TopFIND 4.0

Q96A23: Copine-4 {ECO:0000305}

General Information

Protein names
- Copine-4 {ECO:0000305}
- Copine IV {ECO:0000250|UniProtKB:Q99829, ECO:0000312|HGNC:HGNC:2317}
- Copine-8 {ECO:0000303|PubMed:12670487}
Gene names CPNE4
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID Q96A23

1

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MKKMSNIYES AANTLGIFNS PCLTKVELRV ACKGISDRDA LSKPDPCVIL KMQSHGQWFE 
        70         80         90        100        110        120 
VDRTEVIRTC INPVYSKLFT VDFYFEEVQR LRFEVHDISS NHNGLKEADF LGGMECTLGQ 
       130        140        150        160        170        180 
IVSQRKLSKS LLKHGNTAGK SSITVIAEEL SGNDDYVELA FNARKLDDKD FFSKSDPFLE 
       190        200        210        220        230        240 
IFRMNDDATQ QLVHRTEVVM NNLSPAWKSF KVSVNSLCSG DPDRRLKCIV WDWDSNGKHD 
       250        260        270        280        290        300 
FIGEFTSTFK EMRGAMEGKQ VQWECINPKY KAKKKNYKNS GTVILNLCKI HKMHSFLDYI 
       310        320        330        340        350        360 
MGGCQIQFTV AIDFTASNGD PRNSCSLHYI HPYQPNEYLK ALVAVGEICQ DYDSDKMFPA 
       370        380        390        400        410        420 
FGFGARIPPE YTVSHDFAIN FNEDNPECAG IQGVVEAYQS CLPKLQLYGP TNIAPIIQKV 
       430        440        450        460        470        480 
AKSASEETNT KEASQYFILL ILTDGVITDM ADTREAIVHA SHLPMSVIIV GVGNADFSDM 
       490        500        510        520        530        540 
QMLDGDDGIL RSPKGEPVLR DIVQFVPFRN FKHASPAALA KSVLAEVPNQ VVDYYNGKGI 
       550    
KPKCSSEMYE SSRTLAP

Isoforms

- Isoform 2 of Copine-4

Sequence View

        10         20         30         40         50         60 
MKKMSNIYES AANTLGIFNS PCLTKVELRV ACKGISDRDA LSKPDPCVIL KMQSHGQWFE 
        70         80         90        100        110        120 
VDRTEVIRTC INPVYSKLFT VDFYFEEVQR LRFEVHDISS NHNGLKEADF LGGMECTLGQ 
       130        140        150        160        170        180 
IVSQRKLSKS LLKHGNTAGK SSITVIAEEL SGNDDYVELA FNARKLDDKD FFSKSDPFLE 
       190        200        210        220        230        240 
IFRMNDDATQ QLVHRTEVVM NNLSPAWKSF KVSVNSLCSG DPDRRLKCIV WDWDSNGKHD 
       250        260        270        280        290        300 
FIGEFTSTFK EMRGAMEGKQ VQWECINPKY KAKKKNYKNS GTVILNLCKI HKMHSFLDYI 
       310        320        330        340        350        360 
MGGCQIQFTV AIDFTASNGD PRNSCSLHYI HPYQPNEYLK ALVAVGEICQ DYDSDKMFPA 
       370        380        390        400        410        420 
FGFGARIPPE YTVSHDFAIN FNEDNPECAG IQGVVEAYQS CLPKLQLYGP TNIAPIIQKV 
       430        440        450        460        470        480 
AKSASEETNT KEASQYFILL ILTDGVITDM ADTREAIVHA SHLPMSVIIV GVGNADFSDM 
       490        500        510        520        530        540 
QMLDGDDGIL RSPKGEPVLR DIVQFVPFRN FKHASPAALA KSVLAEVPNQ VVDYYNGKGI 
       550    
KPKCSSEMYE SSRTLAP



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(REFRESH)

Directness:


Physiological Relevance:


Evidence Codes:


Methodology:


Perturbation of System:


Biological System:


Protease Assignment Confidence:


Evidence Names:


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Lab:



Protein Neighborhood

Domains & Features

1 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    Q96A23-1-unknown MKKMSN... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    Q96A23-1-unknown MKKMSN... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt102704

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...RTLAP 557 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    ...RTLAP 557 inferred from isoform by sequence similarity unknown TopFIND inferred from TCt67180

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)