPGWSARDNY GKKKKRKRDK QPGETNEHSE
       430        440        450
CFLNPCLSLP PITDLSAPKK CRARFGLDQQ NNWCGPCSL         10         20         30         40         50         60
MPQLNGGGGD DLGANDELIS FKDEGEQEEK NSENSSAERD LADVKSSLVN ESETNQDSSS
        70         80         90        100        110        120
DSEAERRPPP RSESFRDKSR ESLEEAAKRQ DGGLFKGPPY PGYPFIMIPD LTSPYLPNGS
       130        140        150        160        170        180
LSPTARTYLQ MKWPLLDVQA GSLQSRQTLK DARSPSPAHI VSNKVPVVQH PHHVHPLTPL
       190        200        210        220        230        240
ITYSNEHFTP GNPPPHLPAD VDPKTGIPRP PHPPDISPYY PLSPGTVGQI PHPLGWLVPQ
       250        260        270        280        290        300
QGQPVYPITT GGFRHPYPTA LTVNASMSRF PPHMVPPHHT LHTTGIPHPA IVTPTVKQES
       310        320        330        340        350        360
SQSDVGSLHS SKHQDSKKEE EKKKPHIKKP LNAFMLYMKE MRAKVVAECT LKESAAINQI
       370        380        390        400        410        420
LGRRWHALSR EEQAKYYELA RKERQLHMQL YPGWSARDNY GKKKKRKRDK QPGETNEHSE
       430        440        450
CFLNPCLSLP PITDLSAPKK CRARFGLDQQ NNWCGPCSL         10         20         30         40         50         60
MPQLNGGGGD DLGANDELIS FKDEGEQEEK NSENSSAERD LADVKSSLVN ESETNQDSSS
        70         80         90        100        110        120
DSEAERRPPP RSESFRDKSR ESLEEAAKRQ DGGLFKGPPY PGYPFIMIPD LTSPYLPNGS
       130        140        150        160        170        180
LSPTARTYLQ MKWPLLDVQA GSLQSRQTLK DARSPSPAHI VSNKVPVVQH PHHVHPLTPL
       190        200        210        220        230        240
ITYSNEHFTP GNPPPHLPAD VDPKTGIPRP PHPPDISPYY PLSPGTVGQI PHPLGWLVPQ
       250        260        270        280        290        300
QGQPVYPITT GGFRHPYPTA LTVNASMSRF PPHMVPPHHT LHTTGIPHPA IVTPTVKQES
       310        320        330        340        350        360
SQSDVGSLHS SKHQDSKKEE EKKKPHIKKP LNAFMLYMKE MRAKVVAECT LKESAAINQI
       370        380        390        400        410        420
LGRRWHALSR EEQAKYYELA RKERQLHMQL YPGWSARDNY GKKKKRKRDK QPGETNEHSE
       430        440        450
CFLNPCLSLP PITDLSAPKK CRARFGLDQQ NNWCGPCSL         10         20         30         40         50         60
MPQLNGGGGD DLGANDELIS FKDEGEQEEK NSENSSAERD LADVKSSLVN ESETNQDSSS
        70         80         90        100        110        120
DSEAERRPPP RSESFRDKSR ESLEEAAKRQ DGGLFKGPPY PGYPFIMIPD LTSPYLPNGS
       130        140        150        160        170        180
LSPTARTYLQ MKWPLLDVQA GSLQSRQTLK DARSPSPAHI VSNKVPVVQH PHHVHPLTPL
       190        200        210        220        230        240
ITYSNEHFTP GNPPPHLPAD VDPKTGIPRP PHPPDISPYY PLSPGTVGQI PHPLGWLVPQ
       250        260        270        280        290        300
QGQPVYPITT GGFRHPYPTA LTVNASMSRF PPHMVPPHHT LHTTGIPHPA IVTPTVKQES
       310        320        330        340        350        360
SQSDVGSLHS SKHQDSKKEE EKKKPHIKKP LNAFMLYMKE MRAKVVAECT LKESAAINQI
       370        380        390        400        410        420
LGRRWHALSR EEQAKYYELA RKERQLHMQL YPGWSARDNY GKKKKRKRDK QPGETNEHSE
       430        440        450
CFLNPCLSLP PITDLSAPKK CRARFGLDQQ NNWCGPCSL         10         20         30         40         50         60
MPQLNGGGGD DLGANDELIS FKDEGEQEEK NSENSSAERD LADVKSSLVN ESETNQDSSS
        70         80         90        100        110        120
DSEAERRPPP RSESFRDKSR ESLEEAAKRQ DGGLFKGPPY PGYPFIMIPD LTSPYLPNGS
       130        140        150        160        170        180
LSPTARTYLQ MKWPLLDVQA GSLQSRQTLK DARSPSPAHI VSNKVPVVQH PHHVHPLTPL
       190        200        210        220        230        240
ITYSNEHFTP GNPPPHLPAD VDPKTGIPRP PHPPDISPYY PLSPGTVGQI PHPLGWLVPQ
       250        260        270        280        290        300
QGQPVYPITT GGFRHPYPTA LTVNASMSRF PPHMVPPHHT LHTTGIPHPA IVTPTVKQES
       310        320        330        340        350        360
SQSDVGSLHS SKHQDSKKEE EKKKPHIKKP LNAFMLYMKE MRAKVVAECT LKESAAINQI
       370        380        390        400        410        420
LGRRWHALSR EEQAKYYELA RKERQLHMQL YPGWSARDNY GKKKKRKRDK QPGETNEHSE
       430        440        450
CFLNPCLSLP PITDLSAPKK CRARFGLDQQ NNWCGPCSL         10         20         30         40         50         60
MPQLNGGGGD DLGANDELIS FKDEGEQEEK NSENSSAERD LADVKSSLVN ESETNQDSSS
        70         80         90        100        110        120
DSEAERRPPP RSESFRDKSR ESLEEAAKRQ DGGLFKGPPY PGYPFIMIPD LTSPYLPNGS
       130        140        150        160        170        180
LSPTARTYLQ MKWPLLDVQA GSLQSRQTLK DARSPSPAHI VSNKVPVVQH PHHVHPLTPL
       190        200        210        220        230        240
ITYSNEHFTP GNPPPHLPAD VDPKTGIPRP PHPPDISPYY PLSPGTVGQI PHPLGWLVPQ
       250        260        270        280        290        300
QGQPVYPITT GGFRHPYPTA LTVNASMSRF PPHMVPPHHT LHTTGIPHPA IVTPTVKQES
       310        320        330        340        350        360
SQSDVGSLHS SKHQDSKKEE EKKKPHIKKP LNAFMLYMKE MRAKVVAECT LKESAAINQI
       370        380        390        400        410        420
LGRRWHALSR EEQAKYYELA RKERQLHMQL YPGWSARDNY GKKKKRKRDK QPGETNEHSE
       430        440        450
CFLNPCLSLP PITDLSAPKK CRARFGLDQQ NNWCGPCSL         10         20         30         40         50         60
MPQLNGGGGD DLGANDELIS FKDEGEQEEK NSENSSAERD LADVKSSLVN ESETNQDSSS
        70         80         90        100        110        120
DSEAERRPPP RSESFRDKSR ESLEEAAKRQ DGGLFKGPPY PGYPFIMIPD LTSPYLPNGS
       130        140        150        160        170        180
LSPTARTYLQ MKWPLLDVQA GSLQSRQTLK DARSPSPAHI VSNKVPVVQH PHHVHPLTPL
       190        200        210        220        230        240
ITYSNEHFTP GNPPPHLPAD VDPKTGIPRP PHPPDISPYY PLSPGTVGQI PHPLGWLVPQ
       250        260        270        280        290        300
QGQPVYPITT GGFRHPYPTA LTVNASMSRF PPHMVPPHHT LHTTGIPHPA IVTPTVKQES
       310        320        330        340        350        360
SQSDVGSLHS SKHQDSKKEE EKKKPHIKKP LNAFMLYMKE MRAKVVAECT LKESAAINQI
       370        380        390        400        410        420
LGRRWHALSR EEQAKYYELA RKERQLHMQL YPGWSARDNY GKKKKRKRDK QPGETNEHSE
       430        440        450
CFLNPCLSLP PITDLSAPKK CRARFGLDQQ NNWCGPCSL         10         20         30         40         50         60
MPQLNGGGGD DLGANDELIS FKDEGEQEEK NSENSSAERD LADVKSSLVN ESETNQDSSS
        70         80         90        100        110        120
DSEAERRPPP RSESFRDKSR ESLEEAAKRQ DGGLFKGPPY PGYPFIMIPD LTSPYLPNGS
       130        140        150        160        170        180
LSPTARTYLQ MKWPLLDVQA GSLQSRQTLK DARSPSPAHI VSNKVPVVQH PHHVHPLTPL
       190        200        210        220        230        240
ITYSNEHFTP GNPPPHLPAD VDPKTGIPRP PHPPDISPYY PLSPGTVGQI PHPLGWLVPQ
       250        260        270        280        290        300
QGQPVYPITT GGFRHPYPTA LTVNASMSRF PPHMVPPHHT LHTTGIPHPA IVTPTVKQES
       310        320        330        340        350        360
SQSDVGSLHS SKHQDSKKEE EKKKPHIKKP LNAFMLYMKE MRAKVVAECT LKESAAINQI
       370        380        390        400        410        420
LGRRWHALSR EEQAKYYELA RKERQLHMQL YPGWSARDNY GKKKKRKRDK QPGETNEHSE
       430        440        450
CFLNPCLSLP PITDLSAPKK CRARFGLDQQ NNWCGPCSL

Filter Information:

(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

1 N-termini - 4 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Evidence name
Q924A0-1-unknown	MPQLNG...	1	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
Q924A0-1-unknown	MPQLNG...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt91965
Q924A0-1-unknown	MPQLNG...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt91966
Q924A0-1-unknown	MPQLNG...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt91967
Q924A0-1-unknown	MPQLNG...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt91968
Q924A0-1-unknown	MPQLNG...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt91969
Q924A0-1-unknown	MPQLNG...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt91970
Q924A0-1-unknown	MPQLNG...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt91971

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...ASMSRF	269	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt87587
...ASMSRF	269	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt87588
...ASMSRF	269	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt87586
...ASMSRF	269	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSMUSP00000107279
...ASMSRF	269	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSMUSP00000107276
...ASMSRF	269	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSMUSP00000107278
...ASMSRF	269	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt92169
...ASMSRF	269	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt92171
...ASMSRF	269	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt92170
...FMLYMK	338	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSMUSP00000118042
...YPGWSA	395	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSMUSP00000119759
...GPCSL	459	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...GPCSL	459	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt87590
...GPCSL	459	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt87584

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)