TopFIND 4.0

Q96FL8: Multidrug and toxin extrusion protein 1

General Information

Protein names
- Multidrug and toxin extrusion protein 1
- MATE-1
- hMATE-1
- Solute carrier family 47 member 1
Gene names SLC47A1
Organism Homo sapiens
Protease Family
Protease ID
Chromosome location
UniProt ID Q96FL8

2

N-termini

1

C-termini

0

Cleavages

0

Substrates

Sequence

        10         20         30         40         50         60 
MEAPEEPAPV RGGPEATLEV RGSRCLRLSA FREELRALLV LAGPAFLVQL MVFLISFISS 
        70         80         90        100        110        120 
VFCGHLGKLE LDAVTLAIAV INVTGVSVGF GLSSACDTLI SQTYGSQNLK HVGVILQRSA 
       130        140        150        160        170        180 
LVLLLCCFPC WALFLNTQHI LLLFRQDPDV SRLTQTYVTI FIPALPATFL YMLQVKYLLN 
       190        200        210        220        230        240 
QGIVLPQIVT GVAANLVNAL ANYLFLHQLH LGVIGSALAN LISQYTLALL LFLYILGKKL 
       250        260        270        280        290        300 
HQATWGGWSL ECLQDWASFL RLAIPSMLML CMEWWAYEVG SFLSGILGMV ELGAQSIVYE 
       310        320        330        340        350        360 
LAIIVYMVPA GFSVAASVRV GNALGAGDME QARKSSTVSL LITVLFAVAF SVLLLSCKDH 
       370        380        390        400        410        420 
VGYIFTTDRD IINLVAQVVP IYAVSHLFEA LACTSGGVLR GSGNQKVGAI VNTIGYYVVG 
       430        440        450        460        470        480 
LPIGIALMFA TTLGVMGLWS GIIICTVFQA VCFLGFIIQL NWKKACQQAQ VHANLKVNNV 
       490        500        510        520        530        540 
PRSGNSALPQ DPLHPGCPEN LEGILTNDVG KTGEPQSDQQ MRQEEPLPEH PQDGAKLSRK 
       550        560        570    
QLVLRRGLLL LGVFLILLVG ILVRFYVRIQ 

Isoforms

- Isoform 2 of Multidrug and toxin extrusion protein 1 - Isoform 3 of Multidrug and toxin extrusion protein 1

Sequence View

        10         20         30         40         50         60 
MEAPEEPAPV RGGPEATLEV RGSRCLRLSA FREELRALLV LAGPAFLVQL MVFLISFISS 
        70         80         90        100        110        120 
VFCGHLGKLE LDAVTLAIAV INVTGVSVGF GLSSACDTLI SQTYGSQNLK HVGVILQRSA 
       130        140        150        160        170        180 
LVLLLCCFPC WALFLNTQHI LLLFRQDPDV SRLTQTYVTI FIPALPATFL YMLQVKYLLN 
       190        200        210        220        230        240 
QGIVLPQIVT GVAANLVNAL ANYLFLHQLH LGVIGSALAN LISQYTLALL LFLYILGKKL 
       250        260        270        280        290        300 
HQATWGGWSL ECLQDWASFL RLAIPSMLML CMEWWAYEVG SFLSGILGMV ELGAQSIVYE 
       310        320        330        340        350        360 
LAIIVYMVPA GFSVAASVRV GNALGAGDME QARKSSTVSL LITVLFAVAF SVLLLSCKDH 
       370        380        390        400        410        420 
VGYIFTTDRD IINLVAQVVP IYAVSHLFEA LACTSGGVLR GSGNQKVGAI VNTIGYYVVG 
       430        440        450        460        470        480 
LPIGIALMFA TTLGVMGLWS GIIICTVFQA VCFLGFIIQL NWKKACQQAQ VHANLKVNNV 
       490        500        510        520        530        540 
PRSGNSALPQ DPLHPGCPEN LEGILTNDVG KTGEPQSDQQ MRQEEPLPEH PQDGAKLSRK 
       550        560        570    
QLVLRRGLLL LGVFLILLVG ILVRFYVRIQ          10         20         30         40         50         60 
MEAPEEPAPV RGGPEATLEV RGSRCLRLSA FREELRALLV LAGPAFLVQL MVFLISFISS 
        70         80         90        100        110        120 
VFCGHLGKLE LDAVTLAIAV INVTGVSVGF GLSSACDTLI SQTYGSQNLK HVGVILQRSA 
       130        140        150        160        170        180 
LVLLLCCFPC WALFLNTQHI LLLFRQDPDV SRLTQTYVTI FIPALPATFL YMLQVKYLLN 
       190        200        210        220        230        240 
QGIVLPQIVT GVAANLVNAL ANYLFLHQLH LGVIGSALAN LISQYTLALL LFLYILGKKL 
       250        260        270        280        290        300 
HQATWGGWSL ECLQDWASFL RLAIPSMLML CMEWWAYEVG SFLSGILGMV ELGAQSIVYE 
       310        320        330        340        350        360 
LAIIVYMVPA GFSVAASVRV GNALGAGDME QARKSSTVSL LITVLFAVAF SVLLLSCKDH 
       370        380        390        400        410        420 
VGYIFTTDRD IINLVAQVVP IYAVSHLFEA LACTSGGVLR GSGNQKVGAI VNTIGYYVVG 
       430        440        450        460        470        480 
LPIGIALMFA TTLGVMGLWS GIIICTVFQA VCFLGFIIQL NWKKACQQAQ VHANLKVNNV 
       490        500        510        520        530        540 
PRSGNSALPQ DPLHPGCPEN LEGILTNDVG KTGEPQSDQQ MRQEEPLPEH PQDGAKLSRK 
       550        560        570    
QLVLRRGLLL LGVFLILLVG ILVRFYVRIQ 



Filter Information:


(REFRESH)

Directness:


Physiological Relevance:


Evidence Codes:


Methodology:


Perturbation of System:


Biological System:


Protease Assignment Confidence:


Evidence Names:


Database:


Lab:



Protein Neighborhood

Domains & Features

2 N-termini - 1 C-termini - 0 Cleavages - 0 Substrates

N-termini
    Name Sequence Position Modification Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMID)
    Q96FL8-1-unknown MEAPEE... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt88749
    Q96FL8-1-unknown MEAPEE... 1 inferred from isoform by sequence similarity unknown TopFIND inferred from TNt88750
    Q96FL8-1-Acetylation MEAPEE... 1 acetylation- inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot
    Q96FL8-1-Acetylation MEAPEE... 1 acetylation- inferred from isoform by sequence similarity unknown TopFIND inferred from TNt104743
    Q96FL8-1-Acetylation MEAPEE... 1 acetylation- inferred from isoform by sequence similarity unknown TopFIND inferred from TNt104744

C-termini

    Name Sequence Position Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)
    ...YVRIQ 570 inferred from electronic annotation electronic annotation UniProtKB inferred from uniprot

Cleavages

    Protease Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)

Substrates

    Substrate Position Sequence Evidence type Method Source (database) Source (Lab) Evidence name Publications (PMIDs)