TopFIND 4.0

Q92743: Serine protease HTRA1

General Information

Protein names
- Serine protease HTRA1
- 3.4.21.-
- High-temperature requirement A serine peptidase 1
- L56
- Serine protease 11
Gene names HTRA1
Organism Homo sapiens
Protease Family S01.277
Protease ID S01.277
Chromosome location
UniProt ID Q92743

3

N-termini

1

C-termini

0

Cleavages

43

Substrates

Sequence

        10         20         30         40         50         60 
MQIPRAALLP LLLLLLAAPA SAQLSRAGRS APLAAGCPDR CEPARCPPQP EHCEGGRARD 
        70         80         90        100        110        120 
ACGCCEVCGA PEGAACGLQE GPCGEGLQCV VPFGVPASAT VRRRAQAGLC VCASSEPVCG 
       130        140        150        160        170        180 
SDANTYANLC QLRAASRRSE RLHRPPVIVL QRGACGQGQE DPNSLRHKYN FIADVVEKIA 
       190        200        210        220        230        240 
PAVVHIELFR KLPFSKREVP VASGSGFIVS EDGLIVTNAH VVTNKHRVKV ELKNGATYEA 
       250        260        270        280        290        300 
KIKDVDEKAD IALIKIDHQG KLPVLLLGRS SELRPGEFVV AIGSPFSLQN TVTTGIVSTT 
       310        320        330        340        350        360 
QRGGKELGLR NSDMDYIQTD AIINYGNSGG PLVNLDGEVI GINTLKVTAG ISFAIPSDKI 
       370        380        390        400        410        420 
KKFLTESHDR QAKGKAITKK KYIGIRMMSL TSSKAKELKD RHRDFPDVIS GAYIIEVIPD 
       430        440        450        460        470        480 
TPAEAGGLKE NDVIISINGQ SVVSANDVSD VIKRESTLNM VVRRGNEDIM ITVIPEEIDP 
   

Isoforms



Sequence View



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(REFRESH)

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Protein Neighborhood

Domains & Features

3 N-termini - 1 C-termini - 0 Cleavages - 43 Substrates

N-termini

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...EEIDP 480 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates