TopFIND 4.0

Q925Q3: Mitochondrial sodium/calcium exchanger protein {ECO:0000305}

General Information

Protein names
- Mitochondrial sodium/calcium exchanger protein {ECO:0000305}
- Na(+)/K(+)/Ca(2+)-exchange protein 6 {ECO:0000303|PubMed:14625281}
- Sodium/calcium exchanger protein, mitochondrial {ECO:0000303|PubMed:20018762}
- Sodium/potassium/calcium exchanger 6 {ECO:0000303|PubMed:14625281}
- Solute carrier family 24 member 6 {ECO:0000312|MGI:MGI:2180781}
- Solute carrier family 8 member B1 {ECO:0000312|MGI:MGI:2180781}
Gene names Slc8b1
Organism Mus musculus
Protease Family
Protease ID
Chromosome location
UniProt ID Q925Q3

2

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MASRWLALLW APVFLCVALI LETASGTGDP STKAHGHIQF SAGSVNQTAM ADCRAVCGLN 
        70         80         90        100        110        120 
TSDRCDFVRR NPDCRSEAGY LDYLEGIFCY FPPNLLPLAI TLYVFWLLYL FLILGVTAAK 
       130        140        150        160        170        180 
FFCPNLSAIS TNLKLSHNVA GVTFLAFGNG APDIFSALVA FSDPRTAGLA IGALFGAGVL 
       190        200        210        220        230        240 
VTTVVAGGIT ILHPFMAASR PFLRDIAFYM VAVFLTFTAL YLGRITLTWA LGYLGLYVFY 
       250        260        270        280        290        300 
VVTVIICTWV YQRQRSRSLV HSISETPELL SESEEDQMSS NTNSYDYGDE YRPLLLGRET 
       310        320        330        340        350        360 
TVQILIQALN PLDYRKWRTQ SISWRVLKVV KLPVEFLLLL TVPVVDPDKD DRNWKRPLNC 
       370        380        390        400        410        420 
LQLVISPLVL VLTLQSGVYG IYEIGGLLPV WAVVVIVGTA LASVTFFATS NREPPRLHWL 
       430        440        450        460        470        480 
FAFLGFLTSA LWINAAATEV VNILRSLGVI FRLSNTVLGL TLLAWGNSIG DAFSDFTLAR 
       490        500        510        520        530        540 
QGYPRMAFSA CFGGIIFNIL VGVGLGCLLQ IIRNHVVEVK LEPDGLLVWV LASALGLSLI 
       550        560        570        580    
FSLVSVPLQC FQLSKAYGLC LLLFYICFLV VVLLTEFGVI HLKKA

Isoforms

- Isoform 2 of Sodium/potassium/calcium exchanger 6, mitochondrial - Isoform 3 of Sodium/potassium/calcium exchanger 6, mitochondrial - Isoform 2 of Mitochondrial sodium/calcium exchanger protein - Isoform 3 of Mitochondrial sodium/calcium exchanger protein

Sequence View

        10         20         30         40         50         60 
MASRWLALLW APVFLCVALI LETASGTGDP STKAHGHIQF SAGSVNQTAM ADCRAVCGLN 
        70         80         90        100        110        120 
TSDRCDFVRR NPDCRSEAGY LDYLEGIFCY FPPNLLPLAI TLYVFWLLYL FLILGVTAAK 
       130        140        150        160        170        180 
FFCPNLSAIS TNLKLSHNVA GVTFLAFGNG APDIFSALVA FSDPRTAGLA IGALFGAGVL 
       190        200        210        220        230        240 
VTTVVAGGIT ILHPFMAASR PFLRDIAFYM VAVFLTFTAL YLGRITLTWA LGYLGLYVFY 
       250        260        270        280        290        300 
VVTVIICTWV YQRQRSRSLV HSISETPELL SESEEDQMSS NTNSYDYGDE YRPLLLGRET 
       310        320        330        340        350        360 
TVQILIQALN PLDYRKWRTQ SISWRVLKVV KLPVEFLLLL TVPVVDPDKD DRNWKRPLNC 
       370        380        390        400        410        420 
LQLVISPLVL VLTLQSGVYG IYEIGGLLPV WAVVVIVGTA LASVTFFATS NREPPRLHWL 
       430        440        450        460        470        480 
FAFLGFLTSA LWINAAATEV VNILRSLGVI FRLSNTVLGL TLLAWGNSIG DAFSDFTLAR 
       490        500        510        520        530        540 
QGYPRMAFSA CFGGIIFNIL VGVGLGCLLQ IIRNHVVEVK LEPDGLLVWV LASALGLSLI 
       550        560        570        580    
FSLVSVPLQC FQLSKAYGLC LLLFYICFLV VVLLTEFGVI HLKKA         10         20         30         40         50         60 
MASRWLALLW APVFLCVALI LETASGTGDP STKAHGHIQF SAGSVNQTAM ADCRAVCGLN 
        70         80         90        100        110        120 
TSDRCDFVRR NPDCRSEAGY LDYLEGIFCY FPPNLLPLAI TLYVFWLLYL FLILGVTAAK 
       130        140        150        160        170        180 
FFCPNLSAIS TNLKLSHNVA GVTFLAFGNG APDIFSALVA FSDPRTAGLA IGALFGAGVL 
       190        200        210        220        230        240 
VTTVVAGGIT ILHPFMAASR PFLRDIAFYM VAVFLTFTAL YLGRITLTWA LGYLGLYVFY 
       250        260        270        280        290        300 
VVTVIICTWV YQRQRSRSLV HSISETPELL SESEEDQMSS NTNSYDYGDE YRPLLLGRET 
       310        320        330        340        350        360 
TVQILIQALN PLDYRKWRTQ SISWRVLKVV KLPVEFLLLL TVPVVDPDKD DRNWKRPLNC 
       370        380        390        400        410        420 
LQLVISPLVL VLTLQSGVYG IYEIGGLLPV WAVVVIVGTA LASVTFFATS NREPPRLHWL 
       430        440        450        460        470        480 
FAFLGFLTSA LWINAAATEV VNILRSLGVI FRLSNTVLGL TLLAWGNSIG DAFSDFTLAR 
       490        500        510        520        530        540 
QGYPRMAFSA CFGGIIFNIL VGVGLGCLLQ IIRNHVVEVK LEPDGLLVWV LASALGLSLI 
       550        560        570        580    
FSLVSVPLQC FQLSKAYGLC LLLFYICFLV VVLLTEFGVI HLKKA         10         20         30         40         50         60 
MASRWLALLW APVFLCVALI LETASGTGDP STKAHGHIQF SAGSVNQTAM ADCRAVCGLN 
        70         80         90        100        110        120 
TSDRCDFVRR NPDCRSEAGY LDYLEGIFCY FPPNLLPLAI TLYVFWLLYL FLILGVTAAK 
       130        140        150        160        170        180 
FFCPNLSAIS TNLKLSHNVA GVTFLAFGNG APDIFSALVA FSDPRTAGLA IGALFGAGVL 
       190        200        210        220        230        240 
VTTVVAGGIT ILHPFMAASR PFLRDIAFYM VAVFLTFTAL YLGRITLTWA LGYLGLYVFY 
       250        260        270        280        290        300 
VVTVIICTWV YQRQRSRSLV HSISETPELL SESEEDQMSS NTNSYDYGDE YRPLLLGRET 
       310        320        330        340        350        360 
TVQILIQALN PLDYRKWRTQ SISWRVLKVV KLPVEFLLLL TVPVVDPDKD DRNWKRPLNC 
       370        380        390        400        410        420 
LQLVISPLVL VLTLQSGVYG IYEIGGLLPV WAVVVIVGTA LASVTFFATS NREPPRLHWL 
       430        440        450        460        470        480 
FAFLGFLTSA LWINAAATEV VNILRSLGVI FRLSNTVLGL TLLAWGNSIG DAFSDFTLAR 
       490        500        510        520        530        540 
QGYPRMAFSA CFGGIIFNIL VGVGLGCLLQ IIRNHVVEVK LEPDGLLVWV LASALGLSLI 
       550        560        570        580    
FSLVSVPLQC FQLSKAYGLC LLLFYICFLV VVLLTEFGVI HLKKA         10         20         30         40         50         60 
MASRWLALLW APVFLCVALI LETASGTGDP STKAHGHIQF SAGSVNQTAM ADCRAVCGLN 
        70         80         90        100        110        120 
TSDRCDFVRR NPDCRSEAGY LDYLEGIFCY FPPNLLPLAI TLYVFWLLYL FLILGVTAAK 
       130        140        150        160        170        180 
FFCPNLSAIS TNLKLSHNVA GVTFLAFGNG APDIFSALVA FSDPRTAGLA IGALFGAGVL 
       190        200        210        220        230        240 
VTTVVAGGIT ILHPFMAASR PFLRDIAFYM VAVFLTFTAL YLGRITLTWA LGYLGLYVFY 
       250        260        270        280        290        300 
VVTVIICTWV YQRQRSRSLV HSISETPELL SESEEDQMSS NTNSYDYGDE YRPLLLGRET 
       310        320        330        340        350        360 
TVQILIQALN PLDYRKWRTQ SISWRVLKVV KLPVEFLLLL TVPVVDPDKD DRNWKRPLNC 
       370        380        390        400        410        420 
LQLVISPLVL VLTLQSGVYG IYEIGGLLPV WAVVVIVGTA LASVTFFATS NREPPRLHWL 
       430        440        450        460        470        480 
FAFLGFLTSA LWINAAATEV VNILRSLGVI FRLSNTVLGL TLLAWGNSIG DAFSDFTLAR 
       490        500        510        520        530        540 
QGYPRMAFSA CFGGIIFNIL VGVGLGCLLQ IIRNHVVEVK LEPDGLLVWV LASALGLSLI 
       550        560        570        580    
FSLVSVPLQC FQLSKAYGLC LLLFYICFLV VVLLTEFGVI HLKKA



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Evidence Names:


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Protein Neighborhood

Domains & Features

2 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...HLKKA 585 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    ...HLKKA 585 inferred from isoform by sequence similarity unknown TopFIND inferred from TCt78019

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)