Q96EZ8: Microspherule protein 1

General Information

Protein names	- Microspherule protein 1 - 58 kDa microspherule protein - Cell cycle-regulated factor p78 - INO80 complex subunit J - MCRS2
Gene names	MCRS1
Organism	Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID	Q96EZ8

4 N-termini

6 C-termini

0 Cleavages

0 Substrates

Sequence

Isoforms

- Isoform 2 of Microspherule protein 1 - Isoform 3 of Microspherule protein 1 - Isoform 4 of Microspherule protein 1

Sequence View

        10         20         30         40         50         60
MDKDSQGLLD SSLMASGTAS RSEDEESLAG QKRASSQALG TIPKRRSSSR FIKRKKFDDE
        70         80         90        100        110        120
LVESSLAKSS TRAKGASGVE PGRCSGSEPS SSEKKKVSKA PSTPVPPSPA PAPGLTKRVK
       130        140        150        160        170        180
KSKQPLQVTK DLGRWKPADD LLLINAVLQT NDLTSVHLGV KFSCRFTLRE VQERWYALLY
       190        200        210        220        230        240
DPVISKLACQ AMRQLHPEAI AAIQSKALFS KAEEQLLSKV GSTSQPTLET FQDLLHRHPD
       250        260        270        280        290        300
AFYLARTAKA LQAHWQLMKQ YYLLEDQTVQ PLPKGDQVLN FSDAEDLIDD SKLKDMRDEV
       310        320        330        340        350        360
LEHELMVADR RQKREIRQLE QELHKWQVLV DSITGMSSPD FDNQTLAVLR GRMVRYLMRS
       370        380        390        400        410        420
REITLGRATK DNQIDVDLSL EGPAWKISRK QGVIKLKNNG DFFIANEGRR PIYIDGRPVL
       430        440        450        460
CGSKWRLSNN SVVEIASLRF VFLINQDLIA LIRAEAAKIT PQ         10         20         30         40         50         60
MDKDSQGLLD SSLMASGTAS RSEDEESLAG QKRASSQALG TIPKRRSSSR FIKRKKFDDE
        70         80         90        100        110        120
LVESSLAKSS TRAKGASGVE PGRCSGSEPS SSEKKKVSKA PSTPVPPSPA PAPGLTKRVK
       130        140        150        160        170        180
KSKQPLQVTK DLGRWKPADD LLLINAVLQT NDLTSVHLGV KFSCRFTLRE VQERWYALLY
       190        200        210        220        230        240
DPVISKLACQ AMRQLHPEAI AAIQSKALFS KAEEQLLSKV GSTSQPTLET FQDLLHRHPD
       250        260        270        280        290        300
AFYLARTAKA LQAHWQLMKQ YYLLEDQTVQ PLPKGDQVLN FSDAEDLIDD SKLKDMRDEV
       310        320        330        340        350        360
LEHELMVADR RQKREIRQLE QELHKWQVLV DSITGMSSPD FDNQTLAVLR GRMVRYLMRS
       370        380        390        400        410        420
REITLGRATK DNQIDVDLSL EGPAWKISRK QGVIKLKNNG DFFIANEGRR PIYIDGRPVL
       430        440        450        460
CGSKWRLSNN SVVEIASLRF VFLINQDLIA LIRAEAAKIT PQ         10         20         30         40         50         60
MDKDSQGLLD SSLMASGTAS RSEDEESLAG QKRASSQALG TIPKRRSSSR FIKRKKFDDE
        70         80         90        100        110        120
LVESSLAKSS TRAKGASGVE PGRCSGSEPS SSEKKKVSKA PSTPVPPSPA PAPGLTKRVK
       130        140        150        160        170        180
KSKQPLQVTK DLGRWKPADD LLLINAVLQT NDLTSVHLGV KFSCRFTLRE VQERWYALLY
       190        200        210        220        230        240
DPVISKLACQ AMRQLHPEAI AAIQSKALFS KAEEQLLSKV GSTSQPTLET FQDLLHRHPD
       250        260        270        280        290        300
AFYLARTAKA LQAHWQLMKQ YYLLEDQTVQ PLPKGDQVLN FSDAEDLIDD SKLKDMRDEV
       310        320        330        340        350        360
LEHELMVADR RQKREIRQLE QELHKWQVLV DSITGMSSPD FDNQTLAVLR GRMVRYLMRS
       370        380        390        400        410        420
REITLGRATK DNQIDVDLSL EGPAWKISRK QGVIKLKNNG DFFIANEGRR PIYIDGRPVL
       430        440        450        460
CGSKWRLSNN SVVEIASLRF VFLINQDLIA LIRAEAAKIT PQ

Filter Information:

(REFRESH)

Directness:

Physiological Relevance:

Evidence Codes:

Methodology:

Perturbation of System:

Biological System:

Protease Assignment Confidence:

Evidence Names:

Database:

Lab:

Protein Neighborhood

Domains & Features

4 N-termini - 6 C-termini - 0 Cleavages - 0 Substrates

N-termini

Name	Sequence	Position	Modification	Evidence type	Method	Source (database)	Evidence name
Q96EZ8-1-Acetylation	MDKDSQ...	1	acetylation-	inferred from electronic annotation	electronic annotation	UniProtKB	inferred from uniprot
Q96EZ8-14-unknown	MASGTA...	14		inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt80665
Q96EZ8-14-unknown	MASGTA...	14		inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000447514
Q96EZ8-14-unknown	MASGTA...	14		inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt97304
Q96EZ8-192-unknown	MRQLHP...	192		inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt80666
Q96EZ8-192-unknown	MRQLHP...	192		inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000444982
Q96EZ8-192-unknown	MRQLHP...	192		inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt97365
Q96EZ8-192-unknown	MRQLHP...	192		inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt97366
Q96EZ8-292-unknown	KLKDMR...	292		inferred from electronic annotation	unknown	Ensembl	inferred from ensembl protein ENSP00000448947
Q96EZ8-292-unknown	KLKDMR...	292		inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt198780
Q96EZ8-292-unknown	KLKDMR...	292		inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt198781
Q96EZ8-292-unknown	KLKDMR...	292		inferred from isoform by sequence similarity	unknown	TopFIND	inferred from TNt198782

C-termini

Sequence	Position	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)
...KPADDL	140	inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000447592
...KPADDL	140	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt154874
...KPADDL	140	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt154875
...DPVISK	185	inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000449343
...DPVISK	185	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt155472
...DPVISK	185	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt155473
...AAIQSK	205	inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000450352
...AAIQSK	205	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt155696
...AAIQSK	205	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt155697
...QVLVDS	331	inferred from electronic annotation	unknown	Ensembl		inferred from ensembl protein ENSP00000447514
...KITPQ	462	inferred from electronic annotation	electronic annotation	UniProtKB		inferred from uniprot
...KITPQ	462	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt76284
...KITPQ	462	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt76283
...KITPQ	462	inferred from isoform by sequence similarity	unknown	TopFIND		inferred from TCt76282
...KITPQ	462		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345,
...KITPQ	462		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345,
...KITPQ	462		COFRADIC		Gevaert K.	Van Damme P et al.: Complementary positional proteomics for screening substrates...	20526345,
...KITPQ	462		COFRADIC		Gevaert K.	Van Damme P et al.: PC3-cells, Complementary positional proteomics for screening substrates...	20526345,

Cleavages

Protease	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)

Substrates

Substrate	Position	Sequence	Evidence type	Method	Source (database)	Source (Lab)	Evidence name	Publications (PMIDs)