TopFIND 4.0

Q96E52: Metalloendopeptidase OMA1, mitochondrial

General Information

Protein names
- Metalloendopeptidase OMA1, mitochondrial
- 3.4.24.-
- Metalloprotease-related protein 1
- MPRP-1
- Overlapping with the m-AAA protease 1 homolog
Gene names OMA1
Organism Homo sapiens
Protease Family
Protease ID M48.017
Chromosome location
UniProt ID Q96E52

2

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MSFICGLQSA ARNHVFFRFN SLSNWRKCNT LASTSRGCHQ VQVNHIVNKY QGLGVNQCDR 
        70         80         90        100        110        120 
WSFLPGNFHF YSTFNNKRTG GLSSTKSKEI WRITSKCTVW NDAFSRQLLI KEVTAVPSLS 
       130        140        150        160        170        180 
VLHPLSPASI RAIRNFHTSP RFQAAPVPLL LMILKPVQKL FAIIVGRGIR KWWQALPPNK 
       190        200        210        220        230        240 
KEVVKENIRK NKWKLFLGLS SFGLLFVVFY FTHLEVSPIT GRSKLLLLGK EQFRLLSELE 
       250        260        270        280        290        300 
YEAWMEEFKN DMLTEKDARY LAVKEVLCHL IECNKDVPGI SQINWVIHVV DSPIINAFVL 
       310        320        330        340        350        360 
PNGQMFVFTG FLNSVTDIHQ LSFLLGHEIA HAVLGHAAEK AGMVHLLDFL GMIFLTMIWA 
       370        380        390        400        410        420 
ICPRDSLALL CQWIQSKLQE YMFNRPYSRK LEAEADKIGL LLAAKACADI RASSVFWQQM 
       430        440        450        460        470        480 
EFVDSLHGQP KMPEWLSTHP SHGNRVEYLD RLIPQALKIR EMCNCPPLSN PDPRLLFKLS 
       490        500        510        520    
TKHFLEESEK EDLNITKKQK MDTLPIQKQE QIPLTYIVEK RTGS

Isoforms

- Isoform 2 of Metalloendopeptidase OMA1, mitochondrial

Sequence View

        10         20         30         40         50         60 
MSFICGLQSA ARNHVFFRFN SLSNWRKCNT LASTSRGCHQ VQVNHIVNKY QGLGVNQCDR 
        70         80         90        100        110        120 
WSFLPGNFHF YSTFNNKRTG GLSSTKSKEI WRITSKCTVW NDAFSRQLLI KEVTAVPSLS 
       130        140        150        160        170        180 
VLHPLSPASI RAIRNFHTSP RFQAAPVPLL LMILKPVQKL FAIIVGRGIR KWWQALPPNK 
       190        200        210        220        230        240 
KEVVKENIRK NKWKLFLGLS SFGLLFVVFY FTHLEVSPIT GRSKLLLLGK EQFRLLSELE 
       250        260        270        280        290        300 
YEAWMEEFKN DMLTEKDARY LAVKEVLCHL IECNKDVPGI SQINWVIHVV DSPIINAFVL 
       310        320        330        340        350        360 
PNGQMFVFTG FLNSVTDIHQ LSFLLGHEIA HAVLGHAAEK AGMVHLLDFL GMIFLTMIWA 
       370        380        390        400        410        420 
ICPRDSLALL CQWIQSKLQE YMFNRPYSRK LEAEADKIGL LLAAKACADI RASSVFWQQM 
       430        440        450        460        470        480 
EFVDSLHGQP KMPEWLSTHP SHGNRVEYLD RLIPQALKIR EMCNCPPLSN PDPRLLFKLS 
       490        500        510        520    
TKHFLEESEK EDLNITKKQK MDTLPIQKQE QIPLTYIVEK RTGS



Filter Information:


(REFRESH)

Directness:


Physiological Relevance:


Evidence Codes:


Methodology:


Perturbation of System:


Biological System:


Protease Assignment Confidence:


Evidence Names:


Database:


Lab:



Protein Neighborhood

Domains & Features

2 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    Q96E52-1-unknown MSFICG... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt83754
    Q96E52-14-unknown HVFFRF... 14 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    Q96E52-14-unknown HVFFRF... 14 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt111765

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...KRTGS 524 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)