TopFIND 4.0

Q92952: Small conductance calcium-activated potassium channel protein 1

General Information

Protein names
- Small conductance calcium-activated potassium channel protein 1
- SK1
- SKCa 1
- SKCa1
- KCa2.1
Gene names KCNN1
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID Q92952

1

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MNSHSYNGSV GRPLGSGPGA LGRDPPDPEA GHPPQPPHSP GLQVVVAKSE PARPSPGSPR 
        70         80         90        100        110        120 
GQPQDQDDDE DDEEDEAGRQ RASGKPSNVG HRLGHRRALF EKRKRLSDYA LIFGMFGIVV 
       130        140        150        160        170        180 
MVTETELSWG VYTKESLYSF ALKCLISLST AILLGLVVLY HAREIQLFMV DNGADDWRIA 
       190        200        210        220        230        240 
MTCERVFLIS LELAVCAIHP VPGHYRFTWT ARLAFTYAPS VAEADVDVLL SIPMFLRLYL 
       250        260        270        280        290        300 
LGRVMLLHSK IFTDASSRSI GALNKITFNT RFVMKTLMTI CPGTVLLVFS ISSWIIAAWT 
       310        320        330        340        350        360 
VRVCERYHDK QEVTSNFLGA MWLISITFLS IGYGDMVPHT YCGKGVCLLT GIMGAGCTAL 
       370        380        390        400        410        420 
VVAVVARKLE LTKAEKHVHN FMMDTQLTKR VKNAAANVLR ETWLIYKHTR LVKKPDQARV 
       430        440        450        460        470        480 
RKHQRKFLQA IHQAQKLRSV KIEQGKLNDQ ANTLTDLAKT QTVMYDLVSE LHAQHEELEA 
       490        500        510        520        530        540 
RLATLESRLD ALGASLQALP GLIAQAIRPP PPPLPPRPGP GPQDQAARSS PCRWTPVAPS 
   
DCG

Isoforms

- Isoform 2 of Small conductance calcium-activated potassium channel protein 1

Sequence View

        10         20         30         40         50         60 
MNSHSYNGSV GRPLGSGPGA LGRDPPDPEA GHPPQPPHSP GLQVVVAKSE PARPSPGSPR 
        70         80         90        100        110        120 
GQPQDQDDDE DDEEDEAGRQ RASGKPSNVG HRLGHRRALF EKRKRLSDYA LIFGMFGIVV 
       130        140        150        160        170        180 
MVTETELSWG VYTKESLYSF ALKCLISLST AILLGLVVLY HAREIQLFMV DNGADDWRIA 
       190        200        210        220        230        240 
MTCERVFLIS LELAVCAIHP VPGHYRFTWT ARLAFTYAPS VAEADVDVLL SIPMFLRLYL 
       250        260        270        280        290        300 
LGRVMLLHSK IFTDASSRSI GALNKITFNT RFVMKTLMTI CPGTVLLVFS ISSWIIAAWT 
       310        320        330        340        350        360 
VRVCERYHDK QEVTSNFLGA MWLISITFLS IGYGDMVPHT YCGKGVCLLT GIMGAGCTAL 
       370        380        390        400        410        420 
VVAVVARKLE LTKAEKHVHN FMMDTQLTKR VKNAAANVLR ETWLIYKHTR LVKKPDQARV 
       430        440        450        460        470        480 
RKHQRKFLQA IHQAQKLRSV KIEQGKLNDQ ANTLTDLAKT QTVMYDLVSE LHAQHEELEA 
       490        500        510        520        530        540 
RLATLESRLD ALGASLQALP GLIAQAIRPP PPPLPPRPGP GPQDQAARSS PCRWTPVAPS 
   
DCG



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Protease Assignment Confidence:


Evidence Names:


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Protein Neighborhood

Domains & Features

1 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    Q92952-1-unknown MNSHSY... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    Q92952-1-unknown MNSHSY... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt97228

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...PSDCG 543 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    ...PSDCG 543 inferred from isoform by sequence similarity unknown TopFIND inferred from TCt74404

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)