TopFIND 4.0

Q969P0: Immunoglobulin superfamily member 8

General Information

Protein names
- Immunoglobulin superfamily member 8
- IgSF8
- CD81 partner 3
- Glu-Trp-Ile EWI motif-containing protein 2
- EWI-2
- Keratinocytes-associated transmembrane protein 4
- KCT-4
- LIR-D1
- Prostaglandin regulatory-like protein
- PGRL
- CD316
Gene names IGSF8
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID Q969P0

2

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MGALRPTLLP PSLPLLLLLM LGMGCWAREV LVPEGPLYRV AGTAVSISCN VTGYEGPAQQ 
        70         80         90        100        110        120 
NFEWFLYRPE APDTALGIVS TKDTQFSYAV FKSRVVAGEV QVQRLQGDAV VLKIARLQAQ 
       130        140        150        160        170        180 
DAGIYECHTP STDTRYLGSY SGKVELRVLP DVLQVSAAPP GPRGRQAPTS PPRMTVHEGQ 
       190        200        210        220        230        240 
ELALGCLART STQKHTHLAV SFGRSVPEAP VGRSTLQEVV GIRSDLAVEA GAPYAERLAA 
       250        260        270        280        290        300 
GELRLGKEGT DRYRMVVGGA QAGDAGTYHC TAAEWIQDPD GSWAQIAEKR AVLAHVDVQT 
       310        320        330        340        350        360 
LSSQLAVTVG PGERRIGPGE PLELLCNVSG ALPPAGRHAA YSVGWEMAPA GAPGPGRLVA 
       370        380        390        400        410        420 
QLDTEGVGSL GPGYEGRHIA MEKVASRTYR LRLEAARPGD AGTYRCLAKA YVRGSGTRLR 
       430        440        450        460        470        480 
EAASARSRPL PVHVREEGVV LEAVAWLAGG TVYRGETASL LCNISVRGGP PGLRLAASWW 
       490        500        510        520        530        540 
VERPEDGELS SVPAQLVGGV GQDGVAELGV RPGGGPVSVE LVGPRSHRLR LHSLGPEDEG 
       550        560        570        580        590        600 
VYHCAPSAWV QHADYSWYQA GSARSGPVTV YPYMHALDTL FVPLLVGTGV ALVTGATVLG 
       610    
TITCCFMKRL RKR

Isoforms

- Isoform 2 of Immunoglobulin superfamily member 8 - Isoform 3 of Immunoglobulin superfamily member 8

Sequence View

        10         20         30         40         50         60 
MGALRPTLLP PSLPLLLLLM LGMGCWAREV LVPEGPLYRV AGTAVSISCN VTGYEGPAQQ 
        70         80         90        100        110        120 
NFEWFLYRPE APDTALGIVS TKDTQFSYAV FKSRVVAGEV QVQRLQGDAV VLKIARLQAQ 
       130        140        150        160        170        180 
DAGIYECHTP STDTRYLGSY SGKVELRVLP DVLQVSAAPP GPRGRQAPTS PPRMTVHEGQ 
       190        200        210        220        230        240 
ELALGCLART STQKHTHLAV SFGRSVPEAP VGRSTLQEVV GIRSDLAVEA GAPYAERLAA 
       250        260        270        280        290        300 
GELRLGKEGT DRYRMVVGGA QAGDAGTYHC TAAEWIQDPD GSWAQIAEKR AVLAHVDVQT 
       310        320        330        340        350        360 
LSSQLAVTVG PGERRIGPGE PLELLCNVSG ALPPAGRHAA YSVGWEMAPA GAPGPGRLVA 
       370        380        390        400        410        420 
QLDTEGVGSL GPGYEGRHIA MEKVASRTYR LRLEAARPGD AGTYRCLAKA YVRGSGTRLR 
       430        440        450        460        470        480 
EAASARSRPL PVHVREEGVV LEAVAWLAGG TVYRGETASL LCNISVRGGP PGLRLAASWW 
       490        500        510        520        530        540 
VERPEDGELS SVPAQLVGGV GQDGVAELGV RPGGGPVSVE LVGPRSHRLR LHSLGPEDEG 
       550        560        570        580        590        600 
VYHCAPSAWV QHADYSWYQA GSARSGPVTV YPYMHALDTL FVPLLVGTGV ALVTGATVLG 
       610    
TITCCFMKRL RKR         10         20         30         40         50         60 
MGALRPTLLP PSLPLLLLLM LGMGCWAREV LVPEGPLYRV AGTAVSISCN VTGYEGPAQQ 
        70         80         90        100        110        120 
NFEWFLYRPE APDTALGIVS TKDTQFSYAV FKSRVVAGEV QVQRLQGDAV VLKIARLQAQ 
       130        140        150        160        170        180 
DAGIYECHTP STDTRYLGSY SGKVELRVLP DVLQVSAAPP GPRGRQAPTS PPRMTVHEGQ 
       190        200        210        220        230        240 
ELALGCLART STQKHTHLAV SFGRSVPEAP VGRSTLQEVV GIRSDLAVEA GAPYAERLAA 
       250        260        270        280        290        300 
GELRLGKEGT DRYRMVVGGA QAGDAGTYHC TAAEWIQDPD GSWAQIAEKR AVLAHVDVQT 
       310        320        330        340        350        360 
LSSQLAVTVG PGERRIGPGE PLELLCNVSG ALPPAGRHAA YSVGWEMAPA GAPGPGRLVA 
       370        380        390        400        410        420 
QLDTEGVGSL GPGYEGRHIA MEKVASRTYR LRLEAARPGD AGTYRCLAKA YVRGSGTRLR 
       430        440        450        460        470        480 
EAASARSRPL PVHVREEGVV LEAVAWLAGG TVYRGETASL LCNISVRGGP PGLRLAASWW 
       490        500        510        520        530        540 
VERPEDGELS SVPAQLVGGV GQDGVAELGV RPGGGPVSVE LVGPRSHRLR LHSLGPEDEG 
       550        560        570        580        590        600 
VYHCAPSAWV QHADYSWYQA GSARSGPVTV YPYMHALDTL FVPLLVGTGV ALVTGATVLG 
       610    
TITCCFMKRL RKR



Filter Information:


(REFRESH)

Directness:


Physiological Relevance:


Evidence Codes:


Methodology:


Perturbation of System:


Biological System:


Protease Assignment Confidence:


Evidence Names:


Database:


Lab:



Protein Neighborhood

Domains & Features

2 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    Q969P0-1-unknown MGALRP... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt77669
    Q969P0-28-unknown REVLVP... 28 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    Q969P0-28-unknown REVLVP... 28 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt114349

C-termini

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)