Q96EA4: Protein Spindly {ECO:0000255|HAMAP-Rule:MF_03041}

General Information

Protein names	- Protein Spindly {ECO:0000255\|HAMAP-Rule:MF_03041} - hSpindly - Arsenite-related gene 1 protein - Coiled-coil domain-containing protein 99 {ECO:0000255\|HAMAP-Rule:MF_03041} - Rhabdomyosarcoma antigen MU-RMS-40.4A - Spindle apparatus coiled-coil domain-containing protein 1 {ECO:0000255\|HAMAP-Rule:MF_03041}
Gene names	SPDL1
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q96EA4

2 N-termini

1 C-termini

0 Cleavages

0 Substrates

Sequence

Isoforms

- Isoform 2 of Protein Spindly - Isoform 3 of Protein Spindly

Sequence View

        10         20         30         40         50         60
MEADIITNLR CRLKEAEEER LKAAQYGLQL VESQNELQNQ LDKCRNEMMT MTESYEQEKY
        70         80         90        100        110        120
TLQREVELKS RMLESLSCEC EAIKQQQKMH LEKLEEQLSR SHGQEVNELK TKIEKLKVEL
       130        140        150        160        170        180
DEARLSEKQL KHQVDHQKEL LSCKSEELRV MSERVQESMS SEMLALQIEL TEMESMKTTL
       190        200        210        220        230        240
KEEVNELQYR QEQLELLITN LMRQVDRLKE EKEEREKEAV SYYNALEKAR VANQDLQVQL
       250        260        270        280        290        300
DQALQQALDP NSKGNSLFAE VEDRRAAMER QLISMKVKYQ SLKKQNVFNR EQMQRMKLQI
       310        320        330        340        350        360
ATLLQMKGSQ TEFEQQERLL AMLEQKNGEI KHLLGEIRNL EKFKNLYDSM ESKPSVDSGT
       370        380        390        400        410        420
LEDNTYYTDL LQMKLDNLNK EIESTKGELS IQRMKALFES QRALDIERKL FANERCLQLS
       430        440        450        460        470        480
ESENMKLRAK LDELKLKYEP EETVEVPVLK KRREVLPVDI TTAKDACVNN SALGGEVYRL
       490        500        510        520        530        540
PPQKEETQSC PNSLEDNNLQ LEKSVSIYTP VVSLSPHKNL PVDMQLKKEK KCVKLIGVPA
       550        560        570        580        590        600
DAEALSERSG NTPNSPRLAA ESKLQTEVKE GKETSSKLEK ETCKKLHPIL YVSSKSTPET

QCPQQ         10         20         30         40         50         60
MEADIITNLR CRLKEAEEER LKAAQYGLQL VESQNELQNQ LDKCRNEMMT MTESYEQEKY
        70         80         90        100        110        120
TLQREVELKS RMLESLSCEC EAIKQQQKMH LEKLEEQLSR SHGQEVNELK TKIEKLKVEL
       130        140        150        160        170        180
DEARLSEKQL KHQVDHQKEL LSCKSEELRV MSERVQESMS SEMLALQIEL TEMESMKTTL
       190        200        210        220        230        240
KEEVNELQYR QEQLELLITN LMRQVDRLKE EKEEREKEAV SYYNALEKAR VANQDLQVQL
       250        260        270        280        290        300
DQALQQALDP NSKGNSLFAE VEDRRAAMER QLISMKVKYQ SLKKQNVFNR EQMQRMKLQI
       310        320        330        340        350        360
ATLLQMKGSQ TEFEQQERLL AMLEQKNGEI KHLLGEIRNL EKFKNLYDSM ESKPSVDSGT
       370        380        390        400        410        420
LEDNTYYTDL LQMKLDNLNK EIESTKGELS IQRMKALFES QRALDIERKL FANERCLQLS
       430        440        450        460        470        480
ESENMKLRAK LDELKLKYEP EETVEVPVLK KRREVLPVDI TTAKDACVNN SALGGEVYRL
       490        500        510        520        530        540
PPQKEETQSC PNSLEDNNLQ LEKSVSIYTP VVSLSPHKNL PVDMQLKKEK KCVKLIGVPA
       550        560        570        580        590        600
DAEALSERSG NTPNSPRLAA ESKLQTEVKE GKETSSKLEK ETCKKLHPIL YVSSKSTPET

QCPQQ

Filter Information:

(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

2 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMID)
Q96EA4-1-Acetylation	MEADII...	1	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
Q96EA4-1-Acetylation	MEADII...	1	acetylation-		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345
Q96EA4-1-Acetylation	MEADII...	1	acetylation-		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345
Q96EA4-1-Acetylation	MEADII...	1	acetylation-	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt99908
Q96EA4-1-Acetylation	MEADII...	1	acetylation-	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt99909
Q96EA4-1-unknown	MEADII...	1		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt90406
Q96EA4-1-unknown	MEADII...	1		inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TNt90407

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Evidence name
...QCPQQ	605	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
...QCPQQ	605	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt86024
...QCPQQ	605	inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TCt86025

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)