Q969M7: NEDD8-conjugating enzyme UBE2F

General Information

Protein names	- NEDD8-conjugating enzyme UBE2F - 2.3.2.32 {ECO:0000269\|PubMed:23201271} - NEDD8 carrier protein UBE2F - NEDD8 protein ligase UBE2F - NEDD8-conjugating enzyme 2 - RING-type E3 NEDD8 transferase UBE2F - Ubiquitin-conjugating enzyme E2 F
Gene names	UBE2F
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q969M7

2 N-termini

1 C-termini

0 Cleavages

0 Substrates

Sequence

Isoforms

- Isoform 2 of NEDD8-conjugating enzyme UBE2F - Isoform 3 of NEDD8-conjugating enzyme UBE2F - Isoform 4 of NEDD8-conjugating enzyme UBE2F - Isoform 5 of NEDD8-conjugating enzyme UBE2F - Isoform 6 of NEDD8-conjugating enzyme UBE2F - Isoform 7 of NEDD8-conjugating enzyme UBE2F

Sequence View

        10         20         30         40         50         60
MLTLASKLKR DDGLKGSRTA ATASDSTRRV SVRDKLLVKE VAELEANLPC TCKVHFPDPN
        70         80         90        100        110        120
KLHCFQLTVT PDEGYYQGGK FQFETEVPDA YNMVPPKVKC LTKIWHPNIT ETGEICLSLL
       130        140        150        160        170        180
REHSIDGTGW APTRTLKDVV WGLNSLFTDL LNFDDPLNIE AAEHHLRDKE DFRNKVDDYI

KRYAR         10         20         30         40         50         60
MLTLASKLKR DDGLKGSRTA ATASDSTRRV SVRDKLLVKE VAELEANLPC TCKVHFPDPN
        70         80         90        100        110        120
KLHCFQLTVT PDEGYYQGGK FQFETEVPDA YNMVPPKVKC LTKIWHPNIT ETGEICLSLL
       130        140        150        160        170        180
REHSIDGTGW APTRTLKDVV WGLNSLFTDL LNFDDPLNIE AAEHHLRDKE DFRNKVDDYI

KRYAR         10         20         30         40         50         60
MLTLASKLKR DDGLKGSRTA ATASDSTRRV SVRDKLLVKE VAELEANLPC TCKVHFPDPN
        70         80         90        100        110        120
KLHCFQLTVT PDEGYYQGGK FQFETEVPDA YNMVPPKVKC LTKIWHPNIT ETGEICLSLL
       130        140        150        160        170        180
REHSIDGTGW APTRTLKDVV WGLNSLFTDL LNFDDPLNIE AAEHHLRDKE DFRNKVDDYI

KRYAR         10         20         30         40         50         60
MLTLASKLKR DDGLKGSRTA ATASDSTRRV SVRDKLLVKE VAELEANLPC TCKVHFPDPN
        70         80         90        100        110        120
KLHCFQLTVT PDEGYYQGGK FQFETEVPDA YNMVPPKVKC LTKIWHPNIT ETGEICLSLL
       130        140        150        160        170        180
REHSIDGTGW APTRTLKDVV WGLNSLFTDL LNFDDPLNIE AAEHHLRDKE DFRNKVDDYI

KRYAR         10         20         30         40         50         60
MLTLASKLKR DDGLKGSRTA ATASDSTRRV SVRDKLLVKE VAELEANLPC TCKVHFPDPN
        70         80         90        100        110        120
KLHCFQLTVT PDEGYYQGGK FQFETEVPDA YNMVPPKVKC LTKIWHPNIT ETGEICLSLL
       130        140        150        160        170        180
REHSIDGTGW APTRTLKDVV WGLNSLFTDL LNFDDPLNIE AAEHHLRDKE DFRNKVDDYI

KRYAR         10         20         30         40         50         60
MLTLASKLKR DDGLKGSRTA ATASDSTRRV SVRDKLLVKE VAELEANLPC TCKVHFPDPN
        70         80         90        100        110        120
KLHCFQLTVT PDEGYYQGGK FQFETEVPDA YNMVPPKVKC LTKIWHPNIT ETGEICLSLL
       130        140        150        160        170        180
REHSIDGTGW APTRTLKDVV WGLNSLFTDL LNFDDPLNIE AAEHHLRDKE DFRNKVDDYI

KRYAR

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(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

2 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
Q969M7-1-Acetylation	MLTLAS...	1	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q969M7-1-Acetylation	MLTLAS...	1	acetylation-		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345
Q969M7-1-Acetylation	MLTLAS...	1	acetylation-		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345
Q969M7-1-Acetylation	MLTLAS...	1	acetylation-	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt101656
Q969M7-1-Acetylation	MLTLAS...	1	acetylation-	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt101657
Q969M7-1-Acetylation	MLTLAS...	1	acetylation-	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt101658
Q969M7-1-Acetylation	MLTLAS...	1	acetylation-	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt101659
Q969M7-1-unknown	MLTLAS...	1		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt93597
Q969M7-1-unknown	MLTLAS...	1		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt93598
Q969M7-1-unknown	MLTLAS...	1		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt93599
Q969M7-1-unknown	MLTLAS...	1		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt93600

C-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
	...KRYAR	185	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
	...KRYAR	185	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt89216

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)