TopFIND 4.0

Q96DC9: Ubiquitin thioesterase OTUB2

General Information

Protein names
- Ubiquitin thioesterase OTUB2
- 3.4.19.12 {ECO:0000269|PubMed:23827681}
- Deubiquitinating enzyme OTUB2
- OTU domain-containing ubiquitin aldehyde-binding protein 2
- Otubain-2
- Ubiquitin-specific-processing protease OTUB2
Gene names OTUB2
Organism Homo sapiens
Protease Family
Protease ID C65.002
Chromosome location
UniProt ID Q96DC9

1

N-termini

2

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MSETSFNLIS EKCDILSILR DHPENRIYRR KIEELSKRFT AIRKTKGDGN CFYRALGYSY 
        70         80         90        100        110        120 
LESLLGKSRE IFKFKERVLQ TPNDLLAAGF EEHKFRNFFN AFYSVVELVE KDGSVSSLLK 
       130        140        150        160        170        180 
VFNDQSASDH IVQFLRLLTS AFIRNRADFF RHFIDEEMDI KDFCTHEVEP MATECDHIQI 
       190        200        210        220        230    
TALSQALSIA LQVEYVDEMD TALNHHVFPE AATPSVYLLY KTSHYNILYA ADKH

Isoforms

- Isoform 2 of Ubiquitin thioesterase OTUB2

Sequence View

        10         20         30         40         50         60 
MSETSFNLIS EKCDILSILR DHPENRIYRR KIEELSKRFT AIRKTKGDGN CFYRALGYSY 
        70         80         90        100        110        120 
LESLLGKSRE IFKFKERVLQ TPNDLLAAGF EEHKFRNFFN AFYSVVELVE KDGSVSSLLK 
       130        140        150        160        170        180 
VFNDQSASDH IVQFLRLLTS AFIRNRADFF RHFIDEEMDI KDFCTHEVEP MATECDHIQI 
       190        200        210        220        230    
TALSQALSIA LQVEYVDEMD TALNHHVFPE AATPSVYLLY KTSHYNILYA ADKH



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Protein Neighborhood

Domains & Features

1 N-termini - 2 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    Q96DC9-1-unknown MSETSF... 1 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    Q96DC9-1-unknown MSETSF... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt83918

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...REIFKF 73 inferred from isoform by sequence similarity unknown TopFIND inferred from TCt79536
    ...AADKH 234 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)