Q92558: Wiskott-Aldrich syndrome protein family member 1

General Information

Protein names	- Wiskott-Aldrich syndrome protein family member 1 - WASP family protein member 1 - Protein WAVE-1 - Verprolin homology domain-containing protein 1
Gene names	WASF1
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q92558

2 N-termini

4 C-termini

0 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MPLVKRNIDP RHLCHTALPR GIKNELECVT NISLANIIRQ LSSLSKYAED IFGELFNEAH
        70         80         90        100        110        120
SFSFRVNSLQ ERVDRLSVSV TQLDPKEEEL SLQDITMRKA FRSSTIQDQQ LFDRKTLPIP
       130        140        150        160        170        180
LQETYDVCEQ PPPLNILTPY RDDGKEGLKF YTNPSYFFDL WKEKMLQDTE DKRKEKRKQK
       190        200        210        220        230        240
QKNLDRPHEP EKVPRAPHDR RREWQKLAQG PELAEDDANL LHKHIEVANG PASHFETRPQ
       250        260        270        280        290        300
TYVDHMDGSY SLSALPFSQM SELLTRAEER VLVRPHEPPP PPPMHGAGDA KPIPTCISSA
       310        320        330        340        350        360
TGLIENRPQS PATGRTPVFV SPTPPPPPPP LPSALSTSSL RASMTSTPPP PVPPPPPPPA
       370        380        390        400        410        420
TALQAPAVPP PPAPLQIAPG VLHPAPPPIA PPLVQPSPPV ARAAPVCETV PVHPLPQGEV
       430        440        450        460        470        480
QGLPPPPPPP PLPPPGIRPS SPVTVTALAH PPSGLHPTPS TAPGPHVPLM PPSPPSQVIP
       490        500        510        520        530        540
ASEPKRHPST LPVISDARSV LLEAIRKGIQ LRKVEEQREQ EAKHERIEND VATILSRRIA
       550
VEYSDSEDDS EFDEVDWLE

Isoforms

Sequence View

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Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

2 N-termini - 4 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
Q92558-1-unknown	MPLVKR...	1	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q92558-254-	ALPFSQ...	254		Subtiligase Based Positive Selection		Wells	DB_Untreated	23264352
Q92558-254-	ALPFSQ...	254		Subtiligase Based Positive Selection		Wells	apoptotic_Jurkat_bortezomib	23264352

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...PKEEEL	89	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000402663
...PKEEEL	89	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000404142
...ILTPYR	140	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000265601
...ILTPYR	140	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000357934
...KRKQKQ	180	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000407041
...VDWLE	559	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)