TopFIND 4.0

Q96BT3: Centromere protein T

General Information

Protein names
- Centromere protein T
- CENP-T
- Interphase centromere complex protein 22
Gene names CENPT
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID Q96BT3

1

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MADHNPDSDS TPRTLLRRVL DTADPRTPRR PRSARAGARR ALLETASPRK LSGQTRTIAR 
        70         80         90        100        110        120 
GRSHGARSVG RSAHIQASGH LEEQTPRTLL KNILLTAPES SILMPESVVK PVPAPQAVQP 
       130        140        150        160        170        180 
SRQESSCGSL ELQLPELEPP TTLAPGLLAP GRRKQRLRLS VFQQGVDQGL SLSQEPQGNA 
       190        200        210        220        230        240 
DASSLTRSLN LTFATPLQPQ SVQRPGLARR PPARRAVDVG AFLRDLRDTS LAPPNIVLED 
       250        260        270        280        290        300 
TQPFSQPMVG SPNVYHSLPC TPHTGAEDAE QAAGRKTQSS GPGLQKNSPG KPAQFLAGEA 
       310        320        330        340        350        360 
EEVNAFALGF LSTSSGVSGE DEVEPLHDGV EEAEKKMEEE GVSVSEMEAT GAQGPSRVEE 
       370        380        390        400        410        420 
AEGHTEVTEA EGSQGTAEAD GPGASSGDED ASGRAASPES ASSTPESLQA RRHHQFLEPA 
       430        440        450        460        470        480 
PAPGAAVLSS EPAEPLLVRH PPRPRTTGPR PRQDPHKAGL SHYVKLFSFY AKMPMERKAL 
       490        500        510        520        530        540 
EMVEKCLDKY FQHLCDDLEV FAAHAGRKTV KPEDLELLMR RQGLVTDQVS LHVLVERHLP 
       550        560    
LEYRQLLIPC AYSGNSVFPA Q

Isoforms

- Isoform 2 of Centromere protein T - Isoform 3 of Centromere protein T

Sequence View

        10         20         30         40         50         60 
MADHNPDSDS TPRTLLRRVL DTADPRTPRR PRSARAGARR ALLETASPRK LSGQTRTIAR 
        70         80         90        100        110        120 
GRSHGARSVG RSAHIQASGH LEEQTPRTLL KNILLTAPES SILMPESVVK PVPAPQAVQP 
       130        140        150        160        170        180 
SRQESSCGSL ELQLPELEPP TTLAPGLLAP GRRKQRLRLS VFQQGVDQGL SLSQEPQGNA 
       190        200        210        220        230        240 
DASSLTRSLN LTFATPLQPQ SVQRPGLARR PPARRAVDVG AFLRDLRDTS LAPPNIVLED 
       250        260        270        280        290        300 
TQPFSQPMVG SPNVYHSLPC TPHTGAEDAE QAAGRKTQSS GPGLQKNSPG KPAQFLAGEA 
       310        320        330        340        350        360 
EEVNAFALGF LSTSSGVSGE DEVEPLHDGV EEAEKKMEEE GVSVSEMEAT GAQGPSRVEE 
       370        380        390        400        410        420 
AEGHTEVTEA EGSQGTAEAD GPGASSGDED ASGRAASPES ASSTPESLQA RRHHQFLEPA 
       430        440        450        460        470        480 
PAPGAAVLSS EPAEPLLVRH PPRPRTTGPR PRQDPHKAGL SHYVKLFSFY AKMPMERKAL 
       490        500        510        520        530        540 
EMVEKCLDKY FQHLCDDLEV FAAHAGRKTV KPEDLELLMR RQGLVTDQVS LHVLVERHLP 
       550        560    
LEYRQLLIPC AYSGNSVFPA Q         10         20         30         40         50         60 
MADHNPDSDS TPRTLLRRVL DTADPRTPRR PRSARAGARR ALLETASPRK LSGQTRTIAR 
        70         80         90        100        110        120 
GRSHGARSVG RSAHIQASGH LEEQTPRTLL KNILLTAPES SILMPESVVK PVPAPQAVQP 
       130        140        150        160        170        180 
SRQESSCGSL ELQLPELEPP TTLAPGLLAP GRRKQRLRLS VFQQGVDQGL SLSQEPQGNA 
       190        200        210        220        230        240 
DASSLTRSLN LTFATPLQPQ SVQRPGLARR PPARRAVDVG AFLRDLRDTS LAPPNIVLED 
       250        260        270        280        290        300 
TQPFSQPMVG SPNVYHSLPC TPHTGAEDAE QAAGRKTQSS GPGLQKNSPG KPAQFLAGEA 
       310        320        330        340        350        360 
EEVNAFALGF LSTSSGVSGE DEVEPLHDGV EEAEKKMEEE GVSVSEMEAT GAQGPSRVEE 
       370        380        390        400        410        420 
AEGHTEVTEA EGSQGTAEAD GPGASSGDED ASGRAASPES ASSTPESLQA RRHHQFLEPA 
       430        440        450        460        470        480 
PAPGAAVLSS EPAEPLLVRH PPRPRTTGPR PRQDPHKAGL SHYVKLFSFY AKMPMERKAL 
       490        500        510        520        530        540 
EMVEKCLDKY FQHLCDDLEV FAAHAGRKTV KPEDLELLMR RQGLVTDQVS LHVLVERHLP 
       550        560    
LEYRQLLIPC AYSGNSVFPA Q



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Protein Neighborhood

Domains & Features

1 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    Q96BT3-1-unknown MADHNP... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    Q96BT3-1-unknown MADHNP... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt70321
    Q96BT3-1-unknown MADHNP... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt70322

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...VFPAQ 561 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)