Q93038: Tumor necrosis factor receptor superfamily member 25

General Information

Protein names	- Tumor necrosis factor receptor superfamily member 25 - Apo-3 - Apoptosis-inducing receptor AIR - Apoptosis-mediating receptor DR3 - Apoptosis-mediating receptor TRAMP - Death receptor 3 - Lymphocyte-associated receptor of death - LARD - Protein WSL - Protein WSL-1
Gene names	TNFRSF25
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q93038

3 N-termini

2 C-termini

0 Cleavages

0 Substrates

Sequence

Isoforms

- Isoform 2 of Tumor necrosis factor receptor superfamily member 25 - Isoform 3 of Tumor necrosis factor receptor superfamily member 25 - Isoform 4 of Tumor necrosis factor receptor superfamily member 25 - Isoform 5 of Tumor necrosis factor receptor superfamily member 25 - Isoform 6 of Tumor necrosis factor receptor superfamily member 25 - Isoform 7 of Tumor necrosis factor receptor superfamily member 25 - Isoform 8 of Tumor necrosis factor receptor superfamily member 25 - Isoform 9 of Tumor necrosis factor receptor superfamily member 25 - Isoform 10 of Tumor necrosis factor receptor superfamily member 25 - Isoform 11 of Tumor necrosis factor receptor superfamily member 25 - Isoform 12 of Tumor necrosis factor receptor superfamily member 25

Sequence View

        10         20         30         40         50         60
MEQRPRGCAA VAAALLLVLL GARAQGGTRS PRCDCAGDFH KKIGLFCCRG CPAGHYLKAP
        70         80         90        100        110        120
CTEPCGNSTC LVCPQDTFLA WENHHNSECA RCQACDEQAS QVALENCSAV ADTRCGCKPG
       130        140        150        160        170        180
WFVECQVSQC VSSSPFYCQP CLDCGALHRH TRLLCSRRDT DCGTCLPGFY EHGDGCVSCP
       190        200        210        220        230        240
TSTLGSCPER CAAVCGWRQM FWVQVLLAGL VVPLLLGATL TYTYRHCWPH KPLVTADEAG
       250        260        270        280        290        300
MEALTPPPAT HLSPLDSAHT LLAPPDSSEK ICTVQLVGNS WTPGYPETQE ALCPQVTWSW
       310        320        330        340        350        360
DQLPSRALGP AAAPTLSPES PAGSPAMMLQ PGPQLYDVMD AVPARRWKEF VRTLGLREAE
       370        380        390        400        410
IEAVEVEIGR FRDQQYEMLK RWRQQQPAGL GAVYAALERM GLDGCVEDLR SRLQRGP         10         20         30         40         50         60
MEQRPRGCAA VAAALLLVLL GARAQGGTRS PRCDCAGDFH KKIGLFCCRG CPAGHYLKAP
        70         80         90        100        110        120
CTEPCGNSTC LVCPQDTFLA WENHHNSECA RCQACDEQAS QVALENCSAV ADTRCGCKPG
       130        140        150        160        170        180
WFVECQVSQC VSSSPFYCQP CLDCGALHRH TRLLCSRRDT DCGTCLPGFY EHGDGCVSCP
       190        200        210        220        230        240
TSTLGSCPER CAAVCGWRQM FWVQVLLAGL VVPLLLGATL TYTYRHCWPH KPLVTADEAG
       250        260        270        280        290        300
MEALTPPPAT HLSPLDSAHT LLAPPDSSEK ICTVQLVGNS WTPGYPETQE ALCPQVTWSW
       310        320        330        340        350        360
DQLPSRALGP AAAPTLSPES PAGSPAMMLQ PGPQLYDVMD AVPARRWKEF VRTLGLREAE
       370        380        390        400        410
IEAVEVEIGR FRDQQYEMLK RWRQQQPAGL GAVYAALERM GLDGCVEDLR SRLQRGP         10         20         30         40         50         60
MEQRPRGCAA VAAALLLVLL GARAQGGTRS PRCDCAGDFH KKIGLFCCRG CPAGHYLKAP
        70         80         90        100        110        120
CTEPCGNSTC LVCPQDTFLA WENHHNSECA RCQACDEQAS QVALENCSAV ADTRCGCKPG
       130        140        150        160        170        180
WFVECQVSQC VSSSPFYCQP CLDCGALHRH TRLLCSRRDT DCGTCLPGFY EHGDGCVSCP
       190        200        210        220        230        240
TSTLGSCPER CAAVCGWRQM FWVQVLLAGL VVPLLLGATL TYTYRHCWPH KPLVTADEAG
       250        260        270        280        290        300
MEALTPPPAT HLSPLDSAHT LLAPPDSSEK ICTVQLVGNS WTPGYPETQE ALCPQVTWSW
       310        320        330        340        350        360
DQLPSRALGP AAAPTLSPES PAGSPAMMLQ PGPQLYDVMD AVPARRWKEF VRTLGLREAE
       370        380        390        400        410
IEAVEVEIGR FRDQQYEMLK RWRQQQPAGL GAVYAALERM GLDGCVEDLR SRLQRGP         10         20         30         40         50         60
MEQRPRGCAA VAAALLLVLL GARAQGGTRS PRCDCAGDFH KKIGLFCCRG CPAGHYLKAP
        70         80         90        100        110        120
CTEPCGNSTC LVCPQDTFLA WENHHNSECA RCQACDEQAS QVALENCSAV ADTRCGCKPG
       130        140        150        160        170        180
WFVECQVSQC VSSSPFYCQP CLDCGALHRH TRLLCSRRDT DCGTCLPGFY EHGDGCVSCP
       190        200        210        220        230        240
TSTLGSCPER CAAVCGWRQM FWVQVLLAGL VVPLLLGATL TYTYRHCWPH KPLVTADEAG
       250        260        270        280        290        300
MEALTPPPAT HLSPLDSAHT LLAPPDSSEK ICTVQLVGNS WTPGYPETQE ALCPQVTWSW
       310        320        330        340        350        360
DQLPSRALGP AAAPTLSPES PAGSPAMMLQ PGPQLYDVMD AVPARRWKEF VRTLGLREAE
       370        380        390        400        410
IEAVEVEIGR FRDQQYEMLK RWRQQQPAGL GAVYAALERM GLDGCVEDLR SRLQRGP         10         20         30         40         50         60
MEQRPRGCAA VAAALLLVLL GARAQGGTRS PRCDCAGDFH KKIGLFCCRG CPAGHYLKAP
        70         80         90        100        110        120
CTEPCGNSTC LVCPQDTFLA WENHHNSECA RCQACDEQAS QVALENCSAV ADTRCGCKPG
       130        140        150        160        170        180
WFVECQVSQC VSSSPFYCQP CLDCGALHRH TRLLCSRRDT DCGTCLPGFY EHGDGCVSCP
       190        200        210        220        230        240
TSTLGSCPER CAAVCGWRQM FWVQVLLAGL VVPLLLGATL TYTYRHCWPH KPLVTADEAG
       250        260        270        280        290        300
MEALTPPPAT HLSPLDSAHT LLAPPDSSEK ICTVQLVGNS WTPGYPETQE ALCPQVTWSW
       310        320        330        340        350        360
DQLPSRALGP AAAPTLSPES PAGSPAMMLQ PGPQLYDVMD AVPARRWKEF VRTLGLREAE
       370        380        390        400        410
IEAVEVEIGR FRDQQYEMLK RWRQQQPAGL GAVYAALERM GLDGCVEDLR SRLQRGP         10         20         30         40         50         60
MEQRPRGCAA VAAALLLVLL GARAQGGTRS PRCDCAGDFH KKIGLFCCRG CPAGHYLKAP
        70         80         90        100        110        120
CTEPCGNSTC LVCPQDTFLA WENHHNSECA RCQACDEQAS QVALENCSAV ADTRCGCKPG
       130        140        150        160        170        180
WFVECQVSQC VSSSPFYCQP CLDCGALHRH TRLLCSRRDT DCGTCLPGFY EHGDGCVSCP
       190        200        210        220        230        240
TSTLGSCPER CAAVCGWRQM FWVQVLLAGL VVPLLLGATL TYTYRHCWPH KPLVTADEAG
       250        260        270        280        290        300
MEALTPPPAT HLSPLDSAHT LLAPPDSSEK ICTVQLVGNS WTPGYPETQE ALCPQVTWSW
       310        320        330        340        350        360
DQLPSRALGP AAAPTLSPES PAGSPAMMLQ PGPQLYDVMD AVPARRWKEF VRTLGLREAE
       370        380        390        400        410
IEAVEVEIGR FRDQQYEMLK RWRQQQPAGL GAVYAALERM GLDGCVEDLR SRLQRGP         10         20         30         40         50         60
MEQRPRGCAA VAAALLLVLL GARAQGGTRS PRCDCAGDFH KKIGLFCCRG CPAGHYLKAP
        70         80         90        100        110        120
CTEPCGNSTC LVCPQDTFLA WENHHNSECA RCQACDEQAS QVALENCSAV ADTRCGCKPG
       130        140        150        160        170        180
WFVECQVSQC VSSSPFYCQP CLDCGALHRH TRLLCSRRDT DCGTCLPGFY EHGDGCVSCP
       190        200        210        220        230        240
TSTLGSCPER CAAVCGWRQM FWVQVLLAGL VVPLLLGATL TYTYRHCWPH KPLVTADEAG
       250        260        270        280        290        300
MEALTPPPAT HLSPLDSAHT LLAPPDSSEK ICTVQLVGNS WTPGYPETQE ALCPQVTWSW
       310        320        330        340        350        360
DQLPSRALGP AAAPTLSPES PAGSPAMMLQ PGPQLYDVMD AVPARRWKEF VRTLGLREAE
       370        380        390        400        410
IEAVEVEIGR FRDQQYEMLK RWRQQQPAGL GAVYAALERM GLDGCVEDLR SRLQRGP         10         20         30         40         50         60
MEQRPRGCAA VAAALLLVLL GARAQGGTRS PRCDCAGDFH KKIGLFCCRG CPAGHYLKAP
        70         80         90        100        110        120
CTEPCGNSTC LVCPQDTFLA WENHHNSECA RCQACDEQAS QVALENCSAV ADTRCGCKPG
       130        140        150        160        170        180
WFVECQVSQC VSSSPFYCQP CLDCGALHRH TRLLCSRRDT DCGTCLPGFY EHGDGCVSCP
       190        200        210        220        230        240
TSTLGSCPER CAAVCGWRQM FWVQVLLAGL VVPLLLGATL TYTYRHCWPH KPLVTADEAG
       250        260        270        280        290        300
MEALTPPPAT HLSPLDSAHT LLAPPDSSEK ICTVQLVGNS WTPGYPETQE ALCPQVTWSW
       310        320        330        340        350        360
DQLPSRALGP AAAPTLSPES PAGSPAMMLQ PGPQLYDVMD AVPARRWKEF VRTLGLREAE
       370        380        390        400        410
IEAVEVEIGR FRDQQYEMLK RWRQQQPAGL GAVYAALERM GLDGCVEDLR SRLQRGP         10         20         30         40         50         60
MEQRPRGCAA VAAALLLVLL GARAQGGTRS PRCDCAGDFH KKIGLFCCRG CPAGHYLKAP
        70         80         90        100        110        120
CTEPCGNSTC LVCPQDTFLA WENHHNSECA RCQACDEQAS QVALENCSAV ADTRCGCKPG
       130        140        150        160        170        180
WFVECQVSQC VSSSPFYCQP CLDCGALHRH TRLLCSRRDT DCGTCLPGFY EHGDGCVSCP
       190        200        210        220        230        240
TSTLGSCPER CAAVCGWRQM FWVQVLLAGL VVPLLLGATL TYTYRHCWPH KPLVTADEAG
       250        260        270        280        290        300
MEALTPPPAT HLSPLDSAHT LLAPPDSSEK ICTVQLVGNS WTPGYPETQE ALCPQVTWSW
       310        320        330        340        350        360
DQLPSRALGP AAAPTLSPES PAGSPAMMLQ PGPQLYDVMD AVPARRWKEF VRTLGLREAE
       370        380        390        400        410
IEAVEVEIGR FRDQQYEMLK RWRQQQPAGL GAVYAALERM GLDGCVEDLR SRLQRGP         10         20         30         40         50         60
MEQRPRGCAA VAAALLLVLL GARAQGGTRS PRCDCAGDFH KKIGLFCCRG CPAGHYLKAP
        70         80         90        100        110        120
CTEPCGNSTC LVCPQDTFLA WENHHNSECA RCQACDEQAS QVALENCSAV ADTRCGCKPG
       130        140        150        160        170        180
WFVECQVSQC VSSSPFYCQP CLDCGALHRH TRLLCSRRDT DCGTCLPGFY EHGDGCVSCP
       190        200        210        220        230        240
TSTLGSCPER CAAVCGWRQM FWVQVLLAGL VVPLLLGATL TYTYRHCWPH KPLVTADEAG
       250        260        270        280        290        300
MEALTPPPAT HLSPLDSAHT LLAPPDSSEK ICTVQLVGNS WTPGYPETQE ALCPQVTWSW
       310        320        330        340        350        360
DQLPSRALGP AAAPTLSPES PAGSPAMMLQ PGPQLYDVMD AVPARRWKEF VRTLGLREAE
       370        380        390        400        410
IEAVEVEIGR FRDQQYEMLK RWRQQQPAGL GAVYAALERM GLDGCVEDLR SRLQRGP         10         20         30         40         50         60
MEQRPRGCAA VAAALLLVLL GARAQGGTRS PRCDCAGDFH KKIGLFCCRG CPAGHYLKAP
        70         80         90        100        110        120
CTEPCGNSTC LVCPQDTFLA WENHHNSECA RCQACDEQAS QVALENCSAV ADTRCGCKPG
       130        140        150        160        170        180
WFVECQVSQC VSSSPFYCQP CLDCGALHRH TRLLCSRRDT DCGTCLPGFY EHGDGCVSCP
       190        200        210        220        230        240
TSTLGSCPER CAAVCGWRQM FWVQVLLAGL VVPLLLGATL TYTYRHCWPH KPLVTADEAG
       250        260        270        280        290        300
MEALTPPPAT HLSPLDSAHT LLAPPDSSEK ICTVQLVGNS WTPGYPETQE ALCPQVTWSW
       310        320        330        340        350        360
DQLPSRALGP AAAPTLSPES PAGSPAMMLQ PGPQLYDVMD AVPARRWKEF VRTLGLREAE
       370        380        390        400        410
IEAVEVEIGR FRDQQYEMLK RWRQQQPAGL GAVYAALERM GLDGCVEDLR SRLQRGP

Filter Information:

(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

3 N-termini - 2 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Evidence name
Q93038-1-unknown	MEQRPR...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt92705
Q93038-1-unknown	MEQRPR...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt92706
Q93038-1-unknown	MEQRPR...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt92707
Q93038-1-unknown	MEQRPR...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt92708
Q93038-1-unknown	MEQRPR...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt92709
Q93038-1-unknown	MEQRPR...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt92710
Q93038-1-unknown	MEQRPR...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt92711
Q93038-1-unknown	MEQRPR...	1	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt92712
Q93038-25-unknown	QGGTRS...	25	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
Q93038-25-unknown	QGGTRS...	25	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt113836
Q93038-25-unknown	QGGTRS...	25	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt113837
Q93038-25-unknown	QGGTRS...	25	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt113838
Q93038-25-unknown	QGGTRS...	25	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt113839
Q93038-25-unknown	QGGTRS...	25	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt113840
Q93038-25-unknown	QGGTRS...	25	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt113841
Q93038-25-unknown	QGGTRS...	25	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt113842
Q93038-25-unknown	QGGTRS...	25	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt113843
Q93038-200-unknown	MFWVQV...	200	inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000465381
Q93038-200-unknown	MFWVQV...	200	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt198056
Q93038-200-unknown	MFWVQV...	200	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt198057
Q93038-200-unknown	MFWVQV...	200	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...VSCPTS	181	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt88327
...VSCPTS	181	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt88326
...VSCPTS	181	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt91641
...VSCPTS	181	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt91642
...VSCPTS	181	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt91643
...VSCPTS	181	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt91644
...LQRGP	417	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...LQRGP	417	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt88329
...LQRGP	417	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt88330
...LQRGP	417	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt88323

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)