TopFIND 4.0

Q96AD5: Patatin-like phospholipase domain-containing protein 2

General Information

Protein names
- Patatin-like phospholipase domain-containing protein 2
- 3.1.1.3
- Adipose triglyceride lipase
- Calcium-independent phospholipase A2
- Desnutrin
- IPLA2-zeta
- Pigment epithelium-derived factor
- TTS2.2
- Transport-secretion protein 2
- TTS2
Gene names PNPLA2
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID Q96AD5

3

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MFPREKTWNI SFAGCGFLGV YYVGVASCLR EHAPFLVANA THIYGASAGA LTATALVTGV 
        70         80         90        100        110        120 
CLGEAGAKFI EVSKEARKRF LGPLHPSFNL VKIIRSFLLK VLPADSHEHA SGRLGISLTR 
       130        140        150        160        170        180 
VSDGENVIIS HFNSKDELIQ ANVCSGFIPV YCGLIPPSLQ GVRYVDGGIS DNLPLYELKN 
       190        200        210        220        230        240 
TITVSPFSGE SDICPQDSST NIHELRVTNT SIQFNLRNLY RLSKALFPPE PLVLREMCKQ 
       250        260        270        280        290        300 
GYRDGLRFLQ RNGLLNRPNP LLALPPARPH GPEDKDQAVE SAQAEDYSQL PGEDHILEHL 
       310        320        330        340        350        360 
PARLNEALLE ACVEPTDLLT TLSNMLPVRL ATAMMVPYTL PLESALSFTI RLLEWLPDVP 
       370        380        390        400        410        420 
EDIRWMKEQT GSICQYLVMR AKRKLGRHLP SRLPEQVELR RVQSLPSVPL SCAAYREALP 
       430        440        450        460        470        480 
GWMRNNLSLG DALAKWEECQ RQLLLGLFCT NVAFPPEALR MRAPADPAPA PADPASPQHQ 
       490        500    
LAGPAPLLST PAPEARPVIG ALGL

Isoforms

- Isoform 2 of Patatin-like phospholipase domain-containing protein 2

Sequence View

        10         20         30         40         50         60 
MFPREKTWNI SFAGCGFLGV YYVGVASCLR EHAPFLVANA THIYGASAGA LTATALVTGV 
        70         80         90        100        110        120 
CLGEAGAKFI EVSKEARKRF LGPLHPSFNL VKIIRSFLLK VLPADSHEHA SGRLGISLTR 
       130        140        150        160        170        180 
VSDGENVIIS HFNSKDELIQ ANVCSGFIPV YCGLIPPSLQ GVRYVDGGIS DNLPLYELKN 
       190        200        210        220        230        240 
TITVSPFSGE SDICPQDSST NIHELRVTNT SIQFNLRNLY RLSKALFPPE PLVLREMCKQ 
       250        260        270        280        290        300 
GYRDGLRFLQ RNGLLNRPNP LLALPPARPH GPEDKDQAVE SAQAEDYSQL PGEDHILEHL 
       310        320        330        340        350        360 
PARLNEALLE ACVEPTDLLT TLSNMLPVRL ATAMMVPYTL PLESALSFTI RLLEWLPDVP 
       370        380        390        400        410        420 
EDIRWMKEQT GSICQYLVMR AKRKLGRHLP SRLPEQVELR RVQSLPSVPL SCAAYREALP 
       430        440        450        460        470        480 
GWMRNNLSLG DALAKWEECQ RQLLLGLFCT NVAFPPEALR MRAPADPAPA PADPASPQHQ 
       490        500    
LAGPAPLLST PAPEARPVIG ALGL



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Protein Neighborhood

Domains & Features

3 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    Q96AD5-1-unknown MFPREK... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    Q96AD5-104-unknown ADSHEH... 104 inferred from electronic annotation unknown TISdb inferred from TISdb
    Q96AD5-325-unknown MLPVRL... 325 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt85587

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...GALGL 504 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    ...GALGL 504 inferred from isoform by sequence similarity unknown TopFIND inferred from TCt81205

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)