Q969N2: GPI transamidase component PIG-T

General Information

Protein names	- GPI transamidase component PIG-T - Phosphatidylinositol-glycan biosynthesis class T protein
Gene names	PIGT
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q969N2

3 N-termini

1 C-termini

0 Cleavages

0 Substrates

Sequence

Isoforms

- Isoform 2 of GPI transamidase component PIG-T - Isoform 3 of GPI transamidase component PIG-T - Isoform 4 of GPI transamidase component PIG-T - Isoform 5 of GPI transamidase component PIG-T - Isoform 6 of GPI transamidase component PIG-T

Sequence View

        10         20         30         40         50         60
MAAAMPLALL VLLLLGPGGW CLAEPPRDSL REELVITPLP SGDVAATFQF RTRWDSELQR
        70         80         90        100        110        120
EGVSHYRLFP KALGQLISKY SLRELHLSFT QGFWRTRYWG PPFLQAPSGA ELWVWFQDTV
       130        140        150        160        170        180
TDVDKSWKEL SNVLSGIFCA SLNFIDSTNT VTPTASFKPL GLANDTDHYF LRYAVLPREV
       190        200        210        220        230        240
VCTENLTPWK KLLPCSSKAG LSVLLKADRL FHTSYHSQAV HIRPVCRNAR CTSISWELRQ
       250        260        270        280        290        300
TLSVVFDAFI TGQGKKDWSL FRMFSRTLTE PCPLASESRV YVDITTYNQD NETLEVHPPP
       310        320        330        340        350        360
TTTYQDVILG TRKTYAIYDL LDTAMINNSR NLNIQLKWKR PPENEAPPVP FLHAQRYVSG
       370        380        390        400        410        420
YGLQKGELST LLYNTHPYRA FPVLLLDTVP WYLRLYVHTL TITSKGKENK PSYIHYQPAQ
       430        440        450        460        470        480
DRLQPHLLEM LIQLPANSVT KVSIQFERAL LKWTEYTPDP NHGFYVSPSV LSALVPSMVA
       490        500        510        520        530        540
AKPVDWEESP LFNSLFPVSD GSNYFVRLYT EPLLVNLPTP DFSMPYNVIC LTCTVVAVCY
       550        560        570
GSFYNLLTRT FHIEEPRTGG LAKRLANLIR RARGVPPL         10         20         30         40         50         60
MAAAMPLALL VLLLLGPGGW CLAEPPRDSL REELVITPLP SGDVAATFQF RTRWDSELQR
        70         80         90        100        110        120
EGVSHYRLFP KALGQLISKY SLRELHLSFT QGFWRTRYWG PPFLQAPSGA ELWVWFQDTV
       130        140        150        160        170        180
TDVDKSWKEL SNVLSGIFCA SLNFIDSTNT VTPTASFKPL GLANDTDHYF LRYAVLPREV
       190        200        210        220        230        240
VCTENLTPWK KLLPCSSKAG LSVLLKADRL FHTSYHSQAV HIRPVCRNAR CTSISWELRQ
       250        260        270        280        290        300
TLSVVFDAFI TGQGKKDWSL FRMFSRTLTE PCPLASESRV YVDITTYNQD NETLEVHPPP
       310        320        330        340        350        360
TTTYQDVILG TRKTYAIYDL LDTAMINNSR NLNIQLKWKR PPENEAPPVP FLHAQRYVSG
       370        380        390        400        410        420
YGLQKGELST LLYNTHPYRA FPVLLLDTVP WYLRLYVHTL TITSKGKENK PSYIHYQPAQ
       430        440        450        460        470        480
DRLQPHLLEM LIQLPANSVT KVSIQFERAL LKWTEYTPDP NHGFYVSPSV LSALVPSMVA
       490        500        510        520        530        540
AKPVDWEESP LFNSLFPVSD GSNYFVRLYT EPLLVNLPTP DFSMPYNVIC LTCTVVAVCY
       550        560        570
GSFYNLLTRT FHIEEPRTGG LAKRLANLIR RARGVPPL         10         20         30         40         50         60
MAAAMPLALL VLLLLGPGGW CLAEPPRDSL REELVITPLP SGDVAATFQF RTRWDSELQR
        70         80         90        100        110        120
EGVSHYRLFP KALGQLISKY SLRELHLSFT QGFWRTRYWG PPFLQAPSGA ELWVWFQDTV
       130        140        150        160        170        180
TDVDKSWKEL SNVLSGIFCA SLNFIDSTNT VTPTASFKPL GLANDTDHYF LRYAVLPREV
       190        200        210        220        230        240
VCTENLTPWK KLLPCSSKAG LSVLLKADRL FHTSYHSQAV HIRPVCRNAR CTSISWELRQ
       250        260        270        280        290        300
TLSVVFDAFI TGQGKKDWSL FRMFSRTLTE PCPLASESRV YVDITTYNQD NETLEVHPPP
       310        320        330        340        350        360
TTTYQDVILG TRKTYAIYDL LDTAMINNSR NLNIQLKWKR PPENEAPPVP FLHAQRYVSG
       370        380        390        400        410        420
YGLQKGELST LLYNTHPYRA FPVLLLDTVP WYLRLYVHTL TITSKGKENK PSYIHYQPAQ
       430        440        450        460        470        480
DRLQPHLLEM LIQLPANSVT KVSIQFERAL LKWTEYTPDP NHGFYVSPSV LSALVPSMVA
       490        500        510        520        530        540
AKPVDWEESP LFNSLFPVSD GSNYFVRLYT EPLLVNLPTP DFSMPYNVIC LTCTVVAVCY
       550        560        570
GSFYNLLTRT FHIEEPRTGG LAKRLANLIR RARGVPPL         10         20         30         40         50         60
MAAAMPLALL VLLLLGPGGW CLAEPPRDSL REELVITPLP SGDVAATFQF RTRWDSELQR
        70         80         90        100        110        120
EGVSHYRLFP KALGQLISKY SLRELHLSFT QGFWRTRYWG PPFLQAPSGA ELWVWFQDTV
       130        140        150        160        170        180
TDVDKSWKEL SNVLSGIFCA SLNFIDSTNT VTPTASFKPL GLANDTDHYF LRYAVLPREV
       190        200        210        220        230        240
VCTENLTPWK KLLPCSSKAG LSVLLKADRL FHTSYHSQAV HIRPVCRNAR CTSISWELRQ
       250        260        270        280        290        300
TLSVVFDAFI TGQGKKDWSL FRMFSRTLTE PCPLASESRV YVDITTYNQD NETLEVHPPP
       310        320        330        340        350        360
TTTYQDVILG TRKTYAIYDL LDTAMINNSR NLNIQLKWKR PPENEAPPVP FLHAQRYVSG
       370        380        390        400        410        420
YGLQKGELST LLYNTHPYRA FPVLLLDTVP WYLRLYVHTL TITSKGKENK PSYIHYQPAQ
       430        440        450        460        470        480
DRLQPHLLEM LIQLPANSVT KVSIQFERAL LKWTEYTPDP NHGFYVSPSV LSALVPSMVA
       490        500        510        520        530        540
AKPVDWEESP LFNSLFPVSD GSNYFVRLYT EPLLVNLPTP DFSMPYNVIC LTCTVVAVCY
       550        560        570
GSFYNLLTRT FHIEEPRTGG LAKRLANLIR RARGVPPL         10         20         30         40         50         60
MAAAMPLALL VLLLLGPGGW CLAEPPRDSL REELVITPLP SGDVAATFQF RTRWDSELQR
        70         80         90        100        110        120
EGVSHYRLFP KALGQLISKY SLRELHLSFT QGFWRTRYWG PPFLQAPSGA ELWVWFQDTV
       130        140        150        160        170        180
TDVDKSWKEL SNVLSGIFCA SLNFIDSTNT VTPTASFKPL GLANDTDHYF LRYAVLPREV
       190        200        210        220        230        240
VCTENLTPWK KLLPCSSKAG LSVLLKADRL FHTSYHSQAV HIRPVCRNAR CTSISWELRQ
       250        260        270        280        290        300
TLSVVFDAFI TGQGKKDWSL FRMFSRTLTE PCPLASESRV YVDITTYNQD NETLEVHPPP
       310        320        330        340        350        360
TTTYQDVILG TRKTYAIYDL LDTAMINNSR NLNIQLKWKR PPENEAPPVP FLHAQRYVSG
       370        380        390        400        410        420
YGLQKGELST LLYNTHPYRA FPVLLLDTVP WYLRLYVHTL TITSKGKENK PSYIHYQPAQ
       430        440        450        460        470        480
DRLQPHLLEM LIQLPANSVT KVSIQFERAL LKWTEYTPDP NHGFYVSPSV LSALVPSMVA
       490        500        510        520        530        540
AKPVDWEESP LFNSLFPVSD GSNYFVRLYT EPLLVNLPTP DFSMPYNVIC LTCTVVAVCY
       550        560        570
GSFYNLLTRT FHIEEPRTGG LAKRLANLIR RARGVPPL

Filter Information:

(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

3 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
Q969N2-1-unknown	MAAAMP...	1	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt85217
Q969N2-1-unknown	MAAAMP...	1	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt85219
Q969N2-1-unknown	MAAAMP...	1	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt85220
Q969N2-1-unknown	MAAAMP...	1	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt85221
Q969N2-22-unknown	LAEPPR...	22	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q969N2-22-unknown	LAEPPR...	22	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt113004
Q969N2-22-unknown	LAEPPR...	22	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt113005
Q969N2-22-unknown	LAEPPR...	22	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt113006
Q969N2-22-unknown	LAEPPR...	22	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt113007
Q969N2-22-	LAEPPR...	22		Subtiligase Based Positive Selection		Wells	apoptosis_U266_bortezomib_induced	23264352

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...GVPPL	578	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...GVPPL	578	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt80836
...GVPPL	578	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt80835
...GVPPL	578	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt80837
...GVPPL	578	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt80839
...GVPPL	578	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt80838

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)