TopFIND 4.0

Q96CS7: Pleckstrin homology domain-containing family B member 2

General Information

Protein names
- Pleckstrin homology domain-containing family B member 2
- PH domain-containing family B member 2
- Evectin-2
Gene names PLEKHB2
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID Q96CS7

1

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MAFVKSGWLL RQSTILKRWK KNWFDLWSDG HLIYYDDQTR QNIEDKVHMP MDCINIRTGQ 
        70         80         90        100        110        120 
ECRDTQPPDG KSKDCMLQIV CRDGKTISLC AESTDDCLAW KFTLQDSRTN TAYVGSAVMT 
       130        140        150        160        170        180 
DETSVVSSPP PYTAYAAPAP EQAYGYGPYG GAYPPGTQVV YAANGQAYAV PYQYPYAGLY 
       190        200        210        220    
GQQPANQVII RERYRDNDSD LALGMLAGAA TGMALGSLFW VF

Isoforms

- Isoform 2 of Pleckstrin homology domain-containing family B member 2 - Isoform 3 of Pleckstrin homology domain-containing family B member 2 - Isoform 4 of Pleckstrin homology domain-containing family B member 2 - Isoform 5 of Pleckstrin homology domain-containing family B member 2 - Isoform 6 of Pleckstrin homology domain-containing family B member 2

Sequence View

        10         20         30         40         50         60 
MAFVKSGWLL RQSTILKRWK KNWFDLWSDG HLIYYDDQTR QNIEDKVHMP MDCINIRTGQ 
        70         80         90        100        110        120 
ECRDTQPPDG KSKDCMLQIV CRDGKTISLC AESTDDCLAW KFTLQDSRTN TAYVGSAVMT 
       130        140        150        160        170        180 
DETSVVSSPP PYTAYAAPAP EQAYGYGPYG GAYPPGTQVV YAANGQAYAV PYQYPYAGLY 
       190        200        210        220    
GQQPANQVII RERYRDNDSD LALGMLAGAA TGMALGSLFW VF         10         20         30         40         50         60 
MAFVKSGWLL RQSTILKRWK KNWFDLWSDG HLIYYDDQTR QNIEDKVHMP MDCINIRTGQ 
        70         80         90        100        110        120 
ECRDTQPPDG KSKDCMLQIV CRDGKTISLC AESTDDCLAW KFTLQDSRTN TAYVGSAVMT 
       130        140        150        160        170        180 
DETSVVSSPP PYTAYAAPAP EQAYGYGPYG GAYPPGTQVV YAANGQAYAV PYQYPYAGLY 
       190        200        210        220    
GQQPANQVII RERYRDNDSD LALGMLAGAA TGMALGSLFW VF         10         20         30         40         50         60 
MAFVKSGWLL RQSTILKRWK KNWFDLWSDG HLIYYDDQTR QNIEDKVHMP MDCINIRTGQ 
        70         80         90        100        110        120 
ECRDTQPPDG KSKDCMLQIV CRDGKTISLC AESTDDCLAW KFTLQDSRTN TAYVGSAVMT 
       130        140        150        160        170        180 
DETSVVSSPP PYTAYAAPAP EQAYGYGPYG GAYPPGTQVV YAANGQAYAV PYQYPYAGLY 
       190        200        210        220    
GQQPANQVII RERYRDNDSD LALGMLAGAA TGMALGSLFW VF         10         20         30         40         50         60 
MAFVKSGWLL RQSTILKRWK KNWFDLWSDG HLIYYDDQTR QNIEDKVHMP MDCINIRTGQ 
        70         80         90        100        110        120 
ECRDTQPPDG KSKDCMLQIV CRDGKTISLC AESTDDCLAW KFTLQDSRTN TAYVGSAVMT 
       130        140        150        160        170        180 
DETSVVSSPP PYTAYAAPAP EQAYGYGPYG GAYPPGTQVV YAANGQAYAV PYQYPYAGLY 
       190        200        210        220    
GQQPANQVII RERYRDNDSD LALGMLAGAA TGMALGSLFW VF         10         20         30         40         50         60 
MAFVKSGWLL RQSTILKRWK KNWFDLWSDG HLIYYDDQTR QNIEDKVHMP MDCINIRTGQ 
        70         80         90        100        110        120 
ECRDTQPPDG KSKDCMLQIV CRDGKTISLC AESTDDCLAW KFTLQDSRTN TAYVGSAVMT 
       130        140        150        160        170        180 
DETSVVSSPP PYTAYAAPAP EQAYGYGPYG GAYPPGTQVV YAANGQAYAV PYQYPYAGLY 
       190        200        210        220    
GQQPANQVII RERYRDNDSD LALGMLAGAA TGMALGSLFW VF



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Directness:


Physiological Relevance:


Evidence Codes:


Methodology:


Perturbation of System:


Biological System:


Protease Assignment Confidence:


Evidence Names:


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Protein Neighborhood

Domains & Features

1 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini

C-termini

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)