Q92989: Polyribonucleotide 5'-hydroxyl-kinase Clp1 {ECO:0000255|HAMAP-Rule:MF_03035}

General Information

Protein names	- Polyribonucleotide 5'-hydroxyl-kinase Clp1 {ECO:0000255\|HAMAP-Rule:MF_03035} - 2.7.1.78 {ECO:0000255\|HAMAP-Rule:MF_03035} - Polyadenylation factor Clp1 {ECO:0000255\|HAMAP-Rule:MF_03035} - Polynucleotide kinase Clp1 {ECO:0000255\|HAMAP-Rule:MF_03035} - Pre-mRNA cleavage complex II protein Clp1 {ECO:0000255\|HAMAP-Rule:MF_03035}
Gene names	CLP1
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q92989

2 N-termini

1 C-termini

0 Cleavages

0 Substrates

Sequence

        10         20         30         40         50         60
MGEEANDDKK PTTKFELERE TELRFEVEAS QSVQLELLTG MAEIFGTELT RNKKFTFDAG
        70         80         90        100        110        120
AKVAVFTWHG CSVQLSGRTE VAYVSKDTPM LLYLNTHTAL EQMRRQAEKE EERGPRVMVV
       130        140        150        160        170        180
GPTDVGKSTV CRLLLNYAVR LGRRPTYVEL DVGQGSVSIP GTMGALYIER PADVEEGFSI
       190        200        210        220        230        240
QAPLVYHFGS TTPGTNIKLY NKITSRLADV FNQRCEVNRR ASVSGCVINT CGWVKGSGYQ
       250        260        270        280        290        300
ALVHAASAFE VDVVVVLDQE RLYNELKRDL PHFVRTVLLP KSGGVVERSK DFRRECRDER
       310        320        330        340        350        360
IREYFYGFRG CFYPHAFNVK FSDVKIYKVG APTIPDSCLP LGMSQEDNQL KLVPVTPGRD
       370        380        390        400        410        420
MVHHLLSVST AEGTEENLSE TSVAGFIVVT SVDLEHQVFT VLSPAPRPLP KNFLLIMDIR

FMDLK

Isoforms

- Isoform 2 of Polyribonucleotide 5'-hydroxyl-kinase Clp1

Sequence View

Filter Information:

(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

2 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
Q92989-1-unknown	MGEEAN...	1		inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q92989-1-unknown	MGEEAN...	1		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt71015
Q92989-2-acetylation	GEEAND...	2	acetylation-		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345
Q92989-2-acetylation	GEEAND...	2	acetylation-		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345
Q92989-2-acetylation	GEEAND...	2	acetylation-	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt162833

C-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
	...FMDLK	425	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
	...FMDLK	425	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt66633

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)