Q92993: Histone acetyltransferase KAT5

General Information

Protein names	- Histone acetyltransferase KAT5 - 2.3.1.48 {ECO:0000269\|PubMed:10096020, ECO:0000269\|PubMed:12468530, ECO:0000269\|PubMed:29040603, ECO:0000269\|PubMed:30704899} - 60 kDa Tat-interactive protein - Tip60 {ECO:0000303\|PubMed:10096020, ECO:0000303\|PubMed:11416127, ECO:0000303\|PubMed:12801643, ECO:0000303\|PubMed:29040603} - Histone acetyltransferase HTATIP - HIV-1 Tat interactive protein - Lysine acetyltransferase 5 - cPLA(2)-interacting protein
Gene names	KAT5
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q92993

2 N-termini

1 C-termini

0 Cleavages

0 Substrates

Sequence

Isoforms

- Isoform 2 of Histone acetyltransferase KAT5 - Isoform 3 of Histone acetyltransferase KAT5 - Isoform 4 of Histone acetyltransferase KAT5 - Isoform 1 of Histone acetyltransferase KAT5

Sequence View

        10         20         30         40         50         60
MAEVGEIIEG CRLPVLRRNQ DNEDEWPLAE ILSVKDISGR KLFYVHYIDF NKRLDEWVTH
        70         80         90        100        110        120
ERLDLKKIQF PKKEAKTPTK NGLPGSRPGS PEREVPASAQ ASGKTLPIPV QITLRFNLPK
       130        140        150        160        170        180
EREAIPGGEP DQPLSSSSCL QPNHRSTKRK VEVVSPATPV PSETAPASVF PQNGAARRAV
       190        200        210        220        230        240
AAQPGRKRKS NCLGTDEDSQ DSSDGIPSAP RMTGSLVSDR SHDDIVTRMK NIECIELGRH
       250        260        270        280        290        300
RLKPWYFSPY PQELTTLPVL YLCEFCLKYG RSLKCLQRHL TKCDLRHPPG NEIYRKGTIS
       310        320        330        340        350        360
FFEIDGRKNK SYSQNLCLLA KCFLDHKTLY YDTDPFLFYV MTEYDCKGFH IVGYFSKEKE
       370        380        390        400        410        420
STEDYNVACI LTLPPYQRRG YGKLLIEFSY ELSKVEGKTG TPEKPLSDLG LLSYRSYWSQ
       430        440        450        460        470        480
TILEILMGLK SESGERPQIT INEISEITSI KKEDVISTLQ YLNLINYYKG QYILTLSEDI
       490        500        510
VDGHERAMLK RLLRIDSKCL HFTPKDWSKR GKW         10         20         30         40         50         60
MAEVGEIIEG CRLPVLRRNQ DNEDEWPLAE ILSVKDISGR KLFYVHYIDF NKRLDEWVTH
        70         80         90        100        110        120
ERLDLKKIQF PKKEAKTPTK NGLPGSRPGS PEREVPASAQ ASGKTLPIPV QITLRFNLPK
       130        140        150        160        170        180
EREAIPGGEP DQPLSSSSCL QPNHRSTKRK VEVVSPATPV PSETAPASVF PQNGAARRAV
       190        200        210        220        230        240
AAQPGRKRKS NCLGTDEDSQ DSSDGIPSAP RMTGSLVSDR SHDDIVTRMK NIECIELGRH
       250        260        270        280        290        300
RLKPWYFSPY PQELTTLPVL YLCEFCLKYG RSLKCLQRHL TKCDLRHPPG NEIYRKGTIS
       310        320        330        340        350        360
FFEIDGRKNK SYSQNLCLLA KCFLDHKTLY YDTDPFLFYV MTEYDCKGFH IVGYFSKEKE
       370        380        390        400        410        420
STEDYNVACI LTLPPYQRRG YGKLLIEFSY ELSKVEGKTG TPEKPLSDLG LLSYRSYWSQ
       430        440        450        460        470        480
TILEILMGLK SESGERPQIT INEISEITSI KKEDVISTLQ YLNLINYYKG QYILTLSEDI
       490        500        510
VDGHERAMLK RLLRIDSKCL HFTPKDWSKR GKW         10         20         30         40         50         60
MAEVGEIIEG CRLPVLRRNQ DNEDEWPLAE ILSVKDISGR KLFYVHYIDF NKRLDEWVTH
        70         80         90        100        110        120
ERLDLKKIQF PKKEAKTPTK NGLPGSRPGS PEREVPASAQ ASGKTLPIPV QITLRFNLPK
       130        140        150        160        170        180
EREAIPGGEP DQPLSSSSCL QPNHRSTKRK VEVVSPATPV PSETAPASVF PQNGAARRAV
       190        200        210        220        230        240
AAQPGRKRKS NCLGTDEDSQ DSSDGIPSAP RMTGSLVSDR SHDDIVTRMK NIECIELGRH
       250        260        270        280        290        300
RLKPWYFSPY PQELTTLPVL YLCEFCLKYG RSLKCLQRHL TKCDLRHPPG NEIYRKGTIS
       310        320        330        340        350        360
FFEIDGRKNK SYSQNLCLLA KCFLDHKTLY YDTDPFLFYV MTEYDCKGFH IVGYFSKEKE
       370        380        390        400        410        420
STEDYNVACI LTLPPYQRRG YGKLLIEFSY ELSKVEGKTG TPEKPLSDLG LLSYRSYWSQ
       430        440        450        460        470        480
TILEILMGLK SESGERPQIT INEISEITSI KKEDVISTLQ YLNLINYYKG QYILTLSEDI
       490        500        510
VDGHERAMLK RLLRIDSKCL HFTPKDWSKR GKW         10         20         30         40         50         60
MAEVGEIIEG CRLPVLRRNQ DNEDEWPLAE ILSVKDISGR KLFYVHYIDF NKRLDEWVTH
        70         80         90        100        110        120
ERLDLKKIQF PKKEAKTPTK NGLPGSRPGS PEREVPASAQ ASGKTLPIPV QITLRFNLPK
       130        140        150        160        170        180
EREAIPGGEP DQPLSSSSCL QPNHRSTKRK VEVVSPATPV PSETAPASVF PQNGAARRAV
       190        200        210        220        230        240
AAQPGRKRKS NCLGTDEDSQ DSSDGIPSAP RMTGSLVSDR SHDDIVTRMK NIECIELGRH
       250        260        270        280        290        300
RLKPWYFSPY PQELTTLPVL YLCEFCLKYG RSLKCLQRHL TKCDLRHPPG NEIYRKGTIS
       310        320        330        340        350        360
FFEIDGRKNK SYSQNLCLLA KCFLDHKTLY YDTDPFLFYV MTEYDCKGFH IVGYFSKEKE
       370        380        390        400        410        420
STEDYNVACI LTLPPYQRRG YGKLLIEFSY ELSKVEGKTG TPEKPLSDLG LLSYRSYWSQ
       430        440        450        460        470        480
TILEILMGLK SESGERPQIT INEISEITSI KKEDVISTLQ YLNLINYYKG QYILTLSEDI
       490        500        510
VDGHERAMLK RLLRIDSKCL HFTPKDWSKR GKW

Filter Information:

(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

2 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
Q92993-1-unknown	MAEVGE...	1		inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q92993-1-unknown	MAEVGE...	1		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt78582
Q92993-2-acetylation	AEVGEI...	2	acetylation-		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345
Q92993-2-acetylation	AEVGEI...	2	acetylation-		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345
Q92993-2-acetylation	AEVGEI...	2	acetylation-	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt162635

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...KRGKW	513	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...KRGKW	513	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt74200
...KRGKW	513	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt74202
...KRGKW	513	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt74201

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)